Browse Items · NEOMED Bibliography Database

Developmental changes in levels of growth hormone mRNA in Zucker rats.

Levels of pituitary growth hormone (GH) messenger RNA (mRNA) were compared in groups of genetically obese (fa/fa) and lean (Fa/-) littermate male Zucker rats at four different ages, 3, 5, 9, and 11 weeks, in order to determine the earliest age at…

Two components of long-term potentiation induced by different patterns of afferent activation.

Long-term potentiation (LTP) of excitatory synaptic transmission could be a mechanism underlying memory. Induction of LTP requires Ca2+ influx into postsynaptic neurons through ion channels gated by NMDA (N-methyl-D-aspartate) receptors in…

Tags: 1990, 2-Amino-5-phosphonovalerate/*pharmacology, Afferent Pathways/physiology, Animals, Calcium/*physiology, Grover L M, Hippocampus/*physiology, In Vitro Techniques, Membrane Potentials, Memory/*physiology, N-Methyl-D-Aspartate/*physiology, Nature, Neuronal Plasticity, Receptors, Synaptic Transmission, Teyler T J, Time Factors

Macromolecular transport in canine coronary microvasculature.

Coronary vascular osmotic reflection coefficients (sigma dS) for total protein, albumin (Alb), immunoglobulin (Ig)G, and IgM were determined in the anesthetized dog. Myocardial lymph was collected from the anterior interventricular lymphatic trunk,…

Pulmonary vasoconstriction in a canine model of neurogenic pulmonary edema.

The intracisternal administration of veratrine to the chloralose-anesthetized dog produces pulmonary hypertension (PH) and neurogenic pulmonary edema (NPE). To determine whether pulmonary vasoconstriction, mediated by a circulating agent, contributes…

Administration of a synthetic antiprotease reduces smoke-induced lung injury.

Our previous studies suggest that a neutrophil-mediated inflammatory injury causes a major fraction of the pulmonary edema that occurs after smoke inhalation. Because activated neutrophils extrude cytotoxic proteases, the current study was conducted…

Role of hemodynamics and vagus nerves in development of fibrin-induced pulmonary edema.

The rapid development of pulmonary edema that may occur in the rabbit after the intracisternal injection of a mixture of fibrinogen and thrombin has classically been considered to result from a vagally mediated increase in vascular permeability (G.…

Quantitation of abnormal 67Ga uptake in pulmonary interstitial vascular disease–a new test to detect diffuse lung disease.

Gallium 67 has been used as a modality to diagnose and follow the clinical course of diseases such as tumors, infections, inflammatory disorders, and interstitial lung disease. It has been appreciated, however, that mild to moderate changes in scan…

Urgent management of a giant scrotal hernia.

An unusual case of giant scrotal hernia is presented. Hernias of this magnitude are extremely rare, even in underdeveloped countries, and their repair is challenging to the surgeon and stressful to the patient. Only a few case reports on the use of…

Tags: 1990, Abdu R A, Abscess/etiology/therapy, Diabetes Complications, Genital Diseases, Hernia/complications, Herniorrhaphy, Humans, Male, Male/complications/surgery, Middle Aged, Postoperative Complications/therapy, Scrotum/*surgery, The American surgeon

The analysis of RNA by in situ agarose gel hybridization is more sensitive than the equivalent northern blot analysis.

Tags: *Blotting, *Molecular Probe Techniques, *Nucleic Acid Hybridization, 1990, Agar Gel, Ahmad I, Animals, BioTechniques, Electrophoresis, Finkelstein J A, Growth Hormone/genetics, Messenger/*analysis, Northern, Rats, RNA, Steggles A W, Zucker

A slice preparation preserving the callosal projection to contralateral visual cortex.

Due to the curved path they follow, the visual callosal projections to areas OC1 and OC2 of the rat visual cortex have been inaccessible to studies using brain slices. In this paper we describe a new slice preparation in which a curved cutting blade…

Tags: *Synaptic Transmission, 1990, Animals, Berry R L, Corpus Callosum/*physiology, Electrophysiology, Female, In Vitro Techniques, Inbred Strains, Journal of neuroscience methods, Male, Neurology/instrumentation, Nowicky A, Rats, Teyler T J, Visual Cortex/*physiology

Increased drug sensitivity in the drug discrimination procedure afforded by drug versus drug training.

Rats were trained to discriminate norfenfluramine (NF) 1.4 mg/kg from its vehicle or amphetamine (AMPH) 0.8 mg/kg or pentobarbital (PB) 6.0 mg/kg in order to determine the role that drug combination training plays in the rate of learning and…

Tags: 1990, Amphetamine/pharmacology, Animals, Boja J W, Discrimination (Psychology)/*drug effects, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Inbred Strains, Male, Norfenfluramine/pharmacology, Pentobarbital/pharmacology, Psychopharmacology, Rats, Reinforcement Schedule, Schechter M D

Regulation of cholesterol 7 alpha-hydroxylase in the liver. Purification of cholesterol 7 alpha-hydroxylase and the immunochemical evidence for the induction of cholesterol 7 alpha-hydroxylase by cholestyramine and circadian rhythm.

Two cholesterol 7 alpha-hydroxylase isozymes were purified from liver microsomes of cholestyramine-treated female rats by using anion exchange high performance liquid chromatography. These two cytochrome P-450 isozymes were similar in electrophoretic…

Hyperacute T-wave criteria using computer ECG analysis.

Hyperacute T waves (HATWs) have been described as tall-amplitude, primary T-wave abnormalities sometimes seen in the early phases of transmural myocardial infarction. Despite numerous human and animal studies addressing the presence and significance…

Hyperprolactinemia preferentially inhibits erectile function in adrenalectomized male rats.

To determine if the inhibitory effects of hyperprolactinemia on sexual arousal and serum LH levels could be dissociated from those on erectile function, copulatory behavior was examined in pituitary-grafted, adrenalectomized male rats that had been…

Tags: *Penile Erection/drug effects, 1990, Adrenalectomy, Animals, Body Weight, Chronic Disease, Doherty P C, Hyperprolactinemia/*physiopathology, Inbred F344, Life sciences, Luteinizing Hormone/blood/*metabolism, Male, Matt K S, Pituitary Gland/transplantation, Prolactin/blood/metabolism, Rats, Testosterone/pharmacology, Wu D E

Alterations in neurotransmitter amino acid content in the aging rat striatum are subregion dependent.

The topographical distribution of putative neurotransmitter amino acids in both

Tags: 1990, Aging/*metabolism, Amino Acids/*analysis, Animals, Corpus Striatum/*analysis, Donzanti B A, Inbred F344, Male, Neurobiology of aging, Neurotransmitter Agents/*analysis, Rats, Ung A K

Occupational considerations for the prehospital care provider.

Contemporary prehospital personnel are facing the major issues of infectious disease exposure, malpractice, attrition, and career opportunities in their challenging and demanding profession. Successful prehospital emergency medicine is contingent not…

Tags: *Emergency Medicine, 1990, Burnout, Career Choice, Career Mobility, Communicable Disease Control, Emergency medicine clinics of North America, Fontanarosa P B, Humans, Job Satisfaction, Malpractice, Occupational Diseases/prevention & control, Professional/etiology

Toxic streptococcal syndrome.

The streptococcal toxic shocklike syndrome is a recently recognized, multisystem disorder that shares many of the features of staphylococcal toxic shock syndrome, but is caused by toxins elaborated by group A beta-hemolytic Streptococcus. We describe…

Tags: 1990, Adult, Annals of emergency medicine, Department of Emergency Medicine, Diagnosis, Differential, Emergency Service, Female, Fontanarosa P B, Gallo U E, Hospital, Humans, NEOMED College of Medicine, Pharyngitis/*complications, Septic/blood/*diagnosis/etiology, Shock, Sinusitis/*complications, Streptococcal Infections/*complications, Streptococcus pyogenes

Anorexia and bulimia.

Anorexia nervosa and bulimia nervosa are eating disorders with distinct clinical presentations. Reduced caloric intake, a hallmark of both disorders, is manifested by self-induced starvation in anorexia and by binge eating and gastrointestinal…

Tags: 1990, Adolescent, Adult, American family physician, Anorexia Nervosa/complications/diagnosis/*therapy, Bulimia/complications/diagnosis/*therapy, Combined Modality Therapy, Diagnosis, Differential, Female, Giannini A J, Gold M, Humans, Male, Newman M

Cardiomyocyte aging and hypertrophy: atrial and ventricular changes in normal and myopathic Syrian hamsters.

Cardiac eccentric hypertrophy is associated with complex architectural and metabolic alterations. Atrial and ventricular myocyte diameters in cardiomyopathic (Bio 14.6) and age-matched control (F1b) Syrian hamsters were compared and histopathology…

Tags: 1990, Aging/*pathology, Animals, Bissler J J, Cardiomegaly/*pathology, Cricetinae, Electron, Female, Gilloteaux J, Heart Atria/pathology/ultrastructure, Heart Ventricles/pathology/ultrastructure, Jarjoura D, Journal of submicroscopic cytology and pathology, Kondolios P, Mesocricetus, Microscopy, Myocardium/*cytology/pathology/ultrastructure

Light and electron microscopical immunolocalization of neuropeptide Y-containing nerves in the hamster gallbladder.

Neuropeptide Y (NPY)-containing nerve structures were detected in the Syrian hamster gallbladder by using peroxidase-antiperoxidase immunohistochemical staining and immunoelectron microscopic techniques. In addition, Alcian blue-P.A.S. was used to…

Differential effects of NMDA receptor antagonist APV on tetanic stimulation induced and calcium induced potentiation.

Enduring synaptic potentiation can be induced in area CA1 of hippocampus by tetanic stimulation and by exposure to a medium containing high Ca2+ concentration. Both tetanic stimulation and high Ca2+ induce potentiation through voltage-dependent,…

Tags: 1990, 2-Amino-5-phosphonovalerate/*pharmacology, Action Potentials/drug effects, Animals, Calcium/*pharmacology, Electric Stimulation, Grover L M, Hippocampus/drug effects/*physiology, In Vitro Techniques, N-Methyl-D-Aspartate, Neuronal Plasticity/*drug effects, Neuroscience letters, Neurotransmitter/antagonists & inhibitors/*physiology, Receptors, Teyler T J

Effects of extracellular potassium concentration and postsynaptic membrane potential on calcium-induced potentiation in area CA1 of rat hippocampus.

Long-lasting potentiation can be induced in area CA1 of hippocampus by a relatively brief (7-10 min) exposure to a higher (4.0 mM) than normal (2.0 mM) extracellular calcium concentration. We have found that long-lasting calcium-induced potentiation…

Tags: 1990, Action Potentials/drug effects, Animals, Brain research, Calcium/*pharmacology, Grover L M, Hippocampus/drug effects/*physiology, Membrane Potentials/drug effects, Neuronal Plasticity/*drug effects, Potassium/*pharmacology, Rats, Teyler T J

A reappraisal of appendicitis in the elderly.

Historically, appendicitis in the elderly is associated with higher morbidity and mortality. Ninety-six patients over 60 years of age with appendicitis treated over a 10-year period were reviewed. Only 20% presented classically with anorexia, fever,…

Tags: 1990, 80 and over, Aged, American journal of surgery, Appendicitis/complications/*diagnosis/mortality/surgery, Diagnosis, Differential, Female, Guyton D P, Horattas M C, Humans, Male, Middle Aged, Postoperative Complications, Retrospective Studies, Time Factors, Wu D

Tromantadine inhibits a late step in herpes simplex virus type 1 replication and syncytium formation.

Addition of tromantadine after virus penetration inhibited HSV-1 induced syncytium formation and virus production in HEp-2 and VERO cells and acted additively with neutralizing antibody in blocking virus spread and cytopathology. Inhibition of…

Variation in heart disease mortality across census tracts as a function of overdispersion and social class mixture.

Variation in heart disease (HD) mortality rates across census tracts is greater than expected given binomial error and available explanatory variables. We extended an extra-binomial variation model for rates standardized by the direct method. The…

Tags: *Demography, *Models, *Social Class, 1990, Adolescent, Adult, Aged, Department of Family & Community Medicine, Female, Heart Diseases/*mortality, Humans, Jarjoura D, Logue EE, Male, Middle Aged, NEOMED College of Medicine, Ohio/epidemiology, Statistical, Statistics in medicine

Side effects of the use of botulinum toxin for treatment of benign essential blepharospasm and hemifacial spasm.

From April 1983 to April 1988, 381 botulinum toxin injections for lid spasms were administered to 106 patients. Sixty-nine had bilateral blepharospasm and 37 had hemifacial spasm. Of the 381 injections, 308 had been given to patients who returned for…

Tags: 1990, Adolescent, Blepharoptosis/chemically induced, Blepharospasm/*drug therapy, Botulinum Toxins/*adverse effects/therapeutic use, Diplopia/chemically induced, Dry Eye Syndromes/chemically induced, Eyelid Diseases/*drug therapy, Facial Muscles/*drug effects, Female, Humans, Kalra H K, Magoon E H, Male, Ophthalmic surgery, Prognosis, Spasm/*drug therapy, Vision Disorders/chemically induced

Ethanol interoceptive cue and sleep-time duration in HAS and LAS selectively bred rats.

The drug discrimination paradigm was used to evaluate the effects of selective breeding for differential sensitivity to the hypnotic effects of ethanol. Tenth generation high alcohol sensitive (HAS) and low alcohol sensitive (LAS) rats were trained…

Tags: *Cues, *Discrimination Learning, *Hypnotics and Sedatives, 1990, Animals, Breeding, Ethanol/*pharmacology, Krimmer E C, Male, Pharmacology, biochemistry, and behavior, Phenotype, Rats, Sleep/*drug effects, Species Specificity, Time Factors

Aflatoxin B1 metabolism by 3-methylcholanthrene-induced hamster hepatic cytochrome P-450s.

We have studied the activation of aflatoxin B1 by hamster liver microsomes and purified hamster cytochrome P-450 isozymes using a umu mutagen test. The hamster liver microsomes or S-9 fractions were much more active than rat liver microsomes or S-9…

Cloning and characterization of two major 3-methylcholanthrene inducible hamster liver cytochrome P450s.

We have studied the immunochemical properties of two major 3-methylcholanthrene inducible hamster liver cytochrome P450 isozymes, P450 MC1 and P450 MC4. Immunoblots using specific antibodies against P450 MC1 and P450 MC4 demonstrated that these two…

Leiomyosarcoma of the popliteal artery. A report of two cases.

Leiomyosarcomas (LS) are relatively uncommon soft-tissue sarcomas that occasionally involve the extremities. LS are usually tumors of adults and most often involve the gastrointestinal tract and uterus. When a soft-tissue sarcoma is suspected,…

Tags: 1990, Aged, Amputation, Clinical orthopaedics and related research, Female, Humans, Leeson M C, Leiomyosarcoma/diagnostic imaging/pathology/*surgery, Makley J T, Malaei M, Male, Middle Aged, Movement, Popliteal Artery/diagnostic imaging/pathology/*surgery, Postoperative Period, Radiography

Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.

Monospecific antibody against purified rat liver cholesterol 7 alpha-hydroxylase cytochrome P-450 was used to screen a lambda gt11 cDNA library constructed from immuno-enriched polysomal RNA of cholestyramine-treated female rat liver. Two types of…

Surgical correction of rhinophyma.

Tags: 1990, Archives of dermatology, Humans, Laser Therapy, Lloyd K M, Male, Middle Aged, Rhinophyma/drug therapy/*surgery, Rosacea/*surgery, Sulfacetamide/therapeutic use, Tetracycline/therapeutic use

Modeling heart disease mortality with census tract rates and social class mixtures.

The relationship between social class and 1980 heart disease (HD) mortality in eight urban U.S. counties was examined by regressing age and sex adjusted census tract specific HD rates (N = 1211) on tract social class characteristics. The regression…

Tags: *Social Class, 1990, Coronary Disease/mortality, Demography, Department of Family & Community Medicine, Epidemiologic Methods, Heart Diseases/*mortality, Humans, Jarjoura D, Logue EE, Models, NEOMED College of Medicine, Ohio/epidemiology, Regression Analysis, Social science & medicine (1982), Statistical

Ilionguinal-iliohypogastric nerve entrapment.

Ilionguinal-iliohypogastric nerve entrapment was described as early as 1942 as a rare but proven cause of chronic inguinal pain in patients with previous lower abdominal surgery. We describe two cases of patients who presented to the emergency care…

Tags: 1990, Abdomen/*surgery, Adult, Annals of emergency medicine, Bupivacaine/therapeutic use, Cicatrix/complications, Dougherty J M, Female, Humans, Medical History Taking, Melville K, Nerve Compression Syndromes/drug therapy/*etiology/physiopathology, Pain/etiology, Physical Examination, Postoperative Complications/drug therapy/*etiology, Schultz E A

Discriminative stimulus properties of (+)cathine, an alkaloid of the khat plant.

The effects of the psychostimulant (+)cathine (norpseudoephedrine) were examined in a two-choice, food-motivated, drug-discrimination paradigm. Rats were able to discriminate cathine from vehicle and this effect was dose- and time-dependent. Prior…

Tags: *Discrimination (Psychology)/drug effects, 1990, Alkaloids/*pharmacology, Animals, Catha, Domperidone/pharmacology, Drug Administration Schedule, Drug Tolerance, Haloperidol/pharmacology, Inbred Strains, Male, Pehek E A, Pharmacology, biochemistry, and behavior, Phenylpropanolamine/antagonists & inhibitors/*pharmacology, Plant Extracts/analysis, Psychotropic Drugs/*pharmacology, Rats, Schechter M D

Effects of cathinone and amphetamine on the neurochemistry of dopamine in vivo.

The effects of (-)cathinone, the primary psychoactive alkaloid of the Khat plant, were compared to those of (+)amphetamine in the anterior caudate-putamen and the nucleus accumbens. In vivo microdialysis was used to measure extracellular levels of…

Historical perspective on the evolution of today's military field anesthesia machine.

Tags: *Equipment Design, 1990, 20th Century, Anesthesiology/history/*instrumentation, Forecasting, History, Military medicine, Military Medicine/history/*instrumentation, Petty C, United States

Methemoglobinemia secondary to aniline exposure.

Tags: 1990, Adult, Aniline Compounds/*adverse effects, Annals of emergency medicine, Chemical Industry, Department of Internal Medicine, Emergencies, Gradisek R, Heiselman D E, Humans, Male, Methemoglobinemia/*chemically induced/pathology, NEOMED College of Medicine, Occupational Diseases/chemically induced/pathology, Phillips D, Sanitary Engineering

Excessive sympathetic nervous system activity decreases myocardial contractility.

The objective of this study was to determine whether myocardial contractility is depressed by intense activation of the sympathetic nervous system. A massive sympathetic discharge was produced by injecting veratrine or sodium citrate into the…

Quality assurance in emergency medical service systems.

EMS quality assurance programs can help guarantee that the provision of prehospital care is medically accountable. The establishment and management of such a program, although time consuming, are critically important. It is essential that the medical…

Tags: *Quality Assurance, 1990, Department of Emergency Medicine, Emergency Medical Services/*standards, Emergency medicine clinics of North America, Health Care, Medical Audit, NEOMED College of Medicine, Polsky S S, Retrospective Studies, Risk Management, United States, Weigand J V

Browse Items (142 total)