Browse Items · NEOMED Bibliography Database

Effect of a standardized pharyngitis treatment protocol on use of antibiotics in a pediatric emergency department.

BACKGROUND: Pharyngitis is a common complaint in pediatric patients. If clinical parameters are used alone, bacterial pathogens will be wrongly implicated in many cases. A nonstandardized approach to the treatment of children with pharyngitis in an…

New technique for studying reaction forces during primate behaviors on vertical substrates.

Recording reaction forces from primates during behaviors on vertical substrates, such as leaping, climbing, or biting trees, typically requires the design and construction of customized recording devices or mounting commercially available force…

Tags: 2004, American journal of physical anthropology, Animals, Biomechanical Phenomena, Biophysics/instrumentation, Ergometry/*instrumentation/*methods, Motor Activity/*physiology, Primates/*physiology, Schmitt Daniel, Vinyard Christopher J

Age-related expression patterns of Bag-1 and Bcl-2 in growth plate and articular chondrocytes.

Aging cartilage displays increased chondrocyte apoptosis and decreased responsiveness of chondrocytes to growth factors. The molecular mechanisms responsible for these changes have not been identified. Bag-1 is a Bcl-2-binding protein that promotes…

Growth hormone therapy for short stature in Diamond Blackfan anemia.

BACKGROUND: We report a 13-year-old male with Diamond Blackfan anemia and short stature. He had a normal biochemical response to growth hormone (GH) stimulation, but his bone age was delayed, his insulin-like growth factor 1 (IGF-1) was low, and he…

Tags: 2004, Adolescent, Anemia, Body Height, Diamond-Blackfan/*complications, Growth Disorders/*drug therapy/*etiology, Haider Anzar, Hord Jeffrey, Human Growth Hormone/pharmacology/*therapeutic use, Humans, Male, Pediatric blood & cancer, Scott Emily Gale, Treatment Outcome

Ileal pouch perforation in pregnancy: report of a case and review of the literature.

Acute abdominal pain, especially in the presence of free intra-abdominal air, in a pregnant patient who has previously undergone ileal pouch-anal anastomosis may be a result of acute perforation of the pouch. The case of a 30-year-old multigravida…

Recent advances in clinical use of opioids.

Opioid therapy for pain is the subject of numerous randomized clinical trials. Opioids are being developed for delivery by a wide variety of mechanisms. New opioids are becoming available for clinical use. This review surveys recent developments in…

Tags: 2004, Analgesics, Chevlen Eric, Clinical Trials as Topic, Current pain and headache reports, Department of Internal Medicine, Humans, NEOMED College of Medicine, Opioid/administration & dosage/pharmacology/*therapeutic use, Pain/*drug therapy

Stimulation of distal airspace fluid clearance in guinea pigs involves bumetanide-sensitive ion transport.

OBJECTIVE: This study was undertaken to test the hypothesis that beta-adrenoceptor stimulation of fetal lung fluid absorption in near-term guinea pig fetuses involves bumetanide-sensitive ion transport. STUDY DESIGN: Fetuses were obtained from…

Resident physician attire: does it make a difference to our patients?

OBJECTIVES: This study was performed to examine the preferences of patients regarding physician attire, and if their perception of physician competence was influenced by the physicians' clothing style. METHODS: Patients attending the obstetrics and…

Does preoperative rofecoxib (Vioxx) decrease postoperative pain with laparoscopic cholecystectomy?

BACKGROUND: A prospective, randomized, double-blinded clinical trial was designed to study the effects of preemptive rofecoxib (Vioxx) analgesia in patients undergoing elective laparoscopic cholecystectomy. METHODS: One hundred-twenty patients were…

Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice.

Resveratrol (3,5,4'-trihydroxystilbene) is a natural component of certain foods, such as grapes, that has been shown to have anti-herpes simplex virus (HSV) activity in vitro. To determine if it is active in vivo, the abraded epidermis of SKH1 mice…

Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein.

Oxysterol 7alpha-hydroxylase (CYP7B1) metabolizes oxysterols, potent regulators of lipid homeostasis. Very little is known about transcriptional regulation of human CYP7B1. The present results indicate that sterol response element binding protein…

Cell cycle arrest and autoschizis in a human bladder carcinoma cell line following Vitamin C and Vitamin K3 treatment.

Exponentially growing cultures of human bladder tumor cells (T24) were treated with Vitamin C (VC) alone, Vitamin K(3) (VK(3)) alone, or with a VC:VK(3) combination for 1, 2, or 4hr. Flow cytometry of T24 cells exposed to the vitamins for 1h revealed…

Tamoxifen increases methamphetamine-evoked dopamine output from superfused striatal tissue fragments of male mice.

The antiestrogen, tamoxifen (TMX), has been shown to function as a neuroprotectant against the nigrostriatal dopaminergic (NSDA) neurotoxin, methamphetamine (MA), within male mice. In the present report, we examined the effects of a combined infusion…

Tags: 2004, Animals, Brain research, Corpus Striatum/*drug effects/*metabolism, Dluzen Dean E, Dopamine Agents/*pharmacology, Dopamine Plasma Membrane Transport Proteins, Dopamine/*metabolism, Drug Synergism, Estrogen Antagonists/*pharmacology, Inbred Strains, Male, Membrane Glycoproteins/metabolism, Membrane Transport Proteins/metabolism, Methamphetamine/*pharmacology, Mice, Nerve Tissue Proteins/metabolism, Tamoxifen/*pharmacology, Willett Matthew C

Pregnancy zone protein is a carrier and modulator of placental protein-14 in

A successful pregnancy can only occur when the maternal immune system fails to attack the allogeneic fetus. Two plasma proteins with described immunoregulatory activities, pregnancy zone protein (PZP) and placental protein-14 (PP14; also known as…

Evolution of amoxicillin/clavulanate in the treatment of adults with acute bacterial rhinosinusitis and community-acquired pneumonia in response to antimicrobial-resistance patterns.

Current treatment guidelines for community-acquired respiratory tract infections no longer depend solely on the characteristics of the patient and the clinical syndrome, but on those of the offending pathogen, including presence and level of…

Tags: 2004, Amoxicillin-Potassium Clavulanate Combination/*therapeutic use, Anti-Bacterial Agents/pharmacology, Bacteria/drug effects/isolation & purification, Bacterial, Benninger Michael S, Clinics in laboratory medicine, Combination/*therapeutic use, Community-Acquired Infections/drug therapy/microbiology, Department of Internal Medicine, Drug Resistance, Drug Therapy, File Thomas M Jr, Humans, Jacobs Michael R, Microbial Sensitivity Tests, NEOMED College of Medicine, Pneumonia/*drug therapy/microbiology, Sinusitis/*drug therapy/microbiology

Nonresponses and treatment failures with conventional empiric regimens in patients with community-acquired pneumonia.

Although most patients with suspected CAP respond to empiric therapy,a small number of patients do not respond in the expected fashion. Age and underlying comorbid conditions have a strong influence on the course of illness. Less common causes of…

Tags: 2004, Anti-Bacterial Agents/therapeutic use, Bacterial, Community-Acquired Infections/drug therapy/mortality, Diagnostic Errors, Drug Resistance, Humans, Infectious disease clinics of North America, Pneumonia/diagnosis/*drug therapy/mortality, Risk Factors, Tan James S, Treatment Failure

Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.

Tags: 2004, Animals, Bile Acids and Salts/*biosynthesis, Chiang John Y L, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, Feedback, Humans, Journal of hepatology, Lipid Metabolism, NEOMED College of Medicine, Physiological, Receptors

Effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat.

The effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat were investigated. A plantar analgesic meter was used to measure carrageenan-induced changes in paw withdrawal latency (PWL) values, and von…

The effect of gender and the neurotrophin, BDNF, upon methamphetamine-induced neurotoxicity of the nigrostriatal dopaminergic system in mice.

The interactive effects between gender and a selective alteration in the neurotrophin, brain-derived neurotrophic factor (BDNF) upon methamphetamine (MA)-induced neurotoxicity of the nigrostriatal dopaminergic (NSDA) system were assessed. MA…

Age-related changes in nigrostriatal dopaminergic function are accentuated in +/- brain-derived neurotrophic factor mice.

The effects of a deletion for the brain derived neurotrophic factor (BDNF) allele (+/- BDNF) upon age-related changes in nigrostriatal dopaminergic (NSDA) function were assessed. Behavioral (beam crossing and spontaneous activity) and neurochemical…

Tags: *Aging, 2004, Anderson L I, Animals, Brain-Derived Neurotrophic Factor/*genetics/*metabolism, Corpus Striatum/*metabolism, Dluzen D E, Dopamine/*biosynthesis, Joyce J N, Kucera J, McDermott J L, Mice, Motor Activity/physiology, Mutant Strains, Mutation, Neuroscience, Osredkar T, Substantia Nigra/*metabolism, Walro J M

Vestibular-evoked myogenic potentials in three patients with large vestibular aqueduct.

An enlarged vestibular aqueduct (LVA) is a common congenital inner ear anomaly responsible for some unusual vestibular and audiological symptoms. Most of the cases show bilateral early onset and progressive hearing loss in children. The gross…

Selected principles of perinatal-neonatal glucose metabolism.

While the fetus is completely dependent on his/her mother for glucose and other nutrient transfer across the placenta, the adult is completely independent, especially one who is neither pregnant nor diabetic. The neonate is considered to be in a…

Tags: 2004, Blood Glucose/metabolism, Cowett Richard M, Farrag Hussien M, Female, Fetus/*metabolism, Glucose/*metabolism, Humans, Hyperglycemia/embryology/physiopathology, Hypoglycemia/embryology/physiopathology, Infant, Liver/*embryology/*metabolism, Newborn/*metabolism, Pregnancy, Seminars in neonatology : SN

Eocene evolution of whale hearing.

The origin of whales (order Cetacea) is one of the best-documented examples of macroevolutionary change in vertebrates. As the earliest whales became obligately marine, all of their organ systems adapted to the new environment. The fossil record…

Clinical efficacy of newer agents in short-duration therapy for community-acquired pneumonia.

Streptococcus pneumoniae, the most important respiratory tract pathogen implicated in community-acquired pneumonia (CAP), is becoming increasingly resistant in vitro to the beta -lactams and macrolides, and fluoroquinolone resistance has been…

Tags: 2004, Anti-Infective Agents/*therapeutic use, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/*drug therapy/microbiology, Department of Internal Medicine, File Thomas M Jr, Humans, NEOMED College of Medicine, Pneumonia/*drug therapy/microbiology, Streptococcus pneumoniae/drug effects/isolation & purification, Treatment Outcome

Attitudes of female nurses and female residents toward each other: a qualitative study in one U.S. teaching hospital.

PURPOSE: To describe the attitudes of female nurses and female resident physicians toward each other in surgery, internal medicine, obstetrics-gynecology, and emergency medicine in one Midwest teaching hospital in the United States. METHOD: Using a…

Handheld computer use in a family medicine clerkship.

PURPOSE: The objectives of this study were to track students' use of medical and nonmedical personal digital assistant (PDA) software and to obtain students' ratings of the usefulness of PDAs in a family medicine clerkship. METHOD: During the…

US emergency department visits for hip fracture, 1992-2000.

BACKGROUND: Hip fracture is a significant injury for older persons. Little has been reported about emergency department (ED) care of these patients. OBJECTIVE: To characterize the management of older patients treated in the ED for hip fracture with…

Tags: 2004, 80 and over, Age Factors, Aged, Analgesia/statistics & numerical data, Camargo Carlos A Jr, Emergency Medical Services/*statistics & numerical data, Emond Jennifer A, European journal of emergency medicine : official journal of the European Society for Emergency Medicine, Female, Gerson Lowell W, Hip Fractures/diagnosis/*epidemiology/therapy, Humans, Male, Middle Aged, Sex Factors, United States/epidemiology

Entero mesh vaginal fistula secondary to abdominal sacral colpopexy.

BACKGROUND: Abdominal sacral colpopexy is a popular method for resupporting the vaginal apex. Bleeding and infection are the most common complications. We report a complication resulting in a small bowel fistula. CASE: A 48-year-old woman developed a…

Tags: *Surgical Mesh, 2004, Abdomen, Female, Gynecologic Surgical Procedures, Hopkins Michael P, Humans, Intestinal Fistula/*etiology, Intestine, Middle Aged, Obstetrics and gynecology, Postoperative Complications/*etiology, Rooney Christopher, Sacrum, Small, Uterine Prolapse/surgery, Vaginal Fistula/*etiology

Spermatic cord torsion with preserved testis perfusion: initial anatomical observations.

PURPOSE: Despite the high sensitivity and specificity of scrotal ultrasonography, there continue to be reports of missed torsion. These "false-negative" scans are attributed to technical factors and intermittent torsions. We hypothesize that patients…

Tags: *Ultrasonography, 2004, Adolescent, Bentley Dennis F, Child, Doppler, Humans, Male, McMahon Daniel R, Nasrallah Phillip F, Regional Blood Flow, Retrospective Studies, Ricchiuti Daniel J, Spermatic Cord Torsion/*diagnostic imaging, Spermatic Cord/anatomy & histology/diagnostic imaging, Testis/*blood supply, The Journal of urology

A comparison of the National Ambulatory Medical Care Survey (NAMCS) measurement approach with direct observation of outpatient visits.

BACKGROUND: The National Ambulatory Medical Care Survey (NAMCS) informs a wide range of important policy and clinical decisions by providing nationally representative data about outpatient practice. However, the validity of the NAMCS methods has not…

The educational experience of pediatric emergency medicine fellows in the use and application of procedural sedation/analgesia.

OBJECTIVES: The purpose of this study is to describe the clinical and educational experience provided to the pediatric emergency medicine (PEM) fellows in procedural sedation/analgesia during their course of training. METHODS: A nonanonymous survey…

Gynecomastia: an outcome analysis.

BACKGROUND: Gynecomastia refers to the presence of femalelike mammary glands in a male. This disorder can lead to significant psychologic stress and self-consciousness. This study consists of a chart review of 174 patients treated surgically between…

Tags: 2004, Adolescent, Adult, Aged, Annals of plastic surgery, Child, Gynecomastia/*surgery, Humans, Lehman James A Jr, Male, Middle Aged, Parker Michael G, Pedersen John C, Retrospective Studies, Tantri M Devi Prasad, Treatment Outcome, Wagner Douglas S, Wiesman Irvin M

Ischemic colitis revisited: a prospective study identifying hypercoagulability as a risk factor.

BACKGROUND: Although causes for ischemic colitis have been identified, many cases are deemed idiopathic. Some reports suggest an association between ischemic colitis and coagulation disorders. Our purpose was to explore the relationship of ischemic…

Effectiveness of screening and treatment for depression in ambulatory indigent patients.

OBJECTIVE: To determine the effectiveness of screening and treatment for depression among ambulatory indigent patients visiting resident physicians. DESIGN: Two-group randomized trial (N = 33 intervention, N = 28 usual care) with baseline, 6-month,…

Simulation of breast cancer screening: quality assessment of two protocols.

Healthcare professionals must make breast cancer screening decisions without the help of clear answers in current medical knowledge. This study used computer simulation to evaluate two screening protocols. The American Cancer Society (ACS) protocol…

Recreational injuries among older Americans, 2001.

OBJECTIVE: To describe the epidemiology of non-fatal recreational injuries among older adults treated in United States emergency departments including national estimates of the number of injuries, types of recreational activities, and diagnoses.…

Tags: *Recreation, 2004, 80 and over, Age Distribution, Aged, Athletic Injuries/epidemiology, Bone/epidemiology, Emergencies, Exercise, Female, Fractures, Gerson L W, Humans, Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention, Male, Sex Distribution, Stevens J A, United States/epidemiology, Wounds and Injuries/*epidemiology

IL-1beta stimulates alveolar fluid absorption in fetal guinea pig lungs via the hypothalamus-pituitary-adrenal gland axis.

We tested the hypothesis that interleukin (IL)-1beta-induced cortisol synthesis stimulates alveolar fluid clearance in preterm fetuses. IL-1beta was administered subcutaneously daily to timed-pregnant guinea pigs for 3 days with and without…

Dose-response effects of estrogen and tamoxifen upon methamphetamine-induced behavioral responses and neurotoxicity of the nigrostriatal dopaminergic system in female mice.

In the present experiment we evaluated the dose-response effects of estrogen (estradiol benzoate; EB) and tamoxifen (TMX) in modulating the acute behavioral and chronic effects of methamphetamine (MA) upon the nigrostriatal dopaminergic (NSDA) system…

Factors affecting missed appointment rates for pediatric patients insured by medicaid in a traditional hospital-based resident clinic and hospital-owned practice settings.

Missed appointment rates (MAR) of pediatric patients insured by Medicaid and seen in a traditional hospital-based continuity (teaching) clinic were compared to the rates for the same patients after their care had been transitioned to a community…

Tags: *Appointments and Schedules, *Medicaid, *Pediatrics, 2004, Chi-Square Distribution, Clinical pediatrics, Continuity of Patient Care, Dormo Cynthia A, Hospitals, Humans, Office Visits/*statistics & numerical data, Pediatric/*statistics & numerical data, Powell Keith R, Specht Elizabeth M, United States

The role of sensory neurons in cervical ripening: effects of estrogen and neuropeptides.

Central nervous system nuclei and circuits, such as the medial preoptic, ventromedial and paraventricular nuclei of the hypothalamus, play important roles in reproduction and parturition, and are influenced by estrogen. Peripheral autonomic and…

Tags: 2004, Afferent/metabolism/*physiology, Cervical Ripening/*physiology, Cervix Uteri/innervation, Estrogen/physiology, Estrogens/*physiology, Female, Ganglia, Humans, Mowa C N, Neurons, Neuropeptides/biosynthesis/*physiology, Papka R E, Pregnancy, Receptors, Spinal/physiology, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

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