1
40
287
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
2-2
Issue
21
Volume
126
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Failure Of Regenerative Cell-based Therapy To Stimulate Coronary Collateral Growth In A Rat Model Of Metabolic Syndrome
Publisher
An entity responsible for making the resource available
Circulation
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-11
Subject
The topic of the resource
Arteriogenesis; Cardiovascular System & Cardiology; Collateral circulation; Metabolic; oxidative stress; Stem cell therapy; syndrome
Creator
An entity primarily responsible for making the resource
Logan S; Chilian W M; Ohanyan V A; Stevanov K; Enrick M; Kolz C L; Yin L Y
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Arteriogenesis
Cardiovascular System & Cardiology
Chilian W M
Circulation
Collateral Circulation
Enrick M
Journal Article or Conference Abstract Publication
Kolz C L
Logan S
Metabolic
Ohanyan V A
Oxidative Stress
Stem cell therapy
Stevanov K
Syndrome
Yin L Y
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.brainres.2012.10.029" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.brainres.2012.10.029</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
133-139
Volume
1489
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Ngp1-01, A Multi-targeted Polycyclic Cage Amine, Attenuates Brain Endothelial Cell Death In Iron Overload Conditions
Publisher
An entity responsible for making the resource available
Brain Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
activator; barrier; calcium channels; channels provide; intracerebral hemorrhage; Iron-overload; neurodegeneration; neurodegenerative disorders; neuroprotection; Neurosciences & Neurology; Nimodipine; parkinsons-disease; permeability; rat-brain; toxicity; transport; Vascular endothelial cells; Voltage-gated calcium channel
Creator
An entity primarily responsible for making the resource
Lockman J A; Geldenhuys W J; Jones-Higgins M R; Patrick J D; Allen D D; Van der Schyf C J
Description
An account of the resource
Development and progression of neurodegenerative disorders have, amongst other potential causes, been attributed to a disruption of iron regulatory mechanisms and iron accumulation. Excess extracellular iron may enter cells via nontraditional routes such as voltage-gated calcium channels and N-methyl-D-aspartate (NMDA) receptors leading to intracellular oxidative damage and ultimately mitochondrial failure. Nimodipine, an L-type calcium channel blocker has been shown to reduce iron-induced toxicity in neuronal and brain endothelial cells. Our current study investigates NGP1-01, a multimodal drug acting as an antagonist at both the NMDA receptor and the L-type calcium channel. Our previous studies support NGP1-01. as a promising neuroprotective agent in diseases involving calcium-related excitotoxicity. We demonstrate here that NGP1-01 (1 and 10 mu M) pretreatment abrogates the effects of iron overload in brain endothelial cells protecting cellular viability. Both concentrations of NGP1-01 were found to attenuate iron-induced reduction in cellular viability to a similar extent, and were statistically significant. To further verify the mechanism, the L-type calcium channel agonist FPL 64176 was administered to promote iron uptake. Addition of NGP1-01 dose-dependently reduced FPL 64176 stimulated uptake of iron. These data support further evaluation of NGP1-01 as a neuroprotective agent, not only in diseases associated with excitotoxicity, but also in those of iron overload. (C) 2012 Elsevier B.V. All rights reserved.
Identifier
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<a href="http://doi.org/10.1016/j.brainres.2012.10.029" target="_blank" rel="noreferrer noopener">10.1016/j.brainres.2012.10.029</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
activator
Allen D D
barrier
Brain research
Calcium Channels
channels provide
Geldenhuys W J
intracerebral hemorrhage
Iron-overload
Jones-Higgins M R
Journal Article or Conference Abstract Publication
Lockman J A
Neurodegeneration
neurodegenerative disorders
Neuroprotection
Neurosciences & Neurology
nimodipine
parkinsons-disease
Patrick J D
Permeability
rat-brain
toxicity
transport
Van der Schyf C J
Vascular endothelial cells
Voltage-gated calcium channel
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s11064-011-0591-2" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s11064-011-0591-2</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
134-142
Issue
1
Volume
37
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Differential Effect Of Nimodipine In Attenuating Iron-induced Toxicity In Brain- And Blood-brain Barrier-associated Cell Types
Publisher
An entity responsible for making the resource available
Neurochemical Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-01
Subject
The topic of the resource
Astrocytes; Biochemistry & Molecular Biology; central-nervous-system; cerebrospinal-fluid; cultured astrocytes; intracerebral hemorrhage; Iron in brain; Metal toxicity; Neurodegenerative diseases; neurodegenerative disorders; neurons; Neurosciences & Neurology; Nimodipine; oxidative; parkinsons-disease; redox-active iron; stress; substantia-nigra; transferrin receptor; Vascular endothelial cells
Creator
An entity primarily responsible for making the resource
Lockman J A; Geldenhuys W J; Bohn K A; DeSilva S F; Allen D D; Van der Schyf C J
Description
An account of the resource
Metal homeostasis is increasingly being evaluated as a therapeutic target in stroke and neurodegenerative diseases. Metal dysregulation has been shown to lead to protein aggregation, plaque formation and neuronal death. In 2007, we first reported that voltage-gated calcium channels act as a facile conduit for the entry of free ferrous (Fe2+) ions into neurons. Herein, we evaluate differential iron toxicity to central nervous system cells and assess the ability of the typical L-type voltage-gated calcium channel blocker nimodipine to attenuate iron-induced toxicity. The data demonstrate that iron sulfate induces a dose-dependent decrease in cell viability in rat brain endothelial cells (RBE4; LC50 = 150 mu M), neuronal cells (Neuro-2 alpha neuroblastoma; LC50 = 400 mu M), and in astrocytes (DI TNC1; LC50 = 1.1 mM). Pre-treatment with nimodipine prior to iron sulfate exposure provided a significant (P < 0.05) increase in viable cell numbers for RBE4 (2.5-fold), Neuro2-alpha (similar to 2-fold), and nearly abolished toxicity in primary neurons. Astrocytes were highly resistant to iron toxicity compared to the other cell types tested and nimodipine had no (P > 0.05) protective effect in these cells. The data demonstrate variable susceptibility to iron overload conditions in different cell types of the brain and suggest that typical L-type voltage-gated calcium channel blockers (here represented by nimodipine), may serve as protective agents in conditions involving iron overload, particularly in cell types highly susceptible to iron toxicity.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s11064-011-0591-2" target="_blank" rel="noreferrer noopener">10.1007/s11064-011-0591-2</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Allen D D
Astrocytes
Biochemistry & Molecular Biology
Bohn K A
central-nervous-system
cerebrospinal-fluid
cultured astrocytes
DeSilva S F
Geldenhuys W J
intracerebral hemorrhage
Iron in brain
Journal Article or Conference Abstract Publication
Lockman J A
Metal toxicity
Neurochemical Research
Neurodegenerative Diseases
neurodegenerative disorders
Neurons
Neurosciences & Neurology
nimodipine
oxidative
parkinsons-disease
redox-active iron
Stress
substantia-nigra
transferrin receptor
Van der Schyf C J
Vascular endothelial cells
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ygcen.2012.07.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ygcen.2012.07.011</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
562-572
Issue
3
Volume
178
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Knockdown Of Leptin A Expression Dramatically Alters Zebrafish Development
Publisher
An entity responsible for making the resource available
General and Comparative Endocrinology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-09
Subject
The topic of the resource
atlantic salmon; Auditory; bhlh genes; bone; carp cyprinus-carpio; cell fate specification; central-nervous-system; cloning; danio-rerio; differentiation; Endocrinology & Metabolism; gene; metabolism; n-cadherin; receptor; sensory ganglia; Visual; visual-system
Creator
An entity primarily responsible for making the resource
Liu Q; Dalman M; Chen Y; Akhter M; Brahmandam S; Patel Y; Lowe J; Thakkar M; Gregory A V; Phelps D; Riley C; Londraville R L
Description
An account of the resource
Using morpholino antisense oligonucleotide (MO) technology, we blocked leptin A or leptin receptor expression in embryonic zebrafish, and analyzed consequences of leptin A knock-down on fish development. Embryos injected with leptin A or leptin receptor MOs (leptin A or leptin receptor morphants) had smaller bodies and eyes, undeveloped inner ear, enlarged pericardial cavity, curved body and/or tail and larger yolk compared to control embryos of the same stages. The defects persisted in 6-9 days old larvae. We found that blocking leptin A function had little effect on the development of early brain (1 day old), but differentiation of both the morphant dorsal brain and retinal cells was severely disrupted in older (2 days old) embryos. Despite the enlarged pericardial cavity, differentiation of cardiac cells appeared to be similar to control embryos. Formation of the morphants' inner ear is also severely disrupted, which corroborates existing reports of leptin receptor expression in inner ear of both zebrafish and mammals. Co-injection of leptin A MO and recombinant leptin results in partial rescue of the wild-type phenotype. Our results suggest that leptin A plays distinct roles in zebrafish development. (c) 2012 Elsevier Inc. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.ygcen.2012.07.011" target="_blank" rel="noreferrer noopener">10.1016/j.ygcen.2012.07.011</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Akhter M
atlantic salmon
Auditory
bhlh genes
Bone
Brahmandam S
carp cyprinus-carpio
cell fate specification
central-nervous-system
Chen Y
Cloning
Dalman M
danio-rerio
differentiation
Endocrinology & Metabolism
gene
General and Comparative Endocrinology
Gregory A V
Journal Article or Conference Abstract Publication
Liu Q
Londraville R L
Lowe J
Metabolism
n-cadherin
Patel Y
Phelps D
Receptor
Riley C
sensory ganglia
Thakkar M
Visual
visual-system
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
539A-539A
Volume
56
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A Novel Microrna 33a-mediated Regulation Of Hepatic Bile Acid And Cholesterol Metabolism
Publisher
An entity responsible for making the resource available
Hepatology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
Gastroenterology & Hepatology
Creator
An entity primarily responsible for making the resource
Li T G; Francl J M; Boehme S M; Chiang J
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Boehme S M
Chiang J
Francl J M
Gastroenterology & Hepatology
Hepatology
Journal Article or Conference Abstract Publication
Li T G
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s11908-011-0224-6" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s11908-011-0224-6</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
33-40
Issue
1
Volume
14
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Title
A name given to the resource
Update On Cytomegalovirus Infections Of The Gastrointestinal System In Solid Organ Transplant Recipients
Publisher
An entity responsible for making the resource available
Current Infectious Disease Reports
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-02
Subject
The topic of the resource
CMV; Cytomegalovirus; Gastrointestinal infection; Infectious Diseases; Solid organ transplant
Creator
An entity primarily responsible for making the resource
Lemonovich T L; Watkins R R
Description
An account of the resource
Cytomegalovirus (CMV) infection of the gastrointestinal tract is the most common manifestation of tissue-invasive CMV disease, and is a significant cause of morbidity and mortality in the solid organ transplantation (SOT) recipient. In addition to the direct effects of the infection, its indirect effects on allograft function, risk for other opportunistic infections, and mortality are significant in this population. The most common clinical syndromes are esophagitis, colitis, and hepatitis; however, infection can occur anywhere in the gastrointestinal tract. Diagnosis is usually by histopathology or viral culture of tissue specimens; molecular assays also often have a role. Antivirals are the cornerstone of therapy for gastrointestinal tract CMV disease and complications such as recurrent infection and antiviral resistance are not uncommon. Prevention with antiviral prophylaxis or preemptive therapy is important. This review summarizes recent data regarding the clinical manifestations, diagnosis, treatment, and prevention of gastrointestinal tract CMV infection in the SOT population.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s11908-011-0224-6" target="_blank" rel="noreferrer noopener">10.1007/s11908-011-0224-6</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
CMV
Current infectious disease reports
Cytomegalovirus
Department of Internal Medicine
Gastrointestinal infection
Infectious Diseases
Journal Article or Conference Abstract Publication
Lemonovich T L
NEOMED College of Medicine
Solid organ transplant
Watkins R R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0041923" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0041923</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
9-9
Issue
7
Volume
7
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mycobacterium Tuberculosis Complex Lipid Virulence Factors Preserved In The 17,000-year-old Skeleton Of An Extinct Bison, Bison Antiquus
Publisher
An entity responsible for making the resource available
Plos One
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-07
Subject
The topic of the resource
acquired genomic islands; dna; evolution; homo-erectus; Science & Technology - Other Topics; trehalose
Creator
An entity primarily responsible for making the resource
Lee O Y C; Wu H H T; Donoghue H D; Spigelman M; Greenblatt C L; Bull I D; Rothschild B M; Martin L D; Minnikin D E; Besra G S
Description
An account of the resource
Tracing the evolution of ancient diseases depends on the availability and accessibility of suitable biomarkers in archaeological specimens. DNA is potentially information-rich but it depends on a favourable environment for preservation. In the case of the major mycobacterial pathogens, Mycobacterium tuberculosis and Mycobacterium leprae, robust lipid biomarkers are established as alternatives or complements to DNA analyses. A DNA report, a decade ago, suggested that a 17,000-year-old skeleton of extinct Bison antiquus, from Natural Trap Cave, Wyoming, was the oldest known case of tuberculosis. In the current study, key mycobacterial lipid virulence factor biomarkers were detected in the same two samples from this bison. Fluorescence high-performance liquid chromatography (HPLC) indicated the presence of mycolic acids of the mycobacterial type, but they were degraded and could not be precisely correlated with tuberculosis. However, pristine profiles of C-29, C-30 and C-32 mycocerosates and C-27 mycolipenates, typical of the Mycobacterium tuberculosis complex, were recorded by negative ion chemical ionization gas chromatography mass spectrometry of pentafluorobenzyl ester derivatives. These findings were supported by the detection of C-34 and C-36 phthiocerols, which are usually esterified to the mycocerosates. The existence of Pleistocene tuberculosis in the Americas is confirmed and there are many even older animal bones with well-characterised tuberculous lesions similar to those on the analysed sample. In the absence of any evidence of tuberculosis in human skeletons older than 9,000 years BP, the hypothesis that this disease evolved as a zoonosis, before transfer to humans, is given detailed consideration and discussion.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1371/journal.pone.0041923" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0041923</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
acquired genomic islands
Besra G S
Bull I D
DNA
Donoghue H D
Evolution
Greenblatt C L
homo-erectus
Journal Article or Conference Abstract Publication
Lee O Y C
Martin L D
Minnikin D E
PloS one
Rothschild B M
Science & Technology - Other Topics
Spigelman M
trehalose
Wu H H T
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.00731.2011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.00731.2011</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
H1410-H1422
Issue
7
Volume
302
Search for Full-text
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Biphasic Modulation Of The Mitochondrial Electron Transport Chain In Myocardial Ischemia And Reperfusion
Publisher
An entity responsible for making the resource available
American Journal of Physiology-Heart and Circulatory Physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Cardiovascular System & Cardiology; cytochrome-c-oxidase; energy-metabolism; injury; nadh dehydrogenase; oxidative modification; oxygen-free-radicals; Physiology; postischemic myocardium; protein biosynthesis; rat-heart mitochondria; reactive oxygen species; transfer complex-i; translational control
Creator
An entity primarily responsible for making the resource
Lee H L; Chen C L; Yeh S T; Zweier J L; Chen Y R
Description
An account of the resource
Lee HL, Chen CL, Yeh ST, Zweier JL, Chen YR. Biphasic modulation of the mitochondrial electron transport chain in myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 302: H1410-H1422, 2012. First published January 20, 2012; doi: 10.1152/ajpheart.00731.2011.-Mitochondrial electron transport chain (ETC) is the major source of reactive oxygen species during myocardial ischemia-reperfusion (I/R) injury. Ischemic defect and reperfusion-induced injury to ETC are critical in the disease pathogenesis of postischemic heart. The properties of ETC were investigated in an isolated heart model of global I/R. Rat hearts were subjected to ischemia for 30 min followed by reperfusion for 1 h. Studies of mitochondrial function indicated a biphasic modulation of electron transfer activity (ETA) and ETC protein expression during I/R. Analysis of ETAs in the isolated mitochondria indicated that complexes I, II, III, and IV activities were diminished after 30 min of ischemia but increased upon restoration of flow. Immunoblotting analysis and ultrastructural analysis with transmission electron microscopy further revealed marked downregulation of ETC in the ischemic heart and then upregulation of ETC upon reperfusion. No significant difference in the mRNA expression level of ETC was detected between ischemic and postischemic hearts. However, reperfusion-induced ETC biosynthesis in myocardium can be inhibited by cycloheximide, indicating the involvement of translational control. Immunoblotting analysis of tissue homogenates revealed a similar profile in peroxisome proliferator-activated receptor-gamma coactivator-1 alpha expression, suggesting its essential role as an upstream regulator in controlling ETC biosynthesis during I/R. Significant impairment caused by ischemic and postischemic injury was observed in the complexes I-III. Analysis of NADH ferricyanide reductase activity indicated that injury of flavoprotein subcomplex accounts for 50% decline of intact complex I activity from ischemic heart. Taken together, our findings provide a new insight into the molecular mechanism of I/R-induced mitochondrial dysfunction.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.00731.2011" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.00731.2011</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
American Journal of Physiology-Heart and Circulatory Physiology
Cardiovascular System & Cardiology
Chen C L
Chen Y R
cytochrome-c-oxidase
energy-metabolism
Injury
Journal Article or Conference Abstract Publication
Lee H L
nadh dehydrogenase
oxidative modification
oxygen-free-radicals
Physiology
postischemic myocardium
Protein Biosynthesis
rat-heart mitochondria
reactive oxygen species
transfer complex-i
translational control
Yeh S T
Zweier J L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
2-2
Volume
23
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Delayed Bone Development In A Preeclampsia Mouse Model
Publisher
An entity responsible for making the resource available
Molecular Biology of the Cell
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012
Subject
The topic of the resource
Cell Biology
Creator
An entity primarily responsible for making the resource
Lababidi S L; Nakhla S; Al-Ghafiy M; Rafii A; Davisson R L; Safadi F
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Al-Ghafiy M
Cell Biology
Davisson R L
Journal Article or Conference Abstract Publication
Lababidi S L
Molecular Biology of the Cell
Nakhla S
Rafii A
Safadi F
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/hep.25740" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/hep.25740</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1034-1043
Issue
3
Volume
56
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mechanism Of Tissue-specific Farnesoid X Receptor In Suppressing The Expression Of Genes In Bile-acid Synthesis In Mice
Publisher
An entity responsible for making the resource available
Hepatology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-09
Subject
The topic of the resource
7-alpha-hydroxylase; activation; biosynthesis; cholesterol; feedback-regulation; fxr; Gastroenterology & Hepatology; homeostasis; molecular-basis; orphan nuclear receptor; signal; small heterodimer partner
Creator
An entity primarily responsible for making the resource
Kong B; Wang L; Chiang J Y L; Zhang Y C; Klaassen C D; Guo G L
Description
An account of the resource
Activation of farnesoid X receptor (Fxr, Nr1h4) is a major mechanism in suppressing bile-acid synthesis by reducing the expression levels of genes encoding key bile-acid synthetic enzymes (e.g., cytochrome P450 [CYP]7A1/Cyp7a1 and CYP8B1/Cyp8b1). FXR-mediated induction of hepatic small heterodimer partner (SHP/Shp, Nr0b2) and intestinal fibroblast growth factor 15 (Fgf15; FGF19 in humans) has been shown to be responsible for this suppression. However, the exact contribution of Shp/Fgf15 to this suppression, and the associated cell-signaling pathway, is unclear. By using novel genetically modified mice, the current study showed that the intestinal Fxr/Fgf15 pathway was critical for suppressing both Cyp7a1 and Cyp8b1 gene expression, but the liver Fxr/Shp pathway was important for suppressing Cyp8b1 gene expression and had a minor role in suppressing Cyp7a1 gene expression. Furthermore, in vivo administration of Fgf15 protein to mice led to a strong activation of extracellular signal-related kinase (ERK) and, to a smaller degree, Jun N-terminal kinase (JNK) in the liver. In addition, deficiency of either the ERK or JNK pathway in mouse livers reduced the basal, but not the Fgf15-mediated, suppression of Cyp7a1 and Cyp8b1 gene expression. However, deficiency of both ERK and JNK pathways prevented Fgf15-mediated suppression of Cyp7a1 and Cyp8b1 gene expression. Conclusion: The current study clearly elucidates the underlying molecular mechanism of hepatic versus intestinal Fxr in regulating the expression of genes critical for bile-acid synthesis and hydrophobicity in the liver. (HEPATOLOGY 2012;56:10341043)
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/hep.25740" target="_blank" rel="noreferrer noopener">10.1002/hep.25740</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
7-alpha-hydroxylase
activation
biosynthesis
Chiang J Y L
Cholesterol
feedback-regulation
FXR
Gastroenterology & Hepatology
Guo G L
Hepatology
Homeostasis
Journal Article or Conference Abstract Publication
Klaassen C D
Kong B
molecular-basis
orphan nuclear receptor
signal
small heterodimer partner
Wang L
Zhang Y C
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-1
Volume
26
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Trpv1 Channels In The Heart: A Novel Redox Sensor?
Publisher
An entity responsible for making the resource available
Faseb Journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Creator
An entity primarily responsible for making the resource
Kmetz J G; Ohanyan V; Enrick M; Kang P T; Chen C L; Chen Y R; Bratz I N
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Biochemistry & Molecular Biology
Bratz I N
Cell Biology
Chen C L
Chen Y R
Enrick M
Faseb Journal
Journal Article or Conference Abstract Publication
Kang P T
Kmetz J G
Life Sciences & Biomedicine - Other
Ohanyan V
Topics
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.gene.2011.11.013" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.gene.2011.11.013</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
349-353
Issue
2
Volume
492
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Evolutionary Changes Of The Importance Of Olfaction In Cetaceans Based On The Olfactory Marker Protein Gene
Publisher
An entity responsible for making the resource available
Gene
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-01
Subject
The topic of the resource
Aquatic adaptation; deletion causes; Echolocation; Eocene whale; Filter-feeder; Genetics & Heredity; india; marine mammals; neurons; nucleotide; OMP; sea; sequences; whales
Creator
An entity primarily responsible for making the resource
Kishida T; Thewissen J G M
Description
An account of the resource
Odontocetes and mysticetes are two extant suborders of cetaceans. It is reported that the former have no sense of olfaction, while the latter can smell in air. To explain the ecological reason why mysticetes still retain their sense of smell, two hypotheses have been proposed - the echolocation-priority hypothesis, which assumes that the acquisition of echolocation causes the reduction of the importance of olfaction, and the filter-feeder hypothesis, which assumes that olfactory ability is important for filter-feeders to locate their prey because clouds of plankton give off a peculiar odor. The olfactory marker protein (OMP) is almost exclusively expressed in vertebrate olfactory receptor neurons, and is considered to play important roles in olfactory systems. In this study, full-length open reading frames of OMP genes were identified in 6 cetacean species and we analyzed the nonsynonymous to synonymous substitution rate ratio based on the maximum likelihood method. The evolutionary changes of the selective pressures on OMP genes did fit better to the filter-feeder hypothesis than to the echolocation-priority hypothesis. In addition, no pseudogenization mutations are found in all five odontocetes OMP genes investigated in this study. It may suggest that OMP retains some function even in 'anosmic' odontocetes. (C) 2011 Elsevier B.V. All rights reserved.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.gene.2011.11.013" target="_blank" rel="noreferrer noopener">10.1016/j.gene.2011.11.013</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Aquatic adaptation
deletion causes
Echolocation
Eocene whale
Filter-feeder
gene
Genetics & Heredity
India
Journal Article or Conference Abstract Publication
Kishida T
marine mammals
Neurons
nucleotide
OMP
SEA
sequences
Thewissen J G M
WHALES
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1074/jbc.M112.339887" target="_blank" rel="noreferrer noopener">http://doi.org/10.1074/jbc.M112.339887</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
37098-37108
Issue
44
Volume
287
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Orphan Nuclear Receptor Small Heterodimer Partner Negatively Regulates Growth Hormone-mediated Induction Of Hepatic Gluconeogenesis Through Inhibition Of Signal Transducer And Activator Of Transcription 5 (stat5) Transactivation
Publisher
An entity responsible for making the resource available
Journal of Biological Chemistry
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
ampk; ataxia-telangiectasia; atm; Biochemistry & Molecular Biology; expression; Glucose; glucose-6-phosphatase gene; involvement; metformin; protein kinase; shp
Creator
An entity primarily responsible for making the resource
Kim Y D; Li T G; Ahn S W; Kim D K; Lee J M; Hwang S L; Kim Y H; Lee C H; Lee I K; Chiang J Y L; Choi H S
Description
An account of the resource
Growth hormone (GH) is a key metabolic regulator mediating glucose and lipid metabolism. Ataxia telangiectasia mutated (ATM) is a member of the phosphatidylinositol 3-kinase superfamily and regulates cell cycle progression. The orphan nuclear receptor small heterodimer partner (SHP: NR0B2) plays a pivotal role in regulating metabolic processes. Here, we studied the role of ATM on GH-dependent regulation of hepatic gluconeogenesis in the liver. GH induced phosphoenolpyruvate carboxykinase (PEPCK) and glucose 6-phosphatase gene expression in primary hepatocytes. GH treatment and adenovirus-mediated STAT5 overexpression in hepatocytes increased glucose production, which was blocked by a JAK2 inhibitor, AG490, dominant negative STAT5, and STAT5 knockdown. We identified a STAT5 binding site on the PEPCK gene promoter using reporter assays and point mutation analysis. Up-regulation of SHP by metformin-mediated activation of the ATM-AMP-activated protein kinase pathway led to inhibition of GH-mediated induction of hepatic gluconeogenesis, which was abolished by an ATM inhibitor, KU-55933. Immunoprecipitation studies showed that SHP physically interacted with STAT5 and inhibited STAT5 recruitment on the PEPCK gene promoter. GH-induced hepatic gluconeogenesis was decreased by either metformin or Ad-SHP, whereas the inhibition by metformin was abolished by SHP knockdown. Finally, the increase of hepatic gluconeogenesis following GH treatment was significantly higher in the liver of SHP null mice compared with that of wildtype mice. Overall, our results suggest that the ATM-AMP-activated protein kinase-SHP network, as a novel mechanism for regulating hepatic glucose homeostasis via a GH-dependent pathway, may be a potential therapeutic target for insulin resistance.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1074/jbc.M112.339887" target="_blank" rel="noreferrer noopener">10.1074/jbc.M112.339887</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Ahn S W
AMPK
ataxia-telangiectasia
atm
Biochemistry & Molecular Biology
Chiang J Y L
Choi H S
expression
GLUCOSE
glucose-6-phosphatase gene
Hwang S L
involvement
Journal Article or Conference Abstract Publication
Journal of Biological Chemistry
Kim D K
Kim Y D
Kim Y H
Lee C H
Lee I K
Lee J M
Li T G
metformin
protein kinase
SHP
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4293/108680812x13427982376103" target="_blank" rel="noreferrer noopener">http://doi.org/10.4293/108680812x13427982376103</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
341-344
Issue
3
Volume
16
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Teaching And Learning Of Surgery
Publisher
An entity responsible for making the resource available
Jsls-Journal of the Society of Laparoendoscopic Surgeons
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-07
Subject
The topic of the resource
acquisition; memory; Surgery
Creator
An entity primarily responsible for making the resource
Kavic M S
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.4293/108680812x13427982376103" target="_blank" rel="noreferrer noopener">10.4293/108680812x13427982376103</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
acquisition
Journal Article or Conference Abstract Publication
Jsls-Journal of the Society of Laparoendoscopic Surgeons
Kavic M S
Memory
Surgery
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-1
Issue
21
Volume
126
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Oxidant Stress-induced Protein Thiyl Radical Is Associated To Enhancement Of Complex I S-glutathionylation In The Enos(-/-) Murine Heart
Publisher
An entity responsible for making the resource available
Circulation
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-11
Subject
The topic of the resource
Cardiovascular System & Cardiology; Mitochondria; Myocardium; nitric-oxide synthase; Redox; Super oxide
Creator
An entity primarily responsible for making the resource
Kang P T; Chen C L; Chen Y R
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Cardiovascular System & Cardiology
Chen C L
Chen Y R
Circulation
Journal Article or Conference Abstract Publication
Kang P T
Mitochondria
Myocardium
nitric-oxide synthase
Redox
Super oxide
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/cmdc.201100559" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/cmdc.201100559</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
375-384
Issue
3
Volume
7
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Polycyclic Cage Structures As Lipophilic Scaffolds For Neuroactive Drugs
Publisher
An entity responsible for making the resource available
Chemmedchem
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-03
Subject
The topic of the resource
Alzheimer's disease; apoptosis; benzodiazepine-receptors; biological activity; cage compounds; calcium-antagonists; carbonic-anhydrase inhibitors; d-aspartate receptor; drug design; fluorescent ligands; monoamine-oxidase-b; neuroprotection; nitric-oxide; parkinsons-disease; Pharmacology & Pharmacy; sigma-receptors
Creator
An entity primarily responsible for making the resource
Joubert J; Geldenhuys W J; Van der Schyf C J; Oliver D W; Kruger H G; Govender T; Malan S F
Description
An account of the resource
Polycyclic cage scaffolds have been successfully used in the development of numerous lead compounds demonstrating activity in the central nervous system (CNS). Several neurodegenerative diseases, such as Alzheimers disease, Parkinsons disease, Huntingtons disease, schizophrenia, and stroke, as well as drug abuse, can be modulated with polycyclic cage derivatives. These cage moieties, including adamantane and pentacycloundecane derivatives, improve the pharmacokinetic and pharmacodynamic properties of conjugated parent drugs and serve as an important scaffold in the design of therapeutically active agents for the treatment of neurological disorders. In this Minireview, we focus on the recent developments in the field of polycyclic cage compounds, as well as the relationship between the lipophilic character of these cage-derived drugs and the ability of such compounds to target and reach the CNS and improve the pharmacodynamic properties of compounds conjugated to it.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/cmdc.201100559" target="_blank" rel="noreferrer noopener">10.1002/cmdc.201100559</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Alzheimer's disease
Apoptosis
benzodiazepine-receptors
biological activity
cage compounds
calcium-antagonists
carbonic-anhydrase inhibitors
Chemmedchem
d-aspartate receptor
Drug Design
fluorescent ligands
Geldenhuys W J
Govender T
Joubert J
Journal Article or Conference Abstract Publication
Kruger H G
Malan S F
monoamine-oxidase-b
Neuroprotection
nitric-oxide
Oliver D W
parkinsons-disease
Pharmacology & Pharmacy
sigma-receptors
Van der Schyf C J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-1
Volume
26
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Importance Of Polycystin 1 (pc1) In Endothelial Mitochondrial Bioenergetics
Publisher
An entity responsible for making the resource available
Faseb Journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Creator
An entity primarily responsible for making the resource
Jones T J; Pung Y F; Adapala R K; Burke J R; Thodeti C K; Chilian W M
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Adapala R K
Biochemistry & Molecular Biology
Burke J R
Cell Biology
Chilian W M
Faseb Journal
Jones T J
Journal Article or Conference Abstract Publication
Life Sciences & Biomedicine - Other
Pung Y F
Thodeti C K
Topics
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4293/108680812x13427982376185" target="_blank" rel="noreferrer noopener">http://doi.org/10.4293/108680812x13427982376185</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
218-228
Issue
2
Volume
16
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Robotic Surgical Skills: Acquisition, Maintenance, And Degradation
Publisher
An entity responsible for making the resource available
Jsls-Journal of the Society of Laparoendoscopic Surgeons
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
cancer; Degradation; learning-curve; operative mortality; radical prostatectomy; Robotic surgical skills; surgeon; Surgery; Training; volume
Creator
An entity primarily responsible for making the resource
Jenison E L; Gil K M; Lendvay T S; Guy M S
Description
An account of the resource
Background and Objectives: The degradation in robotic skills that occurs during periods of robotic surgical inactivity in newly trained surgeons was measured. The role of animate training in robotic skill was also assessed. Methods: Robotically naive resident and attending surgeons underwent training with the da Vinci (R) robot on needle passage (DN), rocking ring transfer peg board (RPB), and running suture pod tasks (SP). Errors were established to convert actual time to adjusted time. Participants were deemed "proficient" once their adjusted times were within 80% of those set by experienced surgeons through repeated trials. Participants did not use the robot except for repeating the tasks once at 4, 8, and 12 weeks (tests). Participants then underwent animate training and completed a final test within 7 days. Results: Twenty-five attending and 29 resident surgeons enrolled; 3 withdrew. There were significant increases in time to complete each of the tasks, and in errors, by 4 weeks (Adjusted times: DN: 122.9 +/- 2.2 to 204.2 +/- 11.7, t=6.9, P<.001; RPB: 262.4 +/- 2.5 to 364.7 +/- 8.0, t=12.4, P<.001; SP: 91.4 +/- 1:4 to 169.9 +/- 6.8, t=11.3, P<.001). Times decreased following animate training, but not to levels observed after proficiency training for the RPB and SP modules. Conclusions: Robotic surgical skills degrade significantly within 4 weeks of inactivity in newly trained surgeons. Animate training may provide different skills than those acquired in the dry lab.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.4293/108680812x13427982376185" target="_blank" rel="noreferrer noopener">10.4293/108680812x13427982376185</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Cancer
degradation
Gil K M
Guy M S
Jenison E L
Journal Article or Conference Abstract Publication
Jsls-Journal of the Society of Laparoendoscopic Surgeons
learning-curve
Lendvay T S
operative mortality
radical prostatectomy
Robotic surgical skills
surgeon
Surgery
Training
volume
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3122/jabfm.2012.03.080138" target="_blank" rel="noreferrer noopener">http://doi.org/10.3122/jabfm.2012.03.080138</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
300-307
Issue
3
Volume
25
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pain And Depression In A Cohort Of Underserved, Community-dwelling Primary Care Patients
Publisher
An entity responsible for making the resource available
Journal of the American Board of Family Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-05
Subject
The topic of the resource
anxiety; association; Community Medicine; comorbidity; depression; diagnostic-tests; disorders; General & Internal Medicine; Headache; life; Medically Underserved Area; Mental Health; methodology; operating characteristic curves; Pain; physical symptoms; Population Register; prevalence
Creator
An entity primarily responsible for making the resource
Janosky J E; South-Paul J E; Lin C J
Description
An account of the resource
Purpose: Almost 17% of the US population exhibits a major depressive disorder in their lifetimes. Prevalence data show that whites experience depression earlier than African Americans, and women have a higher prevalence than men. Less is known regarding depression among underserved minority populations. The goal of our study was to examine the relationship of depression and associated self-reported conditions in participants enrolled in a community-based research registry, a substantial number of whom were underrepresented minorities. Methods: This study used a research registry of community members who had expressed interest in participating in health education projects conducted by the Center for Primary Care Community-Based Research. The patients received care at 10 family health centers. Participants were surveyed regarding family history of depression/anxiety and associated symptoms. Descriptive analyses, univariate analyses, and logistic regressions were used. Results: The population (N = 2421) included women (72.2%), African Americans (54.9%), and reported good or very good general health (68.9%). Comorbid pain was found, with headache as the predominant complaint. Compared with nonwhites, whites had a significantly higher prevalence of current depression (26.3% vs. 23.8%; P = .01), current anxiety (25.5% vs. 16.6%), and current headache (14.2% vs. 11.2%). Whites also had a higher prevalence of a family history of depression (38.4% vs. 32.1%) and anxiety (8.9% vs. 7.7%) and of taking depression (22.4% vs. 14.8%) and anxiety (15.8% vs. 7.8%) medications. However, nonwhites had a higher prevalence of leg pain (18.8% vs. 14.9%) but a lower prevalence of headache (11.2% vs. 14.2%). Conclusions: Pain was common in patients with comorbid behavioral conditions. Headache was more common in whites, whereas leg pain was more common in nonwhites. Physicians should screen for depression and anxiety in patients with headache and other pain symptoms. (J Am Board Fam Med 2012;25:300-307.)
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3122/jabfm.2012.03.080138" target="_blank" rel="noreferrer noopener">10.3122/jabfm.2012.03.080138</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Anxiety
association
Community Medicine
Comorbidity
Depression
diagnostic-tests
disorders
General & Internal Medicine
Headache
Janosky J E
Journal Article or Conference Abstract Publication
Journal of the American Board of Family Medicine
life
Lin C J
Medically Underserved Area
Mental Health
methodology
operating characteristic curves
Pain
physical symptoms
Population Register
Prevalence
South-Paul J E
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/ACM.0b013e31824d4b7c" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/ACM.0b013e31824d4b7c</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
560-566
Issue
5
Volume
87
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Dublin Core
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Title
A name given to the resource
The Unintended Consequences Of Clarity: Reviewing The Actions Of The Liaison Committee On Medical Education Before And After The Reformatting Of Accreditation Standards
Publisher
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Academic Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-05
Subject
The topic of the resource
Education & Educational Research; Health Care Sciences & Services
Creator
An entity primarily responsible for making the resource
Hunt D; Migdal M; Eaglen R; Barzansky B; Sabalis R
Description
An account of the resource
Purpose To determine the frequency of severe action decisions made by the Liaison Committee on Medical Education (LCME) in two time periods and to speculate about contributing factors for any change. Method Two study periods were reviewed. Study Period 1 (1996-2000) was before a 2002 reformatting of the standards; Study Period 2 (2004-2009) was after that reformatting. The frequency of severe action decisions and patterns of noncompliance leading to those decisions in both periods were analyzed. Results There were more severe action decisions during Study Period 2 than Study Period 1, with a notable increase in the number of recommendations for probation. Study Period 1 had substantially more noncompliance with standards within the Institutional Setting and Educational Resource categories, whereas Study Period 2 had substantially more noncompliance within the Educational Program and Medical Student categories. Conclusions The 2002 reformatting of the standards enhanced the clarity of each standard and connected previously existing annotations to their standards. As a result of the reformatting, all documents and communications to schools were directly tied to specific standards. This has allowed the LCME to more easily identify areas of chronic noncompliance and to improve survey team training. The shift in patterns of standards out of compliance in the more recent time period is consistent with the effect of the reformatting. There may be other contributing factors for the increase in severe action decisions, but it is clear that the reformatting of standards has improved the LCME's ability to monitor medical education programs.
Identifier
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<a href="http://doi.org/10.1097/ACM.0b013e31824d4b7c" target="_blank" rel="noreferrer noopener">10.1097/ACM.0b013e31824d4b7c</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Academic Medicine
Barzansky B
Eaglen R
Education & Educational Research
Health Care Sciences & Services
Hunt D
Journal Article or Conference Abstract Publication
Migdal M
Sabalis R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1037/a0027584" target="_blank" rel="noreferrer noopener">http://doi.org/10.1037/a0027584</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
734-746
Issue
4
Volume
26
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Dublin Core
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Title
A name given to the resource
Application Of The Stressor Vulnerability Model To Understanding Posttraumatic Stress Disorder (ptsd) And Alcohol-related Problems In An Undergraduate Population
Publisher
An entity responsible for making the resource available
Psychology of Addictive Behaviors
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
alcohol use disorder; differential role; events; exposed college-students; gender differences; identification test; physical abuse; posttraumatic stress disorder (PTSD); problem drinking; Psychology; refusal self-efficacy; social support; stressor; Substance Abuse; substance use; traumatic; vulnerability model
Creator
An entity primarily responsible for making the resource
Hruska B; Delahanty D L
Description
An account of the resource
Research examining the comorbidity of posttraumatic stress disorder (PTSD) and alcohol-use disorder (AUD) suggests that individuals experiencing PTSD symptoms (PTSS) often drink alcohol as a means to self-medicate their trauma symptoms; however, little attention has been given to moderating variables that may make this association more likely. The stressor vulnerability model proposes that being male, relying on maladaptive forms of coping, and holding positive alcohol-outcome expectancies predispose individuals to engage in alcohol use when experiencing psychological distress. In the current study, sex, avoidance coping (AVC), tension-reduction expectancies (TRE), and emotional-relief drinking-refusal self-efficacy. (ERDRSE) were examined as moderators of the relationship between PTSS and alcohol-related problems in a sample of 144 undergraduates. Results indicated that males reporting high levels of TRE exhibited a stronger positive relationship between PTSS and alcohol-related problems than was present for males reporting low levels of TRE and for females reporting either high or low levels of TRE. In addition, a significant positive relationship between PTSS and alcohol-related problems was observed for individuals reporting high levels of TRE and low levels of ERDRSE, but not for individuals reporting high levels of TRE and high levels of ERDRSE, low TRE-low ERDRSE, or low TRE-high ERDRSE. Assessment of these vulnerability factors in traumatized youth and young adults may serve as a useful means of identifying individuals at risk for the development of alcohol-related problems.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1037/a0027584" target="_blank" rel="noreferrer noopener">10.1037/a0027584</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
alcohol use disorder
Delahanty D L
differential role
events
exposed college-students
gender differences
Hruska B
identification test
Journal Article or Conference Abstract Publication
physical abuse
posttraumatic stress disorder (PTSD)
problem drinking
Psychology
Psychology of Addictive Behaviors
refusal self-efficacy
Social Support
stressor
Substance Abuse
Substance use
traumatic
vulnerability model
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
E263-E263
Volume
52
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Morphology And Histology Of Avian Quill Knobs: The Fine Structure Of Remigial Feather Attachments
Publisher
An entity responsible for making the resource available
Integrative and Comparative Biology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Zoology
Creator
An entity primarily responsible for making the resource
Hieronymus T L; Simons E L R
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Hieronymus T L
Integrative and comparative biology
Journal Article or Conference Abstract Publication
Simons E L R
Zoology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
110-111
Volume
32
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Bony Attachments Of Flight Feathers In Neornithine Birds: Anatomy, Histology And Functional Variation
Publisher
An entity responsible for making the resource available
Journal of Vertebrate Paleontology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012
Subject
The topic of the resource
Paleontology
Creator
An entity primarily responsible for making the resource
Hieronymus T L; Simons E L
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Hieronymus T L
Journal Article or Conference Abstract Publication
Journal of Vertebrate Paleontology
Paleontology
Simons E L
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s10029-012-0941-2" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s10029-012-0941-2</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
677-687
Issue
6
Volume
16
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Title
A name given to the resource
Bone Marrow-derived Mesenchymal Stromal Cells And Platelet-rich Plasma On A Collagen Matrix To Improve Fascial Healing
Publisher
An entity responsible for making the resource available
Hernia
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
chronic wounds; closure; growth-factor; Hernia; in-vitro; incisional hernia; Mesenchymal; PRP (platelet-rich plasma); rat; repair; Stem; stem-cells; Stromal; Surgery; suture; tissue
Creator
An entity primarily responsible for making the resource
Heffner J J; Holmes J W; Ferrari J P; Krontiris-Litowitz J; Marie H; Fagan D L; Perko J C; Dorion H A
Description
An account of the resource
To demonstrate improved healing of a midline laparotomy after application of mesenchymal stromal cells and platelet-rich plasma on a collagen matrix and introduce a potential cellular-based therapy for the prevention of incisional hernia formation. Up to 10 % of laparotomies are complicated by postoperative incisional hernias. Despite continuous improvements in surgical technique and technology, hernia rates have remained constant. Cell-based therapies focused on augmentation of the body's natural healing properties could reduce hernia formation. Midline laparotomies were performed on 42 Lewis rats. Three groups were studied: (1) primary repair only, (2) primary repair with CollaTape (TM) (CoTa) overlay and platelet-rich plasma (PRP), and (3) primary repair with CoTa overlay and PRP and bone marrow-derived mesenchymal stromal cells (BM-MSCs). Abdominal wall fascia was recovered at 4 and 8 weeks in each group. Biomechanical testing and histological evaluation was performed. At 4 weeks, there was a twofold increase in tensile strength between groups 1 and 2 and a fourfold increase between groups 1 and 3 (p < 0.001). Group 3 had a 320 % increase in total energy absorption at 4 weeks compared to group 1 and a 142 % increase at 8 weeks (p < 0.001). Vascularization and collagen abundance were significantly increased in group 3 at both time points. The addition of BM-MSCs, PRP, and CoTa led to a marked improvement in abdominal wall strength and energy absorption. Histologic evaluation confirmed increased vascularity and collagen abundance consistent with the biomechanical findings. Application of this therapy may ultimately reduce incisional hernia formation.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s10029-012-0941-2" target="_blank" rel="noreferrer noopener">10.1007/s10029-012-0941-2</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
chronic wounds
closure
Dorion H A
Fagan D L
Ferrari J P
growth-factor
Heffner J J
Hernia
Holmes J W
in-vitro
incisional hernia
Journal Article or Conference Abstract Publication
Krontiris-Litowitz J
Marie H
Mesenchymal
Perko J C
PRP (platelet-rich plasma)
rat
repair
Stem
stem-cells
Stromal
Surgery
suture
tissue
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1186/1475-2840-11-150" target="_blank" rel="noreferrer noopener">http://doi.org/10.1186/1475-2840-11-150</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
11-11
Volume
11
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Detecting Dna Synthesis Of Neointimal Formation After Catheter Balloon Injury In Gk And In Wistar Rats: Using 5-ethynyl-2 '-deoxyuridine
Publisher
An entity responsible for making the resource available
Cardiovascular Diabetology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
alkynes; arterial injury; balloon injury; Cardiovascular System & Cardiology; carotid-artery; Catheter; cell-cycle progression; click chemistry; diabetes-mellitus; diabetes-mellitus; DNA synthesis; EdU; eluting stents; Endocrinology & Metabolism; in-vitro; mammalian target; Neointimal formation; PCNA; proliferation; terminal
Creator
An entity primarily responsible for making the resource
Guo J S; Li D Y; Bai S R; Xu T D; Zhou Z M; Zhang Y B
Description
An account of the resource
Background: Neointimal formation plays an important role in the pathogenesis of coronary restenosis after percutaneous coronary intervention (PCI), especially in patients with diabetes mellitus. Recently, some studies have shown that 5-ethynyl-2'-deoxyuridine (EdU) incorporation can serve as a novel alternative to the 5-bromo-2'-deoxyuridine (BrdU) antibody detection method for detection of DNA synthesis in regenerating avian cochlea, chick embryo and the adult nervous system. However, few studies have been performed to assess the suitability of EdU for detecting DNA synthesis in vascular neointima. Methods: The carotid artery balloon injury model was established in Goto-Kakizaki (GK) and Wistar rats. A Cell-Light (TM) EdU Kit was used to detect EdU-labeled cell nuclei of common carotid arteries at day 7 after catheter balloon injury. Different methods of injecting EdU were tested. The protein levels of proliferating cell nuclear antigen (PCNA) and p-Akt (Ser473), as well as the mRNA levels of PCNA were evaluated by Western blotting and quantitative real-time PCR (qRT-PCR), respectively. Immunohistochemical staining was also employed to visualize PCNA-positive cells. Results: At day 7 after catheter balloon injury, far more EdU-positive and PCNA-positive cells were observed in GK rats. When comparing groups that received different EdU doses, it was found that the percentage of EdU-positive cells at a dose of 100 mg/kg body weight was than at doses of 25 mg/kg and 50 mg/kg. The number of positive cells was significantly higher in the repeated injection group compared to the single injection group. Further, after balloon injury DNA synthesis in GK rats was more notable than in Wistar rats. Neointimal formation in GK rats was more obvious than in Wistar rats. The protein levels of PCNA and p-Akt (Ser473) and the mRNA levels of PCNA were increased in injured rats as compared to uninjured rats, and were significantly higher in GK rats than in Wistar rats. Conclusion: By intraperitoneal injections of EdU at a dose of 100 mg/kg three times, EdU incorporation can detect carotid arterial DNA synthesis caused by neointimal formation in GK rats and Wistar rats at day 7 after balloon injury by the EdU click reaction quickly and effectively. Moreover, more obvious DNA synthesis in the vascular neointima could be observed in GK rats than in Wistar rats.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1186/1475-2840-11-150" target="_blank" rel="noreferrer noopener">10.1186/1475-2840-11-150</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
alkynes
arterial injury
Bai S R
balloon injury
Cardiovascular Diabetology
Cardiovascular System & Cardiology
carotid-artery
Catheter
cell-cycle progression
click chemistry
diabetes-mellitus
DNA synthesis
EdU
eluting stents
Endocrinology & Metabolism
Guo J S
in-vitro
Journal Article or Conference Abstract Publication
Li D Y
mammalian target
Neointimal formation
PCNA
proliferation
terminal
Xu T D
Zhang Y B
Zhou Z M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1245/s10434-012-2578-x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1245/s10434-012-2578-x</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
3139-3143
Issue
10
Volume
19
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Title
A name given to the resource
Evaluation Of Appropriate Short-term Mammographic Surveillance In Patients Who Undergo Breast-conserving Surgery (bcs)
Publisher
An entity responsible for making the resource available
Annals of Surgical Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
cancer; carcinoma; conservative surgery; follow-up; irradiation; local recurrence; lumpectomy; Oncology; radiation-therapy; radiotherapy; stage-i; Surgery
Creator
An entity primarily responsible for making the resource
Gunia S R; Merrigan T L; Poulton T B; Mamounas E P
Description
An account of the resource
Mammography is an important surveillance tool for detecting ipsilateral breast tumor recurrence (IBTR) after BCS. Although IBTR is rare in the first 2 years, various organizations have established protocols for postoperative mammographic surveillance. Currently there is no consensus on the optimal interval for imaging evaluation of patients following BCS. We conducted a retrospective review of patients who underwent BCS at Aultman Hospital between 1/06 and 12/08. To be included in the study, patients had to be diagnosed with invasive primary breast carcinoma or ductal carcinoma in situ (DCIS), treated with BCS (with or without postoperative breast radiation), and have had at least one postoperative surveillance mammogram at our Breast Care Center. Our mammographic surveillance protocol for patients undergoing BCS consists of ipsilateral mammograms (affected side) around 6 and 18 months and bilateral mammograms around 12 and 24 months. All mammograms that were Breast Imaging-Reporting and Data System (BIRADS) 0 or 4 were reviewed by a single radiologist (T.B.P.). A total of 375 patients constituted the core group for this study. Each interval mammographic screening (6- and 18-month mammograms) resulted in additional imaging in 3-4 % of patients. There was a very low yield for identifying IBTR: 1/266 (0.4 %) for the 5-10-month postoperative mammogram and 1/286 (0.3 %) for the 16-21-month postoperative mammogram. Based on our data and the low expected yield of IBTR in the first 2 years, annual mammographic surveillance appears adequate following BCS and interval ipsilateral mammograms at 6 and 18 months do not provide additional clinical benefit.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1245/s10434-012-2578-x" target="_blank" rel="noreferrer noopener">10.1245/s10434-012-2578-x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Annals of surgical oncology
Cancer
Carcinoma
conservative surgery
Follow-up
Gunia S R
irradiation
Journal Article or Conference Abstract Publication
local recurrence
Lumpectomy
Mamounas E P
Merrigan T L
oncology
Poulton T B
radiation-therapy
Radiotherapy
stage-i
Surgery
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0051646" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0051646</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
18-18
Issue
12
Volume
7
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Dublin Core
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Title
A name given to the resource
Processing Of Communication Calls In Guinea Pig Auditory Cortex
Publisher
An entity responsible for making the resource available
Plos One
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-12
Subject
The topic of the resource
Acoustic noise; Action potentials; Anesthesia; Auditory cortex; Brain research; Broadband; Communication; conspecific; Auditory cortex; Cortex (temporal); cortical discrimination; Councils; functional specialization; Guinea pigs; Localization; Macaque; Medical research; Monkeys; neural representation; Neurobiology; neurons; Neurosciences; Ohio; purr call; rhesus-monkey; Saimiri; Science & Technology - Other Topics; Sciences: Comprehensive Works; single neurons; social vocalizations; Sound; species-specific vocalizations; squirrel-monkeys; Stimuli; United Kingdom--UK; Urethane; Vocalization; vocalizations
Creator
An entity primarily responsible for making the resource
Grimsley J M S; Shanbhag S J; Palmer A R; Wallace M N
Description
An account of the resource
Vocal communication is an important aspect of guinea pig behaviour and a large contributor to their acoustic environment. We postulated that some cortical areas have distinctive roles in processing conspecific calls. In order to test this hypothesis we presented exemplars from all ten of their main adult vocalizations to urethane anesthetised animals while recording from each of the eight areas of the auditory cortex. We demonstrate that the primary area (AI) and three adjacent auditory belt areas contain many units that give isomorphic responses to vocalizations. These are the ventrorostral belt (VRB), the transitional belt area (T) that is ventral to AI and the small area (area S) that is rostral to AI. Area VRB has a denser representation of cells that are better at discriminating among calls by using either a rate code or a temporal code than any other area. Furthermore, 10% of VRB cells responded to communication calls but did not respond to stimuli such as clicks, broadband noise or pure tones. Area S has a sparse distribution of call responsive cells that showed excellent temporal locking, 31% of which selectively responded to a single call. AI responded well to all vocalizations and was much more responsive to vocalizations than the adjacent dorsocaudal core area. Areas VRB, AI and S contained units with the highest levels of mutual information about call stimuli. Area T also responded well to some calls but seems to be specialized for low sound levels. The two dorsal belt areas are comparatively unresponsive to vocalizations and contain little information about the calls. AI projects to areas S, VRB and T, so there may be both rostral and ventral pathways for processing vocalizations in the guinea pig.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1371/journal.pone.0051646" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0051646</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Acoustic noise
Action Potentials
Anesthesia
auditory cortex
Brain research
Broadband
Communication
conspecific
Cortex (temporal)
cortical discrimination
Councils
functional specialization
Grimsley J M S
Guinea Pigs
Journal Article or Conference Abstract Publication
localization
Macaque
MEDICAL research
monkeys
neural representation
Neurobiology
Neurons
Neurosciences
Ohio
Palmer A R
PloS one
purr call
rhesus-monkey
saimiri
Science & Technology - Other Topics
Sciences: Comprehensive Works
Shanbhag S J
single neurons
social vocalizations
Sound
species-specific vocalizations
squirrel-monkeys
Stimuli
United Kingdom--UK
Urethane
Vocalization
vocalizations
Wallace M N
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2174/156800912803987896" target="_blank" rel="noreferrer noopener">http://doi.org/10.2174/156800912803987896</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1191-1232
Issue
9
Volume
12
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Dietary Phytochemicals In The Chemoprevention And Treatment Of Hepatocellular Carcinoma: In Vivo Evidence, Molecular Targets, And Clinical Relevance
Publisher
An entity responsible for making the resource available
Current Cancer Drug Targets
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-11
Subject
The topic of the resource
acid phenethyl ester; altered hepatic foci; black tea; carcinoma; Chemoprevention; dietary; diethylnitrosamine-induced hepatocarcinogenesis; hepatocarcinogenesis; hepatocellular; implanted; liver cancer; liver preneoplastic foci; model; multiorgan carcinogenesis model; nitrosodiethylamine-induced; nude-mice; Oncology; phenobarbital-induced hepatocarcinogenesis; phytochemicals; polyphenols; resistant hepatocyte; treatment
Creator
An entity primarily responsible for making the resource
Bishayee A; Thoppil R J; Waghray A; Kruse J A; Novotny N A; Darvesh A S
Description
An account of the resource
Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, the majority of detected cases of liver cancer have been found in the developing nations of Asia and Africa; however, its occurrence has significantly increased in the United States. HCC occurs due to several etiologies, such as alcoholism, dietary carcinogens, iron overload, viral hepatitis, as well as several hepatic chronic diseases. In view of the limited treatment options, such as surgery and transplantation, a critical need exists to examine alternative approaches. The use of phytochemicals obtained from dietary sources provides a novel and fascinating preventive and therapeutic approach against HCC. Dietary phytochemicals possess potent antioxidant and anti-inflammatory properties which are extremely critical to combat the significant oxidative stress and inflammation implicated in liver cancer. An impressive number of phytochemicals have shown considerable promise as candidates for the prevention and treatment of HCC. In this article, we systematically review the in vivo pre-clinical evidence documenting the chemopreventive and therapeutic potential of several important dietary phytochemicals in HCC. This review critically examines the molecular mechanisms of the pharmacological effects of the aforementioned animal studies. Clinical and epidemiological studies are also highlighted in this review. Emerging issues such as bioavailability, dose optimization, targeted drug delivery, role of botanical extracts and synergy are also discussed. Finally, current challenges, limitations, future directions, innovative concepts and novel hypotheses for the use of dietary phytochemicals in the chemoprevention and amelioration of human HCC are presented.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.2174/156800912803987896" target="_blank" rel="noreferrer noopener">10.2174/156800912803987896</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
acid phenethyl ester
altered hepatic foci
Bishayee A
black tea
Carcinoma
Chemoprevention
Current cancer drug targets
Darvesh A S
Department of Pharmaceutical Sciences
Dietary
diethylnitrosamine-induced hepatocarcinogenesis
Hepatocarcinogenesis
Hepatocellular
Implanted
Journal Article or Conference Abstract Publication
Kruse J A
Liver cancer
liver preneoplastic foci
model
multiorgan carcinogenesis model
NEOMED College of Pharmacy
nitrosodiethylamine-induced
Novotny N A
nude-mice
oncology
phenobarbital-induced hepatocarcinogenesis
phytochemicals
Polyphenols
resistant hepatocyte
Thoppil R J
Treatment
Waghray A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1021/ml200196p" target="_blank" rel="noreferrer noopener">http://doi.org/10.1021/ml200196p</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
39-42
Issue
1
Volume
3
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Molecular Insights Into Human Monoamine Oxidase B Inhibition By The Glitazone Antidiabetes Drugs
Publisher
An entity responsible for making the resource available
Acs Medicinal Chemistry Letters
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-01
Subject
The topic of the resource
Antidiabetes drug; Chemistry; drug design; gamma agonist pioglitazone; high-level expression; lsd1; monoamine oxidase; mouse model; neurodegeneration; neuroprotection; parkinsons-disease; parkinsons-disease; Pharmacology & Pharmacy; pichia-pastoris; pioglitazone; rosiglitazone
Creator
An entity primarily responsible for making the resource
Binda C; Aldeco M; Geldenhuys W J; Tortorici M; Mattevi A; Edmondson D E
Description
An account of the resource
The widely employed antidiabetic drug pioglitazone (Actos) is shown to be a specific and reversible inhibitor of human monoamine oxidase B (MAO B). The crystal structure of the enzyme-inhibitor complex shows that the R-enantiomer is bound with the thiazolidinedione ring near the flavin. The molecule occupies both substrate and entrance cavities of the active site, establishing noncovalent interactions with the surrounding amino acids. These binding properties differentiate pioglitazone from the clinically used MAO inhibitors, which act through covalent inhibition mechanisms and do not exhibit a high degree of MAO A versus B selectivity. Rosiglitazone (Avandia) and troglitazone, other members of the glitazone class, are less selective in that they are weaker inhibitors of both MAO A and MAO B. These results suggest that pioglitazone may have utility as a "repurposed" neuroprotectant drug in retarding the progression of disease in Parkinson's patients. They also provide new insights for the development of reversible isoenzyme-specific MAO inhibitors.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1021/ml200196p" target="_blank" rel="noreferrer noopener">10.1021/ml200196p</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Acs Medicinal Chemistry Letters
Aldeco M
Antidiabetes drug
Binda C
Chemistry
Drug Design
Edmondson D E
gamma agonist pioglitazone
Geldenhuys W J
high-level expression
Journal Article or Conference Abstract Publication
lsd1
Mattevi A
monoamine oxidase
Mouse model
Neurodegeneration
Neuroprotection
parkinsons-disease
Pharmacology & Pharmacy
pichia-pastoris
pioglitazone
Rosiglitazone
Tortorici M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jacc.2012.02.082" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jacc.2012.02.082</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
951-956
Issue
11
Volume
60
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Obstructive Coronary Atherosclerosis And Ischemic Heart Disease: An Elusive Link!
Publisher
An entity responsible for making the resource available
Journal of the American College of Cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-09
Subject
The topic of the resource
angina; artery-disease; atherosclerosis; Cardiovascular System & Cardiology; clinical presentation; follow-up; fractional flow reserve; Ischemic heart disease; medical therapy; multifactorial; myocardial-infarction; prognostic value; reactive protein-levels; revascularization; risk-factors; stable
Creator
An entity primarily responsible for making the resource
Marzilli M; Merz C N B; Boden W E; Bonow R O; Capozza P G; Chilian W M; DeMaria A N; Guarini G; Huqi A; Morrone D; Patel M R; Weintraub W S
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jacc.2012.02.082" target="_blank" rel="noreferrer noopener">10.1016/j.jacc.2012.02.082</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Angina
artery-disease
Atherosclerosis
Boden W E
Bonow R O
Capozza P G
Cardiovascular System & Cardiology
Chilian W M
clinical presentation
DeMaria A N
Department of Internal Medicine
Follow-up
fractional flow reserve
Guarini G
Huqi A
Ischemic heart disease
Journal of the American College of Cardiology
Marzilli M
medical therapy
Merz C N B
Morrone D
multifactorial
myocardial-infarction
NEOMED College of Medicine
Patel M R
prognostic value
reactive protein-levels
revascularization
risk-factors
stable
Weintraub W S
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.5301/jva.5000039" target="_blank" rel="noreferrer noopener">http://doi.org/10.5301/jva.5000039</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
231-238
Issue
2
Volume
13
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Risk Factors For Upper Extremity Venous Thrombosis Associated With Peripherally Inserted Central Venous Catheters
Publisher
An entity responsible for making the resource available
Journal of Vascular Access
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Cardiovascular System & Cardiology; chronic kidney-disease; deep-vein thrombosis; pH; PICC lines; Prophylaxis; retrospective analysis; risk-factors; thromboembolism; thrombophlebitis; trauma; Upper extremity venous thrombosis
Creator
An entity primarily responsible for making the resource
Marnejon T; Angelo D; Abu Abdou A; Gemmel D
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.5301/jva.5000039" target="_blank" rel="noreferrer noopener">10.5301/jva.5000039</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Abu Abdou A
Angelo D
Cardiovascular System & Cardiology
chronic kidney-disease
deep-vein thrombosis
Gemmel D
Journal of Vascular Access
Marnejon T
ph
PICC lines
prophylaxis
retrospective analysis
risk-factors
thromboembolism
thrombophlebitis
trauma
Upper extremity venous thrombosis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.det.2011.08.005" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.det.2011.08.005</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
107-+
Issue
1
Volume
30
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Us Skin Disease Assessment: Ulcer And Wound Care
Publisher
An entity responsible for making the resource available
Dermatologic Clinics
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-01
Subject
The topic of the resource
burden; Chronic ulcers; costs; Dermatology; diabetic foot ulcers; Diabetic neuropathic; foot ulcers; guidelines; management; multicenter; Pressure ulcers; prevalence; prevention; retrospective cohort; venous leg ulcer; Venous leg ulcers
Creator
An entity primarily responsible for making the resource
Markova A; Mostow E N
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.det.2011.08.005" target="_blank" rel="noreferrer noopener">10.1016/j.det.2011.08.005</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
burden
Chronic ulcers
costs
Dermatologic clinics
Dermatology
diabetic foot ulcers
Diabetic neuropathic
foot ulcers
guidelines
Management
Markova A
Mostow E N
multicenter
Pressure ulcers
Prevalence
Prevention
retrospective cohort
venous leg ulcer
Venous leg ulcers
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/jts.21731" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/jts.21731</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
543-550
Issue
5
Volume
25
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Pharmacological Secondary Prevention Of Ptsd In Youth: Challenges And Opportunities For Advancement
Publisher
An entity responsible for making the resource available
Journal of Traumatic Stress
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
children; conditioned fear; cortisol; memory; morphine; pediatric injury patients; posttraumatic-stress-disorder; propranolol; Psychiatry; Psychology; stress; symptoms; traumatic
Creator
An entity primarily responsible for making the resource
Maccani M A; Delahanty D L; Nugent N R; Berkowitz S J
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/jts.21731" target="_blank" rel="noreferrer noopener">10.1002/jts.21731</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Berkowitz S J
Children
conditioned fear
Cortisol
Delahanty D L
Journal of Traumatic Stress
Maccani M A
Memory
MORPHINE
Nugent N R
pediatric injury patients
posttraumatic-stress-disorder
Propranolol
Psychiatry
Psychology
Stress
Symptoms
traumatic
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1136/heartjnl-2012-302920a.154" target="_blank" rel="noreferrer noopener">http://doi.org/10.1136/heartjnl-2012-302920a.154</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
E62-E63
Volume
98
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Interference With Akt Signaling In Dyslipidemia Diminishes Myocardial Infarction And Promotes Survival By Inhibiting Oxidative Stress
Publisher
An entity responsible for making the resource available
Heart
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
Cardiovascular System & Cardiology
Creator
An entity primarily responsible for making the resource
Ma L N; Kerr B A; West X Z; Malinin N L; Weber M E; Ding L; Somanath P R; Penn M S; Podrez E A; Byzova T V
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1136/heartjnl-2012-302920a.154" target="_blank" rel="noreferrer noopener">10.1136/heartjnl-2012-302920a.154</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Byzova T V
Cardiovascular System & Cardiology
Ding L
heart
Kerr B A
Ma L N
Malinin N L
Penn M S
Podrez E A
Somanath P R
Weber M E
West X Z
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-1
Volume
26
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Knockout Of Type Vi Collagen Improves Cardiac Function And Remodeling Following Myocardial Infarction
Publisher
An entity responsible for making the resource available
Faseb Journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Creator
An entity primarily responsible for making the resource
Luther D J; Thodeti C K; Weihrauch D; Patel H H; Niesman I R; Bonaldo P; Chilian W M; Meszaros J G
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Biochemistry & Molecular Biology
Bonaldo P
Cell Biology
Chilian W M
Faseb Journal
Life Sciences & Biomedicine - Other
Luther D J
Meszaros J G
Niesman I R
Patel H H
Thodeti C K
Topics
Weihrauch D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ygyno.2011.11.002" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ygyno.2011.11.002</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
426-430
Issue
3
Volume
124
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Endometrial Cancer Survivors' Assessment Of The Benefits Of Exercise
Publisher
An entity responsible for making the resource available
Gynecologic Oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-03
Subject
The topic of the resource
adherence; breast; Cancer survivors; exercise; Health beliefs; intervention; maintenance; Obesity; Obstetrics & Gynecology; Oncology; outcome expectations; physical-activity; quality-of-life; risk; self-efficacy; women
Creator
An entity primarily responsible for making the resource
Lukowski J; Gil K M; Jenison E; Hopkins M; Basen-Engquist K
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.ygyno.2011.11.002" target="_blank" rel="noreferrer noopener">10.1016/j.ygyno.2011.11.002</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
adherence
Basen-Engquist K
breast
Cancer Survivors
Exercise
Gil K M
Gynecologic oncology
Health beliefs
Hopkins M
Intervention
Jenison E
Lukowski J
maintenance
Obesity
Obstetrics & Gynecology
oncology
outcome expectations
physical-activity
quality-of-life
Risk
self-efficacy
Women
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1553-2712.2011.01248.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1553-2712.2011.01248.x</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
68-69
Issue
1
Volume
19
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
They Always Will Be With Us
Publisher
An entity responsible for making the resource available
Academic Emergency Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-01
Subject
The topic of the resource
Emergency Medicine; public-health research
Creator
An entity primarily responsible for making the resource
Gerson L W; Hauswald M
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1553-2712.2011.01248.x" target="_blank" rel="noreferrer noopener">10.1111/j.1553-2712.2011.01248.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Academic Emergency Medicine
Emergency Medicine
Gerson L W
Hauswald M
public-health research
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S137-S137
Volume
60
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Acute Heart Failure In An Elder With Multimorbidities: The "nonlinear Patient Trap."
Publisher
An entity responsible for making the resource available
Journal of the American Geriatrics Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-04
Subject
The topic of the resource
Geriatrics & Gerontology
Creator
An entity primarily responsible for making the resource
Gao B; Gottlieb S H
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Gao B
Geriatrics & Gerontology
Gottlieb S H
Journal of the American Geriatrics Society
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
E289-E289
Issue
10
Volume
32
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Title
A name given to the resource
Student College Of Clinical Pharmacy Provides Education About Medications And Fall Risk For Akron Area Agency On Aging Care Managers
Publisher
An entity responsible for making the resource available
Pharmacotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-10
Subject
The topic of the resource
Pharmacology & Pharmacy
Creator
An entity primarily responsible for making the resource
Fredrickson M E; Smith A; Gallegos P; Soric M; Fosnight S
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Department of Pharmaceutical Sciences
Department of Pharmacy Practice
Fosnight S
Fredrickson M E
Gallegos P
NEOMED College of Pharmacy
Pharmacology & Pharmacy
Pharmacotherapy
Smith A
Soric M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.3109/14653249.2012.684380" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/14653249.2012.684380</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
983-993
Issue
8
Volume
14
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Cardiac Pressure Overload Initiates A Systemic Stem Cell Response
Publisher
An entity responsible for making the resource available
Cytotherapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-09
Subject
The topic of the resource
& Experimental Medicine; acute myocardial-infarction; Biotechnology & Applied Microbiology; bone marrow; bone marrow; cardiac stem cells; cardiomyocytes; Cell Biology; endogenous stem cells; endothelial; endothelial progenitor cells; heart; Hematology; hypertrophy; identification; murine; peripheral-blood; progenitor cells; regeneration; Research; spleen; SSEA-1; transaortic constriction; transplantation
Creator
An entity primarily responsible for making the resource
Finan A; Kiedrowski M; Turturice B A; Sopko N A; Penn M S
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.3109/14653249.2012.684380" target="_blank" rel="noreferrer noopener">10.3109/14653249.2012.684380</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
& Experimental Medicine
2012
acute myocardial-infarction
Biotechnology & Applied Microbiology
bone marrow
cardiac stem cells
cardiomyocytes
Cell Biology
Cytotherapy
endogenous stem cells
Endothelial
endothelial progenitor cells
Finan A
heart
Hematology
Hypertrophy
identification
Kiedrowski M
murine
Penn M S
peripheral-blood
progenitor cells
Regeneration
Research
Sopko N A
spleen
SSEA-1
transaortic constriction
Transplantation
Turturice B A