Browse Items · NEOMED Bibliography Database

Immunohistochemical localization of substance P, somatostatin, enkephalin, and serotonin in the spinal cord of the northern leopard frog, Rana pipiens.

Using the indirect antibody peroxidase-antiperoxidase method of Sternberger, we localized substance P (SP), somatostatin (SOM), enkephalin (ENK), and serotonin (5HT, 5-hydroxytryptamine) in the spinal cord of Rana pipiens. This is the first study to…

Tags: 1988, Adli D S, Animals, Cruce W L, Enkephalins/analysis, Ho R H, Immunoenzyme Techniques, Male, Neuropeptides/*analysis, Rana pipiens/anatomy & histology/*metabolism, Rosenthal B M, Serotonin/analysis, Somatostatin/analysis, Spinal Cord/*analysis, Substance P/analysis, The Journal of comparative neurology, Yuen G L

Role of prostaglandins in blood-induced vasoconstriction of canine cerebral arteries.

We tested the hypothesis that the vasoconstriction produced by the application of blood to the adventitial surfaces of the vessels of an isolated perfused canine circle of Willis preparation was mediated by products of prostaglandin metabolism. In…

Impaired reception of nonverbal cues in women with premenstrual tension syndrome.

The ability to perceive nonverbal facial cues was tested in 30 White, middle-class females. Pre- and post-menses responses of 15 subjects diagnosed as having Premenstrual Tension Syndrome (PMS) were compared to the responses of age-matched controls.…

Tags: *Facial Expression, 1988, Adult, Bates L, Cues, Female, Gambling, Giannini A J, Humans, Martin D M, Menstrual Cycle, Premenstrual Syndrome/*psychology, Sorger L G, The Journal of psychology, Videotape Recording

Effect of pathological blood histamine levels on canine coronary vascular permeability.

We evaluated the effect of systemically administered histamine on coronary vascular permeability (CVP) of pentobarbital-anesthetized, open-chest dogs with and without beta-receptor blockade. We determined changes in CVP by comparing prenodal cardiac…

Tags: *Capillary Permeability, *Coronary Circulation, 1988, Animals, Blood Proteins/analysis, Dogs, Female, Hemodynamics, Histamine/*blood, Lymph/analysis, Male, Maron M B, Microcirculation, Pilati C F, The American journal of physiology

Calculation of the reflection coefficient from measurements of endogenous vascular indicators.

The solvent drag reflection coefficient (sigma) for total proteins can be estimated by comparing the relative degrees of concentration of erythrocytes and plasma proteins that occur during fluid filtration in an isolated perfused organ. In this…

Tags: 1988, Animals, Blood Proteins/*analysis, Blood Volume, Capillary Permeability, Filtration, Humans, Journal of applied physiology (Bethesda, Md. : 1985), Maron M B, Mathematics, Methods, Models, Pilati C F, Theoretical

Effect of papaverine on pulmonary vascular permeability to proteins.

Previous studies have suggested that papaverine, a drug commonly used in studies of transvascular fluid and solute exchange to eliminate confounding effects of changes in vascular tone, may itself increase vascular permeability. In this study, we…

Tags: 1988, Animals, Blood Proteins/*metabolism, Capillary Permeability/*drug effects, Dogs, Female, In Vitro Techniques, Journal of applied physiology (Bethesda, Md. : 1985), Male, Maron M B, Osmosis, Papaverine/blood/*pharmacology, Pilati C F, Pulmonary Circulation/*drug effects, Serotonin/pharmacology, Vasodilation/drug effects, Water-Electrolyte Balance/drug effects

Evaluation of venous distension device: phase II: cannulation of nonemergent patients.

A device designed to augment venous filling by applying a vacuum to the arm during tourniquet application was evaluated in adult patients considered to have difficult peripheral venous access and in need of nonemergent venipuncture or intravenous…

Tags: 1988, Adolescent, Adult, Amsterdam J T, Catheterization, Evaluation Studies as Topic, Hedges J R, Humans, Middle Aged, Obesity/physiopathology, Peripheral/instrumentation/*methods, Punctures/*methods, Schwytzer D J, The American journal of emergency medicine, Tourniquets, Weinshenker E

Norfenfluramine, the fenfluramine metabolite, provides stimulus control: evidence for serotonergic mediation.

Nine male rats were trained to discriminate 1.4 mg/kg norfenfluramine (NF) from its vehicle using a two-lever, food-motivated, operant discrimination task. Once trained, the rats showed a dose-dependent decrease in responding on the

Tags: 1988, Animal/*drug effects, Animals, Behavior, Boja J W, Discrimination (Psychology)/*drug effects, Dose-Response Relationship, Drug, Fenfluramine/*analogs & derivatives/*pharmacology, Inbred Strains, Male, Norfenfluramine/*pharmacology, Pharmacology, biochemistry, and behavior, Rats, Receptors, Schechter M D, Serotonin/pharmacology, Serotonin/physiology, Time Factors

Correlates of screening mammography in a family practice setting.

The medical records of 243 asymptomatic women aged 50 years or older were reviewed at a community-based family practice center to determine the proportion who had been referred for a screening mammogram and to identify correlates of mammography…

Tags: *Family Practice, *Mammography, *Referral and Consultation, 1988, Aged, Bourguet C C, Breast Neoplasms/diagnostic imaging, Female, Gilchrist V J, Humans, Kandula M, Middle Aged, Retrospective Studies, Risk Factors, The Journal of family practice

A comparison of awake and sleeping cortical states by analysis of the somatosensory-evoked response of postcentral area 1 in rhesus monkey.

The response of primary somatosensory cortex (SI) to cutaneous stimulation of the hand was studied in one unanesthetized monkey to examine more closely the previously reported dependence of a behaviorally relevant late component of the evoked…

Tags: 1988, Animals, Arousal, Cauller L J, Cerebral Cortex/*physiology, Electroencephalography, Evoked Potentials, Experimental brain research, Kulics A T, Macaca mulatta, Sleep/*physiology, Somatosensory, Wakefulness/*physiology

Evolution of the reticular formation.

The reticular formation of mammals contains numerous nuclei which can be recognized by their projection patterns, cytoarchitectonics, and neuropeptide/neurotransmitter content. We have identified reticular nuclei in representatives from numerous…

Tags: 1988, Acta biologica Hungarica, Animals, Biological Evolution, Cruce W L, Fishes, Mammals, Newman D B, Phylogeny, Reptiles, Reticular Formation/*physiology, Stuesse S L

The nucleotide sequence of rabbit liver cytochrome b5 mRNA.

Using a synthetic 26 base pair (bp) oligonucleotide, we have screened a rabbit liver cDNA library in lambda gt11 and isolated a 1000 bp DNA clone corresponding to cytochrome b5 mRNA. The clone contains the complete coding region and long 5' and 3'…

Tags: 1988, Amino Acid Sequence, Animals, Base Sequence, Chromosome Deletion, Cloning, Cytochrome b Group/*genetics, Cytochromes b5, Dariush N, Fisher C W, Genes, Liver/*metabolism, Messenger/*genetics, Molecular, Molecular Sequence Data, Protein sequences & data analysis, Rabbits, RNA, Steggles A W

Immunocytochemical analysis of somatostatin in the hypothalamus of obese and non-obese Zucker rats.

Levels of growth hormone (GH) are reduced in the genetically obese Zucker rat, fa/fa, in comparison to lean littermates. In normal rats, GH release is regulated by stimulatory and inhibitory factors of hypothalamic origin. The present experiment…

Tags: 1988, Animals, Brain research, DonCarlos L L, Finkelstein J A, Ho R H, Hypothalamus/*cytology/pathology, Immunoenzyme Techniques, Obesity/*metabolism, Rats, Somatostatin/*analysis/immunology, Species Specificity, Zucker

An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates.

An improved, HPLC with electrochemical detection method for the isocratic separation and determination of amino acids from post-mortem brain tissue and from microdialysates of awake-behaving animals is described. Optimal conditions that maximize…

Tags: *Brain Chemistry, 1988, Amino Acids/*analysis, Animals, Chromatography, Corpus Striatum/analysis, Dialysis, Donzanti B A, Electrochemistry, High Pressure Liquid/*methods, Inbred Strains, Life sciences, Male, Neurotransmitter Agents/*analysis, Rats, Yamamoto B K

A rapid and simple HPLC microassay for biogenic amines in discrete brain regions.

A rapid microassay is described for the measurement of biogenic amines using an isocratic HPLC system with electrochemical detection. Catecholamines, indoleamines and their major metabolites were extracted with 150 microliters of perchloric acid from…

Tags: *Brain Chemistry, 1988, Animals, Biogenic Amines/*analysis, Chromatography, Corpus Striatum/analysis, Donzanti B A, High Pressure Liquid/methods, Inbred Strains, Indicators and Reagents, Male, Nucleus Accumbens/analysis, Organ Specificity, Pharmacology, biochemistry, and behavior, Rats, Reference Values, Yamamoto B K

Acute urinary retention.

Acute urinary retention is a common emergency genitourinary symptom. The etiology of acute retention includes obstructive, neurogenic, pharmacologic, and psychogenic causes. The emergency management of acute urinary retention is bladder…

Tags: 1988, Emergencies, Emergency medicine clinics of North America, Female, Fontanarosa P B, Humans, Male, Physical Examination, Roush W R, Urinary Bladder, Urinary Catheterization, Urination, Urination Disorders/diagnosis/*etiology/physiopathology/therapy

Radiologic contrast-induced renal failure.

RCIRF is a complex syndrome resulting in acute renal dysfunction following exposure to radiologic contrast media. It accounts for 10 per cent of all cases of acute renal failure. The pathogenesis appears multifactorial but most probably involves…

Tags: 1988, Acute Kidney Injury/*chemically induced/epidemiology/physiopathology/therapy, Contrast Media/*adverse effects, Emergencies, Emergency medicine clinics of North America, Fontanarosa P B, Humans, Risk Factors

Aspartame exposure and in vitro hippocampal slice excitability and plasticity.

Aspartame (APM) is a low-calorie sweetener recently approved and released for widespread use in the United States. However, concerns still exist that APM consumption may be responsible for adverse neurological and psychological effects in some…

Tags: 1988, Animals, Aspartame/*toxicity, Dipeptides/*toxicity, Electric Stimulation, Electrophysiology, Female, Fountain S B, Fundamental and applied toxicology : official journal of the Society of Toxicology, Hennes S K, Hippocampus/*drug effects/physiopathology, Neuronal Plasticity/*drug effects, Neurons/drug effects, Rats, Teyler T J, Time Factors

Triethyltin exposure suppresses synaptic transmission in area CA1 of the rat hippocampal slice.

To examine the effects of TET on the electrophysiology of area CA1 of hippocampus, hippocampal slices were obtained from adult hooded rats and were maintained in vitro using standard techniques. Stimulating and recording electrodes were placed in the…

Tags: 1988, Animals, Evoked Potentials/drug effects, Female, Fountain S B, Hennes S K, Hippocampus/drug effects/*pathology/physiology, In Vitro Techniques, Neurotoxicology and teratology, Pyramidal Tracts/drug effects/*pathology/physiology, Rats, Synapses/drug effects/*physiology, Synaptic Transmission/*drug effects, Teyler T J, Ting Y L, Trialkyltin Compounds/*toxicity, Triethyltin Compounds/*toxicity

Clonidine in the treatment of premenstrual syndrome: a subgroup study.

The authors studied the effects of clonidine on a subgroup of women who had symptoms associated with premenstrual syndrome; the subgroup comprised 24 women aged 19 to 41 years who had "moderate" to "severe" cyclic decreases in beta-endorphin levels.…

Tags: 1988, Adult, beta-Endorphin/blood, Clinical Trials as Topic, Clonidine/*therapeutic use, Double-Blind Method, Female, Giannini A J, Humans, Loiselle R H, Placebos, Premenstrual Syndrome/blood/*drug therapy/psychology, Psychiatric Status Rating Scales, Sarachene J, Sullivan B, The Journal of clinical psychiatry

Drug abuse and depression: possible models for geriatric anorexia.

The central biochemical pathology of anorexia and the natural aging of the brain is similar. Biochemical models for drug withdrawal and depression may also assist in understanding geriatric anorexia. Norepinephrine, corticotropin releasing factor and…

Tags: 1988, Aged, Aging/metabolism/*physiology, Anorexia/etiology/*physiopathology, Corticotropin-Releasing Hormone/physiology, Depression/etiology/*physiopathology, Dopamine/physiology, Feeding and Eating Disorders/*physiopathology, Giannini A J, Humans, Morphine/pharmacology, Neurobiology of aging, Norepinephrine/physiology, Substance-Related Disorders/complications/*physiopathology

Changing concepts of deep venous thrombosis of the upper extremity–report of a series and review of the literature.

Deep venous thrombosis (DVT) of the upper extremity has recently been recognized as being more common than previously reported (probably because of the increasingly frequent use of subclavian venous access). A retrospective review of patients in whom…

Continuous emergency department monitoring of arterial saturation in adult patients with respiratory distress.

Continuous measurement of arterial oxygen saturation (SaO2) using pulse oximetry has become a common monitoring and management technique in critically ill hospitalized patients. To determine the impact of SaO2 monitoring on emergency patient…

Emergency department protocol for the diagnosis and evaluation of geriatric abuse.

As the number of elderly persons in the United States continues to increase, geriatric abuse has become the most recent manifestation of domestic violence seen in the emergency department. Recent data suggest that 1 million elderly persons are…

Tags: *Elder Abuse, *Emergency Service, 1988, Aged, Annals of emergency medicine, Clinical Protocols, Cunningham W, Dougherty J, Family, Female, Hospital, Humans, Jones J, Male, Ohio, Psychological/diagnosis/epidemiology, Retrospective Studies, Schelble D, Stress

Inhibition of rat brain pyruvate dehydrogenase by thiamine analogs.

The effects of thiamine thiazolone (TT) and thiamine thiazolone pyrophosphate (TTPP) on the in vitro and in vivo inhibition of pyruvate dehydrogenase complex (PDHC) from rat cortex and hippocampus were characterized. TTPP decreased PDHC activity in…

Tags: 1988, Animals, Biochemical pharmacology, Brain/*enzymology, Cerebral Cortex/drug effects/enzymology, Hippocampus/drug effects/enzymology, Inbred Strains, Kandiko C T, Kinetics, Male, Pyruvate Dehydrogenase Complex/*antagonists & inhibitors, Rats, Smith D, Thiamine Pyrophosphate/analogs & derivatives/pharmacology, Thiamine/*analogs & derivatives/pharmacology, Yamamoto B K

Gallstone pancreatitis: a prospective randomized trial of the timing of surgery.

The correct timing of surgery in cases of gallstone pancreatitis is debatable. To delineate more clearly the influence of the timing of surgery in the treatment of the disease, a prospective randomized clinical study of early surgery (less than 48…

Life prolongation: views of elderly outpatients and health care professionals.

A peculiar dynamic in communication exists between those who are most likely to be involved in life-prolongation decisions. We found that both the elderly and health care professionals talk about life-prolongation, but not with one another; that they…

The accuracy of alkaline phosphatase isoenzyme determination.

Alkaline phosphatase isoenzyme determination (APID) is in common use despite evidence suggesting that the results correlate poorly with actual sites of disease. To assess the predictive value of this test in clinical practice, 99 APIDs performed on…

Tags: 1988, Aged, Alkaline Phosphatase/*blood, Bone Diseases/diagnosis, Clinical Enzyme Tests/*standards, Female, Humans, Isoenzymes/*blood, Journal of general internal medicine, Lamb G C, Liver Diseases/diagnosis, Male, Retrospective Studies, Roush G

Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex.

Male rats were trained to discriminate the stimulus effects of CGS 9896 (30.0 mg/kg) from its vehicle. Once trained, discriminative performance was observed to be dose-responsive in the 3.75-30.0 mg/kg range and analysis of the dose-response curve…

Discriminative stimulus control by the anxiogenic beta-carboline FG 7142: generalization to a physiological stressor.

Drug discrimination was employed to investigate the similarities between FG

Tags: 1988, Animals, Appetite Depressants/*pharmacology, Avoidance Learning/drug effects, Carbolines/*pharmacology, Discrimination Learning/*drug effects, Generalization, Inbred Strains, Leidenheimer N J, Male, Pharmacology, biochemistry, and behavior, Physiological/*psychology, Rats, Schechter M D, Stimulus/*drug effects, Stress

Maximal aerobic power after competitive marathon running.

We evaluated the ability of a group of male runners (n = 4) to do maximal and submaximal exercise before and after they ran a competitive marathon (42.2 km) race. VO2max was determined 3 to 6 times in each runner, on alternate days, 1-4 weeks prior…

Tags: *Physical Exertion, *Running, 1988, Adult, Blood Chemical Analysis, Canadian journal of sport sciences = Journal canadien des sciences du sport, Exercise Test, Hematocrit, Hemoglobins/analysis, Horvath S M, Humans, Male, Maron M B, Oxygen Consumption, Oxygen/*physiology

Transcatheter retrieval of intracoronary detached angioplasty guidewire segment.

A transcatheter technique of removing a detached angioplasty guidewire segment from the diagonal branch of the left anterior descending coronary artery is described. A standard 0.014 angioplasty guidewire was modified into a "snare" apparatus for…

Tags: *Coronary Vessels, 1988, Aged, Angioplasty, Balloon/*adverse effects/instrumentation, Catheterization and cardiovascular diagnosis, Catheterization/*methods, Coronary Angiography, Coronary Disease/therapy, Equipment Failure, Female, Foreign Bodies/*therapy, Hanson M W, Humans, Mikolich J R

Segmental splenectomy using the ultrasonic surgical aspirator.

The technique described seems to significantly decrease blood loss in segmental splenectomy. Resection of the damaged splenic segments offers the potential advantage of reducing rebleeding and secondary hemorrhage from sites of repaired lacerations.…

Tags: *Surgical Instruments, 1988, American journal of surgery, Evans D M, Humans, Moorman D W, Splenectomy/*methods, Ultrasonic Therapy/*instrumentation, Wright D J

A critical period for long-term potentiation in the developing rat visual cortex.

The in vitro rodent visual cortical slice preparation demonstrates a critical period for long-term potentiation (LTP). Current source density (CSD) analysis reveals peak potentiation of both supra-(layers II-III) and infragranular (layers V) layers…

Tags: 1988, Aging, Animals, Brain research, Electric Stimulation, In Vitro Techniques, Neuronal Plasticity, Newborn, Perkins A T 4th, Rats, Teyler T J, Visual Cortex/*growth & development/physiology

Pharmacologic management of eating disorders.

Treatment of eating disorders is difficult regardless of the methods employed. Pharmacologic management in anorexia nervosa and in bulimia nervosa is especially helpful when it is part of a multimodal treatment approach that includes individual,…

Tags: 1988, American family physician, Anorexia Nervosa/*drug therapy/psychology, Antidepressive Agents, Behavior Therapy, Bulimia/*drug therapy/psychology, Combined Modality Therapy, Female, Humans, Male, Monoamine Oxidase Inhibitors/therapeutic use, Price W A, Sex Factors, Tricyclic/*therapeutic use

Herpes simplex virus type 1 penetration initiates mobilization of cell surface proteins.

Changes in membrane structure resulting from herpes simplex virus 1 (HSV-1) penetration were detected using fluorescence photobleaching recovery methods. The effect could be blocked by inhibitors of viral and cellular processes involved in virus…

Advantages and disadvantages of a rapid method to train drug discrimination.

In an effort to reduce the often extensive period of time needed to train rats to discriminate between a drugged and nondrugged state, a fast training regimen was employed with 1.5 mg/kg 3,4-methylenedioxymethamphetamine (MDMA) used as the training…

Tags: 1988, 3, 4-methylenedioxyamphetamine, 4-Methylenedioxyamphetamine/analogs & derivatives/*pharmacology, Amphetamines/*pharmacology, Animals, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Tolerance, Male, Methods, N-Methyl-3, Pharmacology, biochemistry, and behavior, Rats, Schechter M D

CGS 10746B is able to attenuate the effects of amphetamine: further evidence for dopaminergic mediation.

Previous results indicate that agents which either decreases synthesis or block postsynaptic dopamine receptors will attenuate the discriminative stimulus produced by d-amphetamine. CGS 10746B has been reported to decrease dopamine release without…

Tags: 1988, Alkaloids/pharmacology, Animals, Antipsychotic Agents/*pharmacology, Apomorphine/pharmacology, Boja J W, Cocaine/pharmacology, Conditioning, Dextroamphetamine/antagonists & inhibitors/*pharmacology, Discrimination (Psychology)/*drug effects, Dopamine/*physiology, Dose-Response Relationship, Drug, Male, Operant/drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Thiazepines/*pharmacology

Interaction of ethanol and tetrahydro-beta-carboline (THBC) in a discriminative task.

Rats (n = 10) were trained to discriminate between ethanol (600 mg/kg, IP) and its vehicle, or between THBC (20 mg/kg) and its vehicle in a two-lever food-motivated operant task. Once the discriminative training criterion was attained, rats in each…

Tags: 1988, Alcohol (Fayetteville, N.Y.), Animal/drug effects, Animals, Behavior, Carbolines/*pharmacology, Conditioning (Psychology)/drug effects, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Interactions, Ethanol/*pharmacology, Inbred Strains, Male, Rats, Schechter M D, Signs S A

Lack of generalization of nisoxetine with amphetamine in the rat.

Rats were trained to discriminate between the stimulus properties of intraperitoneally administered d-amphetamine (0.8 mg/kg) and its vehicle in a two-lever, food-motivated operant task. Once trained, doses of the norepinephrine reuptake inhibiting…

Tags: *Discrimination (Psychology), 1988, Animals, Boja J W, Conditioning, Dextroamphetamine/*pharmacology, Dose-Response Relationship, Drug, Fluoxetine/*analogs & derivatives/pharmacology, Inbred Strains, Male, Norepinephrine/antagonists & inhibitors, Operant/*drug effects, Pharmacology, biochemistry, and behavior, Rats, Reference Values, Schechter M D

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