Browse Items (4 total)
- Tags: *Alpha-synuclein
The effect of manganese exposure in Atp13a2-deficient mice.
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Parkinson's disease, *Sensorimotor function, 2018, Adenosine Triphosphatases/genetics/*metabolism, Aga Diana S, alpha-Synuclein/metabolism, Animal, Animals, Behavior, Brain/*drug effects/*metabolism, Department of Pharmaceutical Sciences, Ekhator Osunde R, Female, Fleming Sheila M, Holden John G, Inbred C57BL, Karkare Swagata, Knockout, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Male, Manganese/metabolism/*toxicity, Membrane Proteins/genetics/*metabolism, Mice, Motor Activity, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
The effect of manganese exposure in Atp13a2-deficient mice.
Tags: *Alpha-synuclein, *Lipofuscin, *Manganese, *Mice, *Parkinson's disease, *Sensorimotor function, 2018, Aga Diana S, Department of Pharmaceutical Sciences, Ekhator Osunde R, Fleming Sheila M, Holden John G, Karkare Swagata, Lemkuhl Andrew, Linn Stephen C, Liou Benjamin, Mullin Elizabeth J, NEOMED College of Pharmacy, Neurotoxicology, Pamphile Shanta, Roth Jerome A, Santiago Nicholas A, Schultheis Patrick J, Shull Gary E, Sun Ying
Exacerbation of sensorimotor dysfunction in mice deficient in Atp13a2 and overexpressing human wildtype alpha-synuclein.
Tags: *Alpha-synuclein, *ATP13A2, *Mice, *Phenotype, *Sensorimotor, 2018, Adenosine Triphosphatases/*deficiency/genetics, alpha-Synuclein/genetics/*metabolism, Animal, Animals, Behavioural brain research, Blackwood Rachel, Body Temperature, Body Weight, Department of Pharmaceutical Sciences, Dirr Emily R, Disease Models, Ekhator Osunde R, Female, Fleming Sheila M, Gait Disorders, Holden John G, Humans, Inbred C57BL, Male, Masliah Eliezer, Membrane Proteins/*deficiency/genetics, Mice, Motor Skills/physiology, NEOMED College of Pharmacy, Neurologic/*metabolism, Phenotype, Schultheis Patrick J, Severity of Illness Index, Sex Characteristics, Transgenic
Mechanisms of Gene-Environment Interactions in Parkinson's Disease.
Tags: *Alpha-synuclein, *ATP13A2, *Gene-Environment Interaction, *Genetic Predisposition to Disease, *Manganese, *Paraquat, *Parkinson Disease, *Parkinson's disease, *Rotenone, 2017, Current environmental health reports, Department of Pharmaceutical Sciences, Environmental Exposure/*adverse effects, Fleming Sheila M, Herbicides/adverse effects, Humans, Insecticides/adverse effects, Mutation/genetics, NEOMED College of Pharmacy, Paraquat/adverse effects, Risk Factors, Rotenone/adverse effects