Browse Items · NEOMED Bibliography Database

Type VI collagen induces cardiac myofibroblast differentiation: implications for postinfarction remodeling.

Cardiac fibroblast (CF) proliferation and differentiation into hypersecretory myofibroblasts can lead to excessive extracellular matrix (ECM) production and cardiac fibrosis. In turn, the ECM produced can potentially activate CFs via distinct…

Impaired alveolar liquid clearance after 48-h isoproterenol infusion spontaneously recovers by 96 h of continuous infusion.

We previously demonstrated that 48-h isoproterenol (Iso) infusion in rats impaired the ability of beta-adrenoceptor (beta-AR) agonists to increase alveolar liquid clearance (ALC). In this study, we determined whether this impairment persisted over…

Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses.

We hypothesized that congenital diaphragmatic hernia (CDH) may decrease distal air space fluid absorption due to immaturity of alveolar epithelial cells from a loss of the normal epithelial Na+ transport, as assessed by amiloride and epithelial Na+…

RNA interference for alpha-ENaC inhibits rat lung fluid absorption in vivo.

We used siRNA against the alpha-ENaC (epithelial Na channel) subunit to investigate ENaC involvement in lung fluid absorption in rats by the impermeable tracer technique during baseline and after beta-adrenoceptor stimulation by terbutaline.…

Auditory responses in the cochlear nucleus of awake mustached bats: precursors to spectral integration in the auditory midbrain.

In the cochlear nucleus (CN) of awake mustached bats, single- and two-tone stimuli were used to examine how responses in major CN subdivisions contribute to spectrotemporal integrative features in the inferior colliculus (IC). Across CN subdivisions,…

Roles of inhibition in complex auditory responses in the inferior colliculus: inhibited combination-sensitive neurons.

We studied the functional properties and underlying neural mechanisms associated with inhibitory combination-sensitive neurons in the mustached bat's inferior colliculus (IC). In these neurons, the excitatory response to best frequency tones was…

Effects of estrogen and related agents upon methamphetamine-induced neurotoxicity within an impaired nigrostriatal dopaminergic system of ovariectomized mice.

Estrogen increases methamphetamine (MA)-induced neurotoxicity within the impaired nigrostriatal dopaminergic (NSDA) system of ovariectomized female mice, as defined by enhanced striatal dopamine (DA) depletion. In this study we compared the effects…

Alveolar epithelial ion and fluid transport: recent progress.

Tags: 2006, American journal of respiratory cell and molecular biology, Animals, Biological Transport, Body Fluids/*metabolism, Epithelium/*metabolism, Folkesson Hans G, Humans, Lung/cytology/*metabolism/pathology, Matthay Michael A, Pulmonary Alveoli/*cytology, Sodium Channels/metabolism

Use of the Sequential Intercept Model as an approach to decriminalization of people with serious mental illness.

The Sequential Intercept Model provides a conceptual framework for communities to use when considering the interface between the criminal justice and mental health systems as they address concerns about criminalization of people with mental illness.…

Tags: *Mental Disorders, *Models, 2006, Cooperative Behavior, Criminal Law/*organization & administration, Department of Psychiatry, Emergency Services, Griffin Patricia A, Humans, Munetz Mark R, NEOMED College of Medicine, Ohio, Organizational, Psychiatric services (Washington, D.C.), Psychiatric/*organization & administration

Police use of the taser with people with mental illness in crisis.

Tags: *Conflict (Psychology), *Crisis Intervention, *Police, 2006, Crime/*statistics & numerical data, Department of Psychiatry, Electroshock/*instrumentation, Firearms, Fitzgerald Antonia, Humans, Law Enforcement, Mental Disorders/*epidemiology/*psychology, Munetz Mark R, NEOMED College of Medicine, Psychiatric services (Washington, D.C.), United States, Woody Michael

Ethyl vinyl chloride vapocoolant spray fails to decrease pain associated with intravenous cannulation in children.

The purpose of the study was to determine the effect of ethyl vinyl chloride vapocoolant spray on pain reported by children undergoing intravenous cannulation. A randomized, double-blinded, placebo-controlled trial was conducted on eligible children…

Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins.

BACKGROUND: Metabotropic glutamate receptors (mGluRs) regulate neuronal excitability and synaptic strength. The group I mGluRs, mGluR1 and 5, are widespread in the brain and localize to post-synaptic sites. The Homer protein family regulates group I…

Estrogen, testosterone, and methamphetamine toxicity.

The gonadal steroid hormone, estrogen, can diminish the degree of striatal dopamine depletion resulting from methamphetamine. In this article, we describe the conditions of this estrogen neuroprotection as well as the potential for estrogen and…

Tags: 2006, Animals, Annals of the New York Academy of Sciences, Corpus Striatum/drug effects/metabolism, Dluzen Dean E, Dopamine Agents/*administration & dosage/toxicity, Drug Interactions, Estrogens/*pharmacology, Female, Male, McDermott Janet L, Methamphetamine/*administration & dosage/toxicity, Mice, Testosterone/*pharmacology

Characteristics of emergency medicine program directors.

OBJECTIVES: To characterize emergency medicine (EM) program directors (PDs) and compare the data, where possible, with those from other related published studies. METHODS: An online survey was e-mailed in 2002 to all EM PDs of programs that were…

Screening for adolescent depression in a pediatric emergency department.

OBJECTIVES: To describe the prevalence of depressive symptoms in adolescents presenting to the emergency department (ED) and to describe their demographics and outcomes compared with adolescents endorsing low levels of depressive symptoms. METHODS:…

Tags: *Adolescent Behavior, 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, Adolescent, Adult, Age Distribution, Akron Children's Hospital, Alexander Heather, Christopher Norman C, Comorbidity, Cross-Sectional Studies, Department of Emergency Medicine, Department of Pediatrics, Depression/classification/*diagnosis/*epidemiology, Emergency Service, Female, Fenn Robin L, Hospital/*statistics & numerical data, Hospitalization/statistics & numerical data, Humans, Logistic Models, Luxmore Brett, Male, Mass Screening/*instrumentation/*statistics & numerical data, NEOMED College of Medicine, Ohio/epidemiology, Patient Participation/statistics & numerical data, Pediatrics/*statistics & numerical data, Prevalence, Psychiatric Status Rating Scales, Scott Emily Gale, Transportation of Patients/statistics & numerical data, Wounds and Injuries/epidemiology

Does functional decline prompt emergency department visits and admission in older patients?

BACKGROUND: Older patients may visit the emergency department (ED) when their illness affects their function. OBJECTIVES: To quantify the function of older ED patients, to assess whether functional decline (FD) had occurred, and to determine whether…

Geriatric emergency medicine and the 2006 Institute of Medicine reports from the Committee on the Future of Emergency Care in the U.S. health system.

Three recently published Institute of Medicine reports, Hospital-Based Emergency Care: At the Breaking Point, Emergency Medical Services: At the Crossroads, and Emergency Care for Children: Growing Pains, examined the current state of emergency care…

The medically underserved: who is likely to exercise and why?

Adults who exercise regularly have better health, but only 15% of U.S. adults engage in regular exercise, with some social groups, such as people with lower incomes and women, having even lower rates. This study investigates the rate at which…

Medicine and place: an inquiry.

This essay explores the various places inhabited by doctors and patients, in order to lead doctors to a more complex understanding of their patients' experiences of illness. Using Adam Haslett's "The Good Doctor" (2002), we examine what happens when…

Tags: *Attitude of Health Personnel, *Medicine in Literature, *Physician-Patient Relations, 2006, Aultman Julie M, College of Graduate Studies, Department of Family & Community Medicine, Humans, Medical, NEOMED College of Graduate Studies, NEOMED College of Medicine, Perspectives in biology and medicine, Physician's Role, Physicians/*psychology, Sociology, Wear Delese

Outcomes in pharyngoplasty: a 10-year experience.

OBJECTIVE: The outcomes of 61 patients who underwent a pharyngoplasty for velopharyngeal insufficiency were reviewed to determine potential risk factors for reoperation. DESIGN: This was a retrospective chart review of 61 consecutive patients over…

A Clinical and Ethical Investigation of Pre-medical and Medical Students' Attitudes, Knowledge, and Understanding of HIV.

Ninety-five students participated in a qualitative study examining pre-medical and firstyear medical students' knowledge, understanding, and attitudes surrounding HIV. Participants were given a questionnaire to assess general knowledge and to assess…

Tags: 2006, Aultman Julie M, Borges Nicole J, College of Graduate Studies, Department of Family & Community Medicine, Ethics, HIV, Medical education, Medical education online, NEOMED College of Graduate Studies, NEOMED College of Medicine, Psychosocial

Administrative retreats: a new twist to avoid "administrative isolation".

Tags: *Administrative Personnel, *Interpersonal Relations, 2006, Allen David D, American journal of pharmaceutical education, Calhoun Larry D, Education, Humans, Pharmacy/*organization & administration, Schools

Malignant mesothelioma: a case presentation and review.

Diffuse malignant mesothelioma is the most common primary tumor involving the pleura. Unfortunately, it also poses the most difficulty for physicians to diagnose and treat. Latency from the time of initial asbestos exposure, clinical features of…

The cardiomyopathy of iron deficiency.

Iron-deficiency anemia can have deleterious effects on the heart. Herein, we describe the effects of iron deficiency on the heart as corroborated with electrocardiography, radiology, echocardiography, and cardiac catheterization. We review the…

Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis.

Tags: 2006, Aging/*pathology/physiology, Animals, Bennion P, Biomechanical Phenomena, Bone Matrix/*pathology/physiopathology, Cartilage/*pathology/physiology, Cell Proliferation, Chondrocytes/pathology/physiology, Endoplasmic Reticulum/pathology/physiology, Homeostasis/physiology, Horton W E Jr, Humans, Journal of musculoskeletal & neuronal interactions, Osteoarthritis/*pathology/physiopathology, Yang L

Dermatosis neglecta: a series of case reports and review of other dirty-appearing dermatoses.

Localized scaling and hyperpigmentation is a common finding and often a diagnostic and therapeutic challenge. Dermatosis neglecta (DN) represents a failure to adequately clean or scrub the skin, often in an area of hyperesthesia or prior trauma. We…

Tags: 2006, 80 and over, Adult, Aged, Brodell Robert T, Dermatology online journal, Feldman Steven R, Female, Humans, Lucas Jennifer L, Male, Middle Aged, Skin Care/*methods, Skin Diseases/*etiology/*therapy

Factors leading to radiology career selection: results of the 2004 National Physician Survey.

Data from the 2004 National Physician Survey were used to determine when current Canadian radiologists made their decision to pursue a radiology career and to determine which factors were most influential in their decision. Most respondents reported…

Tags: *Career Choice, *Radiology, 2006, Baerlocher Mark O, Canada, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, Data Collection, Humans, Maj Luke, Medical/psychology, Students, Workforce

Chronic mucocutaneous candidiasis associated with malignant thymoma and systemic lupus erythematosus with hypergammaglobulinemia: a case report and literature review.

Chronic mucocutaneous candidiasis (CMC) is characterized by recurrent candidal infections of the mucous membranes, nails, and skin. Systemic involvement is rare. CMC in adults with coexistent thymoma, benign or malignant, is well-known and is often…

Tags: 2006, Adult, Antifungal Agents/therapeutic use, Candidiasis, Chronic Mucocutaneous/*complications/drug therapy, Cutis, Humans, Hypergammaglobulinemia/*complications, Itraconazole/therapeutic use, Ketoconazole/therapeutic use, Lupus Erythematosus, Male, San Filippo James, Systemic/*complications, Thymoma/*complications, Thymus Neoplasms/*complications

Cutaneous effects of sirolimus in renal transplant recipients.

Cancer is a major cause of death in immunosuppressed transplant patients. Therefore, sirolimus is frequently used in these patients for its immunosuppressive and antineoplastic properties. However, a variety of cutaneous side effects have resulted…

Tags: *Kidney Transplantation, 2006, Department of Family & Community Medicine, Department of Internal Medicine, Drug Eruptions/*etiology, Humans, Immunosuppressive Agents/*adverse effects, Journal of drugs in dermatology : JDD, Libecco James, NEOMED College of Medicine, Sirolimus/*adverse effects, Warino Lindsey

Emergency medical service and in-hospital vital signs as predictors of subsequent PTSD symptom severity in pediatric injury patients.

Background: The present study investigated the extent to which heart rate (HR) levels soon after a traumatic event predicted posttraumatic stress disorder (PTSD) symptom severity assessed 6 weeks and 6 months later in child trauma victims. Methods:…

Tags: 2006, Akron Children's Hospital, CARDIOVASCULAR diseases, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, HEART beat, Journal of Child Psychology & Psychiatry, JUVENILE diseases, MEDICAL emergencies, NEOMED College of Medicine, Nugent Nicole R, PEDIATRIC trauma centers, POST-traumatic stress disorder

Initial physiological responses and perceived hyperarousal predict subsequent emotional numbing in pediatric injury patients.

The present study tested the hypothesis that acute posttraumatic hyperarousal would lead to the development of emotional numbing (EN) symptoms in a pediatric injury population. Eighty-two youths aged 8–18 years were recruited from the emergency…

Tags: 2006, Akron Children's Hospital, Avoidance (Psychology), CHILDREN'S accidents, CHILDREN'S injuries, Christopher Norman C, Delahanty Douglas L, Department of Emergency Medicine, Department of Pediatrics, DEPRESSION in children, EMOTIONS (Psychology), HEART beat, HOSPITAL emergency services, Journal of Traumatic Stress, NEOMED College of Medicine, Nugent Nicole R, POST-traumatic stress disorder, Urine

Sleep Disruptions Mediate the Relationship Between Early Postoperative Pain and Later Functioning Following Total Knee Replacement Surgery.

Despite relatively standardized surgical procedures, patients undergoing total knee replacement (TKR) surgery differ dramatically in the speed of their recovery. Previous research has suggested a relationship between the experience of pain and sleep…

Tags: 2006, Chronic pain, Cremeans-Smith Julie K, Delahanty Douglas L, Greene Kenneth, Journal of Behavioral Medicine, KNEE surgery, Millington Kendra, POSTOPERATIVE pain, Postoperative Period, Sledjeski Eve, sleep, total knee replacement

Evaluation of Nonpharmacologic Methods of Pain and Anxiety Management for Laceration Repair in the Pediatric Emergency Department.

BACKGROUND. Nonpharmacologic interventions, such as distraction, have been shown to be powerful adjuncts in reducing pain and anxiety in children with both acute and chronic painful conditions. There are no controlled studies evaluating these…

Tags: 2006, Akron Children's Hospital, ANXIETY in children, Children, Christopher Norman C, Department of Emergency Medicine, Department of Pediatrics, DISTRACTION (Psychology), Fenn Robin, LETTERS to the editor, NEOMED College of Medicine, PAIN in children, Pain Management, PEDIATRIC emergency services, Pediatrics, Reeves Laurie, Sinha Madhumita

Individual Differences in RIASEC Profile Similarity Across Five Interest Inventories.

The present research indicated substantial variation within the 5 RIASEC (Realistic, Investigative, Artistic, Social, Enterprising, Conventional) profiles obtained by each of 99 individuals who responded to the same 5 interest inventories. The…

Tags: 2006, Counseling, Department of Family & Community Medicine, DIFFERENTIAL psychology, EVALUATION, INDIVIDUAL differences, INTEREST (Psychology), INTEREST inventories, INVENTORIES, Measurement & Evaluation in Counseling & Development, NEOMED College of Medicine, PRODUCT management, Psychological Tests, Savickas Mark L, Taber Brian J

A foreigner in my own country: forgetting the heterogeneity of our national community.

Tags: 2006, American Journal of Bioethics, Aultman JM, College of Graduate Studies, Department of Family & Community Medicine, Ethics, Medical, NEOMED College of Graduate Studies, NEOMED College of Medicine, Ohio, Research by Discipline, Rural Areas, Rural Health Services – Ethical Issues, United States

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