Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…
Determination of the etiologic pathogens of community-acquired pneumonia has been problematic because of the lack of reliable rapid laboratory diagnostic tools as well as the controversy concerning diagnostic criteria. In the studies reviewed here, a…
Drug-induced acute tubular necrosis is a primary cause of acute renal failure (ARF); it may result from the use of such agents as aminoglycosides, amphotericin B, and radilocontrast media. To reduce the risk of aminoglycoside toxicity, prescribe the…
Angiotensin-converting enzyme (ACE) inhibitors and NSAIDs are among the drugs most commonly associated with acute renal failure (ARF). Patients at risk for ACE inhibitor-induced ARF include those with congestive heart failure (CHF) or compromised…
The authors argue for the extension of mandatory treatment to persons gravely disabled by substance abuse. The problem is examined from ideological, clinical, legal, economic, and ethical perspectives.
OBJECTIVES: To determine the accuracy and cost-effectiveness of nuclear scintigraphy for the diagnosis and localization of gastrointestinal (GI) bleeding and to determine whether nuclear scintigraphy accurately predicts the results of angiography.…
A method of evaluating trend (positive or negative) in 2 x K ordered tables is suggested for cases in which the scores for the first (K-1) categories are known a priori but the score for the last category is not known. Such a category is termed as…
The surface epithelium of 28 gallbladders removed during elective cholecystectomies and pathology collection was studied ultrastructurally. Focusing on 10 of the 28 cases that were diagnosed as cholecystitis, we found that the epithelium displayed…
We evaluated the ability of canine isolated nonperfused lung lobes to absorb fluid from their air spaces by simultaneously measuring alveolar liquid clearance (ALC) in three lobes removed from the same dog. Autologous plasma was instilled in the air…
Readiness for making educational and vocational choices plays a crucial role in career decision-making (Super, 1955). The present study examined (a) personality and role correlates of career choice readiness and (b) rates of change in career choice…
We previously reported a strain-related difference in basal 3 beta-hydroxysteroid dehydrogenase-isomerase (3 beta HSD) activity in response to testosterone in cultured Leydig cells. The data suggested that the response to testosterone was androgen…
OBJECTIVE: To make clinically relevant recommendations for electrocardiogram (ECG) testing among psychiatric patients, the study examined the practice of ordering ECGs for this population. METHODS: The records of 4,045 patients consecutively admitted…
BACKGROUND: Despite anecdotal evidence of a possibility of decreased effectiveness of oral contraceptives (OCs) with some antibiotics, it is not known whether antibiotic use in dermatologic practices engenders any increased risk of accidental…
In the present study, 1,869 skulls from the Hamann-Todd Collection were examined (macroscopically and by radiographs) for closure of the petroexoccipital articulation (jugular synchondrosis). The results demonstrated that the petroexoccipital…
The controversy over the reliability of ectocranial suture status (open vs. closed) as an age estimation stimulated the pursuit of Meindl and Lovejoy's suggestion (Meindl and Lovejoy [1985]Am. J. Phys. Anthropol. 68:57-66) for large scale analysis.…
The present study discusses in detail the osteological changes associated with sickle cell anemia in children and their importance in differential diagnosis. Posterior calcaneal and specific articular surface disruptive metacarpal lesions are…
Ethical issues in the clinical arena have received significant attention during the past few decades. Limited focus has been directed toward ethical issues in the primary care office setting. A study was conducted to determine the ethical…
BACKGROUND: The Manchester operation consists of amputation of the cervix, leading some patients to believe that they have undergone a hysterectomy. CASES: A 69-year-old woman with vaginal discharge proved to have a well-differentiated adenocarcinoma…
OBJECTIVE: Our purpose was to study the effect on wound healing when intraperitoneal chemotherapy was instilled on a daily basis. STUDY DESIGN: Intraperitoneal carboplatin, Taxol, or saline solution was instilled daily into 70 rats after they…
BACKGROUND: This study was designed to investigate the frequency of the association between colorectal cancer and peritoneal cytology as well as the impact of surgical resection on conversion of cytology from benign to malignant cells being present.…
This essay begins with a discussion of the primacy of the nuclear family in American drama. Our best playwrights have been strikingly preoccupied with domestic life, consistently portraying the family as a dream of solidarity and a nightmare of…
Spigelian hernias are uncommon, and preoperative diagnosis is often difficult, The use of the laparoscope has simplified the diagnosis and subsequent repair of these rare hernias, We report a case diagnosed and repaired using laparoscopic techniques…
The effects of phenobarbital, phenytoin, and valproic acid on pharmacologically isolated NMDA-EPSP, AMPA-EPSP, and GABA-IPSPs were examined in rat hippocampal slices. Phenobarbital (0.05 mg/ml) had no effect on the NMDA-EPSP, but decreased the slope…
The purpose of this study was to investigate how the aging process alters the basal levels of serotonin, norepinephrine, dopamine, and their respective metabolites in the spinal cord using high-performance liquid chromatography and electrochemical…
The purpose of this study was twofold: 1) to examine photoperiod-dependent and steroid-dependent adjustments in hypothalamic GnRH and catecholamine content in male deer mice, Peromyscus maniculatus, and 2) to evaluate whether the commonly used…
Seventy-three patients with hematological cancers undergoing allogeneic bone marrow transplantation (BMT) were evaluated for event-free survival (EFS) and toxicity, All received 36 g/m(2) cytosine arabinoside (HDA) and 1200 cGy fractionated total…
