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Text
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URL Address
<a href="http://doi.org/10.1006/exnr.2000.7515" target="_blank" rel="noreferrer noopener">http://doi.org/10.1006/exnr.2000.7515</a>
Pages
450–457
Issue
2
Volume
166
Dublin Core
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Title
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The effect of GDNF on nigrostriatal dopaminergic function in response to a two-pulse K(+) stimulation.
Publisher
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Experimental neurology
Date
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2000
2000-12
Subject
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*Nerve Growth Factors; 3; 4-Dihydroxyphenylacetic Acid/metabolism; Animals; Corpus Striatum/*drug effects/metabolism; Dopamine/*metabolism; Dose-Response Relationship; Drug; Extracellular Space/metabolism; Glial Cell Line-Derived Neurotrophic Factor; Male; Microdialysis; Nerve Tissue Proteins/*pharmacology; Neuroprotective Agents/*pharmacology; Parkinson Disease/drug therapy/metabolism; Potassium/*pharmacology; Rats; Sprague-Dawley; Substantia Nigra/*drug effects/metabolism
Creator
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Xu K; Dluzen D E
Description
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We examined the effect of glial cell line-derived neurotrophic factor (GDNF) upon nigrostriatal dopaminergic function in response to two-pulse potassium (K(+)) stimulation in rats under in vivo microdialysis conditions. The two-pulse infusion protocol permits us to focus upon the role of this neurotrophin as related to vesicular storage and release of dopamine (DA). The effects of two
Identifier
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<a href="http://doi.org/10.1006/exnr.2000.7515" target="_blank" rel="noreferrer noopener">10.1006/exnr.2000.7515</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Nerve Growth Factors
2000
3
4-Dihydroxyphenylacetic Acid/metabolism
Animals
Corpus Striatum/*drug effects/metabolism
Dluzen D E
Dopamine/*metabolism
Dose-Response Relationship
Drug
Experimental neurology
Extracellular Space/metabolism
Glial Cell Line-Derived Neurotrophic Factor
Male
Microdialysis
Nerve Tissue Proteins/*pharmacology
Neuroprotective Agents/*pharmacology
Parkinson Disease/drug therapy/metabolism
Potassium/*pharmacology
Rats
Sprague-Dawley
Substantia Nigra/*drug effects/metabolism
Xu K