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Text
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URL Address
<a href="http://doi.org/10.1016/0006-8993(95)01566-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0006-8993(95)01566-3</a>
Pages
113–118
Issue
1
Volume
715
Dublin Core
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Title
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Effects of testosterone upon MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system of C57/B1 mice.
Publisher
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Brain research
Date
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1996
1996-04
Subject
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*MPTP Poisoning; 1-Methyl-4-phenyl-1; 2; 3; 4-Dihydroxyphenylacetic Acid/metabolism; 6-tetrahydropyridine/*antagonists & inhibitors; Animals; Catecholamines/metabolism; Dopamine Agents/*toxicity; Dopamine/metabolism/*physiology; Female; Inbred C57BL; Male; Mice; Neostriatum/drug effects/metabolism/*pathology; Nervous System Diseases/chemically induced/*pathology/*prevention & control; Olfactory Bulb/drug effects/metabolism; Orchiectomy; Substantia Nigra/drug effects/metabolism/*pathology; Testosterone/*pharmacology
Creator
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Dluzen D E
Description
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We have recently reported that treatment of gonadectomized female and male C57/B1 mice with the gonadal steroid hormone, estrogen, reduced nigrostriatal dopaminergic neurotoxicity resulting from the Parkinson's-like inducing agent
Identifier
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<a href="http://doi.org/10.1016/0006-8993(95)01566-3" target="_blank" rel="noreferrer noopener">10.1016/0006-8993(95)01566-3</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*MPTP Poisoning
1-Methyl-4-phenyl-1
1996
2
3
4-Dihydroxyphenylacetic Acid/metabolism
6-tetrahydropyridine/*antagonists & inhibitors
Animals
Brain research
Catecholamines/metabolism
Dluzen D E
Dopamine Agents/*toxicity
Dopamine/metabolism/*physiology
Female
Inbred C57BL
Male
Mice
Neostriatum/drug effects/metabolism/*pathology
Nervous System Diseases/chemically induced/*pathology/*prevention & control
Olfactory Bulb/drug effects/metabolism
Orchiectomy
Substantia Nigra/drug effects/metabolism/*pathology
Testosterone/*pharmacology