1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
215–219
Issue
1
Volume
741
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The effects of intranasal infusion of
Publisher
An entity responsible for making the resource available
Brain research
Date
A point or period of time associated with an event in the lifecycle of the resource
1996
1996-11
Subject
The topic of the resource
Male; Animals; Mice; Corpus Striatum/drug effects/*metabolism; Dopamine/metabolism; Olfactory Bulb/drug effects/*metabolism; Norepinephrine/metabolism; Injections; Catecholamines/*metabolism; Dopamine Agents/administration & dosage/*pharmacology; Inbred C57BL; 3; Intraperitoneal; 1-Methyl-4-phenyl-1; 2; Administration; Intranasal; 6-tetrahydropyridine/administration & dosage/*pharmacology
Creator
An entity primarily responsible for making the resource
Dluzen D E; Kefalas G
Description
An account of the resource
Male C57/B1 mice received bilateral intranasal infusions of saline, MPTP or an intraperitoneal injection of MPTP. Infusions were performed using a peristaltic pump at a setting of 100 microliters/min. The MPTP, diluted in saline at concentrations of 2 mg/ml, was infused over 15 (0.1 mg) or 30 (0.2 mg) s, while the saline (control) infusions were of 30 s duration. In a separate group of mice, MPTP was injected via the intraperitoneal route at a dose equivalent to that of the 30-s intranasal concentration (0.2 mg). At 7 days post-treatment, catecholamine concentrations were determined from the olfactory bulbs and corpus striatum. Concentrations of norepinephrine within both the olfactory bulbs and corpus striatum of mice receiving the intranasal infusion of MPTP were significantly lower than those of the intranasal saline and intraperitoneal
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1-Methyl-4-phenyl-1
1996
2
3
6-tetrahydropyridine/administration & dosage/*pharmacology
Administration
Animals
Brain research
Catecholamines/*metabolism
Corpus Striatum/drug effects/*metabolism
Department of Internal Medicine
Dluzen D E
Dopamine Agents/administration & dosage/*pharmacology
Dopamine/metabolism
Inbred C57BL
Injections
Intranasal
Intraperitoneal
Kefalas G
Male
Mice
NEOMED College of Medicine
Norepinephrine/metabolism
Olfactory Bulb/drug effects/*metabolism