Browse Items (6 total)

Tags: *Stem cells

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Alcohol abuse and disorder of granulopoiesis.

Granulocytes are the major type of phagocytes constituting the front line of innate immune defense against bacterial infection. In adults, granulocytes are derived from hematopoietic stem cells in the bone marrow. Alcohol is the most frequently…

Tags: *Stem cells, 2019, Alcohol abuse, bacterial infection, Bao Jianxin, bone marrow, cell signaling, DeLucia Angelo L, Department of Integrative Medical Sciences, Granulopoiesis, Immune defense, Leukopenia, NEOMED College of Medicine, Pharmacology & therapeutics, progenitor cells, Shi Xin, the granulopoietic response, Zhang Ping

Alignment of inducible vascular progenitor cells on a micro-bundle scaffold improves cardiac repair following myocardial infarction.

Ischemic heart disease is still the leading cause of death even with the advancement of pharmaceutical therapies and surgical procedures. Early vascularization in the ischemic heart is critical for a better outcome. Although stem cell therapy has…

Tags: *Cardiovascular regeneration, *Ischemic heart diseases, *Micro-bundle scaffold, *Myocardial infarction, *Neovascularization, *Stem cells, *Tissue Scaffolds, *Vascular progenitor cells, 2017, Animal, Animals, Basic research in cardiology, Cell Differentiation, Cell Proliferation, Cell Survival, Cells, Chilian William M, Coculture Techniques, Cultured, Cumpston Devan, Department of Integrative Medical Sciences, Disease Models, Dong Feng, Endothelial Progenitor Cells/metabolism/*transplantation, Enrick Molly, Fibroblast Growth Factor 2/metabolism, Hakobyan Tatev, Jamaiyar Anurag, Janota Danielle, Kolz Christopher L, Lactic Acid/*chemistry, Muscle, Myocardial Infarction/metabolism/pathology/physiopathology/*surgery, Myocardium/metabolism/*pathology, Myocytes, NEOMED College of Medicine, Newby Bi-Min Zhang, Ohanyan Vahagn, Paracrine Communication, Phenotype, Physiologic, Polyglycolic Acid/*chemistry, Polylactic Acid-Polyglycolic Acid Copolymer, Rats, Signal Transduction, Smooth, Smooth Muscle/metabolism/*transplantation, Song Hokyung, Sprague-Dawley, Stevanov Kelly, Time Factors, Tissue Engineering/*methods, Vascular Endothelial Growth Factor A/metabolism, Vascular/metabolism/*transplantation, Ventricular Remodeling, Wan Weiguo, Yin Liya

Are stem cells the teacher or the student?

PURPOSE OF REVIEW: Stem cell-based therapies for preventing and treating chronic end-organ dysfunction have captured the imagination of the lay public and spurred scientific and clinical development in multiple disciplines and disease states. The…

Tags: *Stem Cell Transplantation, *Stem cells, 2012, Bone Marrow/physiopathology, Current opinion in organ transplantation, Humans, Penn Marc S, Regeneration, Tissue Engineering, Wounds and Injuries/*physiopathology/*surgery

Cell transplantation as an initiator of endogenous stem cell-based tissue repair.

PURPOSE OF REVIEW: The aim of this review is to summarize recent findings of endogenous cell-based tissue repair triggered by a multitude of approaches, especially stem cell therapy. RECENT FINDINGS: The emerging evidence has demonstrated that an…

Tags: *Regeneration, *Stem Cell Transplantation, *Stem cells, *Wound Healing, 2012, Caplan Arnold I, Cell Transplantation, Current opinion in organ transplantation, Department of Integrative Medical Sciences, Dong Feng, Humans, Mesenchymal Stem Cell Transplantation, NEOMED College of Medicine

Impairment of Hematopoietic Precursor Cell Activation during the Granulopoietic Response to Bacteremia in Mice with Chronic-Plus-Binge Alcohol Administration.

Alcohol abuse impairs immune defense. To study the effect of chronic-plus-binge alcohol exposure on the granulopoietic response, acute alcohol intoxication (intraperitoneal injection of 5 g alcohol/kg body weight) was introduced to mice chronically…

The Unraveling of the Matryoshka Doll.

Tags: *chemokines, *exosomes, *heart failure, *Myocardial infarction, *Stem cells, 2017, Adult, Adult Stem Cells/metabolism/*transplantation, Circulation research, Exosomes/genetics/metabolism, Gene Expression, Heart Diseases/physiopathology/*therapy, Humans, MicroRNAs/genetics/metabolism, Penn Marc S, Regenerative Medicine/methods/trends, Stem Cell Transplantation/*methods

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