Browse Items (38 total)
- Tags: Department of Pharmaceutical Sciences, 2017
Inhibition Of Angiopoietin-like 3 Expression Is A Potential Mechanism Of Activation Of Lipoprotein Lipase And Of Lipid Lowering By Metformin
Tags: 2017, Arteriosclerosis Thrombosis and Vascular Biology, Burke J R, Cardiovascular System & Cardiology, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drugs, Geldenhuys W J, Hematology, Hyperlipidemia, Journal Article or Conference Abstract Publication, Lin L, Lipases, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana P
The Role Of Amadori-glycation In High Density Lipoprotein Dysfunction And Oxidative Stress In Patients With Diabetes
Tags: 2017, Apolipoproteins, Arteriosclerosis Thrombosis and Vascular Biology, Atherosclerosis, Cardiovascular System & Cardiology, Department of Pharmaceutical Sciences, Golizeh M, Hematology, Ilchenko S, Insulin Resistance, Journal Article or Conference Abstract Publication, Kashyap S, Kasumov T, Lee K, NEOMED College of Pharmacy, Smith J, Wang S H
Metabolic Vulnerability In The Neurodegenerative Disease Glaucoma
Tags: 2017, amyotrophic-lateral-sclerosis, axon, Axonopathy, Department of Pharmaceutical Sciences, Frontiers in neuroscience, glucose-transporter glut3, glycogen-synthase kinase-3, Harun-Or-Rashid M, Inman D M, Journal Article or Conference Abstract Publication, lactate, Mitochondria, monocarboxylate transporters, mouse white-matter, NEOMED College of Pharmacy, neuron lactate-shuttle, Neuropathy, Neurosciences & Neurology, optic, optic-nerve head, retinal ganglion-cells, self-destruction, slow wallerian degeneration, Wallerian degeneration
Engineering Alkoxyphenacyl-Polycarbonate Nanoparticles for Potential Application in Near-Infrared Light-Modulated Drug Delivery via Photon Up-Conversion Process
Tags: 2017, 800 nm, alkoxylphenacyl-based polycarbonates, Andrews J H, Biocompatibility, Chamsaz E A, Chemistry, Department of Pharmaceutical Sciences, Doxorubicin, Drug Release, Journal Article, Journal of nanoscience and nanotechnology, Joy A, luminescence, Materials Science, mesoporous-silica, nanocrystals, Nanotechnology, Near-Infrared Light, NEOMED College of Pharmacy, Oyewumi M O, photodynamic therapy, Physics, release, Science & Technology - Other Topics, Stimuli-responsive, upconverting nanoparticles, uv, Wehrung D
Evaluating the Changing Financial Burdens for Graduating Pharmacists.
Tags: 2017, American journal of pharmaceutical education, Career Choice, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Humans, Income, Mattingly T Joseph 2nd, NEOMED College of Pharmacy, new practitioners, personal finance, Pharmacists/*economics, Pharmacy, Pharmacy/*economics, Salaries and Fringe Benefits/economics, Schools, student debt, Students, Training Support/*economics, Ulbrich Timothy R
It's Time to Broaden the Conversation About the Student Debt Crisis Beyond Rising Tuition Costs.
Tags: *debt, *personal finance, *student loans, 2017, American journal of pharmaceutical education, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Humans, Income, Kirk Loren M, NEOMED College of Pharmacy, Pharmacists/economics, Pharmacy, Pharmacy/*economics, Students, Ulbrich Timothy R
Methods Used by Colleges and Schools of Pharmacy to Prepare Student Pharmacists for Careers in Academia.
Tags: *Career Choice, *Students, 2017, Academia, American journal of pharmaceutical education, Attitude of Health Personnel, Boyle Jaclyn A, Career, Clifford Kalin M, Curriculum, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dy-Boarman Eliza A, Education, Faculty, Graduate, Haines Seena L, Humans, NEOMED College of Pharmacy, Peeters Michael J, Pharmaceutical, Pharmacists, Pharmacy, Pharmacy/*methods, Pharmacy/*organization & administration, Schools, Societies, Student preparation, Summa Maria A, Surveys and Questionnaires, Training, United States, Willson Megan N
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease.
Tags: *Alzheimer Disease/complications/genetics/pathology, *Alzheimer's disease, *bone density, *microtubule-associated protein, *serotonin, *tau proteins, *tauopathies, 2017, Age Factors, Alzheimer's disease, Alzheimer's Disease – Complications, Alzheimer's Disease – Pathology, Animal, Animal Studies, Animals, Biological, Body Composition, Body Composition/genetics, Body Weight, Body Weight/genetics, Bone Density – Physiology, Bone Density/*physiology, Bone Diseases – Etiology, Bone Diseases/*etiology, Brain Stem – Pathology, Dengler-Crish Christine M, Department of Pharmaceutical Sciences, Disease Models, Dorsal Raphe Nucleus/*pathology, Female, Inbred C57BL, Journal of Alzheimer's disease : JAD, Male, Mice, Models, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurons – Metabolism, Neurons – Pathology, Neurons/metabolism/pathology, Oxidoreductases – Metabolism, Phosphorylation, Serotonin – Metabolism, Serotonin/*metabolism, Smith Matthew A, tau Proteins/*genetics/metabolism, Tauopathies/complications/genetics, Transgenic, Tryptophan Hydroxylase/metabolism, Wilson Gina N
Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emer ging Role of Lipin-1.
Tags: 2017, alcoholic fatty liver disease, Alcoholic/*metabolism/pathology, AMP-Activated Protein Kinases/metabolism, Animals, Current molecular pharmacology, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Ethanol/chemistry/*metabolism, Fatty Liver, Humans, Inflammation, Inflammation/metabolism, Jogasuria Alvin, Lee Kwangwon, Lee Yoon-Kwang, Lipid Metabolism, Lipin-1, Liver/metabolism, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Phosphatidate Phosphatase/*metabolism, Sadana Prabodh, Signal Transduction, Sirtuin 1/metabolism, transcriptional regulators, Wu Jiashin, You Min, Zhang Yanqiao
Is the Public Service Loan Forgiveness program right for you?
Tags: 2017, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, debt, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Financial – United States, loan forgiveness, loan repayment, NEOMED College of Pharmacy, Notareschi Vincent, Program Evaluation, student loan, Training Support, Ulbrich Timothy R, United States
Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.
Tags: *Drug Delivery Systems, *Inflammation, *Microglia, *neuroprotection, *polymersomes, *simvastatin, 2017, Animals, Anti-Inflammatory Agents/*pharmacology, Department of Pharmaceutical Sciences, Inbred BALB C, Interleukin-6/antagonists & inhibitors/biosynthesis, Lactates/*administration & dosage, Manickavasagam Dharani, Mice, Microglia/*drug effects, NEOMED College of Pharmacy, Nitric Oxide/antagonists & inhibitors/biosynthesis, Novak Kimberly, Oyewumi Moses O, Polyethylene Glycols/*administration & dosage, Simvastatin/*administration & dosage/pharmacology, The AAPS journal, Tumor Necrosis Factor-alpha/antagonists & inhibitors/biosynthesis
Turnover of histones and histone variants in postnatal rat brain: effects of alcohol exposure.
Tags: *2H2O-labeling, *Brain, *Genetic Variation, *Histone, *Mass spectrometry, *Post-translational modifications, *Postnatal alcohol exposure, *Turnover, 2017, Acetylation, Animal, Animals, Cell Proliferation, Clinical epigenetics, Department of Pharmaceutical Sciences, Disease Models, DNA Damage, Epigenesis, Female, Fetal Alcohol Spectrum Disorders/genetics/*metabolism, Genetic, Histones/*genetics/*metabolism, Humans, Kasumov Takhar, Li Ling, NEOMED College of Pharmacy, Post-Translational, Pregnancy, Previs Stephen, Protein Processing, Proteomics/*methods, Rachdaoui Nadia, Rats, Sarkar Dipak, Sprague-Dawley, Willard Belinda
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Tags: *Alzheimers disease, *Immunity, *Inflammation, *Tauopathy, *TREM2, 2017, Allan Kevin, Animal, Animals, Bemiller Shane M, Crish Samuel D, Department of Pharmaceutical Sciences, Disease Models, Formica Shane V, Humans, Immunologic/*deficiency, Inbred C57BL, Kokiko-Cochran Olga N, Lamb Bruce T, Landreth Gary E, Lasagna-Reeves Cristian A, McCray Tyler J, Membrane Glycoproteins/*deficiency, Mice, Microglia/metabolism, Molecular neurodegeneration, NEOMED College of Pharmacy, Protein Kinases/*metabolism, Ransohoff Richard M, Receptors, Signal Transduction/physiology, tau Proteins/*metabolism, Tauopathies/metabolism/*pathology, Transgenic, Wilson Gina, Xu Guixiang
Patient Awareness and Expectations of Pharmacist Services During Hospital Stay.
Tags: *Anticipation, *Awareness, *Health Knowledge, 2017, 80 and over, Adolescent, Adult, Aged, Attitudes, Betka Eric M, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Health Services Accessibility, Hospital, Hospital/methods/*statistics & numerical data, Human, Humans, Inpatients, Inpatients/*psychology, Journal of pharmacy practice, King Philip K, Male, Marketing, Marketing/methods, Martin Steven J, Middle Aged, NEOMED College of Pharmacy, Patient Attitudes, patient awareness, Patient Education, patient expectations, Pharmacists/*statistics & numerical data, Pharmacy Service, pharmacy services, Practice, Pretest-Posttest Design, Professional Role, Professional-Patient Relations, Psychological, Social Marketing, Summated Rating Scaling, Surveys, Surveys and Questionnaires, United States, Young Adult
Impact of Tranexamic Acid in Total Knee and Total Hip Replacement.
Tags: 2017, Aged, Antifibrinolytic Agents/adverse effects/therapeutic use, Arthroplasty, Blood Transfusion, Blood Transfusion/statistics & numerical data, Boyle Jaclyn A, Case-Control Studies, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Hemoglobins – Analysis, Hemoglobins/metabolism, Hip, Hip/*methods, Human, Humans, Journal of pharmacy practice, Knee, Knee/*methods, Length of Stay – Evaluation, Length of Stay/statistics & numerical data, Male, NEOMED College of Pharmacy, Outcome Assessment, Replacement, Retrospective Design, Retrospective Studies, Soric Mate M, total hip replacement, total knee replacement, tranexamic acid, Tranexamic Acid – Administration and Dosage, Tranexamic Acid/adverse effects/*therapeutic use, Venous Thromboembolism – Risk Factors, Venous Thromboembolism/epidemiology
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the
Tags: *CYTOKINES, *ETHANOL, *FATTY LIVER, *Inflammation, *LEUKOCYTES, 2017, Adult, Alanine Transaminase/blood, Alcoholic/genetics/*metabolism/pathology, Alcoholism/*blood/complications, Animals, Aspartate Aminotransferases/blood, Bilirubin/blood, Binge Drinking/*blood/complications, Cai Yan, Cao Haixia, Case-Control Studies, Central Nervous System Depressants/administration & dosage, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Down-Regulation, Ethanol/administration & dosage, Female, Feng Dechun, Gao Bin, Gao Yanhang, Gao Yueqiu, Gut, He Yong, Humans, Inbred C57BL, Interleukin-6/genetics/metabolism, Li Man, Liangpunsakul Suthat, Liver Diseases, Male, Mice, MicroRNAs/*blood/*genetics, Middle Aged, NADPH Oxidases/genetics/metabolism, NEOMED College of Medicine, NEOMED College of Pharmacy, Neutrophils/*metabolism, Ramirez Teresa, Reactive Oxygen Species/metabolism, Ross Ruth A, Up-Regulation, Xu Ming-Jiang, Young Adult, Zhang Ping, Zhou Zhou
Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
Tags: 2017, Animals, Chen Ying, Daurio Natalie A, Department of Pharmaceutical Sciences, Drug Discovery/*methods, Erion Mark D, Humans, Isotope Labeling, Isotopes/chemistry, Johns Douglas G, Kasumov Takhar, Kelley David E, McLaren David G, Metabolic Flux Analysis/*methods, Milot Denise, NEOMED College of Pharmacy, Previs Stephen F, Roddy Thomas P, The Journal of pharmacology and experimental therapeutics, Wang Sheng-Ping, Water/chemistry/metabolism, Zhou Haihong
Pyrethroid Insecticides Directly Activate Microglia Through Interaction With Voltage-Gated Sodium Channels.
Tags: *deltamethrin, *intracellular sodium., *Microglia, *neurodegeneration, *Neuroinflammation, *permethrin, *pyrethroids, *tetrodotoxin, *tumor necrosis factor, *Voltage-gated sodium channels, 2017, Animals, Cell Line, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Hossain Muhammad M, Inbred C57BL, Insecticides/*toxicity, Ion Channel Gating/*drug effects, Liu Jason, Mice, Microglia/*drug effects/metabolism, NEOMED College of Pharmacy, Pyrethrins/*toxicity, Richardson Jason R, Sodium Channels/*drug effects, Toxicological sciences : an official journal of the Society of Toxicology, Transformed, Tumor Necrosis Factor-alpha/metabolism
MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.
Tags: *Aging, *Disease Models, *drug discovery, *mitochondrial dysfunction, *mitoNEET, 2017, ACS chemical neuroscience, Animal, Animals, Benkovic Stanley A, Brown Candice M, Corpus Striatum/*metabolism/*pathology, Crish Samuel D, Darvesh Altaf S, Department of Pharmaceutical Sciences, Geldenhuys Werner J, Inbred C57BL, Iron-Binding Proteins/genetics/*metabolism, Knockout, Lin Li, Male, Membrane Proteins/genetics/*metabolism, Mice, Mitochondria/*metabolism/*pathology, NEOMED College of Pharmacy, Parkinson Disease/*metabolism/pathology, Richardson Jason R, Sullivan Patrick G, Yonutas Heather M
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Tags: 1-Methyl-4-phenyl-1, 2, 2017, 3, 6-tetrahydropyridine/*administration & dosage, Alam Gelareh, Animals, Burchfield Shelbie L, Catecholamines/metabolism, Cell Count, Corpus Striatum/*drug effects/metabolism, Department of Pharmaceutical Sciences, Dopamine, Dopamine transporter, Dopaminergic Neurons/*drug effects/metabolism, Edler Melissa, Inbred C57BL, Male, Mice, MPTP, MPTP Poisoning, NEOMED College of Pharmacy, Neurotoxicology, Parkinsonian Disorders/*metabolism/*pathology, Richardson Jason R, Stereology, Substantia Nigra/*drug effects/metabolism, Tyrosine 3-Monooxygenase/*metabolism, Tyrosine hydroxylase, Vesicular monoamine transporter
Developmental pyrethroid exposure causes long-term decreases of neuronal sodium channel expression.
Tags: 2017, Animals, BDNF, Brain-Derived Neurotrophic Factor/metabolism, Cerebral Cortex/*drug effects/growth & development/metabolism, Corpus Striatum/*drug effects/growth & development/metabolism, Deltamethrin, Department of Pharmaceutical Sciences, Female, Inbred C57BL, Insecticides/*toxicity, Magby Jason P, Male, Messenger/metabolism, Mice, NEOMED College of Pharmacy, Neurodevelopmental, Neurons/*drug effects/metabolism, Neurotoxicology, Nitriles/*toxicity, Pregnancy, Prenatal Exposure Delayed Effects/*metabolism, Pyrethrins/*toxicity, Pyrethroid, Richardson Jason R, RNA, Sodium channel, Voltage-Gated Sodium Channels/*metabolism
Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.
Tags: 2017, Alam Gelerah, Animals, Astrocytes/immunology/pathology, Beier Eric E, Cell Death/physiology, Corpus Striatum/immunology/pathology, Cytokines/metabolism, Department of Pharmaceutical Sciences, Disease Progression, Dopaminergic Neurons/*immunology/pathology, Edler Melissa, Inbred C57BL, Inflammation/pathology/physiopathology, Lipopolysaccharides/*toxicity, Male, Messenger/metabolism, Mice, Microglia/*immunology/pathology, Neal Matthew, NEOMED College of Pharmacy, Nerve Degeneration/*immunology/pathology, Neurobiology of disease, Neurodegenerative Diseases/immunology/pathology, Neuroimmunomodulation/physiology, Random Allocation, Richardson Jason R, RNA, Time Factors, Wu Long-Jun
Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes.
Tags: *Ceruloplasmin, *Deamidation, *Heavy water metabolic labeling, *High resolution mass spectrometry, *Iron metabolism, *LC-MS/MS, *Non-enzymatic glycation, *Oxidative Stress, *Protein Processing, *Proteome dynamics, *Serotransferrin, *Type 2 diabetes mellitus, 2017, Adult, Amino Acid Sequence, Bena James, Case-Control Studies, Ceruloplasmin/genetics/*metabolism, Department of Pharmaceutical Sciences, Deuterium/metabolism, Diabetes Mellitus, Diabetic, Diet, Female, Free radical biology & medicine, Gene Expression Regulation, Glycated Hemoglobin A/genetics/metabolism, Glycosylation, Golizeh Makan, Humans, Ilchenko Serguei, Iron/*metabolism, Isotope Labeling, Kashyap Sangeeta R, Kasumov Takhar, Lee Kwangwon, Male, Middle Aged, NEOMED College of Pharmacy, Osme Abdullah, Oxidation-Reduction, Oxidative Stress, Post-Translational, Proteolysis, Sadygov Rovshan G, Transferrin/genetics/*metabolism, Type 2/diet therapy/genetics/*metabolism/pathology
Injury-induced gp130 cytokine signaling in peripheral ganglia is reduced in diabetes mellitus.
Tags: *Axon regeneration, *Axotomy, *Diabetes, *Neuropathy, *Peripheral nervous system, 2017, Animal, Animals, Antibiotics, Antineoplastic/toxicity, Blood Glucose/drug effects, Body Weight/drug effects, Crish Samuel D, Cytokine Receptor gp130/genetics/*metabolism, Cytokines/metabolism, DeFrancesco Alicia, Department of Pharmaceutical Sciences, Diabetes Mellitus, Disease Models, Experimental neurology, Experimental/chemically induced/complications/*pathology, Fasting/blood, Filous Angela R, Gene Expression Regulation/*physiology, Hyperalgesia/etiology, Hyperglycemia/etiology, Inbred C57BL, Lindborg Jane A, Male, Malhotra Nisha A, Mice, NEOMED College of Pharmacy, Nerve Degeneration/*etiology/pathology, Nerve Tissue Proteins/metabolism, Niemi Jon P, Pain Measurement, Signal Transduction/drug effects/*physiology, Streptozocin/toxicity, Superior Cervical Ganglion/drug effects/*metabolism, Sweating/drug effects, Wilson Gina N, Zhou Bowen, Zigmond Richard E
Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.
Tags: 2017, Animals, Cardiovascular Diseases/drug therapy/*enzymology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery Today, Geldenhuys Werner J, Humans, Lin Li, Lipoprotein Lipase/chemistry/*metabolism, Metabolic Diseases/drug therapy/*enzymology, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh
Toolkit for US colleges/schools of pharmacy to prepare learners for careers in academia.
Tags: *Academia, *Career, *Student preparation, *Training, 2017, Boyle Jaclyn A, Clifford Kalin M, Currents in pharmacy teaching & learning, Curriculum/trends, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dy-Boarman Eliza A, Education, Faculty, Haines Seena L, Humans, NEOMED College of Pharmacy, Peeters Michael J, Pharmacy/*education/organization & administration, Pharmacy/*methods/organization & administration, Pharmacy/*psychology, Students, Summa Maria A, Universities/organization & administration/trends, Willson Megan N, Workforce
Preparing students for residency interviews through a residency interview boot camp.
Tags: *Career Mobility, *Internship and Residency, *Interviewing skills, *Mock interview, *Residency training, 2017, Adult, Boyle Jaclyn A, Currents in pharmacy teaching & learning, Curriculum/trends, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Feedback, Female, Humans, interviews, Interviews as Topic/*methods/standards, Male, NEOMED College of Pharmacy, pharmacy residency, Pharmacy/*psychology, Pharmacy/methods, residency interviews, Students, Ulbrich Timothy R, Workforce
Identifying motivators and barriers to student completion of instructor evaluations: A multi-faceted, collaborative approach from four colleges of pharmacy.
Tags: *Attitude of Health Personnel, *Barriers, *Faculty, *Focus group, *Instructor evaluation, *Motivators, *Student, 2017, Adult, Backo Jennifer Lynn, Currents in pharmacy teaching & learning, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Educational Measurement/methods/*standards, Faculty/standards, Female, Humans, Male, McAuley James W, Metzger Anne H, Middle Aged, Motivation, NEOMED College of Pharmacy, Ohio, Pharmacy/*methods, Pharmacy/*psychology, Sobota Kristen Finley, Students, Surveys and Questionnaires, Ulbrich Timothy, Universities/organization & administration
Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.
Tags: *Diabetes, *High-fat diet, *Homology modeling, *Hyperlipidemia, *Lipoprotein lipase, *Liver cirrhosis, *Obesity, 2017, Animals, Benzeneacetamides/chemical synthesis/chemistry/*pharmacology, Bioorganic & medicinal chemistry letters, Caporoso Joel, Darvesh Altaf S, Department of Integrative Medical Sciences, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dose-Response Relationship, Drug, Geldenhuys Werner J, Imidazoles/chemical synthesis/chemistry/*pharmacology, Lee Yoon-Kwang, Leeper Thomas C, Lin Li, Lipoprotein Lipase/*metabolism, Mice, Molecular Docking Simulation, Molecular Structure, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Pharmacy, Sadana Prabodh, Structure-Activity Relationship
Mechanisms of Gene-Environment Interactions in Parkinson's Disease.
Tags: *Alpha-synuclein, *ATP13A2, *Gene-Environment Interaction, *Genetic Predisposition to Disease, *Manganese, *Paraquat, *Parkinson Disease, *Parkinson's disease, *Rotenone, 2017, Current environmental health reports, Department of Pharmaceutical Sciences, Environmental Exposure/*adverse effects, Fleming Sheila M, Herbicides/adverse effects, Humans, Insecticides/adverse effects, Mutation/genetics, NEOMED College of Pharmacy, Paraquat/adverse effects, Risk Factors, Rotenone/adverse effects