Browse Items · NEOMED Bibliography Database

SENTINEL1: Two-Season Study of Respiratory Syncytial Virus Hospitalizations among U.S. Infants Born at 29 to 35 Weeks' Gestational Age Not Receiving Immunoprophylaxis.

OBJECTIVE: The SENTINEL1 observational study characterized confirmed respiratory syncytial virus hospitalizations (RSVH) among U.S. preterm infants born at 29 to 35 weeks' gestational age (wGA) not receiving respiratory syncytial virus (RSV) …

MITOCHONDRIAL DYSFUNCTION IN OSTEOARTHRITIS AND AGED CARTILAGE TRIGGERS INFLAMMATORY RESPONSE AND MATRIX DEGRADATION VIA ROS MEDIATED ACTIVATION OF JNK-MAPK/CFOS-AP1 AXIS IN CHONDROCYTES

Tags: 2020, Ahmad N, Ansari M Y, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Haqqi Tariq M, Journal Article, journalArticle, June 2020 Update I, Malik M, Nationwide Children's Hospital, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED College of Pharmacy, NEOMED Student Publications, Novak K, Osteoarthritis and cartilage, Voleti S, Wase S

Mitochondrial dysfunction triggers catabolic response in chondrocytes via ROS mediated activation of JNK/AP1 pathway.

Mitochondrial function is impaired in osteoarthritis (OA) but its impact on cartilage catabolism is not fully understood. Here, we investigated the molecular mechanism of mitochondrial dysfunction-induced activation of catabolic response in …

Tags: 2020, Ahmad N, Ansari M Y, cFos-AP1, Chondrocytes, Department of Anatomy & Neurobiology, Haqqi TM, Inflammation, JNK, Journal of Cell Science, journalArticle, NEOMED College of Medicine, NEOMED Student Publications, Novak K, October 2020 List, Osteoarthritis, Redox, Voleti S, Wase SJ

Lysosomal dysfunction in osteoarthritis and aged cartilage triggers apoptosis in chondrocytes through BAX mediated release of cytochrome c.

OBJECTIVE: Lysosomes are the major catabolic organelle of the cell and regulate the macromolecular and organelle turnover and programmed cell death. Here, we investigated the lysosome dysfunction in cartilage and its role in chondrocytes apoptosis…

Tags: 2020, ageing, Ansari M Y, Apoptosis, Ball HC, Bax, Department of Anatomy & Neurobiology, Haqqi TM, journalArticle, Lysosomal dysfunction, Mitochondrial dysfunction, NEOMED College of Medicine, NEOMED Student Publications, Novak K, October 2020 List, Osteoarthritis, Osteoarthritis and cartilage, Wase SJ

First person - Mohammad Yunus Ansari

Tags: 2020, Ansari MY, Department of Anatomy & Neurobiology, January 2021 List, Journal of Cell Science, journalArticle, NEOMED College of Medicine

Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols.

Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible structural and functional changes in the joint and is a major cause of disability and reduced life expectancy in ageing population. Despite the high …

Tags: 2020, Ahmad N, Ansari MY, August 2020 List, Biomedicine & Pharmacotherapy, Chondrocytes, Department of Anatomy & Neurobiology, Haqqi TM, Inflammation, journalArticle, NEOMED College of Medicine, Nrf2, Osteoarthritis, Polyphenols, Redox

Assessing chondrocyte status by immunofluorescence-mediated localization of parkin relative to mitochondria.

Tags: 2020, Autophagy, CCCP, Chondrocytes, Confocal microscopy, IL-1β, immunofluorescence, Inflammation, Mitochondria, Mitochondrial dysfunction, mitophagy, MitoTracker Deep Red, Osteoarthritis, Oxidative Stress, Parkin, PINK1

Measuring acetyl-coa and acetylated histone turnover in vivo: Effect of a high fat diet.

Cellular availability of acetyl-CoA, a central intermediate of metabolism, regulates histone acetylation. The impact of a high-fat diet (HFD) on the turnover rates of acetyl-CoA and acetylated histones is unknown. We developed a method for…

Tags: 2020, Acetyl-CoA, Acetylation, Heavy water, High resolution mass spectrometry, Histone, Turnover

Association between neighborhood disadvantage and fulfillment of desired postpartum sterilization.

BACKGROUND: Adequacy of prenatal care is associated with fulfillment of postpartum sterilization requests, though it is unclear whether this relationship is indicative of broader social and structural determinants of health or reflects the…

Tags: 2020, Arora KS, Ascha M, BMC Public Health, Einstadter D, Hospital List, journalArticle, Medicaid, Montague M, Morris J, Neighborhood disadvantage, Postpartum contraception, Social Determinants of Health, Sterilization, Verbus E, Wilkinson B

Evaluation of anticoagulation practice with new-onset atrial fibrillation in patients with sepsis and septic shock in medical intensive care unit: A retrospective observational cohort study.

Objective To investigate the anticoagulation practice in patients presenting with new-onset atrial fibrillation (NOAF) during sepsis and septic shock with one-year follow-up since discharge and to evaluate factors associated with the development of…

Tags: 2020, Anticoagulation, Arunachalam K, Atrial fibrillation, Critical Care, Cureus, Department of Internal Medicine, Jha K, journalArticle, Kalyan SA, NEOMED College of Medicine, Pond K, September 2020 List, Septic shock, severe sepsis, Thakur L

Neonatal outcomes in obese pregnant women who develop preeclampsia.

OBJECTIVE: Obesity and preeclampsia in pregnant women are each independently associated with poorer neonatal outcomes. We study obesity and preeclampsia alone and also in combination in pregnant women to determine their association with neonatal…

Tags: 2020, Asemota O, August 2020 List, Bryson L, Fogel J, journalArticle, NEOMED College of Medicine Student, NEOMED Student Publications, Neonatal ICU, neonate, Obesity, pre-eclampsia, Pregnancy Hypertension

Does using humor to cope with stress justify making fun of patients?

This article considers 3 reasons for derogatory humor in clinical settings and argues that when such humor is directed at patients without understanding their complex histories, it can diminish the therapeutic relationship rather than serve as a…

Tags: 2020, American Medical Association Journal of Ethics, August 2020 List, Aultman JM, Department of Family & Community Medicine, journalArticle, Meyers E, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications

The segregated gun as an indicator of racism and representations in film

Film emphasizes an ironic history of racism in gun control and ownership and a justification for seeking justice among the Black community, but film also perpetuates structural racism and bias, segregating Black from White, and failing to promote…

Tags: 2020, August 2020 List, Aultman JM, Department of Family & Community Medicine, Humanities & Social Sciences Communications, journalArticle, magical negro, NEOMED College of Graduate Studies, NEOMED College of Medicine, Piatt E, Piatt J, Race

Reimagining proactive strategic planning toward patient-centered care: processes and outcomes in a medical school's department of family and community medicine

Purpose A detailed strategic planning process is presented that entails several beneficial and effective strategies and goals for interdisciplinary academic, clinical and/or service departments. This strategic planning process emerged due to the need…

Tags: 2020, Aultman Julie, Baughman Kristin, Boltri John M, Clinical leadership, Department of Family & Community Medicine, family medicine, Fischbein Rebecca, Health professions, International Journal of Health Governance, Kingsbury Diana, Medical education, NEOMED College of Graduate Studies, NEOMED College of Medicine, Organizational development for effective clinical governance, Organizational learning, primary care

A Call for Diversity and Inclusivity in the HEC-C Program.

Tags: 2020, Aultman Julie, Bioethics, Certification, Consultants, Department of Family & Community Medicine, ETHICAL decision making, ETHICISTS, Humans, MEDICAL consultants, MEDICAL ethics, NATIONAL competency-based educational tests, NEOMED College of Graduate Studies, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Pathmathasan Cynthia, PROFESSIONAL licensure examinations, The American journal of bioethics : AJOB

Evaluation of the reproducibility of bolus transit quantification with contrast-enhanced ultrasound across multiple scanners and analysis software packages-a quantitative imaging biomarker alliance study.

Objectives: Contrast enhanced ultrasound (CEUS) is now broadly used clinically for liver lesion detection and characterization. Obstacles to the efforts to quantify perfusion with CEUS have been the lack of a standardized approach and undocumented…

Tags: 2020, Averkiou MA, Barr RG, Carson PL, Cuevas MA, Department of Radiology, Gallagher MK, Investigative Radiology, journalArticle, Juang EK, NEOMED College of Medicine, September 2020 List, Wilson SR

Safety of bariatric surgery in patients with inflammatory bowel disease: A systematic review and meta-analysis.

The efficacy of bariatric surgery in achieving weight loss and preventing long-term comorbidities such as cardiovascular diseases, diabetes mellitus and osteoarthritis is well established. Data regarding safety of bariatric surgery in patients with…

Tags: 2020, Aziz M, Bariatric Surgery, Chandan S, Clinical Obesity, Crohn's disease, Fatima R, Haghbin H, Hassan M, Hospital List, inflammatory bowel disease, Ishtiaq R, journalArticle, Lee-Smith W, Mohan BP, Nawras A, Sharma S, ulcerative colitis

A Simulation Model for External Cephalic Version

Breech presentation complicates as many as 4% of all deliveries. External cephalic version (ECV) is a procedure that involves the external rotation of the fetus through the mother's abdomen from a breech position into a cephalic position. It provides…

Tags: 2020, Baaklini Carla, Ballas DA, Cureus, Department of Obstetrics & Gynecology, Education, external cephalic version, February 2021 List, journalArticle, Larios JT, Menassa N, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, simulation, training model

Updated guidance on the management of covid-19: From an American Thoracic Society/European Respiratory Society coordinated international task force (29 july 2020).

Background: Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome-coronavirus-2. Consensus suggestions can standardise care, thereby improving outcomes and facilitating future research.; Methods: An…

Small non-coding RNAome of ageing chondrocytes.

Ageing is a leading risk factor predisposing cartilage to osteoarthritis. However, little research has been conducted on the effect of ageing on the expression of small non-coding RNAs (sncRNAs). RNA from young and old chondrocytes from …

Impact of a Novel Post-Discharge Transitions of Care Clinic on Hospital Readmissions.

BACKGROUND: The Center for Medicare and Medicaid Services (CMS) has targeted hospital readmissions, which cost $17 billion per year, as one potential solution to reduce rising health care costs. Studies have documented the ability of Transitions …

A retrotransposon gag-like-3 gene RTL3 and SOX-9 co-regulate the expression of COL2A1 in chondrocytes.

PURPOSE: Transposable elements are known to remodel gene structure and provide a known source of genetic variation. Retrotransposon gag-like-3 (RTL3) is a mammalian retrotransposon-derived transcript (MART) whose function in the skeletal tissue is …

Evidence for independent peripheral and central age-related hearing impairment.

Deleterious age-related changes in the central auditory nervous system have been referred to as central age-related hearing impairment (ARHI) or central presbycusis. Central ARHI is often assumed to be the consequence of peripheral ARHI. However, it…

Mitochondrial diseases in North America: An analysis of the NAMDC Registry.

Objective: To describe clinical, biochemical, and genetic features of participants with mitochondrial diseases (MtDs) enrolled in the North American Mitochondrial Disease Consortium (NAMDC) Registry. Methods: This cross-sectional, multicenter,…

Tags: 2020, Akron Children's Hospital, Barca Emanuele, Bedoyan Jirair K, Buchsbaum Richard, Camp Kathryn, Cohen Bruce H, Cooley Victoria, criteria, DeBrosse Susanne D, Department of Integrative Medical Sciences, Department of Pediatrics, DiMauro Salvatore, DNA, Emmanuele Valentina, Engelstad Kristin, Enns Gregory M, Falk Marni J, Ganesh Jaya, Gavrilova Ralitza H, Goldstein Amy C, Grier Johnston, Gropman Andrea, Haas Richard, Hirano Michio, Journal Article, journalArticle, June 2020 Update I, Karaa Amel, Kriger Joshua, Krotoski Danuta, Larson Austin, Long Yuelin, melas, merrf, natural-history, NEOMED College of Medicine, Neurology. Genetics, nuclear, Parikh Sumit, Prevalence, Rosales Xiomara Q, Saneto Russell P, Scaglia Fernando, Schoenaker Robert, Stacpoole Peter W, Tarnopolsky Mark, Thompson John L P, Van Hove Johan L K, Vladutiu Georgirene D, Zolkipli-Cunningham Zarazuela

Update to the society of radiologists in ultrasound liver elastography consensus statement.

This multidisciplinary update of the Society of Radiologists in Ultrasound consensus statement on liver elastography incorporates the large volume of new information available in the literature since the initial publication. The recommended procedure…

Tags: 2020, Barr RG, Department of Family & Community Medicine, Ferraioli G, Garcia-Tsao G, journalArticle, July 2020 List, Mercy Health St Elizabeth Boardman Hospital, NEOMED College of Medicine, Radiology, Rubens D, Wilson SR

Contrast-enhanced ultrasound: State of the art in North America

On October 24, 2017, in Chicago, the Society of Radiologists in Ultrasound convened a panel of specialists in contrast-enhanced ultrasound (CEUS) to arrive at a white paper regarding the use of CEUS in noncardiac applications in North America.…

Tags: 2020, Barr RG, Chong WK, Darge K, Department of Radiology, Fleischer A, Grant E, journalArticle, Lyshchik A, McCarville B, Mercy Health St Elizabeth Boardman Hospital, NEOMED College of Medicine, Paltiel HJ, Robbin M, September 2020 List, Ultrasound quarterly, Wilmann JK, Wilson SR

Contrast-enhanced ultrasound: State of the art in North America

The Society of Radiologists in Ultrasound convened a panel of specialists in contrast-enhanced ultrasound (CEUS) to produce a white paper on noncardiac CEUS in North America. The panel met in Chicago, Illinois, on October 24 and 25, 2017. The …

Contrast-enhanced ultrasound imaging of the liver: a review of the clinical evidence for SonoVue and Sonazoid.

Contrast-enhanced ultrasound (CEUS) has become an established modality in various clinical indications for liver diseases. SonoVue((R)), a pure blood pure agent, and Sonazoid((R)), which exhibits an additional Kupffer phase, are contrast agents…

Physicians and duty during pandemics.

Tags: 2020, August 2020 List, Barreiro TJ, Department of Internal Medicine, Duty, Gemmel D, journalArticle, Literature, Mercy Health St Elizabeth Youngstown Hospital, NEOMED College of Medicine, pandemic, The American journal of medicine

Physicians and duty during a pandemic: a response.

Tags: 2020, Barreiro TJ, Department of Internal Medicine, Gemmel D, journalArticle, NEOMED College of Medicine, September 2020 List, The American journal of medicine

Multi-Site Study of Provider Self-Efficacy and Beliefs in Explaining Judgments About Need and Responsibility for Advance Care Planning.

BACKGROUND AND OBJECTIVES: We examined the impact of advance care planning (ACP) self-efficacy and beliefs in explaining skilled nursing facility (SNF) provider judgments about resident need and provider responsibility for initiating ACP …

Tags: 2020, advance care planning, Baughman KR, beliefs, December 2020 List, Decision-making, factorial survey, Jarjoura D, journalArticle, Kropp D, Ludwick R, nurses, self-efficacy, Skilled Nursing Facilities, social workers, The American journal of hospice & palliative care, Yeager M

Retinoic acid receptor α signaling protects against diet‐induced hepatosteatosis and obesity in mice

Nonalcoholic fatty liver disease (NAFLD) is often characterized by accumulation of lipids in the liver. It presents a pathological spectrum of changes from simple steatosis to steatohepatitis. It is also often associated with obesity and insulin…

Tags: 2020, Bawa F, Chen S, Department of Integrative Medical Sciences, Faseb Journal, Gopoju R, journalArticle, NEOMED College of Medicine Student, NEOMED Postdoc Publications, NEOMED Student Publications, September 2020 List, Xu Y, Zhang Y, Zhu Y

Evidence of clonal hematopoiesis and risk of heart failure

Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by persistent clonal expansion of adult hematopoietic stem cells, which has been increasingly found to be associated with cardiovascular disease and adverse outcomes in heart…

Tags: 2020, August 2020 List, Bazeley P, Current Heart Failure Reports, journalArticle, Morales R, NEOMED College of Medicine Student, NEOMED Student Publications, Tang WHW

Carotid Artery Stenting in Asymptomatic Carotid Artery Stenosis: JACC Review Topic of the Week.

The advance of therapies to reduce the stroke impact of asymptomatic carotid artery stenosis has proved difficult over the last decade. Disagreement concerning the underlying randomized control trials has limited entry into the care arena of …

Utility of specific amino acid ratios in screening for pyruvate dehydrogenase complex deficiencies and other mitochondrial disorders associated with congenital lactic acidosis and newborn screening prospects.

Pyruvate dehydrogenase complex deficiencies (PDCDs) and other mitochondrial disorders (MtDs) can (a) result in congenital lactic acidosis with elevations of blood alanine (Ala) and proline (Pro), (b) lead to decreased ATP production, and (c) …

Perineuronal nets and subtypes of GABAergic cells differentiate auditory and multisensory nuclei in the intercollicular area of the midbrain.

The intercollicular region, which lies between the inferior and superior colliculi in the midbrain, contains neurons that respond to auditory, visual, and somatosensory stimuli. Golgi studies have been used to parse this region into three distinct…

Tags: 2020, ab_10807945, ab_141607, ab_2278725, ab_2336066, ab_2336132, ab_2336874, ab_2336875, ab_2336881, ab_2534012, ab_2535710, ab_2665454, ab_2735091, ascending projections, Beebe Nichole L, Department of Anatomy & Neurobiology, descending projections, dorsal column nuclei, efferent connections, external nucleus, extracellular-matrix, Guinea Pigs, inferior colliculus, intercollicular tegmentum, journalArticle, June 2020 Update II, lateral lemniscus, medial geniculate-body, NEOMED College of Medicine, Noftz William A, nucleus of the brachium of the inferior colliculus, rostral pole of the inferior colliculus, rrid, RRID: AB_10807945, RRID: AB_141607, RRID: AB_2278725, RRID: AB_2336066, RRID: AB_2336132, RRID: AB_2336874, RRID: AB_2336875, RRID: AB_2336881, RRID: AB_2534012, RRID: AB_2535710, RRID: AB_2665454, RRID: AB_2735091, RRID: SCR_001775, Schofield Brett R, scr_001775, superior colliculus, The Journal of comparative neurology, VGLUT2

Generation of a ChAT(Cre) mouse line without the early onset hearing loss typical of the C57BL/6J strain.

The development of knockin mice with Cre recombinase expressed under the control of the promoter for choline acetyltransferase (ChAT) has allowed experimental manipulation of cholinergic circuits. However, currently available ChAT(Cre) mouse lines…

Tags: 2020, Acetylcholine, Age-related hearing loss, Beebe Nichole L, Choline acetyltransferase, Cox Brandon C, Department of Anatomy & Neurobiology, Galazyuk Alexander V, Hearing research, Kristaponyte Inga, NEOMED College of Medicine, Normal hearing, Presbycusis, Schofield Brett R, Sowick Colleen S, Transgenic mouse, Vetter Douglas E

Contrast-enhanced ultrasound of renal masses.

Contrast enhanced ultrasound (CEUS) has gained clinical importance over the last years for the characterization of hepatic masses. Its role in extrahepatic indications has been investigated repeatedly but has been less comprehensively studied.…

Tags: 2020, angiomyolipoma, Applied Radiology, Barr RG, Bennett J, Biopsy, Contrast enhanced ultrasound, Department of Radiology, journalArticle, NEOMED College of Medicine, October 2020 List, onocytoma, Peterson C, Renal cell carcinoma, sonovue

Advanced myeloma masquerading as chronic shoulder pain in a 48-year-old man: A diagnostic dilemma.

Although solitary plasmacytomas may occasionally present as collar bone swellings or fractures, multiple myeloma involving clavicle is extremely rare. Ten to forty per cent of multiple myeloma cases are asymptomatic and are incidental diagnoses. Our…

Tags: 2020, Bhadra R, BMJ case reports, cancer - see oncology, Department of Internal Medicine, journalArticle, July 2020 List, malignant disease and immunosuppression, monoclonal gammopathy of undetermined significance associated neuropathy, NEOMED College of Medicine, NEOMED College of Medicine Student, NEOMED Student Publications, Nikova T, Ravakhah K, renal system, Somasundaram M, St Vincent Charity Medical Center

Essential role of neutrophils in the protective immune response induced by a live attenuated leishmania vaccine.

No licensed vaccine exists against visceral leishmaniasis (VL), a disease caused by the Leishmania donovani parasite. We have previously reported both macrophages and dendritic cells play important role in the protection induced by a live…

Tags: 2020, Bhattacharya P, Dagur PK, De Paoli S, Dey R, Gannavaram S, Ismail N, Journal of Immunology, journalArticle, Karmakar S, McCoy JP Jr, Nakhasi HL, NEOMED College of Medicine Student, NEOMED Student Publications, October 2020 List, Satoskar M, Satoskar S, Saxena A, Takeda K

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