1
40
21
-
Text
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<a href="http://doi.org/10.1002/jac5.1119" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jac5.1119</a>
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Pages
321-321
Issue
3
Volume
2
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Title
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A need for a holistic residency application review process.
Publisher
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JACCP: Journal of the American College of Clinical Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-06
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Soric Mate M; Robinson Jennifer D; Ulbrich Timothy R
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<a href="http://doi.org/10.1002/jac5.1119" target="_blank" rel="noreferrer noopener">10.1002/jac5.1119</a>
2019
Department of Pharmacy Practice
JACCP: Journal of the American College of Clinical Pharmacy
NEOMED College of Pharmacy
Robinson Jennifer D
September 2019 Update
Soric Mate M
Ulbrich Timothy R
-
Text
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n/a
Pages
S74–S74
Volume
67
ISSN
0002-8614
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Title
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Adaption of Geriatric Education Model Across Sites: Does Group Size Matter?
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Journal of the American Geriatrics Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
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Geriatrics & Gerontology
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Drost J; Brown D K; Joan N; Sanders M; Fosnight S; Hazelett S; Kropp D
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n/a
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Description
An account of the resource
2019 Annual Scientific Meeting of the American-Geriatrics-Society (AGS)
2019
Brown D K
Department of Family & Community Medicine
Department of Pharmacy Practice
Drost J
Fosnight S
Geriatrics & Gerontology
Hazelett S
Joan N
Journal of the American Geriatrics Society
June 2019 Update
Kropp D
NEOMED College of Medicine
NEOMED College of Pharmacy
Sanders M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/YIC.0000000000000269" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/YIC.0000000000000269</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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Title
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Addressing clozapine under-prescribing and barriers to initiation: a psychiatrist, advanced practice provider, and trainee survey
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International Clinical Psychopharmacology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-05
Creator
An entity primarily responsible for making the resource
Leung Jonathan G; Cusimano Joseph; Gannon Jessica M; Milgrom Olga; Valcourt Stephanie C; Stoklosa Joseph B; Kemp Michael; Olsufka William; Vickery P Brittany; Nichols Stephanie D; Crouse Ericka L; Paxos Chris; Johnson Emily K; Palmer Brian A
Description
An account of the resource
Clozapine use has declined, despite its superior antipsychotic efficacy in treatment-resistant schizophrenia. Implications for clozapine underutilization include suboptimal treatment outcomes and increased hospitalizations. Many barriers preventing the use of clozapine have been described in the literature, including suboptimal knowledge and poor perceptions. The aim of this study was to assess psychiatry prescribers' perception and knowledge of clozapine. A survey was distributed to advanced practice providers, psychiatrists, and trainees (i.e. residents and fellows) at 10 medical centers within the US and Canada. The survey asked respondents about their perception of clozapine use and assessed their pharmacotherapeutic knowledge of clozapine. Two hundred eleven individual submitted completed surveys of a possible 1152; a response rate of 18.3%. There were no statistically significant differences between the advanced practice provider plus psychiatrist groups and the trainee group for most perception (eight of nine) and knowledge (eight of nine) questions. The knowledge questions with the lowest scores pertained to clozapine reinitiation and myocarditis. The majority of all respondents (144, 68.2%) felt that clozapine prescribing was a burden. Findings of this study support the need for continued clozapine education regardless of a prescriber's age/experience. Future studies to assess barriers to clozapine prescribing should extend beyond academic centers.
Identifier
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<a href="http://doi.org/10.1097/YIC.0000000000000269" target="_blank" rel="noreferrer noopener">10.1097/YIC.0000000000000269</a>
2019
Crouse Ericka L
Cusimano Joseph
Department of Pharmacy Practice
Gannon Jessica M
International Clinical Psychopharmacology
Johnson Emily K
June 2019 Update
Kemp Michael
Leung Jonathan G
Milgrom Olga
NEOMED College of Pharmacy
Nichols Stephanie D
Olsufka William
Palmer Brian A
Paxos Chris
Stoklosa Joseph B
Valcourt Stephanie C
Vickery P Brittany
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/jphp.13138" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/jphp.13138</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1421-1428
Issue
9
Volume
71
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Title
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AMPK‐SIRT1‐independent inhibition of ANGPTL3 gene expression is a potential lipid‐lowering mechanism of metformin.
Publisher
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Journal of Pharmacy & Pharmacology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-09
Subject
The topic of the resource
angiopoietin‐like 3; diabetes; dyslipidaemia; lipoprotein lipase; metformin
Creator
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Lin Li; Burke Jamie; Venkatesh Sahana; Sadana Prabodh
Description
An account of the resource
Objectives: Hypertriglyceridaemia enhances cardiovascular disease risk in patients with diabetes. Lipoprotein lipase (LPL) regulates plasma triglyceride levels by hydrolysing chylomicrons and very‐low‐density lipoprotein (VLDL). Metformin, an antidiabetic drug, improves plasma lipids including triglycerides. We examined metformin's regulation of angiopoietin‐like 3 (ANGPTL3), a liver‐derived secretory protein with LPL inhibitory property. Methods: Using HepG2 cells, a human hepatocyte cell line, the effects of metformin on ANGPTL3 gene and protein expression were determined. The role of AMPK‐SIRT1 pathway in metformin regulation of ANGPTL3 was determined using pharmacological, RNAi and reporter assays. Metformin regulation of ANGPTL3 expression was also examined in sodium palmitate‐induced insulin resistance. Key findings: Metformin and pharmacological activators of AMPK and SIRT1 inhibited the expression of ANGPTL3 in HepG2 cells. Pharmacological or RNAi‐based antagonism of AMPK or SIRT1 failed to affect metformin inhibition of ANGPTL3. AMPK‐SIRT1 activators and metformin exhibited distinct effects on the expression of ANGPTL3 gene luciferase reporter. Sodium palmitate‐induced insulin resistance in cells resulted in increased ANGPTL3 gene expression which was suppressed by pretreatment with metformin. Conclusions: Metformin inhibits ANGPTL3 expression in the liver in an AMPK‐SIRT1‐independent manner as a potential mechanism to regulate LPL and lower plasma lipids. [ABSTRACT FROM AUTHOR]
Identifier
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<a href="http://doi.org/10.1111/jphp.13138" target="_blank" rel="noreferrer noopener">10.1111/jphp.13138</a>
2019
angiopoietin‐like 3
Burke Jamie
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Diabetes
dyslipidaemia
Journal of Pharmacy & Pharmacology
Lin Li
Lipoprotein lipase
metformin
NEOMED College of Graduate Studies
NEOMED College of Pharmacy
Sadana Prabodh
September 2019 Update
Venkatesh Sahana
-
Text
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URL Address
<a class="doi" href="https://doi.org/10.1016/j.xjep.2019.03.007" target="_blank" title="Persistent link using digital object identifier" rel="noreferrer noopener">https://doi.org/10.1016/j.xjep.2019.03.007</a>
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Pages
114-118
Volume
15
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Title
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An interprofessional case study competition addressing community healthcare needs and the opioid crisis
Publisher
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Journal of Interprofessional Education & Practice
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-06
Creator
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DeBoth Kelle K; Stoddard-Dare Patricia; Bruce Susan; Niederriter Joan
Identifier
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<a class="doi" href="https://doi.org/10.1016/j.xjep.2019.03.007" target="_blank" title="Persistent link using digital object identifier" rel="noreferrer noopener">https://doi.org/10.1016/j.xjep.2019.03.007</a>
2019
Bruce Susan
DeBoth Kelle K
Department of Pharmacy Practice
Journal of Interprofessional Education & Practice
June 2019 Update
NEOMED College of Pharmacy
Niederriter Joan
Stoddard-Dare Patricia
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1021/acs.analchem.9b02757" target="_blank" rel="noreferrer noopener">http://doi.org/10.1021/acs.analchem.9b02757</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
14340-14351
Issue
22
Volume
91
ISSN
1520-6882
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<a href="http://ezproxy.neomed.idm.oclc.org/login?url=http://doi.org/10.1021/acs.analchem.9b02757" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1021/acs.analchem.9b02757</a>
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Title
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Calculation of the Protein Turnover Rate Using the Number of Incorporated 2H Atoms and Proteomics Analysis of a Single Labeled Sample
Publisher
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Analytical Chemistry
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-11-19
Creator
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Ilchenko Serguei; Haddad Andrew; Sadana Prabodh; Recchia Fabio A; Sadygov Rovshan G; Kasumov Takhar
Description
An account of the resource
Rate constant estimation with heavy water requires a long-term experiment with data collection at multiple time points (3-4 weeks for mitochondrial proteome dynamics in mice and much longer in other species). When tissue proteins are analyzed, this approach requires euthanizing animals at each time point or multiple tissue biopsies in humans. Although short-term protocols are available, they require knowledge of the maximum number of isotope labels (N) and accurate quantification of observed 2H-enrichment in the peptide. The high-resolution accurate mass spectrometers used for proteome dynamics studies are characterized by a systematic spectral error that compromises these measurements. To circumvent these issues, we developed a simple algorithm for the rate constant calculation based on a single labeled sample and comparable unlabeled (time 0) sample. The algorithm determines N for all proteogenic amino acids from a long-term experiment to calculate the predicted plateau 2H-labeling of peptides for a short-term protocol and estimates the rate constant based on the measured baseline and the predicted plateau 2H-labeling of peptides. The method was validated based on the rate constant estimation in a long-term experiment in mice and dogs. The improved 2 time-point method enables the rate constant calculation with less than 10% relative error compared to the bench-marked multi-point method in mice and dogs and allows us to detect diet-induced subtle changes in ApoAI turnover in mice. In conclusion, we have developed and validated a new algorithm for protein rate constant calculation based on 2-time point measurements that could also be applied to other biomolecules.
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<a href="http://doi.org/10.1021/acs.analchem.9b02757" target="_blank" rel="noreferrer noopener">10.1021/acs.analchem.9b02757</a>
PMID: 31638786
Format
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Journal Article
2019
Analytical Chemistry
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Haddad Andrew
Ilchenko Serguei
Journal Article
Kasumov Takhar
NEOMED College of Graduate Studies
NEOMED College of Pharmacy
November 2019 Update
Recchia Fabio A
Sadana Prabodh
Sadygov Rovshan G
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.amjcard.2019.07.006" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.amjcard.2019.07.006</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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Title
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Consensus Clinical Decision-Making Factors Driving Anticoagulation in Atrial Fibrillation
Publisher
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The American Journal of Cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-07
Creator
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King Philip K; Fosnight Susan M; Bishop Jeffrey R
Description
An account of the resource
Guideline-recommended anticoagulation is frequently omitted in high-risk patients with atrial fibrillation (AF) for reasons not fully understood, which may result in suboptimal care. A nationally representative, expert group of physicians (cardiology, neurology, and general medicine), and clinical pharmacists participated in a consensus-seeking, modified Delphi method to identify key clinical decision-making factors driving anticoagulant prescribing in real-world AF patients. Representing >2,500 anticoagulation-related patient encounters per month, 27 of 30 participants completed the study (90% overall response rate). In Round-1, experts rated their level of agreement with factors and suggested modifications or additional factors. Of 66 factors entering Round-1, 21 met and 4 partially met consensus, 41 did not meet consensus, and 7 were newly suggested. Of 32 factors advanced for scoring in Round-2, 16 met consensus criteria. In Round-3, experts were given the option to rescue up to 2 of the 16 nonconsensus factors from Round-2. Including a concomitant need for dual antiplatelet therapy, no factor was successfully rescued into consensus. The most important factors related to risk of infarction rather than bleeding risk or other patient-specific considerations. Among factors not independently addressed in current guidelines, these included baseline hematologic indicators of potential bleeding risk, previous bleeding episodes by specific type, other risk factors for bleeding, and adherence. In conclusion, when determining anticoagulation strategies in AF, there is a need for further research on the clinical implications of these emerging factors as well as the reasons behind divergent opinions toward nonconsensus factors.
Identifier
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<a href="http://doi.org/10.1016/j.amjcard.2019.07.006" target="_blank" rel="noreferrer noopener">10.1016/j.amjcard.2019.07.006</a>
2019
Bishop Jeffrey R
Department of Pharmacy Practice
Fosnight Susan M
King Philip K
NEOMED College of Pharmacy
September 2019 Update
The American journal of cardiology
-
Text
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URL Address
<a href="http://doi.org/10.1093/ajhp/zxy084" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/ajhp/zxy084</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S49-S54
Volume
76
Dublin Core
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Title
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effect of an interprofessional pain service on nonmalignant pain control.
Publisher
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American Journal of Health-System Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-06
Subject
The topic of the resource
chronic pain; chronic pain; DISCHARGE planning; HEALTH literacy; HEALTH occupations students; INTERDISCIPLINARY education; LENGTH of stay in hospitals; MEDICAL appointments & schedules; MEDICAL care; MEDICAL personnel & patient; MEDICAL protocols; MEDICAL records; MEDICAL referrals; MEDICALLY underserved persons; medication therapy management; MORPHINE; opioid; pain management; pain management; PAIN measurement; PATIENT education; PATIENT satisfaction; pharmacist; pharmacists; RETROSPECTIVE studies; SUBSTANCE abuse; SURVEYS; TELEPHONES; THERAPEUTIC use of narcotics
Creator
An entity primarily responsible for making the resource
Coffey Cory P; Ulbrich Timothy R; Baughman Kristin R; Awad Magdi H
Description
An account of the resource
Purpose The primary objective of this project was to evaluate an existing interprofessional, nonmalignant pain service by measuring the difference in patient pain scores (numeric rating scale-11) before and after a pharmacist-led pain education class and medication therapy management (MTM) visit. Secondary objectives included determining the percentage of pharmacist recommendations approved, patient satisfaction, and difference in immediate release (IR) and extended release (ER) opioid use before and after enrollment. Methods Baseline data were obtained from a retrospective chart review. Enrolled patients attended an educational pain class with the pharmacist. At the MTM visit with the pharmacist 3–14 days after the initial education class, the patient's pain score was assessed along with his/her medication use, and a care plan was developed and forwarded to the referring provider for implementation. Three months after the pain class and participation in the MTM visit, patients were contacted via telephone to complete a survey. The survey questions assessed patient satisfaction with the pain education program, their current pain score, and their knowledge of information covered during the pain class. Results Patients reported an average preenrollment pain score of 8.3/10 (n = 39) and a post-survey pain score of 5.6/10 (n = 39). The IR opioid use averaged 19.7 morphine equivalent daily dose (MEDD) at enrollment and decreased by 40% to 11.8 MEDD. The provider approval rate of the pharmacist-recommended interventions ranged from 80% to 92%, depending on the predesignated disease state category. Conclusion An interprofessional, nonmalignant-pain service including a pharmacist-led class resulted in a decrease in average pain scores and MEDD in an underserved population. [ABSTRACT FROM AUTHOR]
Identifier
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<a href="http://doi.org/10.1093/ajhp/zxy084" target="_blank" rel="noreferrer noopener">10.1093/ajhp/zxy084</a>
2019
American Journal of Health-System Pharmacy
Awad Magdi H
Baughman Kristin R
Chronic pain
Coffey Cory P
Department of Family & Community Medicine
Department of Pharmacy Practice
DISCHARGE planning
HEALTH literacy
HEALTH occupations students
INTERDISCIPLINARY education
June 2019 Update
LENGTH of stay in hospitals
MEDICAL appointments & schedules
Medical care
MEDICAL personnel & patient
MEDICAL protocols
Medical Records
MEDICAL referrals
MEDICALLY underserved persons
Medication Therapy Management
MORPHINE
NEOMED College of Medicine
NEOMED College of Pharmacy
Opioid
Pain Management
Pain Measurement
Patient Education
Patient Satisfaction
pharmacist
Pharmacists
Retrospective Studies
Substance Abuse
Surveys
TELEPHONES
THERAPEUTIC use of narcotics
Ulbrich Timothy R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/phar.2269" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/phar.2269</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
724-729
Issue
6
Volume
39
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Title
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Efficacy of Tramadol for Pain Management in Patients Receiving Strong Cytochrome P450 2D6 Inhibitors
Publisher
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Pharmacotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-06
Subject
The topic of the resource
CYP2D6; cytochrome P450; drug interaction; pain control; tramadol
Creator
An entity primarily responsible for making the resource
Frost Derek A; Soric Mate M; Kaiser Ricky; Neugebauer Rachel E
Description
An account of the resource
STUDY OBJECTIVE: Tramadol is metabolized by cytochrome P450 (CYP) 2D6 to form an active metabolite that exhibits its analgesic effect. Medications that inhibit this enzyme are used often in practice, yet the clinical impact of this interaction on the analgesic effects of tramadol has yet to be fully described. The objective was to determine whether a clinically relevant decrease in pain control is observed in patients taking scheduled tramadol concomitantly with a strong CYP2D6 inhibitor. DESIGN: Retrospective cohort study. SETTING: Large health care system. PATIENTS: One hundred fifty-two adult inpatients who received scheduled tramadol for at least 24 hours with (76 patients) or without (76 patients) a strong CYP2D6 inhibitor between January 1, 2012, and February 28, 2017, were included in the analysis. Patients hospitalized for opioid use disorder or those receiving substandard dosing of tramadol were excluded. MEASUREMENTS AND MAIN RESULTS: The primary outcome was mean breakthrough opiate consumption in the presence and absence of CYP2D6 inhibitors. Secondary outcomes included mean pain scores, length of hospital stay, tramadol discontinuation rates, and prespecified subgroup analyses based on patient sex, race, and specific CYP2D6 inhibitor administered. Patients receiving concurrent CYP2D6 inhibitors required significantly more breakthrough morphine milligram equivalents per day compared with patients receiving scheduled tramadol without CYP2D6 inhibitors (geometric mean ± SD 18.2 ± 6.3 vs 5.7 ± 6.7 mg morphine milligram equivalents, p<0.001). No significant differences existed between cohorts for mean pain score, length of hospital stay, or tramadol discontinuation rate. CONCLUSION: This study demonstrated a clinically relevant decrease in the efficacy of tramadol when used for pain control in patients receiving a strong CYP2D6 inhibitor. These results should encourage clinicians to review medication lists for this interaction and adjust regimens accordingly to ensure adequate pain control.
Identifier
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<a href="http://doi.org/10.1002/phar.2269" target="_blank" rel="noreferrer noopener">10.1002/phar.2269</a>
2019
CYP2D6
cytochrome P450
Department of Pharmacy Practice
drug interaction
Frost Derek A
June 2019 Update
Kaiser Ricky
NEOMED College of Pharmacy
Neugebauer Rachel E
pain control
Pharmacotherapy
Soric Mate M
tramadol
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/ajhp/zxz174</a>
Pages
1492-1510
Issue
19
Volume
76
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Title
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Enteral and parenteral nutrition considerations in pediatric patients
Publisher
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American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-09
Subject
The topic of the resource
compounding; enteral; neonatal; nutrition; parenteral; pediatric; stability
October 2019 Update
Creator
An entity primarily responsible for making the resource
Cober Mary Petrea; Gura Kathleen M
Description
An account of the resource
PURPOSE: Current clinical practice guidelines on management of enteral nutrition (EN) and parenteral nutrition (PN) in pediatric patients are reviewed. SUMMARY: The provision of EN and PN in pediatric patients poses many unique considerations and challenges. Although indications for use of EN and PN are similar in adult and pediatric populations, recommended EN and PN practices differ for pediatric versus adult patients in areas such as selection of EN and PN formulations, timing of EN and PN initiation, advancement of nutrition support, and EN and PN goals. Additionally, provision of EN and PN to pediatric patients poses unique compounding and medication administration challenges. This article provides a review of current EN and PN best practices and special nutrition considerations for neonates, infants, and other pediatric patients. CONCLUSION: The provision of EN and PN to pediatric patients presents many unique challenges. It is important for pharmacists to keep current with pediatric- and neonatal-specific guidelines on nutritional management of various disease states, as well as strategies to address compounding and medication administration challenges, in order to optimize EN and PN outcomes.
Identifier
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<a href="http://doi.org/10.1093/ajhp/zxz174" target="_blank" rel="noreferrer noopener">10.1093/ajhp/zxz174</a>
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2019
American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists
Cober Mary Petrea
compounding
Department of Pharmacy Practice
enteral
Gura Kathleen M
NEOMED College of Pharmacy
Neonatal
nutrition
October 2019 Update
Parenteral
Pediatric
Stability
-
Text
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URL Address
<a href="http://doi.org/10.9740/mhc.2019.03.076" target="_blank" rel="noreferrer noopener">http://doi.org/10.9740/mhc.2019.03.076</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
76-81
Issue
2
Volume
9
NEOMED College
NEOMED College of Pharmacy; NEOMED College of Medicine
NEOMED Department
Department of Pharmacy Practice; Department of Psychiatry
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Title
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Evaluation of dextromethorphan with select antidepressant therapy for the treatment of depression in the acute care psychiatric setting.
Publisher
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The mental health clinician
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-03
Subject
The topic of the resource
depression; NMDA; fluoxetine; bupropion; CYP2D6 inhibitor; dextromethorphan; paroxetine
Creator
An entity primarily responsible for making the resource
Nofziger Jill L; Paxos Chris; Emshoff Jessica; Mullen Chanda
Description
An account of the resource
Introduction: Dextromethorphan (DXM), an N-methyl-D-aspartate receptor antagonist, may have ketamine-like antidepressant effects. Dextromethorphan is extensively metabolized via cytochrome P450 (CYP) 2D6, and its half-life in extensive metabolizers is 2 to 4 hours. The purpose of this study was to evaluate the effects of DXM in combination with a moderate-to-strong CYP2D6 inhibitor antidepressant on depression in an acute care psychiatric setting. Methods: This was a single-center, retrospective chart review of adult patients with a depressive disorder diagnosis. Patients who received select antidepressant therapy with or without scheduled DXM were included. The primary outcome was the difference in time to improvement of depressive symptoms, which was an average composite of physician documentation, nurse documentation, and first time to 24 hours without as-needed anxiolytics or antipsychotics. The study group consisted of patients who received DXM with select antidepressant therapy, whereas the control group included those who received only select antidepressant therapy. Results: A total of 40 patients were included. The median time to clinical improvement was 3.00 days and 2.83 days for the study group and control group, respectively (P = .986). The incidence of perceptual disturbances and delusions was higher in the study group as compared with the control group (55% and 35% vs 30% and 25%, respectively). Discussion: Dextromethorphan was not associated with a rapid antidepressant effect. The commonly used dose of 30 mg daily may have been too low to have an effect; additionally, the most frequently utilized select antidepressant, bupropion, has moderately less CYP2D6 inhibition than fluoxetine and paroxetine.
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<a href="http://doi.org/10.9740/mhc.2019.03.076" target="_blank" rel="noreferrer noopener">10.9740/mhc.2019.03.076</a>
2019
bupropion
CYP2D6 inhibitor
Department of Pharmacy Practice
Department of Psychiatry
Depression
dextromethorphan
Emshoff Jessica
fluoxetine
Mullen Chanda
NEOMED College of Medicine
NEOMED College of Pharmacy
NMDA
Nofziger Jill L
paroxetine
Paxos Chris
The mental health clinician
-
Text
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URL Address
<a href="http://doi.org/10.1002/jac5.1076" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jac5.1076</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
177-180
Issue
2
Volume
2
Dublin Core
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Title
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Grade point average is an inappropriate measure of a residency candidate's knowledge and skills.
Publisher
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JACCP: Journal of the American College of Clinical Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
The topic of the resource
Education; screening; students
Creator
An entity primarily responsible for making the resource
Soric Mate M; Robinson Jennifer D; Ulbrich Timothy R
Description
An account of the resource
Accreditation standards set forth by the American Society of Health‐System Pharmacists note that postgraduate year one programs should have a formal process in place to screen candidates based upon predetermined criteria to ensure applicants have the appropriate qualifications to complete residency training. This standard encourages programs to have a set of consistent criteria and an objective approach to evaluate each applicant. As a result, many programs rely heavily on accessible metrics, such as grade point average (GPA), to quickly compare candidates. The GPA has many flaws that, if utilized by residency programs, could result in screening out highly qualified candidates early in the application review process who possess the skills that residency program directors covet, such as work ethic, passion, adaptability, leadership, research experience, communication skills, professionalism, cultural competency, and personality fit. To identify qualified candidates for postgraduate residency training, the application review process must be reexamined to promote a more holistic approach, going beyond the student's ability in the classroom. Further discussion is needed regarding the pros and cons of utilization of standardized and consistent assessments of residency applicants' knowledge, skills, behaviors, and attitudes to complete a holistic review of candidates as discussed in this article. Further research is needed to identify the factors defining a successful resident and tools to predict those factors. [ABSTRACT FROM AUTHOR]
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<a href="http://doi.org/10.1002/jac5.1076" target="_blank" rel="noreferrer noopener">10.1002/jac5.1076</a>
2019
Department of Pharmacy Practice
Education
JACCP: Journal of the American College of Clinical Pharmacy
June 2019 Update
NEOMED College of Pharmacy
Robinson Jennifer D
screening
Soric Mate M
Students
Ulbrich Timothy R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/eurheartj/ehz748.0565" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/eurheartj/ehz748.0565</a>
Pages
1108-1108
Volume
40
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Update Year & Number
March 2020 Update
NEOMED College
NEOMED College of Medicine; NEOMED College of Pharmacy
NEOMED Department
Department of Internal Medicine; Department of Pharmacy Practice
Affiliated Hospital
Mercy Health St Elizabeth Youngstown Hospital
Dublin Core
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Title
A name given to the resource
Impact of cardiac MRI imaging on detection rates of myocarditis
Publisher
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European Heart Journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-10
Creator
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Morgenstern A; Mikolich B; Morgenstern D; Mikolich J R
Identifier
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<a href="http://doi.org/10.1093/eurheartj/ehz748.0565" target="_blank" rel="noreferrer noopener">10.1093/eurheartj/ehz748.0565</a>
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Journal Article
2019
Cleveland Clinic Avon Hospital
Department of Internal Medicine
Department of Pharmacy Practice
European Heart Journal
Mercy Health St Elizabeth Youngstown Hospital
Mikolich B
Mikolich J R
Morgenstern A
Morgenstern D
NEOMED College of Medicine
NEOMED College of Pharmacy
-
Text
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URL Address
<a href="http://doi.org/10.1111/jgs.15898" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/jgs.15898</a>
Pages
S71–S71
Volume
67
ISSN
0002-8614
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Interprofessional Education for Team-Based Geriatric Care
Publisher
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Journal of the American Geriatrics Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
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Geriatrics & Gerontology
Creator
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Brown D K; Drost J; Fosnight S; Morgan A; Hazelett S
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<a href="http://doi.org/10.1111/jgs.15898" target="_blank" rel="noreferrer noopener">10.1111/jgs.15898</a>
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Description
An account of the resource
Presentation A161 at the American Geriatrics Society 2019 Annual Meeting
2019
Brown D K
Department of Family & Community Medicine
Department of Pharmacy Practice
Drost J
Fosnight S
Geriatrics & Gerontology
Hazelett S
Journal of the American Geriatrics Society
June 2019 Update
Morgan A
NEOMED College of Medicine
NEOMED College of Pharmacy
-
Text
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URL Address
<a href="http://doi.org/10.1177/0897190019865147" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/0897190019865147</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
897190019865147-897190019865147
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Title
A name given to the resource
National Trends in Statin Medication Prescribing in Patients With a History of Stroke or Transient Ischemic Attack
Publisher
An entity responsible for making the resource available
Journal of Pharmacy Practice
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-07
Subject
The topic of the resource
statin; stroke; transient ischemic attack
Creator
An entity primarily responsible for making the resource
Snyder Brittany M; Soric Mate M
Description
An account of the resource
BACKGROUND: Guidelines support statin therapy post-stroke or transient ischemic attack (TIA); however, previously reported utilization rates are suboptimal. OBJECTIVE: This study investigates the incidence of statin usage in patients with a documented stroke or TIA while identifying predictors of statin use. METHODS: A retrospective, cross-sectional study utilizing data from the National Ambulatory Medical Care Survey. RESULTS: A total of 2963 unweighted visits were included in the analysis, representing a total of 52 645 000 office visits when weighted. Statin therapy was initiated or continued in 35.7% (95% confidence interval [CI]: 32.4-39.0%) of office visits. Upon multivariate analysis, positive predictors of statin therapy included a diagnosis of hyperlipidemia (odds ratio [OR]: 3.60; 95% CI: 2.40-5.41), angiotensin-converting enzyme inhibitor (ACE-I) therapy (OR: 2.52; 95% CI: 1.69-3.76), aspirin therapy (OR: 2.02; 95% CI: 1.40-2.93), and clopidogrel therapy (OR: 2.60; 95% CI: 1.69-4.02). Negative predictors of statin therapy included office visits with neurologists when compared to visits with primary care practitioners (OR: 0.55; 95% CI: 0.33-0.90) and office visits in rural areas when compared to office visits in urban areas (OR: 0.64; 95% CI: 0.41-0.99). CONCLUSION: Various factors impact statin therapy use with overall utilization being suboptimal, highlighting an opportunity for medication optimization.
Identifier
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<a href="http://doi.org/10.1177/0897190019865147" target="_blank" rel="noreferrer noopener">10.1177/0897190019865147</a>
2019
Department of Pharmacy Practice
Journal of pharmacy practice
NEOMED College of Pharmacy
September 2019 Update
Snyder Brittany M
Soric Mate M
statin
stroke
transient ischemic attack
-
Text
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URL Address
<a href="http://doi.org/10.5888/pcd16.190163" target="_blank" rel="noreferrer noopener">http://doi.org/10.5888/pcd16.190163</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
E153
Volume
16
ISSN
1545-1151
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<a href="http://ezproxy.neomed.idm.oclc.org/login?url=http://doi.org/10.5888/pcd16.190163" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.5888/pcd16.190163</a>
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Update Year & Number
January 2020 Update
NEOMED College
NEOMED College of Pharmacy
NEOMED Department
Department of Pharmacy Practice
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Title
A name given to the resource
Pharmacists in Federally Qualified Health Centers: Models of Care to Improve Chronic Disease
Publisher
An entity responsible for making the resource available
Preventing Chronic Disease
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-11-21
Creator
An entity primarily responsible for making the resource
Rodis Jennifer L; Capesius Traci R; Rainey Julie T; Awad Magdi H; Fox Carrie Hornbeck
Description
An account of the resource
INTRODUCTION: Pharmacists are underused in the care of chronic disease. The primary objectives of this project were to 1) describe the factors that influence initiation of and sustainability for pharmacist-provided medication therapy management (MTM) in federally qualified health centers (FQHCs), with secondary objectives to report the number of patients receiving MTM by a pharmacist who achieve 2) hemoglobin A1c (HbA1c) control (≤9%) and 3) blood pressure control (<140/90 mm Hg). METHODS: We evaluated MTM provided by pharmacists in 10 FQHCs in Ohio through qualitative thematic analysis of semi-structured interviews with pharmacists and FQHC leadership and aggregate reporting of clinical markers. RESULTS: Facilitators of MTM included relationship building with clinicians, staff, and patients; regular verbal or electronic communication with care team members; and alignment with quality goals. Common MTM model elements included MTM provided distinct from dispensing medications, clinician referrals, and electronic health record access. Financial compensation strategies were inadequate and varied; they included 340B revenue, incident-to billing, grants, and shared positions with academic institutions. Of 1,692 enrolled patients, 60% (n = 693 of 1,153) achieved HbA1c ≤9%, and 79% (n = 758 of 959) achieved blood pressure <140/90 mm Hg. CONCLUSION: Through this statewide collaborative, access for patients in FQHCs to MTM by pharmacists increased. The factors we identified that facilitate MTM practice models can be used to enhance the models to achieve clinical goals. Collaboration among clinic staff and community partners can improve models of care and improve chronic disease outcomes.
Identifier
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<a href="http://doi.org/10.5888/pcd16.190163" target="_blank" rel="noreferrer noopener">10.5888/pcd16.190163</a>
PMID: 31753083 PMCID: PMC6880917
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2019
Awad Magdi H
Capesius Traci R
Department of Pharmacy Practice
Fox Carrie Hornbeck
January 2020 Update
Journal Article
NEOMED College of Pharmacy
Preventing Chronic Disease
Rainey Julie T
Rodis Jennifer L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jac5.1041" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jac5.1041</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
167-176
Issue
2
Volume
2
Dublin Core
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Title
A name given to the resource
Pharmacists' role in glycemic management in the inpatient setting: An opinion of the endocrine and metabolism practice and research network of the American College of Clinical Pharmacy.
Publisher
An entity responsible for making the resource available
JACCP: Journal of the American College of Clinical Pharmacy
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
The topic of the resource
Diabetes Mellitus; hyperglycemia; hypoglycemia; inpatients; pharmacists
Creator
An entity primarily responsible for making the resource
Donihi Amy C; Moorman John M; Abla Alicia; Hanania Raja; Carneal Dustin; MacMaster Heidemarie Windham
Description
An account of the resource
The objective of this opinion paper was to identify and describe the role of pharmacists in ensuring safe and optimal management of patients with glycemic excursions in the inpatient setting. The role of the pharmacist includes involvement in admission medication history and reconciliation, formulary management of glucose‐lowering medications and devices, individual patient medication management, discharge transition of care, and interprofessional collaboration with other health care providers. Recommendations are based on review of published guidelines and literature focusing on the management of patients with hypo‐ and hyperglycemia in the hospital as well as during the time of transition to and from the inpatient setting. [ABSTRACT FROM AUTHOR]
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jac5.1041" target="_blank" rel="noreferrer noopener">10.1002/jac5.1041</a>
2019
Abla Alicia
Carneal Dustin
Department of Pharmacy Practice
Diabetes Mellitus
Donihi Amy C
Hanania Raja
hyperglycemia
hypoglycemia
Inpatients
JACCP: Journal of the American College of Clinical Pharmacy
June 2019 Update
MacMaster Heidemarie Windham
Moorman John M
NEOMED College of Pharmacy
Pharmacists
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4088/JCP.18m12588" target="_blank" rel="noreferrer noopener">http://doi.org/10.4088/JCP.18m12588</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Issue
4
Volume
80
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Title
A name given to the resource
Prevalence and Predictors of Benzodiazepine Monotherapy in Patients With Depression: A National Cross-Sectional Study
Publisher
An entity responsible for making the resource available
The Journal of Clinical Psychiatry
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-05
Creator
An entity primarily responsible for making the resource
Soric Mate M; Paxos Chris; Dugan Sara E; Fosnight Susan M; Turosky Jodie Z; Sadana Prabodh; Emshoff Jessica B; Everly Lukas; Snyder Brittany M; Mistry Bhavin K; Bhat Shubha; Unruh Amy E; Safi Ismail M
Description
An account of the resource
OBJECTIVE: Depression guidelines discourage benzodiazepine monotherapy and limit use to short-term adjunctive therapy with antidepressants; however, patients with depression continue to receive benzodiazepine monotherapy. The prevalence and predictors of this prescribing pattern have not been described previously and are warranted to assist clinicians in identifying patients at highest risk of receiving benzodiazepine monotherapy. METHODS: A national, cross-sectional analysis of the National Ambulatory Medical Care Survey from 2012 to 2015 was performed for adults treated for depression. Depression was identified using a survey item specifically assessing the presence of depression. Office visits involving patients with bipolar disorder, schizoaffective disorder, or pregnancy were identified by ICD-9 code or specific survey item and were excluded. The primary endpoint was benzodiazepine monotherapy prescribing rate defined as initiation or continuation of a benzodiazepine in the absence of any antidepressant agent. A multivariate logistic regression model was created to identify variables associated with benzodiazepine monotherapy. RESULTS: In total, 9,426 unweighted visits were eligible for inclusion. Benzodiazepine monotherapy was identified in 9.3% of patients treated for depression (95% CI, 8.2%-10.6%). Predictors of benzodiazepine monotherapy included age of 45-64 years (OR = 1.39; 95% CI, 1.01-1.91), epilepsy-related office visit (OR = 5.34; 95% CI, 1.39-20.44), anxiety-related office visit (OR = 1.67; 95% CI, 1.23-2.27), underlying pulmonary disease (OR = 1.43; 95% CI, 1.09-1.87), and concomitant opiate prescribing (OR = 2.86; 95% CI, 2.01-4.06). Psychiatrists were less likely to prescribe benzodiazepine monotherapy than were other providers (OR = 0.42; 95% CI, 0.29-0.61). CONCLUSIONS: Benzodiazepine monotherapy is utilized in nearly 1 in 10 patients treated for depression. Adults aged 45 to 65 years, patients prescribed opioids, patients seen by primary care providers, and those with underlying anxiety, epilepsy, or pulmonary disorders are at highest risk.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.4088/JCP.18m12588" target="_blank" rel="noreferrer noopener">10.4088/JCP.18m12588</a>
2019
Bhat Shubha
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Dugan Sara E
Emshoff Jessica B
Everly Lukas
Fosnight Susan M
June 2019 Update
Mistry Bhavin K
NEOMED College of Graduate Studies
NEOMED College of Medicine
NEOMED College of Pharmacy
Paxos Chris
Sadana Prabodh
Safi Ismail M
Snyder Brittany M
Soric Mate M
The Journal of clinical psychiatry
Turosky Jodie Z
Unruh Amy E
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1093/ajhp/zxy084" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/ajhp/zxy084</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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Title
A name given to the resource
The effect of an interprofessional pain service on nonmalignant pain control.
Publisher
An entity responsible for making the resource available
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-03
Subject
The topic of the resource
chronic pain; pain management; pharmacist; medication therapy management; opioid
Creator
An entity primarily responsible for making the resource
Coffey Cory P; Ulbrich Timothy R; Baughman Kristin R; Awad Magdi H
Description
An account of the resource
PURPOSE: The primary objective of this project is to evaluate an existing interprofessional, nonmalignant pain service by measuring the difference in patient pain scores (numeric rating scale-11) before and after a pharmacist-led pain education class and medication therapy management (MTM) visit. Secondary objectives include determining the percentage of pharmacist recommendations approved, patient satisfaction, and difference in immediate release (IR) and extended release (ER) opioid use before and after enrollment. METHODS: Baseline data was obtained from a retrospective chart review. Enrolled patients attended an educational pain class with the pharmacist. At the MTM visit with the pharmacist 3-14 days after the initial education class, the patient's pain score was assessed along with his/her medication use and a care plan was developed and forwarded to the referring provider for implementation. Three months after the pain class and participation in the MTM visit, patients were contacted via phone to complete a survey. The survey questions assess patient satisfaction with the pain education program, their current pain score, and their knowledge of information covered during the pain class. RESULTS: Patients reported an average pre-enrollment pain score of 8.3/10 (n = 39) and a post-survey pain score of 5.6/10 (n = 39). The IR opioid use averaged 19.7 morphine equivalent daily dose (MEDD) at enrollment and decreased by 40% to 11.8 MEDD. The provider approval rate of the pharmacist recommended interventions ranges from 80%-92% depending on the pre designated disease state category. CONCLUSION: An interprofessional, nonmalignant pain service including a pharmacist-led class resulted in a decrease in average pain scores and MEDD in an underserved population.
Identifier
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<a href="http://doi.org/10.1093/ajhp/zxy084" target="_blank" rel="noreferrer noopener">10.1093/ajhp/zxy084</a>
2019
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Awad Magdi H
Baughman Kristin R
Chronic pain
Coffey Cory P
Department of Family & Community Medicine
Department of Pharmacy Practice
Medication Therapy Management
NEOMED College of Medicine
NEOMED College of Pharmacy
Opioid
Pain Management
pharmacist
Ulbrich Timothy R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/8755122518818826" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/8755122518818826</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
56-63
Issue
2
Volume
35
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Effect of Pharmacy-Led, Small-Group Academic Detailing on Prescribing Patterns in an Ambulatory Care Clinic
Publisher
An entity responsible for making the resource available
Journal of Pharmacy Technology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
The topic of the resource
medical education; clinical; medications; pharmacy; interventions; Pharmacology & Pharmacy; impact; academic detailing; ambulatory care; community practice; prescribing patterns; prior authorization
Creator
An entity primarily responsible for making the resource
Awad M H; Ulbrich T R; Furdich K M; Schneider S R; Gothard M D
Description
An account of the resource
Background: While academic detailing seems to be the most promising intervention to improve prescribing patterns, implementation could be challenging for small community practices. Objective: A pharmacy-led, interactive, and tailored small-group academic detailing in a federally qualified health center is described. The primary objective of the study was to determine if the small-group academic detailing improved the prescribing patterns of the medical providers for select disease states: type 2 diabetes mellitus (T2DM), hyperlipidemia (HLD), and essential hypertension (HTN). Methods: Prescribing patterns in a federally qualified health center were examined in relation to small-group academic detailing sessions from April 2010 to March 2015. The markers for improvement were the increase in utilizing metformin and statins in patients diagnosed with T2DM and HLD, respectively, and the reduction of beta-blocker use in patients diagnosed with essential HTN. Changes in prescribing patterns were evaluated using Pearson's chi(2) and Fisher's exact tests. Results: The average number of active, adult patients with T2DM, HLD, and essential HTN was 839, 1768, and 2547, respectively. Utilization of metformin in T2DM increased from 5.5% at baseline to 37.7%, statin utilization in HLD increased from 77.1% to 86.9%, and beta-blocker use in HTN decreased from 17.9% to 13.8% (P < .005). Conclusions: A pharmacy-led, small-group academic detailing program improved and maintained appropriate prescribing patterns in an underserved community practice. This study serves as a successful pilot emphasizing the pharmacist's role as an educator and a resource to medical providers regarding appropriate medication use.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/8755122518818826" target="_blank" rel="noreferrer noopener">10.1177/8755122518818826</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2019
academic detailing
Ambulatory Care
Awad M H
Clinical
community practice
Department of Pharmacy Practice
Furdich K M
Gothard M D
impact
interventions
Journal Article or Conference Abstract Publication
Journal of Pharmacy Technology
Medical education
medications
NEOMED College of Pharmacy
Pharmacology & Pharmacy
Pharmacy
Prescribing Patterns
prior authorization
Schneider S R
Ulbrich T R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/8755122518818826" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/8755122518818826</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
56-63
Issue
2
Volume
35
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Effect of Pharmacy-Led, Small-Group Academic Detailing on Prescribing Patterns in an Ambulatory Care Clinic.
Publisher
An entity responsible for making the resource available
Journal of Pharmacy Technology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-04
Subject
The topic of the resource
Adrenergic Beta-Antagonists -- Therapeutic Use; Adult; Ambulatory Care Facilities; Chi Square Test; Descriptive Statistics; Diabetes Mellitus; Education; Essential Hypertension -- Drug Therapy; Fisher's Exact Test; Human; Hyperlipidemia -- Drug Therapy; Medically Underserved Area; Metformin -- Therapeutic Use; Non-Traditional; Outcomes of Education; Pharmacy Service; Physicians -- Education; Prescribing Patterns -- Education; Statins -- Therapeutic Use; Type 2 -- Drug Therapy
Creator
An entity primarily responsible for making the resource
Awad Magdi H; Ulbrich Timothy R; Furdich Kenneth M; Schneider Stacy R; Gothard M David
Description
An account of the resource
Background: While academic detailing seems to be the most promising intervention to improve prescribing patterns, implementation could be challenging for small community practices. Objective: A pharmacy-led, interactive, and tailored small-group academic detailing in a federally qualified health center is described. The primary objective of the study was to determine if the small-group academic detailing improved the prescribing patterns of the medical providers for select disease states: type 2 diabetes mellitus (T2DM), hyperlipidemia (HLD), and essential hypertension (HTN). Methods: Prescribing patterns in a federally qualified health center were examined in relation to small-group academic detailing sessions from April 2010 to March 2015. The markers for improvement were the increase in utilizing metformin and statins in patients diagnosed with T2DM and HLD, respectively, and the reduction of β-blocker use in patients diagnosed with essential HTN. Changes in prescribing patterns were evaluated using Pearson's χ2 and Fisher's exact tests. Results: The average number of active, adult patients with T2DM, HLD, and essential HTN was 839, 1768, and 2547, respectively. Utilization of metformin in T2DM increased from 5.5% at baseline to 37.7%, statin utilization in HLD increased from 77.1% to 86.9%, and β-blocker use in HTN decreased from 17.9% to 13.8% (P < .005). Conclusions: A pharmacy-led, small-group academic detailing program improved and maintained appropriate prescribing patterns in an underserved community practice. This study serves as a successful pilot emphasizing the pharmacist's role as an educator and a resource to medical providers regarding appropriate medication use.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/8755122518818826" target="_blank" rel="noreferrer noopener">10.1177/8755122518818826</a>
2019
Adrenergic Beta-Antagonists -- Therapeutic Use
Adult
Ambulatory Care Facilities
Awad Magdi H
Chi Square Test
Department of Pharmacy Practice
Descriptive Statistics
Diabetes Mellitus
Education
Essential Hypertension -- Drug Therapy
Fisher's Exact Test
Furdich Kenneth M
Gothard M David
Human
Hyperlipidemia -- Drug Therapy
Journal of Pharmacy Technology
June 2019 Update
Medically Underserved Area
Metformin -- Therapeutic Use
NEOMED College of Pharmacy
Non-Traditional
Outcomes of Education
Pharmacy Service
Physicians -- Education
Prescribing Patterns -- Education
Schneider Stacy R
Statins -- Therapeutic Use
Type 2 -- Drug Therapy
Ulbrich Timothy R