Chronic Spontaneous Exercise Did Not Alter Vagal Afferent Reactivity To Mechanical Or Chemical-stimulation
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
DiCarlo S E; Scislo T
Faseb Journal
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
Ocular Vascular-disease - In-office Primary Care Diagnosis
Geriatrics & Gerontology; infection; neovascularization; retinal artery obstruction; secondary
Delaney W V
Geriatrics
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
Psychotherapy Of Sexually Abused-children And Their Families - Friedrich,wn
Behavioral Sciences; Pediatrics; Psychology
Constantinou G M
Journal of Developmental and Behavioral Pediatrics
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
Elimination Of Post-exertional Hypotension By Cardiac Afferent Blockade
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Collins H L; DiCarlo S E
Faseb Journal
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
LAPAROSCOPIC VERSUS CLINICAL-DIAGNOSIS OF ACUTE PELVIC INFLAMMATORY DISEASE
Obstetrics & Gynecology
The purpose of this study was to evaluate the accuracy of clinical diagnosis of acute pelvic inflammatory disease (PID). Data were obtained on 176 consecutive women admitted to St. Elizabeth Hospital Medical Center with a clinical diagnosis of PID. All underwent diagnostic laparoscopy. PID was established laparoscopically in 134 (76.1%) of the patients. Statistical tests for significant associations between PID and each of 21 clinical indicators of the disease were conducted using the chi2 and Mann-Whitney tests. Stepwise logistic regression was performed on those variables whose univariate tests of significant association with PID resulted in P values < 0.20. An optimal set of PID indicators consisted of adnexal tenderness, lower abdominal pain of < one week's duration and an elevated white blood cell count. Use of these indicators resulted in a test with an estimated sensitivity and specificity of 86.6% and 45.7%, respectively. Estimated predictive values for positive and negative test results were 0.84 and 0.52, respectively. These results confirm the fact that laparoscopy is the definitive diagnostic modality in PID.
Morcos R; Frost N; Hnat M; Petrunak A; Caldito G
Journal of Reproductive Medicine
1993
1993-01
Journal Article or Conference Abstract Publication
n/a
SUBNASAL MORPHOLOGICAL VARIATION IN EXTANT HOMINOIDS AND FOSSIL HOMINIDS
Anthropology; Evolutionary Biology; patterns; lake turkana; swartkrans formation; kenya; Homo; australopithecus; australopithecus-boisei; paranthropus; specimens; systematics; west
McCollum M A; Grine F E; Ward S C; Kimbel W H
Journal of Human Evolution
1993
1993-02
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1006/jhev.1993.1009" target="_blank" rel="noreferrer noopener">10.1006/jhev.1993.1009</a>
THE USE OF CULTURED EPITHELIAL AUTOGRAFTS IN THE WOUND CARE OF SEVERELY BURNED PATIENTS
skin; Pediatrics; Surgery; cells; growth; burns; clinical-application; coverage; epithelial autografts; human epidermal-keratinocytes; skin replacement
McAree K G; Klein R L; Boeckman C R
Journal of Pediatric Surgery
1993
1993-02
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/s0022-3468(05)80266-0" target="_blank" rel="noreferrer noopener">10.1016/s0022-3468(05)80266-0</a>
EFFECT OF DIGITAL RECTAL EXAMINATION (AND EJACULATION) ON SERUM PROSTATE-SPECIFIC ANTIGEN AFTER 24 HOURS - A RANDOMIZED, PROSPECTIVE-STUDY
Urology & Nephrology; adenocarcinoma; marker
The purpose of this randomized, controlled, clinical trial was to determine the effect of the digital rectal examination (DRE) on the prostate-specific antigen (PSA) serum levels in view of conflicting literature reports and screening methods and misconceptions by physicians. We showed that the DRE had no clinically important effect on PSA values twenty-four hours later. The mean PSA rose from 1.57 to 1.62 ng/mL, similar to the controls. Ejaculation had no meaningful effect on the serum PSA values.
McAleer J K; Gerson L W; McMahon D; Geller L
Urology
1993
1993-02
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0090-4295(93)90158-7" target="_blank" rel="noreferrer noopener">10.1016/0090-4295(93)90158-7</a>
CLONING AND SEQUENCING OF THE HAMSTER CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE (CYP7) AND A COMPARATIVE-ANALYSIS OF THE RAT, HAMSTER AND HUMAN CYP7 GENES
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Crestani M; Chiang J Y L
Faseb Journal
1993
1993-04
Journal Article or Conference Abstract Publication
n/a
PRIMARY CARE PHYSICIAN TRAINING IN THE NURSING-HOME - A NATIONAL SURVEY OF INTERNAL-MEDICINE AND FAMILY-PRACTICE PROGRAMS
Research & Experimental Medicine
Counsell S R; Katz P R; Karuza J
Clinical Research
1993
1993-04
Journal Article or Conference Abstract Publication
n/a
MODEL-FREE NUMERICAL DECONVOLUTION OF RECIRCULATING INDICATOR CONCENTRATION CURVES
Physiology; Sport Sciences; parameters; camera; computation; extravascular lung water; indicator dilution; pulmonary circulation; transport functions; vascular transit time
This paper investigates two model-free methods for numerical deconvolution of recirculating indicator concentration curves. The two methods, damped least squares and discrete orthogonal polynomial deconvolution, are applied to simulated data to verify the reliability of the algorithms. Both deconvolution methods provide damping that results in estimated transport functions that are smooth and reasonable estimates of the actual simulated transport function. On convolution with the simulated input curve, the estimated transport functions provide good fits to the simulated output curve. In addition, methods for identifying an optimal solution and for truncating the artifactually long oscillatory tails of the estimated transport functions are proposed, which appear to allow for reasonably accurate estimation of the mean transit times and variances of the transport functions as well. When either method was applied to indicator dilution data obtained from the pulmonary artery and left atrium, it was computationally stable while producing transport functions that when convolved with the input concentration curves provided good fits to the output concentration curves. The combined simulation and experimental results suggest that the proposed methods should be useful for estimating circulation transport functions from indicator dilution data.
Clough A V; Cui D Y; Linehan J H; Krenz G S; Dawson C A; Maron M B
Journal of Applied Physiology
1993
1993-03
Journal Article or Conference Abstract Publication
n/a
THE EXPRESSION AND REGULATION OF CHOLESTEROL 7-ALPHA-HYDROXYLASE
Chiang J Y L; Karam W G; Yang T P; Wang D P
1993
1993
Book/Monograph
n/a
ENHANCED CARDIAC RECEPTOR REGULATION OF HEART-RATE DURING EXERCISE
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Chen C Y; Collins H L; DiCarlo S E
Faseb Journal
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
DEVELOPMENTAL ALTERATIONS IN N-METHYL-D-ASPARTATE STIMULATED H-3 NOREPINEPHRINE RELEASE IN RAT-BRAIN CORTEX AND HIPPOCAMPUS
hippocampus; cortex; development; receptors; Neurosciences & Neurology; system; ethanol; postnatal-development; cerebral-cortex; visual cortex; excitatory amino-acids; [h-3]norepinephrine release; n-methyl-d-aspartate; nmda-binding-sites; norepinephrine release; slice
Developmental alterations in N-methyl-D-aspartate (NMDA)-stimulated [H-3]norepinephrine release from rat brain cortical and hippocampal slices were studied. NMDA (10-1000 muM) resulted in a concentration-dependent increase in [H-3]norepinephrine efflux; maximal responses (% released) in the cortex were: (1.53 +/- 0. 12, 3.68 +/- 0.20, 2.94 +/- 0.20, 4.60 +/- 0.28 and 5.28 +/- 0.33) and the hippocampal responses were: (1.90 +/- 0.18, 3.84 +/- 0.23, 3.60 +/- 0.28, 5.16 +/- 0.38 and 5.81 +/- 0.45) at varying postnatal ages (1, 7, 14, 21 and 90 days) respectively. Cortical tissue from 7-day-old pups exhibited a transient increase in maximal efflux and a decrease in EC50. These results indicated that developmental alterations in the NMDA receptor appear to be translated into differences in NMDA stimulated [H-3]norepinephrine release.
Brown L M
Neuroscience Letters
1993
1993-05
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0304-3940(93)90167-j" target="_blank" rel="noreferrer noopener">10.1016/0304-3940(93)90167-j</a>
CHOLESTEROL 7-ALPHA-HYDROXYLASE IS UP-REGULATED BY THE COMPETITIVE INHIBITOR 7-OXOCHOLESTEROL IN RAT-LIVER
Biochemistry & Molecular Biology; expression; cloning; dietary-cholesterol; purification; messenger-rna; circadian-rhythm; reductase; microsomes; sequence; serum-cholesterol
Rats of the Sprague-Dawley strain were infused intravenously with a fat emulsion (Intralipid, trademark of Kabi Pharmacia, Uppsala, Sweden) containing 7-oxocholesterol. This resulted in an increased cholesterol 7alpha-hydroxylase activity in liver microsomes as compared to controls and was accompanied by increased levels of cholesterol 7alpha-hydroxylase mRNA and microsomal cholesterol 7alpha-hydroxylase protein. Rats were also fed a cholestyramine-supplemented diet and infused with 7-oxocholesterol. These animals excreted about half as much bile acids in faeces as cholestyramine-fed controls. Addition of 7-oxocholesterol to liver microsomes from normal rats in amounts corresponding to those present in microsomes from 7-oxocholesterol-treated rats inhibited the cholesterol 7alpha-hydroxylase activity by about 75%. Cholesterol induced a type-I binding spectrum when added to a purified bacterial-expressed cholesterol 7alpha-hydroxylase (P-450c7DELTA2-24). 7-Oxocholesterol competitively inhibited the cholesterol binding spectrum, while 7beta-hydroxycholesterol did not interfere with binding of cholesterol to the enzyme. It is concluded that treatment with the competitive inhibitor 7-oxocholesterol leads to a reduced bile acid biosynthesis and, as a consequence of reduced bile acid inhibition, a compensatory increase in cholesterol 7alpha-hydroxylase synthesis. The high enzyme activity measured in microsomal preparations from 7-oxocholesterol-treated rats may be due to a continuous conversion of 7-oxocholesterol into less inhibitory metabolites, e.g. 7beta-hydroxycholesterol. The latter compound was found in high concentrations in liver microsomes from rats treated with 7-oxocholesterol. The physiological importance of these results is discussed in relation to the previous findings that 7-oxocholesterol is accumulated in liver after cholesterol feeding and that 7-oxocholesterol is formed from cholesterol during lipid peroxidation.
Breuer O; Sudjanasugiaman E; Eggertsen G; Chiang J Y L; Bjorkhem I
European Journal of Biochemistry
1993
1993-08
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1111/j.1432-1033.1993.tb18082.x" target="_blank" rel="noreferrer noopener">10.1111/j.1432-1033.1993.tb18082.x</a>
ELEVATION OF CARDIAC-OUTPUT AND OXYGEN DELIVERY IMPROVES OUTCOME IN SEPTIC SHOCK
Respiratory System; General & Internal Medicine
Bredle D L
Chest
1993
1993-04
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1378/chest.103.4.1311c" target="_blank" rel="noreferrer noopener">10.1378/chest.103.4.1311c</a>
RELATION OF DEPRESSION TO HOSPITALIZATION OR MORTALITY FROM INJURIES IN THE 1ST NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY (NHANES-I) COHORT
Environmental & Occupational Health; Public
Bourguet C C; Logue E E; McCord G W
American Journal of Epidemiology
1993
1993-10
Journal Article or Conference Abstract Publication
n/a
ANTIGENIC-STIMULATION AND MULTIPLE-MYELOMA - A PROSPECTIVE-STUDY
inflammation; cancer; association; follow-up; leukemia; Oncology; rheumatoid-arthritis; risk; lymphoma; allergens; Allergy; antigens; autoimmune diseases; bacterial infections; multiple myeloma (etiology); plasma-cell; prospective studies
Background. A causal relationship between antigenic conditions and multiple myeloma was suggested by case reports. Although controlled studies identified associations with individual conditions, they failed to give overall support to the hypothesis. Using a prospective cohort representative of the U.S. population, the authors hypothesized that immune-stimulating conditions are a risk factor for multiple myeloma. Methods. The First National Health and Nutrition Examination Survey cohort of 14,407 persons were interviewed from 1971 to 1975 by the National Center for Health Statistics. Vital status with cause of death and hospitalizations were ascertained from 1982 to 1985 and in 1986. From the initial questionnaire, four risk factors were constructed: allergies (asthma, hives, hay fever, food allergies, and other allergies); autoimmune conditions (arthritis, thyroid disease and/or medication, rheumatic fever, diabetes, pernicious anemia); chronic bacterial conditions (chronic bronchitis or emphysema, chronic cough, tuberculosis, ulcers); and inflammatory conditions (gout, gallstones, recurrent or chronic enteritis, pleurisy). Results. Eighteen multiple myeloma (MM) cases were documented. The rate ratio (RR) of MM increased as the number of reported inflammatory conditions increased (one condition, RR = 2.0, 95% confidence interval [CI] = 1.2-3.3; 2 or more conditions, RR = 4.3, 95% CI = 1.5-12.4). The RR of myeloma also increased (P = 0.0002) with time since start of inflammatory conditions (RR = 1.6 for every 10 years of exposure). When cases were restricted to those with more than five years of follow-up, myeloma risk increased with the number of inflammatory conditions (two conditions, RR = 4.6, 95% CI = 1.5-13.8). Conclusions. Although the number of cases is small and exposure may be misclassified, the prospective nature of the study design strengthens the results of the study.
Bourguet C C; Logue E E
Cancer
1993
1993-10
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1002/1097-0142(19931001)72:7%3C2148::aid-cncr2820720714%3E3.0.co;2-q" target="_blank" rel="noreferrer noopener">10.1002/1097-0142(19931001)72:7%3C2148::aid-cncr2820720714%3E3.0.co;2-q</a>
LEFT-VENTRICULAR DYSFUNCTION FOLLOWING MASSIVE SYMPATHETIC NERVOUS-SYSTEM (SNS) ACTIVATION IS ATTENUATED BY CAPTOPRIL
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Bosso F J; Scott W M; Senanayake P; Pilati C F
Faseb Journal
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
FURTHER PSYCHOMETRIC EVALUATIONS OF A CLASS-RANKING MODEL AS A PREDICTOR OF GRADUATES CLINICAL COMPETENCE IN THE 1ST YEAR OF RESIDENCY
Health Care Sciences & Services; Education & Educational Research; schools; deans letters; directors
Purpose. To investigate further the psychometrics of a class-ranking model in which a weight of one-third was assigned to performance measures in basic sciences and a weight of two-thirds to ratings on six core clerkships. Method. The first part of the study involved 215 graduates of Jefferson Medical College who-based on the ranking model-had been in the top and bottom quarters of the classes of 1991 and 1992. Six faculty, who did not know the graduates' ranks but were familiar with their performances and characteristics, were asked to judge the graduates' potentials to become competent physicians. The graduates' ranks according to the model were then compared with the ratings they received from the faculty. The second part of the study investigated whether there was a linear relationship between class ranks and ratings of postgraduate competence, by using directors' ratings of the data-gathering skills of 598 graduates (1986-1990) at the end of their first year of residency. Results. A concordance rate of 85% was obtained between the graduates' ranks and the ratings they received from the medical school faculty, which supports the criterion-related validity of the ranking model. In addition, class ranks were linearly related to ratings of postgraduate competence. However, women and graduates who had been low achievers in medical school were less likely to have given permission for collecting postgraduate ratings, which led to range restriction and a possible underestimation of the validity of the model. Conclusion. The psychometric evidence supports the class-ranking model, but other schools should exercise caution in employing the model until they accumulate evidence from data obtained from their own students.
Blacklow R S; Goepp C E; Hojat M
Academic Medicine
1993
1993-04
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1097/00001888-199304000-00017" target="_blank" rel="noreferrer noopener">10.1097/00001888-199304000-00017</a>
VISUAL DEPRIVATION DECREASES LONG-TERM POTENTIATION IN RAT VISUAL CORTICAL SLICES
cortex; rat; plasticity; depression; period; Neurosciences & Neurology; pathways; induction; long-term potentiation; organization; nmda receptors; evoked-potentials; visual cortex; critical; current source density; dark rearing; monocular deprivation; source density analysis
A major finding in the visual plasticity literature is that visual deprivation is effective only during an early 'sensitive' period, which is lengthened by dark rearing. Unresolved is whether the visual cortex is in a normally plastic state prior to light stimulation. This cannot be addressed using paradigms employing light exposure to assess plasticity. Several developmental studies have investigated a plastic phenomenon termed long-term potentiation (LTP) in slices from cat (J. Neurophysiol., 59 (1988) 124-141) and rat (Brain Res., 439 (1988) 222-229) visual cortex. Susceptibility to the induction of LTP parallels the period of sensitivity to visual deprivation. This suggests that slices can be used to assay visual cortical plasticity, avoiding light exposure. In the present study, field potentials were recorded from slices of the primary visual cortices of dark-reared (DR) and control (CONT) Long Evans hooded rats (17 to 21 days). Field potential profiles recorded before and 90 min following tetanic electrical stimulation were subjected to current source density analysis, yielding extracellular current sink amplitudes. Tetanus resulted in LTP in both CONT and DR slices, but DR slices were significantly less potentiated. These results indicate that the primary visual cortex of DR animals is not fully plastic, indicating a role for light stimulation in inducing visual cortical plasticity.
Berry R L; Perkins A T; Teyler T J
Brain Research
1993
1993-11
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1016/0006-8993(93)90943-h" target="_blank" rel="noreferrer noopener">10.1016/0006-8993(93)90943-h</a>
MULTIORGAN PROCUREMENT FROM A VICTIM OF CYANIDE POISONING - A CASE-REPORT AND REVIEW OF THE LITERATURE
Surgery; Transplantation; Immunology; donor
Barkoukis T J; Sarbak C A; Lewis D; Whittier F C
Transplantation
1993
1993-06
Journal Article or Conference Abstract Publication
n/a
MITRAL-VALVE DISEASE-ASSOCIATED WITH LONG-TERM ERGOTAMINE USE
General & Internal Medicine
Austin S M; Elhayek A; Comianos M; Tamulonis D J
Southern Medical Journal
1993
1993-10
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1097/00007611-199310000-00024" target="_blank" rel="noreferrer noopener">10.1097/00007611-199310000-00024</a>
DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS IN MEROITIC NUBIANS FROM SEMNA SOUTH, SUDAN
aging; ankylosing-spondylitis; Anthropology; arthritis; dish; Evolutionary Biology; forestiers disease; population; vertebral column
The paleopathological study of human osteological remains from the site of Semna South, of northern Sudan, revealed that about thirteen percent of this ancient Nubian population had diffuse idiopathic skeletal hyperostosis (DISH). As in modern cases, males were more affected than females. Two thousand years ago, ancient Nubian males had the same spinal problems elderly men have today. (C) 1993 Wiley-Liss. inc.
Arriaza B T; Merbs C F; Rothschild B M
American Journal of Physical Anthropology
1993
1993-11
Journal Article or Conference Abstract Publication
<a href="http://doi.org/10.1002/ajpa.1330920302" target="_blank" rel="noreferrer noopener">10.1002/ajpa.1330920302</a>
CATECHOLAMINE CARDIOMYOPATHY - MYOCARDIAL DEPRESSION DOES NOT CORRELATE WITH HISTOPATHOLOGY
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Allman F D; Bosso F J; Herold W; Pilati C F
Faseb Journal
1993
1993-02
Journal Article or Conference Abstract Publication
n/a
EYELID DISORDERS - RECOGNIZING PATHOLOGICAL-CHANGES IN THE OLDER PATIENT
Geriatrics & Gerontology
The eyelids provide a vital function in protecting and cleansing the eye but are also the source of numerous disorders and complaints in your older patients. Clinically, the most important of these problems are suspicious lid lesions that may harbor malignancy, neurologic disorders, and structural malpositions that cause poor lid function and may damage the globe. Many of these disorders require prompt evaluation and often referral to an ophthalmologist for surgical management. Less serious problems such as blepharitis can often be treated in the primary care office setting.
Zucker J L
Geriatrics
1993
1993-09
Journal Article
n/a
PHYSICOCHEMICAL CHARACTERIZATION OF AQUEOUS LIPID PHASES OF RELEVANCE TO INTESTINAL FAT DIGESTION AND ABSORPTION - A H-2 NMR AND X-RAY-DIFFRACTION STUDY
Biophysics
Westerman P W; Chen L
Biophysical Journal
1993
1993-02
Journal Article
n/a
PHYSICOCHEMICAL CHARACTERIZATION OF AQUEOUS LIPID PHASES OF RELEVANCE TO INTESTINAL FAT DIGESTION AND ABSORPTION - A H-2 NMR-STUDY
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Westerman P W
Faseb Journal
1993
1993-04
Journal Article
n/a
SPONDYLITIS DUE TO GROUP G-STREPTOCOCCUS - REPLY
osteomyelitis; Rheumatology
Watanakunakorn C; Burkert T
Journal of Rheumatology
1993
1993-04
Journal Article
n/a
THE HUMAN CYTOCHROME-B-5 GENE AND 4 OF ITS PSEUDOGENES ARE LOCATED ON CHROMOSOME 18Q23, 14Q31-32.1, 20P11.2, 14Q11.2-13 AND 14, RESPECTIVELY
Genetics & Heredity
Steggles A W; Giordano S J; Yoo M; Overhauser J; Bhatt M; Ward D
American Journal of Human Genetics
1993
1993-09
Journal Article
n/a
THE SIGNIFICANCE OF ENTHESOPATHY AS A SKELETAL PHENOMENON
ankylosing spondylitis; arthropathy; calcium pyrophosphate; crystal deposition disease; defleshed bones; deposition disease; enthesitis; erosive arthritis; lesions; rheumatoid-arthritis; rheumatoid-arthritis; Rheumatology; spondyloarthropathies
Enthesophytes and enthesopathy, while easy to define, represent a phenomenon of unclear clinical significance. As the high frequency in skeletal populations suggests that enthesopathy may not be disease-specific, the nature of the reaction was assessed in 872 individuals from a representative skeletal population, subdivided into groups characterized by the presence or absence of rheumatoid arthritis, spondyloarthropathy, calcium pyrophosphate deposition disease and diffuse idiopathic skeletal hyperostosis (DISH). Achilles, plantar fascia, patellar and iliac crest entheses were examined for evidence of calcific overgrowth or ''erosions.'' Enthesophytes were found to be a phenomenon of aging in individuals, and unrelated to the presence of inflammatory arthritis or DISH. The frequency increased with age, independent of sex or the site examined, plateauing infrequency after age 60. Enthesophytes in individuals under age 60 were usually unrelated to any underlying disorder. The absence of effect of underlying forms of arthritis on the frequency of enthesophytes at the patellar, Achilles and plantar sites suggests that mechanical factors outweigh the ''enthesis calcifying '' impact of such disorders as spondyloarthropathy, calcium pyrophosphate deposition disease and DISH. Individuals with rheumatoid arthritis, however, manifested a less severe iliac crest enthesial reaction, in keeping with the minimal reactive new bone formation characteristic of its erosions. Analysis of Achilles, plantar, and patellar enthesial reactions as a function of underlying inflammatory arthritis or DISH also revealed no significant variation with the underlying process. Cortical discontinuity at enthesial sites was a relatively infrequent phenomenon. While calcaneal discontinuities were originally thought to be erosive in nature, these observations suggest the possibility of tendon avulsion injuries.
Shaibani A; Workman R; Rothschild B M
Clinical and Experimental Rheumatology
1993
1993-07
Journal Article
n/a
CHRONIC SPONTANEOUS EXERCISE ATTENUATED CARDIOPULMONARY REFLEX INHIBITION OF LUMBAR SYMPATHETIC-NERVE ACTIVITY
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Scislo T; DiCarlo S E
Faseb Journal
1993
1993-02
Journal Article
n/a
ZYGAPOPHYSEAL AND COSTOVERTEBRAL COSTOTRANSVERSE JOINTS - AN ANATOMIC ASSESSMENT OF ARTHRITIS IMPACT
costovertebral joint; defleshed bones; diffuse idiopathic skeletal hyperostosis; enthesopathy; erosion; erosive arthritis; fusion; involvement; osteoarthritis; pathogenesis; rheumatoid-arthritis; rheumatoid-arthritis; Rheumatology; spine; spondyloarthropathy; zygapophyseal joint
Sanzhang C; Rothschild B M
British Journal of Rheumatology
1993
1993-12
Journal Article
n/a
BRITTLE DIABETES TREATED WITH INTENSIFIED THERAPY AND A POCKET INSULIN DOSAGE COMPUTER
adjustment; brittle diabetes; Endocrinology & Metabolism; hypoglycemia; intelligence; intensive insulin therapy; medical artificial; medical computers; Nutrition & Dietetics; optimum diabetes therapy; quality-of-life; uncontrolled diabetes
Brittle diabetes is a therapeutic challenge. The first experience with a pocket Insulin Dosage Computer (IDC(TM)) in brittle diabetes was conducted in the form of a clinical N-of-1 trial. After intensified conventional therapy (ICT) the patients used the insulin dosage computer (ICT+IDC), and then the IDC was withdrawn (ICT-IDC). During ICT+IDC therapy, weekly pre-prandial mean blood glucose levels, glycohemoglobin levels and quality of life were all significantly improved. Hypoglycemia was eliminated. When the IDC was withdrawn (ICT-IDC), metabolic control deteriorated. The 2-tailed p value was used for statistical analysis.
Sakkal S
Diabetes Nutrition & Metabolism
1993
1993-04
Journal Article
n/a
SPONDYLOARTHROPATHY IN URSIDAE - A SEXUALLY-TRANSMITTED DISEASE
erosive arthritis; Science & Technology - Other Topics
Rothschild B M; Wang X M; Cifelli R
Research & Exploration
1993
1993
Journal Article
n/a
SACROILIAC ARTHROSCOPY - A NEW VALIDATION APPROACH TO THE DIAGNOSIS OF SPONDYLOARTHROPATHY
Rheumatology
Rothschild B M; Poteat B; Williams E; Woods R J; Pascale P J
Arthritis and Rheumatism
1993
1993-05
Journal Article
n/a
PARADOX OF EROSIVE ARTHRITIS IN NEW-WORLD MONKEYS - COLLAGEN-INDUCED VERSUS NATURALLY-OCCURRING SPONDYLOARTHROPATHY
Rheumatology
Rothschild B M; Woods R J; Rothschild C
Arthritis and Rheumatism
1993
1993-05
Journal Article
n/a
GEOGRAPHIC-DISTRIBUTION OF CALCIUM PYROPHOSPHATE (CPPD) DEPOSITION DISEASE IN PRE-COLUMBIAN NORTH-AMERICA - INDEPENDENT VALIDATION OF CPPD CRITERIA
arthritis; arthropathy; calcium pyrophosphate deposition disease; chondrocalcinosis; epidemiology; osteoarthritis; osteoarthritis; paleopathology; Pathology; Rheumatology
Calcium pyrophosphate deposition disease (CPPD), a form of crystalline arthritis, has a unique distribution in the Early to Middle Archaic Periods (3000 to 8000 years before the present) of North America, contrasting with the generalized geographic distribution of osteoarthritis. Incursion of CPPD into specific regions suggests possible migration patterns. The disparate geographic distribution of CPPD and osteoarthritis provide independent verification of the validity of diagnostic criteria utilized for the identification of CPPD.
Rothschild B M; Woods R J
Clinical and Experimental Rheumatology
1993
1993-05
Journal Article
n/a
ARTHRITIS OF THE SPONDYLOARTHROPATHY VARIETY IN CALLITHRIX-JACCHUS
defleshed bones; erosive arthritis; primate; reactive arthritis; rheumatoid-arthritis; skeletal pathology; spondyloarthropathy; Veterinary Sciences; Zoology
Sixty skeletons of Callithrix jacchus were examined to identify spondy-loarthropathy. Erosive disease in Callithrix was confirmed as spondy-loarthropathy on the basis of diagnostic sacroiliac erosions, syndesmophyte formation, and the nature and distribution of the peripheral joint erosions
Rothschild B M
Journal of Medical Primatology
1993
1993-07
Journal Article
n/a
EVOLUTION OF TECHNIQUES OF STAPEDECTOMY FROM THE TOTAL STAPEDECTOMY TO THE SMALL FENESTRA STAPEDECTOMY
Otorhinolaryngology
Rizer F M; Lippy W H
Otolaryngologic Clinics of North America
1993
1993-06
Journal Article
n/a