1
40
407
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/jocn.14531" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/jocn.14531</a>
Pages
3572–3582
Issue
19
Volume
27
Dublin Core
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Title
A name given to the resource
A broader understanding of care managers' attitudes of advance care planning: A concurrent nested design.
Publisher
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Journal of clinical nursing
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-10
Subject
The topic of the resource
*Attitude of Health Personnel; *Health Knowledge; Adult; Advance Care Planning; Advance Care Planning/*standards; Attitudes; Case Managers; Chi Square Test; community health; Concurrent Prospective Studies; Convenience Sample; decision-making; Discussion; end of life; Female; Focus Groups; Funding Source; Health Services Accessibility/standards; Human; Humans; Male; Middle Age; Middle Aged; Midwestern United States; Multicenter Studies; Multimethod Studies; Nurse Attitudes; nurses; Practice; qualitative; Qualitative Research; quantitative; Questionnaires; Surveys; Surveys and Questionnaires; Thematic Analysis
Creator
An entity primarily responsible for making the resource
Aultman Julie; Baughman Kristin R; Ludwick Ruth
Description
An account of the resource
AIMS AND OBJECTIVES: To examine barriers of advance care planning (ACP) experienced by care managers (CMs) through a mixed methods approach. A concurrent nested design was used to acquire a deeper understanding of ACP and to identify nuances between quantitative and qualitative data. BACKGROUND: Past quantitative studies on providers have identified barriers related to time, culture, knowledge, responsibility and availability of legal documents. These barriers, and accompanying attitudes and feelings, have been taken at face value without rich qualitative data to identify under what conditions and to what extent a barrier impacts care. DESIGN: A two-part multisite, mixed methods study was conducted using surveys and focus groups. METHODS: Surveys were completed by 458 CMs at 10 Area Agencies on Aging and 62 participated in one of eight focus groups. Data were analysed using a concurrent nested design with individual data analysis and a merged data approach. RESULTS: There were three main distinctions between the quantitative and qualitative data. First, while CMs reported on the survey that ACP was not too time consuming, focus group data revealed that time was an issue especially related to competing priorities. Second on the survey 60% of the CMS reported they had enough knowledge, but qualitative data revealed about more nuances. Last, the reported comfort levels in the quantitative data were less overt in the qualitative date where additional feelings and attitudes were revealed, for example, frustration with families, preferences for more physician involvement. CONCLUSIONS: Care managers reported their attitudes about ACP, clarified through a rigorous mixed methods analysis. Care managers can successfully lead ACP discussions, but require further education, resources and team-based guidance. RELEVANCE TO CLINICAL PRACTICE: Advance care planning is essential for reducing emotional, social and financial burdens associated with healthcare decision-making, and CMs can positively impact ACP discussions when appropriately supported by the clinical community. The many nuances in the ACP process that we found illustrate the need for ongoing discussions, education and research on this important topic.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/jocn.14531" target="_blank" rel="noreferrer noopener">10.1111/jocn.14531</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Attitude of Health Personnel
*Health Knowledge
2018
Adult
advance care planning
Advance Care Planning/*standards
Attitudes
Aultman Julie
Baughman Kristin R
Case Managers
Chi Square Test
College of Graduate Studies
Community health
Concurrent Prospective Studies
Convenience Sample
Decision-making
Department of Family & Community Medicine
Discussion
end of life
Female
Focus Groups
Funding Source
Health Services Accessibility/standards
Human
Humans
Journal of clinical nursing
Ludwick Ruth
Male
Middle Age
Middle Aged
Midwestern United States
Multicenter Studies
Multimethod Studies
NEOMED College of Graduate Studies
NEOMED College of Medicine
Nurse Attitudes
nurses
Practice
Qualitative
Qualitative Research
quantitative
Questionnaires
Surveys
Surveys and Questionnaires
Thematic Analysis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.00154.2018" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.00154.2018</a>
Pages
H1262–H1263
Issue
6
Volume
314
Dublin Core
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Title
A name given to the resource
A chicken and egg conundrum: coronary microvascular dysfunction and heart failure with preserved ejection fraction.
Publisher
An entity responsible for making the resource available
American journal of physiology. Heart and circulatory physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-06
Creator
An entity primarily responsible for making the resource
Ohanyan Vahagn; Sisakian Hamayak; Peketi Punita; Parikh Ankur; Chilian William
Identifier
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<a href="http://doi.org/10.1152/ajpheart.00154.2018" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.00154.2018</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
American journal of physiology. Heart and circulatory physiology
Chilian William
Department of Integrative Medical Sciences
NEOMED College of Medicine
Ohanyan Vahagn
Parikh Ankur
Peketi Punita
Sisakian Hamayak
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
374-375
Volume
33
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Title
A name given to the resource
A Comparison Between Osteoactivin and Bone Morphogenetic Protein-2 in Rat Spinal Fusion Model
Publisher
An entity responsible for making the resource available
Journal of Bone and Mineral Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-11
Subject
The topic of the resource
Endocrinology & Metabolism
Creator
An entity primarily responsible for making the resource
Robinson J; McDermott S; Budge K; Hussein N; Jaber F; Azem O; Desanto M; Raslan A; Saleh M; Inkrott B; Safadi F F
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n/a
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The file format, physical medium, or dimensions of the resource
Journal Article
2018
Azem O
Budge K
Desanto M
Endocrinology & Metabolism
Hussein N
Inkrott B
Jaber F
Journal Article
Journal of Bone and Mineral Research
McDermott S
Raslan A
Robinson J
Safadi F F
Saleh M
-
Text
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URL Address
<a href="http://doi.org/10.1176/appi.ps.201700341" target="_blank" rel="noreferrer noopener">http://doi.org/10.1176/appi.ps.201700341</a>
Pages
1001–1006
Issue
9
Volume
69
Dublin Core
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Title
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A Comparison of Participants in Two Community-Based Programs: Assisted Outpatient Treatment and a Mental Health Court.
Publisher
An entity responsible for making the resource available
Psychiatric services (Washington, D.C.)
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
The topic of the resource
Assisted Outpatient Treatment; mental health courts; Outpatient commitment
Creator
An entity primarily responsible for making the resource
Bonfine Natalie; Ritter Christian; Teller Jennifer L S; Munetz Mark R
Description
An account of the resource
OBJECTIVE: Mental health courts and assisted outpatient treatment (AOT) are tools to help people with serious mental illness engage in treatment and avoid or reduce institutionalization. As both programs become increasingly prevalent, questions remain about whether people with severe mental illness who receive AOT have the same characteristics, histories, and service needs as those who participate in mental health courts. If there are differences, each program may require assessments and interventions tailored to the specific characteristics and needs of participants. METHODS: This study examined administrative criminal justice and mental health services data for 261 people with serious mental illness who participated in AOT, a mental health court, or both over seven years. RESULTS: Three percent of the sample participated in both programs. Compared with participants in mental health court, participants in AOT were older, less likely to have an alcohol use disorder, and more likely to have a schizophrenia spectrum disorder than a bipolar disorder. The participants' histories of crisis mental health service utilization, hospitalization, and incarceration prior to program entry varied significantly by program. CONCLUSIONS: The findings suggest that there are differences among individuals with serious mental illness who are served by AOT and mental health court programs. AOT participants had greater engagement with mental health services, and a significant portion of AOT participants also had a prior criminal history that placed them at risk of future justice involvement. Program administrators need to recognize and address the clinical and criminogenic needs that place individuals at risk of becoming hospitalized and incarcerated.
Identifier
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<a href="http://doi.org/10.1176/appi.ps.201700341" target="_blank" rel="noreferrer noopener">10.1176/appi.ps.201700341</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Assisted Outpatient Treatment
Bonfine Natalie
College of Graduate Studies
Department of Family & Community Medicine
Department of Psychiatry
mental health courts
Munetz Mark R
NEOMED College of Graduate Studies
NEOMED College of Medicine
Outpatient commitment
Psychiatric services (Washington, D.C.)
Ritter Christian
Teller Jennifer L S
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ar.23991" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ar.23991</a>
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1002/ar.24045" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1002/ar.24045</a>
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Title
A name given to the resource
A Comparison of the Cortical Structure of the Bowhead Whale (Balaena mysticetus), a Basal Mysticete, with Other Cetaceans.
Publisher
An entity responsible for making the resource available
Anatomical record (Hoboken, N.J. : 2007)
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-10
Subject
The topic of the resource
baleen whale; cytoarchitecture; humpback whale; minke whale; sperm whale
Creator
An entity primarily responsible for making the resource
Raghanti Mary Ann; Wicinski Bridget; Meierovich Rachel; Warda Tahia; Dickstein Dara L; Reidenberg Joy S; Tang Cheuk Y; George John C; Hans Thewissen J G M; Butti Camilla; Hof Patrick R
Description
An account of the resource
Few studies exist of the bowhead whale brain and virtually nothing is known about its cortical cytoarchitecture or how it compares to other cetaceans. Bowhead whales are one of the least encephalized cetaceans and occupy a basal phylogenetic position among mysticetes. Therefore, the bowhead whale is an important specimen for understanding the evolutionary specializations of cetacean brains. Here, we present an overview of the structure and cytoarchitecture of the bowhead whale cerebral cortex gleaned from Nissl-stained sections and magnetic resonance imaging (MRI) in comparison with other mysticetes and odontocetes. In general, the cytoarchitecture of cetacean cortex is consistent in displaying a thin cortex, a thick, prominent layer I, and absence of a granular layer IV. Cell density, composition, and width of layers III, V, and VI vary among cortical regions, and cetacean cortex is cell-sparse relative to that of terrestrial mammals. Notably, all regions of the bowhead cortex possess high numbers of von Economo neurons and fork neurons, with the highest numbers observed at the apex of gyri. The bowhead whale is also distinctive in having a significantly reduced hippocampus that occupies a space below the corpus callosum within the lateral ventricle. Consistent with other balaenids, bowhead whales possess what appears to be a blunted temporal lobe, which is in contrast to the expansive temporal lobes that characterize most odontocetes. The present report demonstrates that many morphological and cytoarchitectural characteristics are conserved among cetaceans, while other features, such as a reduced temporal lobe, may characterize balaenids among mysticetes. Anat Rec, 2018. (c) 2018 Wiley Periodicals, Inc.
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<a href="http://doi.org/10.1002/ar.23991" target="_blank" rel="noreferrer noopener">10.1002/ar.23991</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Anatomical record (Hoboken, N.J. : 2007)
Baleen whale
Butti Camilla
cytoarchitecture
Department of Anatomy & Neurobiology
Dickstein Dara L
George John C
Hans Thewissen J G M
Hof Patrick R
humpback whale
Meierovich Rachel
minke whale
NEOMED College of Medicine
Raghanti Mary Ann
Reidenberg Joy S
sperm whale
Tang Cheuk Y
Warda Tahia
Wicinski Bridget
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
71-75
Issue
1
Volume
18
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Title
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A description of inter-professional ethics education in a United States college of pharmacy
Publisher
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Pharmacy Education
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018
Subject
The topic of the resource
Education & Educational Research; Ethics Education; Ethics Training; Inter-Professional Education
Creator
An entity primarily responsible for making the resource
Aultman J M
Description
An account of the resource
Introduction: An inter-professional ethics curriculum should address core ethics concepts and principles, and challenge students to work in inter-professional teams to resolve dilemmas modelled after those encountered in the health professions. Description: An inter-professional ethics curriculum at a United States (U.S.) college of pharmacy has been developed and refined since 2005 and provides comprehensive ethics education to pharmacy students, while exposing medical and pharmacy students to the ethical issues and dilemmas that are both shared and unique to each health profession. Evaluation: Students have exceeded basic competencies in ethics education without failing performance measures at this U.S. college of pharmacy. The inter-professional ethics curriculum receives positive student evaluations; however, students see ethics education as secondary, rather than complementary, to basic science and clinical curricula. Future plans: A commitment to a longitudinal, inter-professional ethics curriculum is needed to enforce ethics content and values during students' practicum experiences in pharmacy and industry settings.
Identifier
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n/a
Format
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Journal Article or Conference Abstract Publication
2018
Aultman J M
Department of Family & Community Medicine
Education & Educational Research
Ethics Education
Ethics Training
Inter-Professional Education
Journal Article or Conference Abstract Publication
NEOMED College of Medicine
pharmacy education
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1080/14787210.2018.1503054" target="_blank" rel="noreferrer noopener">http://doi.org/10.1080/14787210.2018.1503054</a>
Pages
591–593
Issue
8
Volume
16
Dublin Core
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Title
A name given to the resource
A formidable foe: carbapenem-resistant Acinetobacter baumannii and emerging nonantibiotic therapies.
Publisher
An entity responsible for making the resource available
Expert review of anti-infective therapy
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-08
Subject
The topic of the resource
*Carbapenem-resistant Acinetobacter baumannii; *decolonization; *hospital-acquired infections; *therapies; *vaccination; Acinetobacter baumannii/drug effects/*isolation & purification; Acinetobacter Infections – Microbiology; Acinetobacter Infections – Therapy; Acinetobacter Infections/microbiology/*therapy; Animals; Anti-Bacterial Agents/pharmacology; Antibiotics – Pharmacodynamics; Bacterial; Carbapenems – Pharmacodynamics; Carbapenems/pharmacology; Drug Resistance; Gram-Negative Aerobic Bacteria; Gram-Negative Aerobic Bacteria – Drug Effects; Humans; Microbial; Microbial Culture and Sensitivity Tests; Microbial Sensitivity Tests
Creator
An entity primarily responsible for making the resource
Watkins Richard R
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1080/14787210.2018.1503054" target="_blank" rel="noreferrer noopener">10.1080/14787210.2018.1503054</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Carbapenem-resistant Acinetobacter baumannii
*decolonization
*hospital-acquired infections
*therapies
*vaccination
2018
Acinetobacter baumannii/drug effects/*isolation & purification
Acinetobacter Infections – Microbiology
Acinetobacter Infections – Therapy
Acinetobacter Infections/microbiology/*therapy
Animals
Anti-Bacterial Agents/pharmacology
Antibiotics – Pharmacodynamics
Bacterial
Carbapenems – Pharmacodynamics
Carbapenems/pharmacology
Department of Internal Medicine
Drug Resistance
Expert review of anti-infective therapy
Gram-Negative Aerobic Bacteria
Gram-Negative Aerobic Bacteria – Drug Effects
Humans
Microbial
Microbial Culture and Sensitivity Tests
Microbial Sensitivity Tests
NEOMED College of Medicine
Watkins Richard R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
2-2
Volume
197
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Title
A name given to the resource
A Leaky Situation: Gadolinium Contrast Induced Neurotoxicity from Intrathecal Contrast
Publisher
An entity responsible for making the resource available
American Journal of Respiratory and Critical Care Medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018
Subject
The topic of the resource
General & Internal Medicine; Respiratory System
Creator
An entity primarily responsible for making the resource
Sese D; Blaha T; Khurana R; Wachsman A; Al-Ali F; Murray T; Cucci A R
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Al-Ali F
American journal of respiratory and critical care medicine
Blaha T
Cucci A R
Department of Internal Medicine
General & Internal Medicine
Journal Article
Khurana R
Murray T
NEOMED College of Medicine
Respiratory System
Sese D
Wachsman A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S131-S131
Volume
26
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Title
A name given to the resource
A Neofunctionalized Gene Zcchc5 Is Expressed In Cartilage And Its Downregulation Inhibits Col2a1 Expression And Enhances The Expression Of Mmp-13 In Chondrocytes
Publisher
An entity responsible for making the resource available
Osteoarthritis and Cartilage
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
Orthopedics; Rheumatology
Creator
An entity primarily responsible for making the resource
Khan N M; Haqqi T M
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2018
Haqqi T M
Journal Article or Conference Abstract Publication
Khan N M
Orthopedics
Osteoarthritis and cartilage
Rheumatology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1073/pnas.1719666115" target="_blank" rel="noreferrer noopener">http://doi.org/10.1073/pnas.1719666115</a>
Pages
E1108–E1116
Issue
6
Volume
115
Dublin Core
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Title
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A neurochemical hypothesis for the origin of hominids.
Publisher
An entity responsible for making the resource available
Proceedings of the National Academy of Sciences of the United States of America
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-02
Subject
The topic of the resource
*Ardipithecus; *basal ganglia; *Biological Evolution; *dopamine; *hominin; *Neurochemistry; *neurotransmitter; *Selection; *Social Behavior; Altruism; Animals; Corpus Striatum/*physiology; Dogs; Genetic; Humans; Personality; Primates; Social Conformity
Creator
An entity primarily responsible for making the resource
Raghanti Mary Ann; Edler Melissa K; Stephenson Alexa R; Munger Emily L; Jacobs Bob; Hof Patrick R; Sherwood Chet C; Holloway Ralph L; Lovejoy C Owen
Description
An account of the resource
It has always been difficult to account for the evolution of certain human characters such as language, empathy, and altruism via individual reproductive success. However, the striatum, a subcortical region originally thought to be exclusively motor, is now known to contribute to social behaviors and "personality styles" that may link such complexities with natural selection. We here report that the human striatum exhibits a unique neurochemical profile that differs dramatically from those of other primates. The human signature of elevated striatal dopamine, serotonin, and neuropeptide Y, coupled with lowered acetylcholine, systematically favors externally driven behavior and greatly amplifies sensitivity to social cues that promote social conformity, empathy, and altruism. We propose that selection induced an initial form of this profile in early hominids, which increased their affiliative behavior, and that this shift either preceded or accompanied the adoption of bipedality and elimination of the sectorial canine. We further hypothesize that these changes were critical for increased individual fitness and promoted the adoption of social monogamy, which progressively increased cooperation as well as a dependence on tradition-based cultural transmission. These eventually facilitated the acquisition of language by elevating the reproductive advantage afforded those most sensitive to social cues.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1073/pnas.1719666115" target="_blank" rel="noreferrer noopener">10.1073/pnas.1719666115</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Ardipithecus
*basal ganglia
*Biological Evolution
*dopamine
*hominin
*Neurochemistry
*neurotransmitter
*Selection
*Social Behavior
2018
Altruism
Animals
Corpus Striatum/*physiology
Dogs
Edler Melissa K
Genetic
Hof Patrick R
Holloway Ralph L
Humans
Jacobs Bob
Lovejoy C Owen
Munger Emily L
Personality
Primates
Proceedings of the National Academy of Sciences of the United States of America
Raghanti Mary Ann
Sherwood Chet C
Social Conformity
Stephenson Alexa R
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
2-2
Volume
70
Search for Full-text
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Title
A name given to the resource
A Novel Role of ZCCHC6 in the Regulation of MMP13 in Experimental Osteoarthritis in Mice
Publisher
An entity responsible for making the resource available
Arthritis & Rheumatology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
The topic of the resource
Rheumatology
Creator
An entity primarily responsible for making the resource
Ansari M Y; Ahmad N; Haqqi T M
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2018
Ahmad N
Ansari M Y
Arthritis & Rheumatology
Haqqi T M
Journal Article or Conference Abstract Publication
Rheumatology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.plefa.2017.01.003" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.plefa.2017.01.003</a>
Pages
153–159
Volume
136
Dublin Core
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Title
A name given to the resource
A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity.
Publisher
An entity responsible for making the resource available
Prostaglandins, leukotrienes, and essential fatty acids
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
The topic of the resource
Arachidonic acid; Eicosanoids; Mass spectrometry; Niacin; Plasma; Prostanoids; Schizophrenia; Ultra performance liquid chromatography; UPLC-MS/MS
Creator
An entity primarily responsible for making the resource
Miller Tricia M; Poloyac Samuel M; Anderson Kacey B; Waddell Brooke L; Messamore Erik; Yao Jeffrey K
Description
An account of the resource
A rapid and sensitive method using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed to simultaneously quantify hydroxyeicosatetraenoic (HETE), dihydroxyeicosatrienoic (DiHETrE), epoxyeicosatrienoic acid (EET), and prostaglandin metabolites of arachidonic acid in human plasma. Sample preparation consisted of solid phase extraction with Oasis HLB (30mg) cartridges for all metabolites. Separation of HETEs, EETs, and DiHETrEs was achieved on an Acquity UPLC BEH C18, 1.7microm (100x2.1mm) reversed-phase column (Waters Corp, Millford, MA) with negative electrospray ionization mass spectrometric detection. A second injection of the same extracted sample allowed for separation and assessment of prostaglandin metabolites under optimized UPLC-MS/MS conditions. Additionally, the endogenous levels of these metabolites in five different matrices were determined in order to select the optimal matrix for assay development. Human serum albumin was shown to have the least amount of endogenous metabolites, a recovery efficiency of 79-100% and a matrix effect of 71 - 100%. Linear calibration curves ranging from 0.416 to 66.67ng/ml were validated. Inter-assay and intra-assay variance was less than 15% at most concentrations. This method was successfully applied to quantify metabolite levels in plasma samples of healthy control subjects receiving niacin administration to evaluate the association between niacin administration and eicosanoid plasma level response.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.plefa.2017.01.003" target="_blank" rel="noreferrer noopener">10.1016/j.plefa.2017.01.003</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Anderson Kacey B
Arachidonic Acid
Eicosanoids
Mass spectrometry
Messamore Erik
Miller Tricia M
Niacin
Plasma
Poloyac Samuel M
Prostaglandins, leukotrienes, and essential fatty acids
Prostanoids
Schizophrenia
Ultra performance liquid chromatography
UPLC-MS/MS
Waddell Brooke L
Yao Jeffrey K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1097/COC.0000000000000355" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/COC.0000000000000355</a>
Pages
178–190
Issue
2
Volume
41
Dublin Core
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Title
A name given to the resource
A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice.
Publisher
An entity responsible for making the resource available
American journal of clinical oncology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-02
Subject
The topic of the resource
*Bandages; Adult; Aged; Breast Neoplasms/*complications/pathology/*surgery; Cohort Studies; Combined Modality Therapy; Drainage/methods; Female; Humans; Lymphedema/etiology/physiopathology/*therapy; Massage/methods; Mastectomy/*adverse effects/methods; Middle Aged; Prognosis; Quality of Life; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Severity of Illness Index; Survivors; Treatment Outcome
Creator
An entity primarily responsible for making the resource
Smile Timothy D; Tendulkar Rahul; Schwarz Graham; Arthur Douglas; Grobmyer Stephen; Valente Stephanie; Vicini Frank; Shah Chirag
Description
An account of the resource
OBJECTIVES: Breast cancer-related lymphedema (BCRL) represents a major complication of breast cancer treatment, impacting the quality of life for breast cancer survivors that develop it. The purpose of this review is to evaluate the literature surrounding BCRL treatment modalities to guide clinicians regarding risk-stratified treatment options. METHODS: A review of studies over a 10-year period (January 2006 to February 2016) was performed. Noninvasive strategies evaluated included compression therapy, manual lymphatic drainage, and complex decongestive therapy (CDT). Invasive modalities evaluated included liposuction and lymphatic bypass/lymph node transfer (LNT). Our search yielded 149 initial results with 45 studies included. RESULTS: A number of prospective studies have found that CDT is associated with volume reduction in the affected limb as well as improved quality of life, particularly in patients with early stage BCRL. With regards to invasive treatment options, data support that lymphatic bypass and LNT are associated with symptomatic and physiologic improvements, particularly in patients with more advanced BCRL. In addition, a small number of studies suggest that liposuction may be an efficacious and safe treatment for moderate to severe BCRL. CONCLUSIONS: CDT is an effective treatment modality for early stage BCRL. For more advanced BCRL, LNT has demonstrated efficacy. Further study is required with respect to comparing BCRL treatment modalities.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1097/COC.0000000000000355" target="_blank" rel="noreferrer noopener">10.1097/COC.0000000000000355</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Bandages
2018
Adult
Aged
American journal of clinical oncology
Arthur Douglas
Breast Neoplasms/*complications/pathology/*surgery
Cohort Studies
Combined Modality Therapy
Drainage/methods
Female
Grobmyer Stephen
Humans
Lymphedema/etiology/physiopathology/*therapy
Massage/methods
Mastectomy/*adverse effects/methods
Middle Aged
Prognosis
Quality of Life
Randomized Controlled Trials as Topic
Retrospective Studies
Risk Assessment
Schwarz Graham
Severity of Illness Index
Shah Chirag
Smile Timothy D
Survivors
Tendulkar Rahul
Treatment Outcome
Valente Stephanie
Vicini Frank
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jaad.2018.10.016" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jaad.2018.10.016</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A Technique to Provide Enhanced Visualization For Suture Cutting In Dermatologic Surgery.
Publisher
An entity responsible for making the resource available
Journal of the American Academy of Dermatology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-10
Subject
The topic of the resource
dermatologic surgery; skin; suture; technique
Creator
An entity primarily responsible for making the resource
Neill Brett C; Tarantino Isadore S; Stevens Jason; Hocker Thomas L H
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jaad.2018.10.016" target="_blank" rel="noreferrer noopener">10.1016/j.jaad.2018.10.016</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
dermatologic surgery
Hocker Thomas L H
Journal of the American Academy of Dermatology
Neill Brett C
Skin
Stevens Jason
suture
Tarantino Isadore S
technique
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.neuroimage.2018.08.013" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.neuroimage.2018.08.013</a>
Pages
300–313
Volume
183
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
A three-dimensional digital neurological atlas of the mustached bat (Pteronotus parnellii).
Publisher
An entity responsible for making the resource available
NeuroImage
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-12
Subject
The topic of the resource
*Atlases as Topic; Animals; Auditory Cortex/anatomy & histology/diagnostic imaging; Brain Stem/anatomy & histology/diagnostic imaging; Brain/*anatomy & histology/diagnostic imaging; Chiroptera/*anatomy & histology; Diffusion Tensor Imaging/methods; Imaging; Magnetic Resonance Imaging/*methods; Male; Skull/anatomy & histology/diagnostic imaging; Three-Dimensional/*methods; Tomography; X-Ray Computed/*methods
Creator
An entity primarily responsible for making the resource
Washington Stuart D; Hamaide Julie; Jeurissen Ben; van Steenkiste Gwendolyn; Huysmans Toon; Sijbers Jan; Deleye Steven; Kanwal Jagmeet S; De Groof Geert; Liang Sayuan; Van Audekerke Johan; Wenstrup Jeffrey J; Van der Linden Annemie; Radtke-Schuller Susanne; Verhoye Marleen
Description
An account of the resource
Substantial knowledge of auditory processing within mammalian nervous systems emerged from neurophysiological studies of the mustached bat (Pteronotus parnellii). This highly social and vocal species retrieves precise information about the velocity and range of its targets through echolocation. Such high acoustic processing demands were likely the evolutionary pressures driving the over-development at peripheral (cochlea), metencephalic (cochlear nucleus), mesencephalic (inferior colliculus), diencephalic (medial geniculate body of the thalamus), and telencephalic (auditory cortex) auditory processing levels in this species. Auditory researchers stand to benefit from a three dimensional brain atlas of this species, due to its considerable contribution to auditory neuroscience. Our MRI-based atlas was generated from 2 sets of image data of an ex-vivo male mustached bat's brain: a detailed 3D-T2-weighted-RARE scan [(59x63 x 85) mum(3)] and track density images based on super resolution diffusion tensor images [(78) mum(3)] reconstructed from a set of low resolution diffusion weighted images using Super-Resolution-Reconstruction (SRR). By surface-rendering these delineations and extrapolating from cortical landmarks and data from previous studies, we generated overlays that estimate the locations of classic functional subregions within mustached bat auditory cortex. This atlas is freely available from our website and can simplify future electrophysiological, microinjection, and neuroimaging studies in this and related species.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.neuroimage.2018.08.013" target="_blank" rel="noreferrer noopener">10.1016/j.neuroimage.2018.08.013</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Atlases as Topic
2018
Animals
Auditory Cortex/anatomy & histology/diagnostic imaging
Brain Stem/anatomy & histology/diagnostic imaging
Brain/*anatomy & histology/diagnostic imaging
Chiroptera/*anatomy & histology
College of Anatomy & Neurobiology
De Groof Geert
Deleye Steven
Department of Anatomy & Neurobiology
Diffusion Tensor Imaging/methods
Hamaide Julie
Huysmans Toon
Imaging
Jeurissen Ben
Kanwal Jagmeet S
Liang Sayuan
Magnetic Resonance Imaging/*methods
Male
NEOMED College of Medicine
NeuroImage
Radtke-Schuller Susanne
Sijbers Jan
Skull/anatomy & histology/diagnostic imaging
Three-Dimensional/*methods
Tomography
Van Audekerke Johan
Van der Linden Annemie
van Steenkiste Gwendolyn
Verhoye Marleen
Washington Stuart D
Wenstrup Jeffrey J
X-Ray Computed/*methods
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ajpa.23686" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ajpa.23686</a>
Pages
569–584
Issue
3
Volume
167
Dublin Core
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Title
A name given to the resource
A user's guide for the quantitative analysis of substrate characteristics and locomotor kinematics in free-ranging primates.
Publisher
An entity responsible for making the resource available
American journal of physical anthropology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-11
Subject
The topic of the resource
branch diameter; compliance; gait; orientation; quadrupedalism
Creator
An entity primarily responsible for making the resource
Dunham Noah T; McNamara Allison; Shapiro Liza; Hieronymus Tobin; Young Jesse W
Description
An account of the resource
OBJECTIVES: Laboratory studies have yielded important insights into primate locomotor mechanics. Nevertheless, laboratory studies fail to capture the range of ecological and structural variation encountered by free-ranging primates. We present techniques for collecting kinematic data on wild primates using consumer grade high-speed cameras and demonstrate novel methods for quantifying metric variation in arboreal substrates. MATERIALS AND METHODS: These methods were developed and applied to our research examining platyrrhine substrate use and locomotion at the Tiputini Biodiversity Station, Ecuador. Modified GoPro cameras equipped with varifocal zoom lenses provided high-resolution footage (1080 p.; 120 fps) suitable for digitizing gait events. We tested two methods for remotely measuring branch diameter: the parallel laser method and the distance meter photogrammetric method. A forestry-grade laser rangefinder was used to quantify substrate angle and a force gauge was used to measure substrate compliance. We also introduce GaitKeeper, a graphical user interface for MATLAB, designed for coding quadrupedal gait. RESULTS: Parallel laser and distance meter methods provided accurate estimations of substrate diameter (percent error: 3.1-4.5%). The laser rangefinder yielded accurate estimations of substrate orientation (mean error = 2.5 degrees ). Compliance values varied tremendously among substrates but were largely explained by substrate diameter, substrate length, and distance of measurement point from trunk. On average, larger primates used relatively small substrates and traveled higher in the canopy. DISCUSSION: Ultimately, these methods will help researchers identify more precisely how primate gait kinematics respond to the complexity of arboreal habitats, furthering our understanding of the adaptive context in which primate quadrupedalism evolved.
Identifier
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<a href="http://doi.org/10.1002/ajpa.23686" target="_blank" rel="noreferrer noopener">10.1002/ajpa.23686</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
American journal of physical anthropology
branch diameter
Compliance
Department of Anatomy & Neurobiology
Dunham Noah T
Gait
Hieronymus Tobin
McNamara Allison
NEOMED College of Medicine
Orientation
quadrupedalism
Shapiro Liza
Young Jesse W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1113/JP275735" target="_blank" rel="noreferrer noopener">http://doi.org/10.1113/JP275735</a>
Pages
1981–1997
Issue
10
Volume
596
Dublin Core
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Title
A name given to the resource
Activity-dependent synaptic integration and modulation of bilateral excitatory inputs in an auditory coincidence detection circuit.
Publisher
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The Journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-05
Subject
The topic of the resource
EPSC; mGluR; neuromodulation; synaptic integration
Creator
An entity primarily responsible for making the resource
Lu Yong; Liu Yu-Wei; Curry Rebecca J
Description
An account of the resource
KEY POINTS: Binaural excitatory inputs to coincidence detection neurons in nucleus laminaris (NL) play essential roles in interaural time difference coding for sound localization. Here, we show that the two excitatory inputs are physiologically nearly completely segregated. Synaptic integration shows linear summation of EPSPs, ensuring high efficiency of coincidence detection of the bilateral excitatory inputs. We further show that the two excitatory inputs to single NL neurons are symmetrical in synaptic strength, kinetics and short-term plasticity. Modulation of the EPSCs by metabotropic glutamate receptors (mGluRs) is identical between the two excitatory inputs, maintaining balanced bilateral excitation under neuromodulatory conditions. Unilateral hearing deprivation reduces synaptic excitation and paradoxically strengthens mGluR modulation of EPSCs, suggesting activity-dependent anti-homeostatic regulation, a novel synaptic plasticity in response to sensory manipulations. ABSTRACT: Neurons in the avian nucleus laminaris (NL) receive bilateral excitatory inputs from the cochlear nucleus magnocellularis, via morphologically symmetrical dorsal (ipsilateral) and ventral (contralateral) dendrites. Using in vitro whole-cell patch recordings in chicken brainstem slices, we investigated synaptic integration and modulation of the bilateral inputs to NL under normal and hearing deprivation conditions. We found that the two excitatory inputs onto single NL neurons were nearly completely segregated, and integration of the two inputs was linear for EPSPs. The two inputs had similar synaptic strength, kinetics and short-term plasticity. EPSCs in low but not middle and high frequency neurons were suppressed by activation of group I and II metabotropic glutamate receptors (mGluR I and II), with similar modulatory strength between the ipsilateral and contralateral inputs. Unilateral hearing deprivation by cochlea removal reduced the excitatory transmission on the deprived dendritic domain of NL. Interestingly, EPSCs evoked at the deprived domain were modulated more strongly by mGluR II than at the counterpart domain that received intact input in low frequency neurons, suggesting anti-homeostatic regulation. This was supported by a stronger expression of mGluR II protein on the deprived neuropils of NL. Under mGluR II modulation, EPSCs on the deprived input show transient synaptic facilitation, forming a striking contrast with normal hearing conditions under which pure synaptic depression is observed. These results demonstrate physiological symmetry and thus balanced bilateral excitatory inputs to NL neurons. The activity-dependent anti-homeostatic plasticity of mGluR modulation constitutes a novel mechanism regulating synaptic transmission in response to sensory input manipulations.
Identifier
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<a href="http://doi.org/10.1113/JP275735" target="_blank" rel="noreferrer noopener">10.1113/JP275735</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Curry Rebecca J
Department of Anatomy & Neurobiology
EPSC
Liu Yu-Wei
Lu Yong
mGluR
NEOMED College of Medicine
neuromodulation
synaptic integration
The Journal of physiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ajem.2018.03.073" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ajem.2018.03.073</a>
Pages
1521.e1–1521.e2
Issue
8
Volume
36
Dublin Core
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Title
A name given to the resource
Acute aortic occlusion in a patient without risk factors.
Publisher
An entity responsible for making the resource available
The American journal of emergency medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-08
Subject
The topic of the resource
Acute aortic occlusion; Arterial Occlusive Diseases; Fall
Creator
An entity primarily responsible for making the resource
Stoneham Trina; Simon Erin L
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.ajem.2018.03.073" target="_blank" rel="noreferrer noopener">10.1016/j.ajem.2018.03.073</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Acute aortic occlusion
Arterial Occlusive Diseases
Department of Emergency Medicine
Fall
NEOMED College of Medicine
Simon Erin L
Stoneham Trina
The American journal of emergency medicine
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Acute Eclampsia
Publisher
An entity responsible for making the resource available
StatPearls
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-01
Creator
An entity primarily responsible for making the resource
Gill Prabhcharan; Van Hook MD James W
Description
An account of the resource
Eclampsia is a uniquely pregnancy-related disorder that manifests as new onset of generalized tonic colonic seizures. It typically occurs after 20 weeks of concluded gestation, although it may occur sooner with plural gestations or molar pregnancies, and may additionally occur in the 6-week postpartum window. It represents the severe end of the preeclampsia spectrum. Preeclampsia spectrum includes symptoms of the central nervous system (CNS), for example, severe headaches or vision changes, and may involve hepatic abnormalities (such as elevated liver transaminases with right upper quadrant/epigastric discomfort), elevated blood pressures, and also may include thrombocytopenia, renal abnormalities, and pulmonary edema. In developed countries, resultant maternal mortality may be as high as 1.8%, and in the developing countries, it may be as high as 14%.[1]
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Gill Prabhcharan
StatPearls
Van Hook MD James W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/2382120518803111" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/2382120518803111</a>
Pages
2382120518803111–2382120518803111
Volume
5
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Adaptation of the Roseman 6-Point Mastery Learning Model to the College of Medicine Program.
Publisher
An entity responsible for making the resource available
Journal of medical education and curricular development
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-12
Subject
The topic of the resource
medical education; Medical student curriculum; outcomes
Creator
An entity primarily responsible for making the resource
Lazerson Jack; Rosenthal Judith; Glaubensklee Carolyn; Hunt Thomas; Morgenstern Bruce; Pamidimukkala Jayabala; Penn David M; Rosenthal Ken; Sarsekeyeva Mira; Wragg Stephanie
Description
An account of the resource
Medical education has evolved over time toward a model which integrates clinical medicine with the basic sciences. More recently, medical education has put an emphasis on outcome-based education. Other areas of health care education have had a similar emphasis which can provide models to inform a new model for medical education. The Roseman University of Health Sciences has developed and implemented a model based on underlying tenets of mastery learning since 1999. The model has been implemented in pharmacy, nursing, and dental education. It was conceived as an integration of 6 key points which reinforce each other and interrelate to support learning. The model has been modified for application to medical education in support of medical education's outcome-based emphasis and to address the educational demands of the changing environment of the practice of medicine.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/2382120518803111" target="_blank" rel="noreferrer noopener">10.1177/2382120518803111</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Glaubensklee Carolyn
Hunt Thomas
Journal of medical education and curricular development
Lazerson Jack
Medical education
Medical student curriculum
Morgenstern Bruce
outcomes
Pamidimukkala Jayabala
Penn David M
Rosenthal Judith
Rosenthal Ken
Sarsekeyeva Mira
Wragg Stephanie
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.heares.2018.03.013" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.heares.2018.03.013</a>
Pages
119–135
Volume
363
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Addressing variability in the acoustic startle reflex for accurate gap detection assessment.
Publisher
An entity responsible for making the resource available
Hearing research
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-06
Subject
The topic of the resource
Acoustic startle response magnitude; Circadian rhythm; Gap-induced prepulse inhibition of the acoustic startle reflex; Prepulse facilitation; Tinnitus
Creator
An entity primarily responsible for making the resource
Longenecker Ryan J; Kristaponyte Inga; Nelson Gregg L; Young Jesse W; Galazyuk Alexander V
Description
An account of the resource
The acoustic startle reflex (ASR) is subject to substantial variability. This inherent variability consequently shapes the conclusions drawn from gap-induced prepulse inhibition of the acoustic startle reflex (GPIAS) assessments. Recent studies have cast doubt as to the efficacy of this methodology as it pertains to tinnitus assessment, partially, due to variability in and between data sets. The goal of this study was to examine the variance associated with several common data collection variables and data analyses with the aim to improve GPIAS reliability. To study this the GPIAS tests were conducted in adult male and female CBA/CaJ mice. Factors such as inter-trial interval, circadian rhythm, sex differences, and sensory adaptation were each evaluated. We then examined various data analysis factors which influence GPIAS assessment. Gap-induced facilitation, data processing options, and assessments of tinnitus were studied. We found that the startle reflex is highly variable in CBA/CaJ mice, but this can be minimized by certain data collection factors. We also found that careful consideration of temporal fluctuations of the ASR and controlling for facilitation can lead to more accurate GPIAS results. This study provides a guide for reducing variance in the GPIAS methodology - thereby improving the diagnostic power of the test.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.heares.2018.03.013" target="_blank" rel="noreferrer noopener">10.1016/j.heares.2018.03.013</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Acoustic startle response magnitude
Circadian Rhythm
Department of Anatomy & Neurobiology
Galazyuk Alexander V
Gap-induced prepulse inhibition of the acoustic startle reflex
Hearing research
Kristaponyte Inga
Longenecker Ryan J
Nelson Gregg L
NEOMED College of Medicine
Prepulse facilitation
Tinnitus
Young Jesse W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4187/respcare.06024" target="_blank" rel="noreferrer noopener">http://doi.org/10.4187/respcare.06024</a>
Pages
1111–1117
Issue
9
Volume
63
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Adherence to Endotracheal Tube Depth Guidelines and Incidence of Malposition in Infants and Children.
Publisher
An entity responsible for making the resource available
Respiratory Care
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
The topic of the resource
Female; Humans; pediatrics; Male; Ohio; Random Allocation; Incidence; Chi-Square Distribution; Child; Guideline Adherence/*statistics & numerical data; Infant; intubation; Medical Errors/*statistics & numerical data; NRP; PALS; Radiography/*statistics & numerical data; Trachea/diagnostic imaging; tracheal tube malposition; United States; Odds Ratio; Intensive Care Units; Hospitals; Guideline Adherence; Radiography; Intubation; ROC Curve; Confidence Intervals; Inpatients; Human; Chi Square Test; Descriptive Statistics; P-Value; Data Analysis Software; Practice Guidelines; Retrospective Design; Preschool; Thoracic; Intratracheal/adverse effects/standards/*statistics & numerical data; Intratracheal – Standards – United States; Pediatric – Ohio
Creator
An entity primarily responsible for making the resource
Volsko Teresa A; McNinch Neil L; Prough Donald S; Bigham Michael T
Description
An account of the resource
BACKGROUND: Adherence to guidelines for endotracheal tube (ETT) insertion depth may not be sufficient to prevent malposition or harm to the patient. To obtain an estimate of ETT malpositioning, we evaluated initial postintubation chest radiographs and hypothesized that many ETTs in multiple intubation settings would be malpositioned despite adherence to Pediatric Advanced Life Support and Neonatal Resuscitation Program guidelines. METHODS: In a random subset (randomization table) of 2,000 initial chest radiographs obtained from January 1, 2009, to May 5, 2012, we recorded height, weight, age, sex, ETT inner diameter, and cm marking at the lip from the electronic health record. Chest radiographs of poor quality and with spinal or skeletal deformities were excluded. We defined adherence to Pediatric Advanced Life Support or Neonatal Resuscitation Program guidelines as the difference between predicted and actual ETT markings at the lip as +/- 0.25, +/- 0.50, or +/- 1.0 cm for ETTs of 2.5-4, 4.5-6.0, or \textgreater6.5 mm inner diameter, respectively. We defined the proper position as the ETT tip being below the thoracic inlet (superior border of the clavicular heads) and \textgreater/=1 cm above the carina. Descriptive statistics reported demographics, guideline adherence, and malposition incidence. The chi-square test was used to assess relationships among intubation setting, malposition, and depth guideline adherence (P \textless .05, significant). RESULTS: We reviewed 507 records, 477 of which met inclusion criteria and had sufficient data for analysis. Fifty-six percent of the subjects were male, with median (interquartile range) age 15.2 (3.4-59.4) months, and 330 ETTs (69%) were malpositioned: 39 above the thoracic inlet, and 291 \textless 1 cm above the carina. Of 79 ETTS (17%) that adhered to depth guidelines, 56 (74%) were malpositioned. Three-hundred seventy-three ETTs (83%) did not meet guidelines. Two-hundred sixty-four (68%) were malpositioned. The intubation setting did not influence malposition or guideline adherence (P = .54). CONCLUSIONS: In infants and children, a high proportion of ETTs were malpositioned on the first postintubation chest radiograph, with little influence of guideline adherence.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.4187/respcare.06024" target="_blank" rel="noreferrer noopener">10.4187/respcare.06024</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Bigham Michael T
Chi Square Test
Chi-Square Distribution
Child
Confidence Intervals
Data Analysis Software
Descriptive Statistics
Female
Guideline Adherence
Guideline Adherence/*statistics & numerical data
Hospitals
Human
Humans
Incidence
Infant
Inpatients
Intensive Care Units
Intratracheal – Standards – United States
Intratracheal/adverse effects/standards/*statistics & numerical data
Intubation
Male
McNinch Neil L
Medical Errors/*statistics & numerical data
NRP
Odds Ratio
Ohio
P-Value
PALS
Pediatric – Ohio
Pediatrics
Practice Guidelines
Preschool
Prough Donald S
Radiography
Radiography/*statistics & numerical data
Random Allocation
Respiratory care
Retrospective Design
ROC Curve
Thoracic
Trachea/diagnostic imaging
tracheal tube malposition
United States
Volsko Teresa A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
31A-31A
Volume
42
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Title
A name given to the resource
ADIPOSE-SPECIFIC LIPIN-1 OVEREXPRESSION INDUCES FERROPTOSIS AND AGGRAVATES EXPERIMENTAL ALCOHOLIC STEATOHEPATITIS IN MICE
Publisher
An entity responsible for making the resource available
Alcoholism-Clinical and Experimental Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-08
Subject
The topic of the resource
Substance Abuse
Creator
An entity primarily responsible for making the resource
Zhou Z; Daniels M; Kainrad N; Bonavita G; Ye T J; You M
Identifier
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n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Alcoholism-Clinical and Experimental Research
Bonavita G
Daniels M
Department of Pharmaceutical Sciences
Journal Article
Kainrad N
NEOMED College of Pharmacy
Substance Abuse
Ye T J
You M
Zhou Z
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S329-S329
Volume
66
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Title
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Advance care planning decisions by dementia caregivers
Publisher
An entity responsible for making the resource available
Journal of the American Geriatrics Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
Geriatrics & Gerontology
Creator
An entity primarily responsible for making the resource
Shah S B; Hanson L C; Gabriel S; Lin F; Ernecoff N C
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Ernecoff N C
Gabriel S
Geriatrics & Gerontology
Hanson L C
Journal Article
Journal of the American Geriatrics Society
Lin F
Shah S B
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/2192568217720681" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/2192568217720681</a>
Pages
178–189
Issue
2
Volume
8
Dublin Core
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Title
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Adverse Events Following Cervical Disc Arthroplasty: A Systematic Review.
Publisher
An entity responsible for making the resource available
Global spine journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
adverse events; cervical disc arthroplasty; complications; industry funding; systematic review
Creator
An entity primarily responsible for making the resource
Xu Jordan C; Goel Chandni; Shriver Michael F; Tanenbaum Joseph E; Steinmetz Michael P; Benzel Edward C; Mroz Thomas E
Description
An account of the resource
Study Design: Systematic review. Objectives: Cervical arthroplasty is an increasingly popular treatment of cervical radiculopathy and myelopathy. An understanding of the potential adverse events (AEs) is important to help both clinicians and patients. We sought to provide a comprehensive systematic review of the AEs reported in all randomized controlled trials (RCTs) of cervical disc arthroplasty in an attempt to characterize the quality of reporting. Methods: We conducted a systematic review of MEDLINE and Web of Science for RCTs of cervical disc arthroplasty reporting AEs. We reported the most frequently mentioned AEs, including dysphagia/dysphonia, vascular compromise, dural injury, and infections. We recorded the presence of industry funding and scored the quality of collection methods and reporting of AEs. Results: Of the 3734 identified articles, 29 articles met full inclusion criteria. The quality of AE reporting varied significantly between studies, and a combined meta-analysis was not feasible. The 29 articles covered separate 19 RCTs. Eight studies were US Food and Drug Administration (FDA) investigational device exemption (IDE) trials. Rates were recorded for the following AEs: dysphagia/dysphonia (range = 1.3% to 27.2%), vascular compromise (range = 1.1% to 2.4%), cervical wound infection (range = 1.2% to 22.5%), and cerebrospinal fluid leak (range = 0.8% to 7.1%). Conclusions: There is a lack of consistency in reporting of AEs among RCTs of cervical arthroplasty. FDA IDE trials scored better in AE event reporting compared to other studies. Standardized definitions for AEs and standardized data collection methodology are needed to improve future studies.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/2192568217720681" target="_blank" rel="noreferrer noopener">10.1177/2192568217720681</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
adverse events
Benzel Edward C
cervical disc arthroplasty
complications
Global spine journal
Goel Chandni
industry funding
Mroz Thomas E
Shriver Michael F
Steinmetz Michael P
systematic review
Tanenbaum Joseph E
Xu Jordan C
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/mms.12476" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/mms.12476</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
347-364
Issue
2
Volume
34
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Title
A name given to the resource
Age estimation in bowhead whales using tympanic bulla histology and baleen isotopes
Publisher
An entity responsible for making the resource available
Marine Mammal Science
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
Arctic; Balaena; Balaena mysticetus; bone; carbon; corpora; GLGs; growth; LAGs; layers; Marine & Freshwater Biology; minke whales; stable isotopes; tympanic bulla; Zoology
Creator
An entity primarily responsible for making the resource
Sensor J D; George J C; Clementz M T; Lovano D M; Waugh D A; Givens G H; Suydam R; Stimmelmayr R; Thewissen J G M
Description
An account of the resource
Tympanic bullae and baleen plates from bowhead whales of the Western Arctic population were examined. Growth layer groups (GLGs) in the involucrum of the tympanic bone were used to estimate age of the whales, and compared to stable isotope signatures along transects of baleen plates and the involucrum. The involucrum of the tympanic bone consists of three regions that form in utero, during nursing in the first year, and during the first decades of life, respectively. Life history events, such as annual migration, are recorded in the bowhead tympanic bulla. It is likely that bone growth in the bowhead tympanic occurs during periods of high food intake, while slow or arrested growth occurs during periods of low food intake. Comparisons between numbers of GLGs in the tympanic, number of isotopic oscillations in a baleen plate, length of the baleen plate, and total whale length show correlation coefficients as high as 0.97. The tympanic GLG method is particularly useful for estimating the age of whales up to 20 yr old.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/mms.12476" target="_blank" rel="noreferrer noopener">10.1111/mms.12476</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Arctic
Balaena
Balaena mysticetus
Bone
carbon
Clementz M T
corpora
George J C
Givens G H
GLGs
growth
Journal Article
LAGs
layers
Lovano D M
Marine & Freshwater Biology
Marine Mammal Science
minke whales
Sensor J D
Stable isotopes
Stimmelmayr R
Suydam R
Thewissen J G M
tympanic bulla
Waugh D A
Zoology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.neuro.2018.01.008" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.neuro.2018.01.008</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
125-134
Volume
65
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Title
A name given to the resource
Ahr And Cyp1a2 Genotypes Both Affect Susceptibility To Motor Deficits Following Gestational And Lactational Exposure To Polychlorinated Biphenyls
Publisher
An entity responsible for making the resource available
Neurotoxicology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-03
Subject
The topic of the resource
Aryl hydrocarbon receptor; Cerebellum; CYP1A2; developmental exposure; dioxin-like compounds; dopamine concentrations; in-utero; Motor function; Neurosciences & Neurology; Nigrostriatal pathways; parkinsons-disease; pcb exposure; perinatal exposure; Pharmacology & Pharmacy; Polychlorinated biphenyls; prenatal exposure; risk assessment; school-age; Toxicology
Creator
An entity primarily responsible for making the resource
Colter B T; Garber H F; Fleming S M; Fowler J P; Harding G D; Hooven M K; Howes A A; Infante S K; Lang A L; MacDougall M C; Stegman M; Taylor K R; Curran C P
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.neuro.2018.01.008" target="_blank" rel="noreferrer noopener">10.1016/j.neuro.2018.01.008</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2018
Aryl hydrocarbon receptor
Cerebellum
Colter B T
Curran C P
CYP1A2
Department of Pharmaceutical Sciences
developmental exposure
dioxin-like compounds
dopamine concentrations
Fleming S M
Fowler J P
Garber H F
Harding G D
Hooven M K
Howes A A
in-utero
Infante S K
Lang A L
MacDougall M C
Motor function
NEOMED College of Pharmacy
Neurosciences & Neurology
Neurotoxicology
Nigrostriatal pathways
parkinsons-disease
pcb exposure
perinatal exposure
Pharmacology & Pharmacy
Polychlorinated biphenyls
prenatal exposure
Risk Assessment
school-age
Stegman M
Taylor K R
Toxicology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.2105/AJPH.2018.304457e" target="_blank" rel="noreferrer noopener">http://doi.org/10.2105/AJPH.2018.304457e</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
E9-E9
Issue
8
Volume
108
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
AJPH Global News (vol 108, 838, 2018)
Publisher
An entity responsible for making the resource available
American Journal of Public Health
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-08
Subject
The topic of the resource
New York; Environmental & Occupational Health; Public; Medical Sciences; Service introduction
Creator
An entity primarily responsible for making the resource
Davila M G; Polanco V P; Segura L; Kingsbury D
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.2105/AJPH.2018.304457e" target="_blank" rel="noreferrer noopener">10.2105/AJPH.2018.304457e</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2018
American journal of public health
Davila M G
Department of Family & Community Medicine
Environmental & Occupational Health
Journal Article or Conference Abstract Publication
Kingsbury D
MEDICAL sciences
NEOMED College of Medicine
New York
Polanco V P
Public
Segura L
Service introduction
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
318A-318A
Volume
42
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
ALCOHOL IMPAIRS THE GRANULOPOIETIC RESPONSE TO SEPTIC INFECTION BY DISRUPTING SONIC HEDGEHOG SIGNALING IN HEMATOPOIETIC STEM CELLS
Publisher
An entity responsible for making the resource available
Alcoholism-Clinical and Experimental Research
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-06
Subject
The topic of the resource
Substance Abuse
Creator
An entity primarily responsible for making the resource
Shi X; Zhang P
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Alcoholism-Clinical and Experimental Research
Journal Article
Shi X
Substance Abuse
Zhang P
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
S295-S295
Volume
66
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Title
A name given to the resource
Aldose reductase driven changes in genes linked to fatty acid metabolism and cellular senescence in high fat diet fed mice
Publisher
An entity responsible for making the resource available
Journal of the American Geriatrics Society
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-04
Subject
The topic of the resource
Geriatrics & Gerontology
Creator
An entity primarily responsible for making the resource
Sekaran K; Thiagarajan D; Ramasamy R
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article
2018
Geriatrics & Gerontology
Journal Article
Journal of the American Geriatrics Society
Ramasamy R
Sekaran K
Thiagarajan D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.ijcard.2018.02.053" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.ijcard.2018.02.053</a>
Pages
168–169
Volume
259
Dublin Core
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Title
A name given to the resource
AMP-activated kinase "Keaps" ischemia/reperfusion-induced necroptosis under control.
Publisher
An entity responsible for making the resource available
International journal of cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-05
Subject
The topic of the resource
*AMP-Activated Protein Kinases; *AMPK; *Apoptosis; *Ischemia/reperfusion; *Myocardium; *Necroptosis; *Necrosis; Apoptosis; Humans; Myocardial Reperfusion Injury; Myocardium
Creator
An entity primarily responsible for making the resource
Kanugula Anantha K; Thodeti Charles K
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.ijcard.2018.02.053" target="_blank" rel="noreferrer noopener">10.1016/j.ijcard.2018.02.053</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*AMP-Activated Protein Kinases
*AMPK
*Apoptosis
*Ischemia/reperfusion
*Myocardium
*Necroptosis
*Necrosis
2018
Apoptosis
Department of Integrative Medical Sciences
Humans
International journal of cardiology
Kanugula Anantha K
Myocardial Reperfusion Injury
Myocardium
NEOMED College of Medicine
Thodeti Charles K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.pec.2018.05.005" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.pec.2018.05.005</a>
Pages
1879–1880
Issue
10
Volume
101
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
An N of one.
Publisher
An entity responsible for making the resource available
Patient education and counseling
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-10
Creator
An entity primarily responsible for making the resource
O'Donnell Elizabeth A
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.pec.2018.05.005" target="_blank" rel="noreferrer noopener">10.1016/j.pec.2018.05.005</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Department of Family & Community Medicine
NEOMED College of Medicine
O'Donnell Elizabeth A
Patient education and counseling
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00467-018-4061-9" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00467-018-4061-9</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
An update on LDL apheresis for nephrotic syndrome.
Publisher
An entity responsible for making the resource available
Pediatric nephrology (Berlin, Germany)
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
The topic of the resource
Focal segmental glomerulosclerosis; Hyperlipidemia; Liposorber(R) LA-15 System; Low-density lipoprotein apheresis; Nephrotic syndrome; Podocyte injury
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Krishnappa Vinod
Description
An account of the resource
Low-density lipoprotein (LDL) apheresis has been used increasingly in clinical practice for the treatment of renal diseases with nephrotic syndrome (NS), specifically focal segmental glomerulosclerosis (FSGS). Persistent hyperlipidemia for prolonged periods is nephrotoxic and leads to chronic progressive glomerular and tubulointerstitial injury. Effective management of hyperlipidemia with
Identifier
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<a href="http://doi.org/10.1007/s00467-018-4061-9" target="_blank" rel="noreferrer noopener">10.1007/s00467-018-4061-9</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Department of Internal Medicine
Focal segmental glomerulosclerosis
Hyperlipidemia
Krishnappa Vinod
Liposorber(R) LA-15 System
Low-density lipoprotein apheresis
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Nephrotic syndrome
Pediatric nephrology (Berlin, Germany)
Podocyte injury
Raina Rupesh
-
Text
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URL Address
<a href="http://doi.org/10.1097/AAP.0000000000000818" target="_blank" rel="noreferrer noopener">http://doi.org/10.1097/AAP.0000000000000818</a>
Pages
869–874
Issue
8
Volume
43
Dublin Core
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Title
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Anatomical Look Into OnabotulinumtoxinA Injection for Chronic Migraine Headache.
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Regional anesthesia and pain medicine
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-11
Subject
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80 and over; 80 and Over; Adolescence; Adolescent; Adult; Aged; Anatomic Landmarks/anatomy & histology/*diagnostic imaging; Body Regions; Body Regions – Anatomy and Histology; Botulinum Toxins; Botulinum Toxins – Administration and Dosage; Chronic Disease; Female; Human; Humans; Male; Middle Age; Middle Aged; Migraine; Migraine – Drug Therapy; Migraine Disorders/*diagnostic imaging/*drug therapy; Neck Muscles; Neck Muscles – Anatomy and Histology; Neck Muscles – Drug Effects; Neck Muscles/anatomy & histology/*diagnostic imaging/drug effects; Pilot Projects; Pilot Studies; Random Allocation; Random Assignment; Tomography; Type A/*administration & dosage; X-Ray Computed – Methods; X-Ray Computed/methods; Young Adult
Creator
An entity primarily responsible for making the resource
Wu-Fienberg Yuewei; Ansari Hossein; Zardouz Shawn; Narouze Samer; Blaha Taryn; Swanson Marco; Totonchi Ali
Description
An account of the resource
BACKGROUND AND OBJECTIVES: While existing studies about onabotulinumtoxinA for chronic migraines have focused on injection location and appropriate dosing, little consideration has been given to patient body habitus and its potential impact on efficacy. We hypothesized that with increasing patient body mass index (BMI) there would be more subcutaneous fat separating targeted muscle groups from the skin surface, such that standard 0.5-inch needles used in existing protocols may not allow intramuscular injection. This may have implications for treatment planning. METHODS: Anatomically normal computed tomography scans of the head, neck, and face were randomly selected. Subjects were stratified into 4 groups based on BMI, with 30 patients in each group. Four standardized locations were chosen to obtain measurements from the skin surface to the underlying muscle fascia, including (1) frontalis, (2) temporalis, (3) semispinalis capitis, and (4) trapezius. RESULTS: Median depth for the temporalis was 12.65 mm (Q1 = 9.32 mm, Q3 = 15.08 mm) for the BMI greater than 35 kg/m group. Median depth for the semispinalis capitis was 13.77 mm (Q1 = 10.3 mm, Q3 = 15.7 mm) for the BMI 30 to 35 kg/m group, and 14.75 mm (Q1 = 11.00, Q3 = 17.00 mm) for the BMI greater than 35 kg/m group. Median depth for the trapezius was 13.95 mm (Q1 = 10.18 mm, Q3 = 19.00 mm) for the BMI greater than 35 kg/m group. These medians exceeded the length of the standard 0.5-inch (12.-mm) needle used in existing protocols. CONCLUSIONS: Our study demonstrates that with increasing BMI there is a greater distance between the skin surface and the muscle fascia of muscles that are targeted for injection in standard chronic migraine botulinum toxin injection protocols. Because of this, patient body habitus may be an important factor in injection technique.
Identifier
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<a href="http://doi.org/10.1097/AAP.0000000000000818" target="_blank" rel="noreferrer noopener">10.1097/AAP.0000000000000818</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
80 and over
Adolescence
Adolescent
Adult
Aged
Anatomic Landmarks/anatomy & histology/*diagnostic imaging
Ansari Hossein
Blaha Taryn
Body Regions
Body Regions – Anatomy and Histology
Botulinum Toxins
Botulinum Toxins – Administration and Dosage
Chronic Disease
Female
Human
Humans
Male
Middle Age
Middle Aged
Migraine
Migraine – Drug Therapy
Migraine Disorders/*diagnostic imaging/*drug therapy
Narouze Samer
Neck Muscles
Neck Muscles – Anatomy and Histology
Neck Muscles – Drug Effects
Neck Muscles/anatomy & histology/*diagnostic imaging/drug effects
Pilot Projects
Pilot Studies
Random Allocation
Random Assignment
Regional anesthesia and pain medicine
Swanson Marco
Tomography
Totonchi Ali
Type A/*administration & dosage
Wu-Fienberg Yuewei
X-Ray Computed – Methods
X-Ray Computed/methods
Young Adult
Zardouz Shawn
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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Title
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Anatomy, Bony Pelvis and Lower Limb, Calf Deep Peroneal (Fibular) Nerve
Publisher
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StatPearls
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-01
Creator
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Garrett Alexandrea; Geiger Zachary
Description
An account of the resource
The deep peroneal nerve is also known as the deep fibular nerve. It originates after the bifurcation of the common peroneal nerve between the upper segment of the peroneus longus and the head of the fibula.[1] The common peroneal nerve (spinal nerves L4 through S1) itself originates from the bifurcation of the sciatic nerve (spinal nerves L4 through S3) which terminates at the apex of the popliteal fossa into the common peroneal and the tibial nerve after wrapping around the neck of the fibula.[2],[3] After bifurcation from the common peroneal nerve, the deep peroneal nerve then traverses deep to the extensor digitorum longus and runs on the anterior surface of the interosseous membrane.[1] In the middle of the leg, it is in close association with the anterior tibial artery and then descends with the artery to lie in front of the ankle joint. Here, it gives off the lateral and medial terminal branches. The medial terminal branch accompanies the dorsalis pedis and runs on the dorsum of the foot reaching the first interosseous space where it divides into digital nerves that supply the side of the great and second toes. The lateral terminal branch runs beneath the extensor digitorum brevis and gives off interosseous branches that supply the tarsal and metatarsophalangeal joints.[1]
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Garrett Alexandrea
Geiger Zachary
StatPearls
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Anatomy, Bony Pelvis and Lower Limb, Superficial Peroneal (Fibular) Nerve
Publisher
An entity responsible for making the resource available
StatPearls
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-01
Creator
An entity primarily responsible for making the resource
Garrett Alexandrea; Geiger Zachary
Description
An account of the resource
The superficial peroneal nerve is also known as the superior fibular nerve. The superficial peroneal nerve originates from the common peroneal nerve alongside the deep peroneal nerve. The superficial peroneal nerve is the smaller of the two nerves.[1] The common peroneal nerve is comprised of fibers from spinal nerves L4 through S1 which itself originates from the bifurcation of the sciatic nerve which is composed of nerve fibers from spinal nerves L4 through S3. The sciatic nerve terminates and bifurcates at the apex of the popliteal fossa and becomes the common peroneal nerve and the tibial nerve as it wraps around the fibular neck.[2][3] After bifurcation from the common peroneal, the superficial peroneal nerve courses within the peroneus longus muscle.[1] This nerve thus provides motor innervation to the peroneus longus muscle. Additionally, the nerve also innervates the peroneus brevis muscle.[1] The nerve exits through the peroneal muscles on the anterolateral aspect of the lower half of the lower leg approximately 12 cm above the ankle joint at a defect in the crural fascia also known as the deep fascia of the leg.[1] The remainder of the nerve has sensory function provided by two branches inferiorly which are known as the medial dorsal cutaneous nerve (the larger of the two branches) and the intermediate dorsal cutaneous nerve. These nerves provide sensory innervation to the anterolateral aspect of the leg, the dorsum of the foot, and the dorsal aspect of the toes with the exception of the first web space.[1] The first web space is innervated by the dorsal peroneal nerve.[4]
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Garrett Alexandrea
Geiger Zachary
StatPearls
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Anatomy, Head and Neck, Deep Petrosal Nerve
Publisher
An entity responsible for making the resource available
StatPearls
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-01
Creator
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Goosmann Madeline M; Dalvin Mark
Description
An account of the resource
The deep petrosal nerve is a branch from the internal carotid plexus.[1] The plexus is located on the lateral side of the internal carotid as it courses superiorly. The deep petrosal enters the skull through the carotid canal with the internal carotid artery.[1] Without passing completely through the carotid canal, the deep petrosal travels perpendicular to the canal in another bony canal called foramen lacerum. The foramen lacerum is closed with cartilaginous substance superficially. The location of this foramen is between the body of sphenoid where the greater wing of the sphenoid and pterygoid plate meets anteriorly, petrous temporal bone laterally, and basilar occipital bone medially.[1] In foramen lacerum, the deep petrosal nerve joins with the greater petrosal nerve to form the vidian nerve also called the nerve of the pterygoid canal.[1][2][3] The vidian nerve carries parasympathetic and sympathetic fibers through the pterygoid canal to the pterygopalatine ganglion, otherwise known as the sphenopalatine ganglion.[4] Parasympathetic fibers synapse in the pterygopalatine ganglion, whereas sympathetic fibers pass through without synapsing.[1][5] The fibers carried by the deep petrosal nerve originated in the intermediate gray horn of the spinal cord around the level of T1, traveled superiorly through the sympathetic chain, and synapsed in the superior cervical ganglion located around the level of C2-C3.[1] Because the sympathetic fibers have already synapsed, they do not synapse again in the pterygopalatine ganglion. The sympathetic fibers continue after the pterygopalatine ganglion to run along the zygomatic nerve to blood vessels and secretomotor elements in the lacrimal gland, nose, and oral cavity.[1]
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Dalvin Mark
Goosmann Madeline M
StatPearls
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Anatomy, Thorax, Mediastinal Lymph Nodes
Publisher
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StatPearls
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-01
Creator
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Burlew Jacob T; Banks Kevin P
Description
An account of the resource
The mediastinal compartment contains multiple critical organs and vessels and serves as the central hub for lymphatic drainage. The mediastinum is classically subdivided into three functional divisions: anterior (pre-vascular), middle (visceral), and posterior (paravertebral) mediastinum. These subdivisions are used to describe the locations of lesions, thereby helping to facilitate a differential diagnosis and communication between providers. Lymph nodes (LNs) are present in all three functional compartments of the mediastinum, though most lymphatic tissue is found in the anterior and middle compartments, and the etiology of lymphatic pathology varies by subdivision. Dividing the mediastinum helps to narrow down the lengthy differential diagnoses which can present in the thorax (including, but not limited to: infections like tuberculosis, nodal spread of lung cancer, sarcoidosis, lymphoma, silicosis, and asbestosis). In contrast to the functional subdivisions, intrathoracic LN locations have been traditionally mapped into 14 stations according to their relationship to landmarks encountered during mediastinoscopy and thoracotomy for lung cancer. Stations 1-9 correspond to mediastinal nodal groups, while stations 10-14 represent hilar and other more peripheral extra mediastinal nodal groups. The most current map of intrathoracic lymph nodes is the International Association for the Study of Lung Cancer (IASLC) map. The IASLC atlas supersedes all previous schema and reconciles discrepancies among older popular systems such as the Naruke lymph node classification and the Mountain-Dresler modified version of the American Thoracic Society lymph node map.[1][2][3][4]
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Banks Kevin P
Burlew Jacob T
StatPearls
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/978-1-4939-7407-8_15" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/978-1-4939-7407-8_15</a>
Pages
171–185
Volume
1695
Dublin Core
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Title
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Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma.
Publisher
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Methods in molecular biology (Clifton, N.J.)
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
*Axonal transport; *Axonopathy; *Neuronal tracing; *Optic nerve; *Superior colliculus; Animal; Animals; Axonal Transport; Axons/metabolism/*pathology/physiology; Cholera Toxin/*metabolism; Confocal; Disease Models; Glaucoma/*diagnostic imaging/metabolism/physiopathology; Humans; Mice; Microscopy; Rats; Visual Pathways
Creator
An entity primarily responsible for making the resource
Crish Samuel D; Schofield Brett R
Description
An account of the resource
Whether to stage degeneration or investigate early pathology in glaucoma, examination of axonal structure and function is essential. There are a wide variety of methods available to investigators using animal models of glaucoma, with varying utilities depending on the questions asked. Here, we describe the use of anterograde neuronal tract tracing using cholera toxin B (CTB) for the determination of axon transport integrity of the retinofugal projection. This method reveals the structure of the retinal axons as well as the functional integrity of anterograde transport systems.
Identifier
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<a href="http://doi.org/10.1007/978-1-4939-7407-8_15" target="_blank" rel="noreferrer noopener">10.1007/978-1-4939-7407-8_15</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Axonal transport
*Axonopathy
*Neuronal tracing
*Optic nerve
*superior colliculus
2018
Animal
Animals
Axonal Transport
Axons/metabolism/*pathology/physiology
Cholera Toxin/*metabolism
Confocal
Crish Samuel D
Department of Anatomy & Neurobiology
Department of Pharmaceutical Sciences
Disease Models
Glaucoma/*diagnostic imaging/metabolism/physiopathology
Humans
Methods in molecular biology (Clifton, N.J.)
Mice
Microscopy
NEOMED College of Medicine
NEOMED College of Pharmacy
Rats
Schofield Brett R
Visual Pathways
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1177/2054358118792229" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/2054358118792229</a>
Pages
2054358118792229–2054358118792229
Volume
5
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Antibiotic Dosing in Sustained Low-Efficiency Dialysis in Critically Ill Patients.
Publisher
An entity responsible for making the resource available
Canadian journal of kidney health and disease
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
1905-07
Subject
The topic of the resource
antibiotics; extended daily dialysis; pharmacokinetics; SLED; sustained low-efficiency dialysis
Creator
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Sethi Sidharth Kumar; Krishnappa Vinod; Nangethu Nisha; Nemer Paul; Frazee Lawrence A; Raina Rupesh
Description
An account of the resource
Purpose of review: Sustained low-efficiency dialysis (SLED) is increasingly used as a renal replacement modality in critically ill patients with acute kidney injury (AKI) and hemodynamic instability. There is, therefore, a greater need for the understanding of the antibiotic dosage and pharmacokinetics in these patients, to provide them with optimal therapy. Sources of information: PubMed/Medline, Embase, and Google Scholar. Methods: PubMed/Medline, Embase, and Google Scholar databases were searched using a combination of key words: dialysis, end stage renal disease, renal failure, sustained low efficiency dialysis, extended daily dialysis, prolonged intermittent renal replacement therapy (PIRRT), and antibiotic dosing. Studies that investigated antibiotic dosing and pharmacokinetics during SLED/extended daily dialysis/PIRRT were selected for this review. Key findings: Eleven studies met inclusion criteria and selected for data extraction. The data with regard to dialysis specifications, type of antibiotic including dosages, drug clearances, and dosage recommendations are summarized in Table 1. It is a challenge to find therapeutic doses for antibiotics during SLED therapy because, in general, only aminoglycosides and vancomycin can be assayed in clinical laboratories. Limitations: Although current studies on antibiotic dosing in SLED are limited due to diverse and undersized patient populations, antibiotic dosage adjustments for patients receiving SLED discussed here will serve as a valuable guide. Future large-scale research should focus on establishing guidelines for antibiotic dosage in SLED. Implications: Pharmacokinetic principles should be taken into consideration for the appropriate dosing of drugs during SLED, yet it is vital to monitor response to drug to make sure therapeutic goals are achieved. Antibiotic dosing and timing relative to the initiation of SLED may be important to maximize either the time above the minimum inhibitory concentration (MIC) (time-dependent) or the peak to MIC ratio (concentration-dependent), balancing efficacy and toxicity concerns. Critical care physicians should liaise with nephrologists to make decisions regarding appropriate antibiotic dosing in patients undergoing SLED.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1177/2054358118792229" target="_blank" rel="noreferrer noopener">10.1177/2054358118792229</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Antibiotics
Canadian journal of kidney health and disease
Department of Internal Medicine
extended daily dialysis
Frazee Lawrence A
Krishnappa Vinod
Nangethu Nisha
Nemer Paul
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
pharmacokinetics
Raina Rupesh
Sethi Sidharth Kumar
SLED
sustained low-efficiency dialysis