Browse Items · NEOMED Bibliography Database

Raphe nuclei in three cartilaginous fishes, Hydrolagus colliei, Heterodontus francisci, and Squalus acanthias.

The vertebrate reticular formation, containing over 30 nuclei in mammals, is a core brainstem area with a long evolutionary history. However, not all reticular nuclei are equally old. Nuclei that are widespread among the vertebrate classes are…

Tags: *Biological Evolution, 1995, Animals, Cruce W L, Dogfish/*anatomy & histology/metabolism, Elasmobranchii/*anatomy & histology/metabolism, Enkephalin, Immunohistochemistry, Leucine/analysis, Raphe Nuclei/*anatomy & histology/chemistry, Serotonin/analysis, Sharks/*anatomy & histology/metabolism, Stuesse D C, Stuesse S L, The Journal of comparative neurology

The isolation and characterization of the human cytochrome b5 gene.

From a series of lambda and cosmid libraries, we isolated DNA sequences corresponding to the complete coding region for the human cytochrome b5 (CYB5) gene. The overall gene organization was the same as the bovine and rabbit CYB5 genes. One cosmid…

Binding of sequence-specific proteins to the 3'-untranslated region of vasoactive intestinal peptide mRNA.

Multimeric AUUUA elements in an AU-rich 3'-untranslated region (3'-UTR) have been shown to confer message instability to numerous ephemeral transcripts through the formation of RNA-protein complexes. We show here that the 3'-UTR of VIP mRNA, which…

Uterine cervix adenocarcinoma with both human papillomavirus type 18 and tumor suppressor gene p53 mutation from a woman having an intact hymen.

Human papillomavirus (HPV) type 18 DNA was found in an aggressively invasive adenocarcinoma tumor from a woman who had an intact hymen and denied any prior sexual intercourse. The viral DNA was detected within the tumor tissue by polymerase chain…

The cost of laparoscopic versus open cholecystectomy in a community hospital.

This retrospective study reviewed the hospital and professional costs, charges, and reimbursements for laparoscopic cholecystectomy (lap chole) and open cholecystectomy (open chole) and compared the two procedures. There was no significant difference…

Laparoscopic hernia repair. Three-year experience.

The basis of laparoscopic transabdominal preperitoneal repair (LTPR) of herniae rests upon the utilization of a prosthetic screen to cover hernia defects. Preperitoneal prosthetic screen interposition reproduces the effect of the inguinal shutter…

Tags: 1995, 80 and over, Adolescent, Adult, Aged, Female, Follow-Up Studies, Hernia, Humans, Inguinal/*surgery, Kavic M S, Laparoscopy/*methods, Male, Middle Aged, Postoperative Complications, Prostheses and Implants, Reoperation, Surgical endoscopy

A block in glycoprotein processing correlates with small plaque morphology and virion targetting to cell-cell junctions for an oral and an anal strain of herpes simplex virus type-1.

The characteristics of two clinical isolates of HSV-1 obtained from an oral (424) and an anal (490) lesion were compared with the highly passaged KOS strain. In contrast to KOS, the clinical isolates produced small plaques, were more cell-associated…

The discriminative properties of the D1 dopamine agonist dihydrexidine in the rat.

The objective of this study was to train rats to discriminate the interoceptive stimuli produced by a selective dopamine D1 agonist. Fourteen male Sprague-Dawley rats acquired the discrimination of the fully effective, high potency, D1 agonist…

Tags: 1995, Amphetamine/pharmacology, Animals, Apomorphine/pharmacology, Benzazepines/pharmacology, Cocaine/pharmacology, Discrimination (Psychology), Dopamine Agonists/pharmacology, Dopamine D1/*agonists, Dose-Response Relationship, Drug, Male, Phenanthridines/*pharmacology, Psychopharmacology, Rats, Receptors, Schechter M D, Sprague-Dawley

Prediction of cardiac death in patients with a very low ejection fraction after myocardial infarction: a Cardiac Arrhythmia Suppression Trial (CAST) study.

The Cardiac Arrhythmia Suppression Trial (CAST) database was analyzed with a Cox proportional hazards regression model to predict the mortality of patients with very poor left ventricular systolic function (ejection fraction \textless or = .20).…

Genetic selection for nicotine activity in mice correlates with conditioned place preference.

Genetically heterogenous stock (HS) mice are being used to develop lines which have differential locomotor response to subcutaneously administered (0.75 mg/kg) nicotine. These groups of nicotine-depressed, nicotine-activated or randomly bred control…

Tags: *Conditioning, 1995, Analysis of Variance, Animals, European journal of pharmacology, Female, Inbred Strains, Male, Meehan S M, Mice, Movement/*drug effects, Nicotine/*pharmacology, Operant, Schechter J B, Schechter M D

Blockade of cocaine-induced conditioned place preference: relevance to cocaine abuse therapeutics.

Conditioned place preference/aversion testing is a behavioral method believed capable of measuring the affective (positive, neutral or negative) properties of psychoactive drugs. Cocaine injections in rats reliably produces a positive place…

Tags: 1995, Animals, Calcagnetti D J, Calcium Channel Blockers/pharmacology/therapeutic use, Cocaine/*antagonists & inhibitors, Conditioning (Psychology)/*drug effects, Humans, Keck B J, Life sciences, Narcotic Antagonists/pharmacology, Quatrella L A, Schechter M D, Serotonin Antagonists/pharmacology, Substance-Related Disorders/*drug therapy

Discriminative stimulus properties of isradipine: effect of other calcium channel blockers.

This study constitutes the first report of a calcium channel blocker used as a drug capable of controlling differential responding in a drug-discrimination paradigm. Male Sprague-Dawley rats were trained to discriminate between intraperitoneally…

Tags: 1995, Animals, Calcium Channel Blockers/*pharmacology, Conditioning, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Generalization, Isradipine/*pharmacology, Male, Operant/*drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Sprague-Dawley, Stimulus/*drug effects

Cocaethylene produces discriminative stimulus properties in the rat: effect of cocaine and ethanol coadministration.

Experimentally naive Sprague-Dawley male rats were trained to discriminate the interoceptive stimulus cues produced by either 10.0 mg/kg cocaine or 10.0 mg/kg cocaethylene from their saline vehicles. Although it required more sessions to train the…

Tags: 1995, Animals, Cocaine/*analogs & derivatives/pharmacokinetics/*pharmacology, Discrimination (Psychology)/*drug effects, Dose-Response Relationship, Drug, Ethanol/pharmacokinetics/*pharmacology, Male, Pharmacology, biochemistry, and behavior, Rats, Reinforcement Schedule, Schechter M D, Sprague-Dawley

Serotonergic mediation of cocaine seizures in mice.

We used genetically heterogeneous HS mice to investigate the effects of drugs that alter brain concentrations of serotonin on cocaine-induced convulsions and lethality. The racemer of fenfluramine, which increases synaptic serotonin, was…

Role of dopamine D1 receptors in cocaine lethality.

One group of heterogeneously bred HS mice was assigned to test coadministration of the selective D1 antagonist SCH 23390 with a dose of cocaine (95 mg/kg) that was observed to produce 80% lethality, whereas a second group was tested by cotreatment…

Tags: 1995, Animals, Benzazepines/pharmacology, Cocaine/*toxicity, Dopamine Agonists/pharmacology, Dopamine D1/agonists/antagonists & inhibitors/*drug effects, Female, Inbred Strains, Lethal Dose 50, Male, Meehan S M, Mice, Pharmacology, biochemistry, and behavior, Phenanthridines/pharmacology, Receptors, Schechter M D, Sex Characteristics

Cocaethylene produces conditioned place preference in rats.

The ability of cocaethylene to produce either a conditioned place preference or a conditioned place aversion was tested in rats. Twelve male rats were administered 10 mg/kg cocaethylene and confined to their nonpreferred side of the conditioned place…

Tags: 1995, Animals, Avoidance Learning/drug effects, Cocaine/*analogs & derivatives/pharmacology, Conditioning, Discrimination (Psychology)/drug effects, Male, Motor Activity/*drug effects, Operant/*drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Sprague-Dawley

The lethal effects of ethanol and cocaine and their combination in mice: implications for cocaethylene formation.

The HS line of mice was used to determine the LD50 values for cocaine and ethanol, as well as for cocaethylene, the enzymatic product of their coadministration. The LD50 of cocaethylene was found to be significantly lower than that of cocaine, and…

Tags: 1995, Animals, Central Nervous System Depressants/*toxicity, Cocaine/*analogs & derivatives/metabolism/toxicity, Dopamine Uptake Inhibitors/*toxicity, Dose-Response Relationship, Drug, Drug Interactions, Ethanol/*toxicity, Female, Lethal Dose 50, Male, Meehan S M, Mice, Pharmacology, biochemistry, and behavior, Schechter M D, Sex Characteristics

Synaptic plasticity in the hippocampal slice: functional consequences.

There are 3 known forms of synaptic plasticity at CNS synapses: long-term potentiation (LTP) mediated by NMDA receptor activation, LTP mediated by voltage-dependent calcium channel (VDCC) activation, and long-term depression (LTD) mediated by the…

Tags: 1995, Animals, Calcium Channels/physiology, Cavus I, Coussens C, Hippocampus/*physiology, Journal of neuroscience methods, Long-Term Potentiation/physiology, Models, N-Methyl-D-Aspartate/physiology, Neurological, Neuronal Plasticity/*physiology, Receptors, Synapses/*physiology, Teyler T J

Clinical pearl: systemic antifungal drugs and drug interactions.

Tags: 1995, Antifungal Agents/*pharmacology/therapeutic use, Brodell R T, Drug Interactions, Elewski B E, Humans, Journal of the American Academy of Dermatology

Surgical pearl: treatment of subungual splinters.

Tags: 1995, Brodell R T, Carbon Dioxide, Fingers/*surgery, Foreign Bodies/*surgery, Humans, Journal of the American Academy of Dermatology, Laser Therapy, Miller M A, Nails/*surgery

Spontaneous vertebral artery dissection as a complication of autosomal dominant polycystic kidney disease.

Autosomal dominant polycystic kidney disease (ADPKD) may be associated with a variety of cardiovascular complications, including intracranial saccular aneurysms. In ADPKD, intracranial saccular aneurysms tend to rupture more frequently and earlier…

Tags: *Vertebral Artery, 1995, Adult, American journal of kidney diseases : the official journal of the National Kidney Foundation, Aneurysm, Autosomal Dominant/*complications/genetics, Department of Internal Medicine, Dissecting/*genetics, Humans, Intracranial Aneurysm/*genetics, Larranaga J, Male, NEOMED College of Medicine, Pedigree, Polycystic Kidney, Rutecki G W, Whittier F C

Heart specialists' art of care.

Primary care physicians who encourage patients to interact in the medical interview receive high ratings of patient satisfaction with art of care. To determine if this finding holds true in specialty medicine, we designed a two-factor [art of care…

Tags: *Patient Satisfaction, *Physician-Patient Relations, 1995, Blixt S L, Cardiology/*standards, Humans, Quality of Health Care, Social science & medicine (1982), Speight J D, Thoracic Surgery/*standards

Scopolamine-physostigmine combination does not substitute for nicotine.

1. Male Sprague-Dawley rats were trained to discriminate 0.4 mg/kg nicotine subcutaneously administered from its saline vehicle in a food-motivated operant discrimination task. Once trained, the discriminative performance was observed to be…

Expression of alpha-cardiac myosin heavy chain in normal and denervated rat muscle spindles.

Whether any fibers in rat hindlimb muscles express alpha-cardiac myosin heavy chain (MHC) is uncertain. Expression of alpha-cardiac MHC mRNA and the polypeptide for which it codes were examined in control and denervated rat muscle spindles using in…

Tags: 1995, Animals, Denervation, In Situ Hybridization, McWhorter D L, Messenger/metabolism, Muscle Spindles/*metabolism/physiology, Myocardium/*metabolism, Myosin Heavy Chains/*metabolism, Neuroscience letters, Rats, RNA, Signs S A, Sprague-Dawley, Time Factors, Walro J M, Wang J

A lack of supersensitivity to opioid receptor agonists following chronic spinal opioid receptor antagonist administration in the rat.

1. Male Sprague-Dawley rats were chronically tested with intrathecal (i.t.) receptor selective opioid antagonists to determine if antinociceptive supersensitivity developed to selective i.t. opioid receptor agonists. 2. A subcutaneously implanted…

Premorbid behaviors produced by cocaine, ethanol and cocaethylene in the mouse.

1. The premorbid behaviors produced by the administration of cocaine, ethanol, their combination, as well as a metabolite produced by their co-administration, viz. cocaethylene, were defined, determined and quantified in the HS strain of mice. 2. The…

Tags: 1995, Animal/*drug effects, Animals, Behavior, Cocaine/*analogs & derivatives/*toxicity, Dose-Response Relationship, Drug, Ethanol/*toxicity, Female, General pharmacology, Lethal Dose 50, Male, Meehan S M, Mice, Schechter M D

Pentobarbital differentially inhibits N-methyl-D-aspartate and kainate-stimulated [3H]noradrenaline overflow in rat cortical slices.

1. This study examined the ability of pentobarbital to inhibit NMDA and kainate-stimulated [3H]noradrenaline ([3H]NA) overflow in rat brain cortical slices. 2. Pentobarbital inhibited NMDA-evoked [3H]NA overflow at 100 microM and greater and…

Tags: *Excitatory Amino Acid Agonists, 1995, Adrenergic alpha-Agonists/metabolism, Animals, Brown L M, GABA Modulators/*pharmacology, General pharmacology, Kainic Acid/*antagonists & inhibitors, Male, N-Methylaspartate/*antagonists & inhibitors, Norepinephrine/metabolism, Pentobarbital/*pharmacology, Prefrontal Cortex/*drug effects, Rats, Sprague-Dawley

Combination-sensitive neurons in the inferior colliculus.

We examined whether neurons in the inferior colliculus of the mustached bat (Pteronotus parnellii) are combination sensitive, responding to both low- and high-frequency components of the bat's sonar signal. These neurons, previously reported in the…

Tags: 1995, Acoustic Stimulation, Animals, Auditory Cortex/metabolism, Chiroptera, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Doppler, Hearing research, Inferior Colliculi/*cytology/metabolism, Mittmann D H, NEOMED College of Medicine, Neurons/cytology/*physiology, Sound Localization, Transcranial, Ultrasonography, Wenstrup J J

Alcohol, drugs, and urban violence in a small city trauma center.

Substance abuse and urban trauma go hand in hand. But research focuses on large cities served by major academic medical centers. Do small cities face the same problems? Two hundred thirty-three urban trauma inpatients from a metro area of 250,000…

Cocaethylene-induced lethality in mice is potentiated by alcohol.

Mice of the heterogeneously bred HS line were concurrently administered intraperitoneal injections of either 95, 75, 60, or 48 mg/kg cocaethylene or 48, 38, or 30 mg/kg cocaethylene in conjunction with the non-lethal dose of 6.0 g/kg (20% w/v)…

Tags: 1995, Alcohol (Fayetteville, N.Y.), Animals, Cocaine/*analogs & derivatives/poisoning, Dose-Response Relationship, Drug, Drug Synergism, Ethanol/*pharmacology, Female, Inbred Strains, Lethal Dose 50, Male, Meehan S M, Mice, Schechter M D

MDMA (Ecstasy) substitutes for the ethanol discriminative cue in HAD but not LAD rats.

Selectively bred high- and low-alcohol-drinking (HAD/LAD) rats were trained to discriminate the interoceptive stimuli produced by IP-administered 600 mg/kg ethanol (10% w/v in a two-lever, food-motivated operant task. Once criterion discrimination…

A comparison of EMLA cream versus nitrous oxide for pediatric venous cannulation.

STUDY OBJECTIVE: To compare the analgesic and anxiolytic effects of nitrous oxide (N2O) when inhaled by face mask with those of a cutaneous application of a eutectic mixture of local anesthetics (EMLA) cream with lidocaine and prilocaine during…

Urothelial extension of Wilms tumor presenting as a prolapsing urethral mass.

We report a unique case of Wilms tumor presenting as a urethral mass in a patient with bilateral ureteral duplication. The prolapsing urothelial component was contiguous with the intrarenal Wilms tumor and consisted of fetal skeletal muscle free of…

Tags: 1995, Child, Female, Humans, Khoudary K P, Kidney Neoplasms/diagnosis/*pathology, Nasrallah P F, Preschool, Prolapse, Stanley K, The Journal of urology, Ureter/*abnormalities, Urethral Diseases/etiology, Urethral Neoplasms/complications/*secondary, Wilms Tumor/complications/diagnosis/*secondary

Antipseudomonal penicillins.

Antipseudomonal penicillins retain most of the antibacterial activity of penicillin and aminopenicillins. This group of penicillins has added activities against many gram-negative rods, including P. aeruginosa. Similar to the earlier penicillins,…

Tags: 1995, Anti-Bacterial Agents/pharmacology, Department of Internal Medicine, Drug Resistance, File T M Jr, Humans, Microbial, Microbial Sensitivity Tests, NEOMED College of Medicine, Penicillins/adverse effects/pharmacokinetics/*therapeutic use, Pseudomonas Infections/*drug therapy, Pseudomonas/*drug effects, Tan J S, The Medical clinics of North America

Ultrastructural changes of female Syrian hamster cystic duct epithelium as a result of sex steroid treatment.

In view of the lack of sufficient data regarding the morphology of the cystic duct and the extensive focus on the gallbladder, a preliminary examination of the cystic duct response to female sex steroid treatment was conducted to follow up a detailed…

Tags: 1995, Animals, Cell Nucleus/drug effects/ultrastructure, Combination, Cricetinae, Cystic Duct/*drug effects/*ultrastructure, Drug Therapy, Epithelium/drug effects/ultrastructure, Estrogens/*pharmacology, Female, Gallbladder/drug effects/ultrastructure, Gilloteaux J, Karkare S, Kelly T R, Medroxyprogesterone/*pharmacology, Mesocricetus, Tissue & cell

Morgagni hernia: incidental repair during laparoscopic cholecystectomy.

Anterior diaphragmatic hernias are a relatively rare finding. They can occur on either side of the body. We diagnosed and treated a Morgagni hernia during laparoscopic cholecystectomy.

Tags: *Laparoscopy, 1995, Cholecystectomy, Cholelithiasis/*complications/surgery, Diaphragmatic/complications/*surgery, Female, Ghani A, Hernia, Humans, Journal of laparoendoscopic surgery, Laparoscopic, Middle Aged, Smith J

Clostridium innocuum endocarditis.

Clostridial endocarditis is rare. We describe, to our knowledge, the first case of Clostridium innocuum endocarditis. The fatal case involved the tricuspid and pulmonary valves and was associated with multiple pulmonary emboli. We review the…

Tags: 1995, Adolescent, Bacterial/*etiology, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Clostridium Infections/*etiology, Cutrona A F, Department of Internal Medicine, Endocarditis, Fatal Outcome, Female, Heart Valve Diseases/etiology, Humans, Jagetia A, NEOMED College of Medicine, Pulmonary Embolism/etiology, Pulmonary Valve, Schaub C R, Tricuspid Valve, Watanakunakorn C

Pyoderma gangrenosum complicated by underlying osteomyelitis: successful treatment with radical surgical debridement and cyclosporine therapy.

Tags: 1995, Aged, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Cyclosporine/*therapeutic use, Debridement, Female, Follow-Up Studies, Humans, Leg Ulcer/complications/surgery/*therapy, Osteomyelitis/*complications/therapy, Pseudomonas Infections/*complications/therapy, Pyoderma Gangrenosum/complications/surgery/*therapy, Signs D J, Wagner D S

Reduction mammaplasty: an outcome analysis.

Reduction mammaplasty is usually performed to relieve painful symptoms and physical signs of macromastia. Justification for reduction mammaplasty should be based on the probability of relieving these clinical signs and symptoms. This retrospective…

Tags: *Mammaplasty/adverse effects, 1995, Adolescent, Adult, Aged, Annals of plastic surgery, Dabbah A, Fat Necrosis/etiology, Female, Humans, Lehman J A Jr, Middle Aged, Parker M G, Retrospective Studies, Tantri D, Treatment Outcome, Wagner D S

A required clerkship in community medicine.

Tags: *Clinical Clerkship, 1995, Academic medicine : journal of the Association of American Medical Colleges, Blacklow R S, Boex J R, Community Medicine/*education, Department of Family & Community Medicine, Humans, Keck C W, NEOMED College of Medicine

Browse Items (196 total)