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Text
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URL Address
<a href="http://doi.org/10.1089/lap.2021.0285" target="_blank" rel="noreferrer noopener">http://doi.org/10.1089/lap.2021.0285</a>
ISSN
1557-9034
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<a href="http://neomed.idm.oclc.org/login?url=http://doi.org/10.1089/lap.2021.0285" target="_blank" rel="noreferrer noopener">NEOMED Full-text Holding (if available) - Proxy DOI: 10.1089/lap.2021.0285</a>
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Update Year & Number
August 2021 List
NEOMED Department
NEOMED Student Publications
Dublin Core
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Title
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Managing Complex Perianal Fistulizing Disease.
Publisher
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Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Date
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2021
2021-07-27
Subject
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Crohn's disease; MANAGEMENT; QUALITY-OF-LIFE; cell therapy; ileostomy; perianal fistula; proctectomy; ANAL FISTULA; CLINICAL-TRIAL; DOUBLE-BLIND; FECAL DIVERSION; IN-ANO; REFRACTORY CROHNS-DISEASE; STEM-CELLS; SURGICAL-TREATMENT
Creator
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Pedersen KE; Lightner AL
Description
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Perianal disease is a particularly morbid phenotype of Crohn's disease, affecting up to one third of patients, with a significantly diminished quality of life. Conventional medical therapy and surgical interventions have limited efficacy. Medical treatment options achieve long-term durable remission in only a third of patients. Therefore, most patients undergo an operation, leaving them with a chronic seton or at risk of incontinence with multiple interventions. Mesenchymal stem cell therapy is an emerging therapy without risk of incontinence and improved efficacy as compared with conventional therapy. Laser therapy is another new intervention. Unfortunately, up to 40% of patients still require a stoma related to perianal fistulizing disease.
Identifier
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<a href="http://doi.org/10.1089/lap.2021.0285" target="_blank" rel="noreferrer noopener">10.1089/lap.2021.0285</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
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journalArticle
2021
ANAL FISTULA
August 2021 List
Cell therapy
clinical-trial
Crohn's disease
double-blind
FECAL DIVERSION
ileostomy
IN-ANO
Journal of laparoendoscopic & advanced surgical techniques. Part A
journalArticle
Lightner AL
Management
NEOMED College of Medicine Student
NEOMED Student Publications
Pedersen KE
perianal fistula
proctectomy
quality-of-life
REFRACTORY CROHNS-DISEASE
stem-cells
surgical-treatment