Browse Items · NEOMED Bibliography Database

Andrew Jackson's exposure to mercury and lead: poisoned president?

Historians have suggested that US president Andrew Jackson (1767-1845) experienced lead and mercury poisoning following his therapeutic use of calomel (mercurous chloride) and sugar of lead (lead acetate). To evaluate these claims, we performed…

Spondyloarthropathy identified as the etiology of Nubian erosive arthritis.

Slight variation in manifestation of different diseases may allow a single individual with one disease to mimic the "classic" appearance of another, as evidenced by the frequent confusion of spondyloarthropathy with rheumatoid arthritis. Analysis of…

Brainstem neurons with descending projections to the spinal cord of two elasmobranch fishes: thornback guitarfish, Platyrhinoidis triseriata, and horn shark, Heterodontus francisci.

We studied two cartilaginous fishes and described their brainstem supraspinal projections because most nuclei in the reticular formation can be identified that way. A retrogradely transported tracer, horseradish peroxidase or Fluoro-Gold, was…

Inputs to combination-sensitive neurons of the inferior colliculus.

In the mustached bat, combination-sensitive neurons display integrative responses to combinations of acoustic elements in biosonar or social vocalizations. One type of combination-sensitive neuron responds to multiple harmonics of the…

Tags: *Brain Mapping, 1999, Acoustic Stimulation, Animals, Auditory, Brain Stem/*physiology, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Evoked Potentials, Grose C D, Inferior Colliculi/*physiology, Mittmann D H, NEOMED College of Medicine, Neurons/*physiology, The Journal of comparative neurology, Wenstrup J J

Castration differentially alters [3H]nisoxetine binding to norepinephrine uptake sites in olfactory bulb and frontal cortex of male rats.

In the present study, [3H]nisoxetine binding to norepinephrine (NE) uptake sites and [3H]norepinephrine uptake were investigated within olfactory bulb (OB) and frontal cortex homogenates from intact and castrated male rats. Statistically significant…

Tags: *Orchiectomy, 1999, Adrenergic/drug effects/*metabolism, Animals, Boja J W, Dluzen D E, Fluoxetine/*analogs & derivatives/metabolism, Frontal Lobe/drug effects/*metabolism, Kinetics, Male, Norepinephrine/metabolism, Olfactory Bulb/drug effects/*metabolism, Rats, Receptors, Shang Y, Sprague-Dawley, Synapse (New York, N.Y.), Synaptosomes/drug effects/metabolism, Testosterone/pharmacology

Alterations in nigrostriatal dopaminergic function within BDNF mutant mice.

The influence of brain-derived neurotrophic factor (BDNF) upon the nigrostriatal dopaminergic system was evaluated in weanling and adult mice carrying a targeted inactivated BDNF gene. Regional specificity of this BDNF mutation was assessed by…

Use of brain slices to study long-term potentiation and depression as examples of synaptic plasticity.

Brain slices have been responsible for the majority of advances in our understanding of the cellular aspects of altered synaptic strength underlying memory, long-term potentiation (LTP) and long-term depression (LTD), and increases and decreases,…

Tags: *Long-Term Potentiation, *Neuronal Plasticity, 1999, Animals, Brain/*physiology, Electrophysiology/methods, Glutamic Acid/physiology, In Vitro Techniques, Memory/*physiology, Methods (San Diego, Calif.), Models, Neurological, Synapses/*physiology, Synaptic Transmission, Teyler T J

Vagal afferents from the uterus and cervix provide direct connections to the brainstem.

Previous anatomical studies demonstrated vagal innervation to the ovary and distal colon and suggested the vagus nerve has uterine inputs. Recent behavioral and physiological evidence indicated that the vagus nerves conduct sensory information from…

Tags: 1999, Animals, Berthoud H R, Brain Stem/*anatomy & histology, Cell and tissue research, Cervix Uteri/*innervation, Collins J J, Estrogen/metabolism, Female, Immunohistochemistry, Lin C E, Neurons/cytology/metabolism, Papka R E, Rats, Receptors, Sprague-Dawley, Uterus/*innervation, Vagus Nerve/*anatomy & histology/metabolism

Cholinergic neurons of the pelvic autonomic ganglia and uterus of the female rat: distribution of axons and presence of muscarinic receptors.

Acetylcholine (ACh) stimulates contraction of the uterus and dilates the uterine arterial supply. Uterine cholinergic nerves arise from the paracervical ganglia and were, in the past, characterized based on acetylcholinesterase (AChE) histochemistry.…

Calretinin-immunoreactive nerves in the uterus, pelvic autonomic ganglia, lumbosacral dorsal root ganglia and lumbosacral spinal cord.

Nerves containing the calcium-binding protein calretinin have been reported in several organs but not in female reproductive organs and associated ganglia. This study was undertaken to determine if nerves associated with the uterus contain calretinin…

Legionella.

Since the identification of Legionella two decades ago, a vast amount of information has accumulated concerning the microbiology, clinical manifestations, and therapy of infections due to these organisms. There are now more than 40 species of…

Tags: 1999, Current infectious disease reports, Department of Internal Medicine, File, NEOMED College of Medicine, Plouffe

Awake aortic aneurysm repair in patients with severe pulmonary disease.

BACKGROUND: We report the use of retroperitoneal aortic aneurysm repair utilizing exclusive regional anesthesia (no intubation or inhalation anesthetic) in high pulmonary risk patients. METHODS: Six patients were retrospectively reviewed. Pulmonary…

Tags: *Consciousness, 1999, Abdominal/*surgery, Administration, Aged, Albuterol/administration & dosage/therapeutic use, American journal of surgery, Anesthesia, Aortic Aneurysm, Blood Loss, Bronchodilator Agents/administration & dosage/therapeutic use, Critical Care, Epidural, Forced Expiratory Volume/physiology, General, Hirko M K, Home Care Services, Hospitalization, Humans, Hypnotics and Sedatives/administration & dosage, Iliac Aneurysm/*surgery, Inhalation, Intravenous, Koler A J, Labat G C, Length of Stay, Lung Diseases/*complications/drug therapy/therapy, McGregor W E, Oxygen Inhalation Therapy, Perni V, Retroperitoneal Space, Retrospective Studies, Risk Factors, Rubin J R, Safety, Steroids/administration & dosage/therapeutic use, Surgical, Theophylline/administration & dosage/therapeutic use, Time Factors, Vital Capacity/physiology

Aging and neuropathic pain.

Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was…

Use of in vitro superfusion to assess the dynamics of striatal dopamine clearance: influence of estrogen.

To determine the feasibility of assessing dopamine uptake using in vitro superfusion, striatal tissue from ovariectomized female rats was infused with dopamine (1 microM), nomifensine (1 mM), or a combination of dopamine and nomifensine. Treatment…

Tags: 1999, Animals, Brain research, Corpus Striatum/drug effects/*physiology, Disshon K A, Dluzen D E, Dopamine/*metabolism/pharmacology, Estradiol/*pharmacology, Female, Kinetics, Nomifensine/*pharmacology, Ovariectomy, Rats, Sprague-Dawley

Constant set points for pH and P(CO2) in cold-submerged skin-breathing frogs.

The low temperatures encountered by overwintering frogs result in a large downregulation of metabolism and behaviour. However, little is known about acid-base regulation in the extreme cold, especially when frogs become exclusive skin-breathers…

Tags: *Hydrogen-Ion Concentration, *Skin Physiological Phenomena, 1999, Acclimatization, Animals, Boutilier R G, Carbon Dioxide/blood/*metabolism, Cold Temperature, Immersion, Muscle, Oxygen/*metabolism, Partial Pressure, Rana temporaria/*physiology, Respiration physiology, Seasons, Skeletal/physiology, Tattersall G J

Chordee: varied opinions and treatments as documented in a survey of the American Academy of Pediatrics, Section of Urology.

OBJECTIVES: Consensus has not been established as to the best treatment of congenital chordee. Outcomes analysis of treatment options are limited by the prevailing use of ambiguous terminology. We sought to clarify the frequently used term…

Tags: 1999, Bologna R A, Child, Data Collection, Humans, Male, Male/*methods, McMahon D R, Medical, Nasrallah P F, Noah T A, Pediatrics, Penis/*abnormalities/*surgery, Societies, Urologic Surgical Procedures, Urology

Why adult mammalian intrafusal and extrafusal fibers contain different myosin heavy-chain isoforms.

Multiple isoforms of the contractile protein myosin are present in mammalian skeletal muscles. The diversity of the heavy-chain subunits of myosin (MyHCs) in intrafusal fibers is thought to reflect a pathway of differentiation that is unique to…

Resveratrol inhibition of herpes simplex virus replication.

Resveratrol, a phytoalexin, was found to inhibit herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) replication in a dose-dependent, reversible manner. The observed reduction in virus yield was not caused by the direct inactivation of HSV by…

The effect of rubrospinal tractotomy on a conditioned limb response in the cat.

Five cats were trained to perform a forelimb conditioned response to a paired tone CS/shock UCS. Rubrospinal tract section ipsilateral to the trained limb was carried out following criterion CR performance. Lesion sites were identified histologically…

Tags: 1999, Animal/physiology, Animals, Behavior, Behavioural brain research, Cats, Conditioning, Forelimb/innervation/*physiology, Functional Laterality/physiology, Neural Pathways/anatomy & histology/physiology, Operant/*physiology, Red Nucleus/anatomy & histology/*physiology, Spinal Cord/anatomy & histology/*physiology, Stereotaxic Techniques, Voneida T J

Immunization with a LEAPS heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1.

A ligand epitope antigen presentation system (LEAPS) heteroconjugate vaccine containing a CTL epitope (H1) from the HSV-1 immediate early protein ICP27 (322-332) and a peptide sequence (J) from beta-2-microglobulin (35-50) elicited protection from…

Chronic lymphocytic leukemia-associated membranous glomerulopathy: remission with fludarabine.

In some individuals, chronic lymphocytic leukemia (CLL) may be associated with glomerular disease from membranous nephropathy with resultant nephrotic syndrome. CLL is characterized by abnormal immunoregulation with a malignant clonal proliferation…

Evaluation of the patient with seizures: an evidence based approach.

Statistics tell us that as many as 1 in 20 members of the population will suffer a seizure at some point in their lifetime, a figure which becomes even more likely if one lives to the age of 80. Thus, a careful evidence based approach to the patient…

Anti-tobacco socialization in homes of African-American and white parents, and smoking and nonsmoking parents.

PURPOSE: To examine parental perceptions and behaviors with regard to teen smoking, comparing African-American and white parents, and those who did and did not smoke. METHODS: Focus groups consisting of African-American and white parents who smoked…

Remission of nephrotic syndrome in type 1 diabetes: long-term follow-up of patients in the Captopril Study.

In 1994, we reported a 3.4 +/- 0.8 year follow-up of the eight patients who experienced remission of nephrotic syndrome during the Collaborative Study Group-sponsored, multicenter trial of captopril therapy in patients with type 1 diabetes with…

Tags: 1999, Adult, American journal of kidney diseases : the official journal of the National Kidney Foundation, Angiotensin-Converting Enzyme Inhibitors/*therapeutic use, Antihypertensive Agents/*therapeutic use, Bain R P, Blood Pressure/drug effects, Blumenthal S, Captopril/*therapeutic use, Cattran D, Chronic/etiology, Creatinine/blood, Department of Internal Medicine, Diabetes Mellitus, Diabetic Nephropathies/*drug therapy/physiopathology, Disease Progression, Female, Follow-Up Studies, Hebert L A, Humans, Kidney Failure, Levey A S, Lewis E J, Lewis J B, Male, Middle Aged, NEOMED College of Medicine, Nephrotic Syndrome/complications/*drug therapy/physiopathology, Prospective Studies, Proteinuria, Randomized Controlled Trials as Topic, Remission Induction, Rohde R D, Spitalewitz S, Type 1/*complications, Whittier F, Wilmer W A

Diagnosis and treatment of diabetic foot infections.

Prompt clinical diagnosis and timely treatment are the hallmarks of the proper care of diabetic patients with foot infections. The importance of careful clinical foot examination cannot be overemphasized. When infection is suspected, effort should be…

Tags: 1999, Anti-Bacterial Agents/*therapeutic use, Bacterial Infections/*diagnostic imaging/*drug therapy, Bailliere's best practice & research. Clinical rheumatology, Department of Internal Medicine, Diabetic Foot/*microbiology, File T M Jr, Humans, NEOMED College of Medicine, Radiography, Tan J S

Determination of laboratory specific percent normal sperm morphology value based on prevasectomy ("fertile") ejaculates.

Semen assessments were performed on ejaculates from 25 men with proven fertility requesting vasectomy. Multiple cytological slides were made simultaneously from each ejaculate and analyzed by a single technician. The morphology data obtained were…

Tags: 1999, Archives of andrology, Babbo C J, Ejaculation, Fertility, Hecht B R, Humans, Jeyendran R S, Male, Reference Values, Reproducibility of Results, Sperm Count, Sperm Motility, Spermatozoa/classification/*cytology, Vasectomy

Antiviral activity of magnesium and magnesium/poly r(A-U) combinations against two RNA viruses.

Magnesium (Mg2+) potentiated the anti-vesicular stomatitis virus (VSV) activity of poly r(A-U) or poly r(G-C) and the anti-HIV-1 activity of poly r(A-U). Mg2+ did not affect the anti-VSV activity of poly (rI).poly (rC), poly (dA-dT).poly (dA-dT) or…

Tags: 1999, Antiviral Agents/*pharmacology, Gilloteaux J, HIV-1/*drug effects, Humans, Jamison J, Magnesium/*pharmacology, Microbial Sensitivity Tests, Nassiri M R, Nucleosides & nucleotides, Poly A-U/*pharmacology, Summers J, Tsai C C, Vesicular stomatitis Indiana virus/*drug effects

Ankle morphology of the earliest Cetaceans and its implications for the phylogenetic relations among ungulates.

Recent molecular studies are inconsistent with ungulate phylogenetic trees that are based on morphological traits. These inconsistencies especially relate to the position of cetaceans and perissodactyls. Evaluation of the close phylogenetic ties…

Tags: *Phylogeny, 1999, Animals, Cetacea/*anatomy & histology/classification, Department of Anatomy & Neurobiology, Hindlimb/anatomy & histology, Joints/*anatomy & histology, Madar S I, NEOMED College of Medicine, Ruminants/*anatomy & histology/classification, Systematic biology, Thewissen J G

Clinical characteristics of Chlamydia pneumoniae infection as the sole cause of community-acquired pneumonia.

The clinical characteristics of 26 patients with community-acquired pneumonia due to Chlamydia pneumoniae as the only identified pathogen who required hospitalization were evaluated. Most patients (18) had reinfection based on serological results.…

The other causes of 'atypical' pneumonia.

Mycoplasma, Chlamydia and Legionella are the usual organisms considered to be the etiologic agents of 'atypical' pneumonia. Other microorganisms such as bacteria, viruses, parasites, fungi and mycobacteria can also present with atypical pneumonia…

Tags: 1999, Current opinion in infectious diseases, Tan J S

Uninstrumented posterolateral lumbar fusion for single level isolated disc resorption and/or degenerative disc disease.

The limited soft-tissue envelope technique for an uninstrumented single-level posterolateral lumbar fusion has been studied in a group of 23 patients. It resulted in a solid fusion in 21 of 23 (91%) patients. Overall, 18 of 23 (78%) patients had a…

Tags: 1999, Adult, Aged, Bone Resorption/diagnosis/*surgery, Female, Humans, Intervertebral Disc/diagnostic imaging/pathology/*surgery, Journal of spinal disorders, Lumbar Vertebrae/diagnostic imaging/pathology/*surgery, Magnetic Resonance Imaging, Male, McCulloch J A, Medical Illustration, Middle Aged, Radiography, Retrospective Studies, Spinal Diseases/diagnosis/*surgery, Spinal Fusion/*methods, Treatment Outcome

Seminoma mimicking epididymo-orchitis on scrotal scintigraphy

Tags: 1999, Clinical nuclear medicine, Goyal, Hanelin

Melanotic schwannoma. An unusual case of an ossified soft tissue mass.

A case of a melanotic schwannoma presenting as a soft tissue mass of the abductors of the hip is reported. The radiographic findings suggested myositis ossificans, but several subtle findings raised the concern for something else. A bilobed…

Painless deformity of a long finger phalanx of a 4-year-old girl.

Spinous process osteotomies to facilitate lumbar decompressive surgery.

STUDY DESIGN: A technique for lumbar decompression using spinous process osteotomies is described, and the outcomes are studied prospectively. OBJECTIVE: To describe a technique that affords a wide exposure for decompression while minimizing damage…

Discoid lateral meniscus.

Tags: 1999, Child, Eilert R E, Fleissner P R, Humans, Magnetic Resonance Imaging, Menisci, Radiography, The American journal of knee surgery, Tibial/*abnormalities/anatomy & histology/diagnostic imaging/surgery, Treatment Outcome

Equatorius: a new hominoid genus from the Middle Miocene of Kenya.

A partial hominoid skeleton just older than 15 million years from sediments in the Tugen Hills of north central Kenya mandates a revision of the hominoid genus Kenyapithecus, a possible early member of the great ape-human clade. The Tugen Hills…

Effect of epinephrine on alveolar liquid clearance in the rat.

Endogenous epinephrine has been found to increase alveolar liquid clearance (ALC) in several pulmonary edema models. In this study, we infused epinephrine intravenously for 1 h in anesthetized rats to produce plasma epinephrine concentrations…

VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo.

N-methyl-D-aspartate receptor/channel (NMDAR) and voltage-dependent calcium channel (VDCC) antagonists applied independently reduce the magnitude of long-term potentiation (LTP) in area CA1 of the hippocampal slice preparation. When used in…

Tags: 1999, Animals, Calcium Channel Blockers/*pharmacology, Dizocilpine Maleate/pharmacology, Excitatory Amino Acid Antagonists/*pharmacology, Excitatory Postsynaptic Potentials/drug effects, Hippocampus/*drug effects, Journal of neurophysiology, Long-Evans, Long-Term Potentiation/*drug effects, Male, Membrane Potentials/physiology, Morgan S L, N-Methyl-D-Aspartate/*antagonists & inhibitors, Rats, Receptors, Teyler T J, Verapamil/pharmacology

Delay-tuned neurons in the inferior colliculus of the mustached bat: implications for analyses of target distance.

We examined response properties of delay-tuned neurons in the central nucleus of the inferior colliculus (ICC) of the mustached bat. In the mustached bat, delay-tuned neurons respond best to the combination of the first-harmonic, frequency-modulated…

Tags: 1999, Animal/physiology, Animals, Chiroptera/*physiology, College of Anatomy & Neurobiology, Department of Anatomy & Neurobiology, Echolocation/*physiology, Inferior Colliculi/cytology/*physiology, Journal of neurophysiology, NEOMED College of Medicine, Neural Inhibition/physiology, Neurons/*physiology, Portfors C V, Reaction Time/physiology, Vocalization, Wenstrup J J

Browse Items (176 total)