Browse Items · NEOMED Bibliography Database

Interspecific analysis of covariance structure in the masticatory apparatus of galagos.

The primate masticatory apparatus (MA) is a functionally integrated set of features, each of which performs important functions in biting, ingestive, and chewing behaviors. A comparison of morphological covariance structure among species for these MA…

Tags: 2007, American journal of primatology, Animals, Biomechanical Phenomena, Body Size, Diet, Jaw/*anatomy & histology/physiology, Lorisidae/*anatomy & histology/physiology, Mastication/physiology, Multivariate Analysis, Phylogeny, Vinyard Christopher J

Age- and site-specific decline in insulin-like growth factor-I receptor expression is correlated with differential growth plate activity in the mouse hindlimb.

The proximal and distal growth plates of the principal long bones do not contribute equally to longitudinal growth. Most forelimb elongation occurs at the shoulder and wrist, while most hindlimb growth occurs at the knee. This study examined whether…

Tags: 2007, Age Factors, Anatomical record (Hoboken, N.J. : 2007), Animals, Biological Evolution, Growth Plate/*metabolism/physiology, Hindlimb/*growth & development/metabolism, IGF Type 1/*metabolism, Inbred C57BL, King Donna, Lovejoy C Owen, Mice, Proliferating Cell Nuclear Antigen/metabolism, Receptor, Serrat Maria A

Sound transmission in archaic and modern whales: anatomical adaptations for underwater hearing.

The whale ear, initially designed for hearing in air, became adapted for hearing underwater in less than ten million years of evolution. This study describes the evolution of underwater hearing in cetaceans, focusing on changes in sound transmission…

Evolution of hyperphalangy and digit reduction in the cetacean manus.

Cetaceans (whales, dolphins, and porpoises) have a soft tissue flipper that encases most of the forelimb, and elongated digits with an increased number of phalanges (hyperphalangy). In addition, some cetaceans exhibit a reduction in digit number.…

Tags: *Adaptation, *Biological Evolution, 2007, Anatomical record (Hoboken, N.J. : 2007), Animals, Berta Annalisa, Cetacea/*anatomy & histology/physiology, Cooper Lisa Noelle, Dawson Susan D, Department of Anatomy & Neurobiology, Forelimb/*anatomy & histology/physiology, Morphogenesis, NEOMED College of Medicine, Newborn, Phylogeny, Physiological, Reidenberg Joy S

Neuromuscular anatomy and evolution of the cetacean forelimb.

The forelimb of cetaceans (whales, dolphins, and porpoises) has been radically modified during the limb-to-flipper transition. Extant cetaceans have a soft tissue flipper encasing the manus and acting as a hydrofoil to generate lift. The…

Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes.

UNLABELLED: Bile acid synthesis in the liver is regulated by the rate-limiting enzyme cholesterol 7alpha-hydroxylase (CYP7A1). Transcription of the CYP7A1 gene is inhibited by bile acids and cytokines. The rate of bile acid synthesis is reduced…

Tags: 2007, Bile Acids and Salts/*biosynthesis, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*biosynthesis, Cultured, Department of Integrative Medical Sciences, Ellis Ewa, Hepatocyte Growth Factor/*metabolism, Hepatocytes/*metabolism, Hepatology (Baltimore, Md.), Humans, NEOMED College of Medicine, Signal Transduction, Song Kwang-Hoon, Strom Stephen

A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes.

BAG-1 (Bcl-2 associated athanogene-1) is a multifunctional protein, linking cell proliferation, cell death, protein folding, and cell stress. In vivo, BAG-1 is expressed in growth plate and articular cartilage, and the expression of BAG-1 is…

Glutamate and metabotropic glutamate receptors associated with innervation of the uterine cervix during pregnancy: receptor antagonism inhibits c-Fos expression in rat lumbosacral spinal cord at parturition.

Dorsal root ganglia (DRG) neurons connect the spinal cord and uterine cervix, and are activated at parturition with subsequent stimulation of secondary neurons in the spinal dorsal horn and autonomic areas. Neuropeptide neurotransmitters and…

Tags: 2007, Animals, Cervix Uteri/*innervation, Department of Anatomy & Neurobiology, Excitatory Amino Acid Antagonists/pharmacology, Female, Ganglia, Gene Expression Regulation/drug effects/*physiology, Ghosh Chaitali, Glutamates/*metabolism, Hafemeister Jen, Journal of neuroscience research, Lumbosacral Region, Messenger/biosynthesis, Metabotropic Glutamate 5, Metabotropic Glutamate/*metabolism, Miller Kenneth E, NEOMED College of Medicine, Neurons/drug effects, Oncogene Proteins v-fos/metabolism, Papka Raymond E, Parturition/*metabolism, Pregnancy/*metabolism, Pyridines/pharmacology, Rats, Receptor, Receptors, Reverse Transcriptase Polymerase Chain Reaction/methods, RNA, Spinal Cord/drug effects/*physiology, Spinal/cytology, Sprague-Dawley, Storey-Workley Megan, Usip Sharon, Vesicular Glutamate Transport Protein 1/metabolism

A plant lignan, 3'-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells.

Persistent infection with oncogenic human papillomaviruses (HPVs) is the most important factor in the induction of uterine cervical cancer, a leading cause of cancer mortality in women worldwide. Upon cell transformation, continual expression of the…

Tethered cord syndrome in a 24-year-old woman presenting with urinary retention.

We discuss a case of newly diagnosed tethered cord syndrome (TCS) in a

Tags: 2007, Adult, Bologna Raymond, Cerone Jeff, Female, Flora Robert, Hematuria/*etiology, Humans, International urogynecology journal and pelvic floor dysfunction, Laminectomy, Lipoma/complications/surgery, Memo Mark, Neural Tube Defects/*complications/*diagnosis/surgery, Tareen Basir, Urinary Retention/*etiology, Urodynamics/physiology

Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor.

Nasal chondromesenchymal hamartoma (NCMH) is an extremely rare benign pediatric tumor that was described in 1998. Only 19 cases are reported in the literature. We present a 15-year-old girl with nasal obstruction and recurrent sinusitis. Her medical…

Tags: 2007, Adolescent, Cartilage Diseases/*diagnostic imaging/pathology/surgery, Diagnosis, Differential, Esguerra Jorge, Female, Hamartoma/*diagnostic imaging/pathology/surgery, Humans, Johnson Craig, Mesoderm/diagnostic imaging/pathology, Nagaraj Usha, Paranasal Sinus Diseases/*diagnostic imaging/pathology/surgery, Pediatric radiology, Radiography, Wasdahl Daniel, Wurzbach Douglas

Appendicitis in the elderly: a change in the laparoscopic era.

BACKGROUND: Appendicitis in elderly patients is associated with significant morbidity and mortality. Early and correct diagnosis together with minimally invasive surgery can lead to more favorable outcomes than occurred in the prelaparoscopic era.…

CPPD complicating other forms of inflammatory arthritis.

Calcium pyrophosphate deposition (CPPD) disease is confirmed as equally common in rheumatoid arthritis by synovial fluid and macroscopic skeletal examination. Furthermore, differential frequencies in rheumatoid arthritis and spondyloarthropathy…

Tags: *Calcium Pyrophosphate/metabolism, 2007, Arthritis, Bone and Bones/metabolism/pathology, Chondrocalcinosis/*complications/metabolism/pathology, Clinical rheumatology, Female, Humans, Male, Rheumatoid/*complications/metabolism/pathology, Rothschild Bruce, Synovial Fluid/metabolism

Cost-effectiveness analysis of the treatment of large leiomyomas: laparoscopic assisted vaginal hysterectomy versus abdominal hysterectomy.

OBJECTIVE: The purpose of this study was to perform a cost-effectiveness analysis comparing the treatment of large leiomyomas by laparoscopic assisted vaginal hysterectomy (LAVH) versus abdominal hysterectomy (AH). STUDY DESIGN: Twenty consecutive…

Tags: 2007, 80 and over, Adult, Aged, American journal of obstetrics and gynecology, Cost-Benefit Analysis, Fanning James, Female, Fenton Bradford W, Flora Robert, Humans, Hysterectomy, Hysterectomy/*economics, Laparoscopy/economics, Leiomyoma/*surgery, Middle Aged, Mittapalli Raja, Uterine Neoplasms/*surgery, Vaginal/economics

Dual inferior vena cava: two inferior vena cava filters.

The formation of the venous drainage system of the human body is a complex process involving structures forming and regressing in a predefined order. Interruption of any one of these steps results in the formation of a congenital anomaly. Knowledge…

Tags: *Vena Cava Filters, 2007, Aged, Hashmi Zubair A, Humans, Inferior/*abnormalities/anatomy & histology/*surgery, Male, Phlebography, Smaroff Gregory G, The Annals of thoracic surgery, Vena Cava

Structure-activity relationships of pentacycloundecylamines at the

Prompted by our interest in neuroprotective agents with multiple mechanisms of action, we assessed the structure-activity relationship of a series of pentacycloundecylamine derivatives previously shown to have both L-type calcium channel blocking…

Noninvasive ventilation.

Noninvasive positive-pressure ventilation (NPPV) is the delivery of mechanical-assisted breathing without placement of an artificial airway such as an endotracheal tube or tracheostomy. During the first half of 20th century, negative-pressure…

Tags: 2007, Barreiro Timothy J, Chronic Obstructive/*therapy, Continuous Positive Airway Pressure/methods, Critical care clinics, Critical Care/*methods, Department of Internal Medicine, Gemmel David J, Heart Failure/*therapy, Humans, NEOMED College of Medicine, Positive-Pressure Respiration/adverse effects/*methods/trends, Pulmonary Disease, Pulmonary Gas Exchange/physiology, Terminal Care, Ventilator Weaning/*methods

Littoral cell angioma.

Littoral cell angioma (LCA) is an extremely rare primary splenic tumor. There are few MRI and scintigraphic characteristics described. These characteristics may be most helpful in differentiating LCA from other primary vascular tumors. We present a…

Projections from auditory cortex contact ascending pathways that originate in the superior olive and inferior colliculus.

The superior olivary complex (SOC) and inferior colliculus (IC) are targets of cortical projections as well as sources of major ascending auditory pathways. This study examines whether the cortical projections contact cells in the SOC or IC that…

Tags: 2007, Animals, Auditory Cortex/*cytology, Auditory Pathways/*cytology, Department of Anatomy & Neurobiology, Fluorescence, Guinea Pigs, Hearing research, Inferior Colliculi/*cytology, Microscopy, NEOMED College of Medicine, Olivary Nucleus/*cytology, Peterson Diana Coomes, Schofield Brett R, Staining and Labeling/methods

The development of pharmacokinetically enhanced amoxicillin/clavulanate for the management of respiratory tract infections in adults.

Rising levels of resistance amongst the major respiratory pathogens have compromised empiric antimicrobial therapy. This, coupled with a recent lack in availability of novel classes of antibacterials, has led to a need for new approaches to combat…

Tags: 2007, Adult, Amoxicillin-Potassium Clavulanate Combination/*administration & dosage/pharmacokinetics/therapeutic use, Anti-Bacterial Agents/*administration & dosage/pharmacokinetics/therapeutic use, Bacteria/*drug effects/isolation & purification, Community-Acquired Infections/*drug therapy/microbiology, Department of Internal Medicine, File Thomas M Jr, Humans, International journal of antimicrobial agents, NEOMED College of Medicine, Pneumonia/drug therapy/microbiology, Respiratory Tract Infections/*drug therapy/microbiology, Sinusitis/drug therapy/microbiology

The effect of a 12-month longitudinal long-term care rotation on knowledge and attitudes of internal medicine residents about geriatrics.

OBJECTIVE: To determine if participation in a 12-month longitudinal long-term care (LTC) rotation resulted in improved knowledge and attitudes about geriatrics. DESIGN: Longitudinal study with paired measurements. SETTING: A community LTC facility…

Feasibility of the Maylard transverse incision for ovarian cancer cytoreductive surgery.

The vast majority of abdominal incisions used in gynecologic surgery are either transverse or vertical midline. The advantages of a vertical midline incision are considered to be rapid abdominal entry and increased exposure to the abdomen and pelvis.…

Tags: 2007, 80 and over, Aged, Fanning James, Feasibility Studies, Female, Flora Robert F, Gynecologic Surgical Procedures/adverse effects/*methods, Humans, Journal of minimally invasive gynecology, Middle Aged, Ovarian Neoplasms/*surgery, Pruett Allison, Reoperation, Tissue Adhesions/*etiology

Phase I/II prospective trial of autologous platelet tissue graft in gynecologic surgery.

STUDY OBJECTIVE: To perform the original phase I/II trial of autologous platelet tissue graft in gynecologic surgery to evaluate toxicity and efficacy on decreasing pain. DESIGN: Prospective nonrandomized trial (Canadian Task Force classification…

On the use of retrograde tracers for identification of axon collaterals with multiple fluorescent retrograde tracers.

A common method for identifying collateral projections is to inject different retrograde tracers into two targets and examine labeled cells for the presence of both tracers. Double-labeled cells are considered to have collateral projections to the…

Aging and sex differences in striatal dopaminergic function.

In this report the potassium- (30 mM) and amphetamine- (10 microM) stimulated responses of dopamine (DA) and 3,4-dihydroxy phenylacetic acid (DOPAC) from superfused striatal tissue of female and male mice as sampled at 2, 6, 18 and 24 months of age…

Anabolic-androgenic steroids: use and abuse in pediatric patients.

The "win at all costs" mentality fuels athletes to seek performance-enhancing substances, such as anabolic-androgenic steroids, to gain an advantage over their opponents. Nonathletes espouse this same attitude to "win" the battle of attractiveness.…

Tags: *Anabolic Agents/adverse effects, *Androgens/adverse effects, *Doping in Sports/prevention & control, 2007, Adolescent, Adolescent Behavior/drug effects, Child, Congeni Joseph A, Humans, Kerr Julie M, Pediatric clinics of North America, Sports Medicine, Substance Abuse Detection, Substance-Related Disorders/etiology, Testosterone Congeners

Testosterone precursors: use and abuse in pediatric athletes.

The dietary supplements androstenedione, dehydroepiandrosterone, and androstenediol are precursors in the endogenous production of testosterone. The efficacy and safety of these prohormones are not well established but are promoted to have the same…

Tags: *Androstenediols/adverse effects, *Androstenedione/adverse effects, *Dehydroepiandrosterone/adverse effects, *Doping in Sports, 2007, Child, Congeni Joseph A, Dietary Supplements, Humans, Pediatric clinics of North America, Smurawa Troy M, Substance Abuse Detection

Whales originated from aquatic artiodactyls in the Eocene epoch of India.

Although the first ten million years of whale evolution are documented by a remarkable series of fossil skeletons, the link to the ancestor of cetaceans has been missing. It was known that whales are related to even-toed ungulates (artiodactyls), but…

Basal cell adenocarcinoma of minor salivary glands.

Basal cell adenocarcinoma of minor salivary glands is a relatively rare slow-growing tumor with an infiltrating growth pattern. The infiltrating growth pattern and likelihood of vascular and perineural involvement distinguishes basal cell…

Tags: 2007, Adenocarcinoma/*diagnosis/radiotherapy/surgery, Adenoid Cystic/diagnosis, Adenoma/diagnosis, Archives of pathology & laboratory medicine, Carcinoma, Chang Yilan L, Combined Modality Therapy, Diagnosis, Differential, Farrell Tisha, Humans, Minor/*pathology/surgery, Salivary Gland Neoplasms/*diagnosis/radiotherapy/surgery, Salivary Glands, Squamous Cell/diagnosis

A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.

BACKGROUND & AIMS: Inhibition of cholesterol 7alpha-hydroxylase (CYP7A1) by bile acids and inflammatory cytokines provides an important mechanism to protect hepatocytes from bile acid toxicity during cholestasis. Transforming growth factor beta1…

Fresh-frozen osteochondral allograft reconstruction of a giant cell tumor of the talus.

The use of fresh-frozen osteochondral allografts has been reported for the treatment of talar fractures, osteochondral lesions, and tumors of the calcaneus. Currently, we are unaware of any reports in the literature addressing the use of fresh-frozen…

Tags: *Bone Transplantation, *Talus, 2007, Adult, Bone Neoplasms/*surgery, Female, Freezing, Giant Cell Tumor of Bone/*surgery, Grossman Jordan P, Homologous, Humans, Leeson Mark C, Recurrence, Schoenfeld Andrew J, The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, Transplantation

Complex fractures of the tibial plateau.

Tags: 2007, Bone Transplantation, Cementation, External Fixators, Fracture Fixation, Hooks Bryan, Humans, Internal, Leg Injuries/therapy, Ligaments/injuries, Magnetic Resonance Imaging, Pesantez Rodrigo, Radiography, Soft Tissue Injuries/therapy, The journal of knee surgery, Tibial Fractures/*classification/diagnostic imaging/surgery, Tibial Meniscus Injuries, Ziran Bruce H

Alterations in the mechanical properties and composition of skin in human growth hormone transgenic mice.

Growth hormone is known to stimulate connective tissue, but the degree to which it influences skin biomechanical properties is unclear. This study tested the hypothesis that human growth hormone transgene expression changes the material properties…

Tags: *Biomechanical Phenomena, *Skin Physiological Phenomena, 2007, Animals, Connective tissue research, Elasticity, Female, Human Growth Hormone/*genetics, Humans, King Donna, Male, Mechanical, Mice, Serrat Maria A, Sex Characteristics, Skin/anatomy & histology/*chemistry, Stress, Transgenic, Vinyard Christopher J

Retheorizing sexual harassment in medical education: women students' perceptions at five U.S. medical schools.

BACKGROUND: The literature consistently reports that sexual harassment occurs with regularity in medical education, mostly in clinical settings, and most of it goes unreported. Reasons for nonreporting include the fear of retaliation, a reluctance to…

The impact of exercise on activities of daily living and quality of life: a primary care physician's perspective.

Evaluation of the environment of patients is an important function of the primary care physician and assists the caregiver in providing an improved quality of life for one's patients. In addition to data collection and therapy, assessment of both the…

Tags: *Activities of Daily Living, *Physician's Role, *Primary Health Care, *Quality of Life, 2007, Aged, Belfer Mark H, Chronic Obstructive/physiopathology/*therapy, COPD, Exercise/*physiology, Female, Humans, Male, Middle Aged, Pulmonary Disease

Reminiscences of the early days of getting to know one of man's best friends.

Tags: *DNA Viruses/genetics/pathogenicity/physiology, *RNA Viruses/genetics/pathogenicity/physiology, 2007, 20th Century, 21st Century, Animals, History, Interferons/*history, Joklik Wolfgang K Bill, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, United States, Virology/*history

Resveratrol inhibition of Propionibacterium acnes.

OBJECTIVES: To evaluate the effects of the anti-inflammatory hydroxystilbene, resveratrol, on Propionibacterium acnes growth. METHODS: Three different strains of P. acnes were tested against resveratrol at concentrations between 0 and 200 mg/L.…

Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.

OBJECTIVES: Short-course therapy has been advocated for the treatment of community-acquired pneumonia (CAP). We compared the efficacy and safety of 5 and 7 day courses of gemifloxacin for outpatient treatment of mild-moderate CAP. PATIENTS AND…

Lack of bone stiffness/strength contribution to osteoarthritis–evidence for primary role of cartilage damage.

OBJECTIVES: This study was performed to assess osseous contributions to osteoarthritis, obviating the analysis challenges presented by confounding factors in humans and rarity of osteoarthritis in free-ranging mammals. METHODS: Frequency of…

Tags: 2007, Animal, Animals, Articular/physiopathology, Biomechanical Phenomena, Bird Diseases/*physiopathology, Birds, Bone and Bones/*physiopathology, Cartilage, Disease Models, Mechanical, Osteoarthritis/*physiopathology/*veterinary, Panza R K, Rheumatology (Oxford, England), Rothschild B M, Species Specificity, Stress

Increased intraabdominal pressure in abdominoplasty: delineation of risk factors.

BACKGROUND: Abdominoplasty is associated with a 1.1 percent risk of deep venous thrombosis. This has been attributed to rectus plication causing intraabdominal hypertension, known to effect decreased venous return, venous stasis, and thus thrombosis.…

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