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              <text>https://doi.org/10.1016/j.jemermed.2021.11.022</text>
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                <text>Acute Cholecystitis With Situs Inversus Totalis</text>
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. 2022 Mar;62(3):e77-e79. doi: 10.1016/j.jemermed.2021.11.022. Epub 2022 Jan 20.</text>
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                <text>Calciphylaxis is a deadly disease that is currently diagnosed through a skin biopsy of resultant necrotic lesions despite many cases lacking this characteristic  finding. Recently, research has demonstrated the ability of various radiologic  techniques to detect calciphylaxis and have promoted their capabilities in earlier  diagnosis without tissue invasion. In this case, an obese 55-year-old female with  end stage renal disease, and a long history of dialysis, complained of weeks of  persistent abdominal pain that was accompanied by a mottled, lacey, net-like rash  that resembled livedo reticularis. Computed tomography of the abdomen revealed  extensive arterial calcification and subcutaneous calcium deposition. These  radiologic findings, coupled to a high clinical suspicion, prompted treatment for  suspected calciphylaxis. Remarkably, after 1 week the patient reported substantial  improvement. Hopefully, this publication in conjunction with previous and future  research will raise awareness on the role Radiologists can play in expediting the  diagnostic process for a lethal disease, especially when a tissue biopsy is not a  feasible option.</text>
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