1 40 1 Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. URL Address <a href="http://doi.org/10.3109/09546634.2011.643221" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/09546634.2011.643221</a> Pages 26–34 Issue 1 Volume 23 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A fixed-dose combination of adapalene 0.1%-BPO 2.5% allows an early and sustained improvement in quality of life and patient treatment satisfaction in severe acne. Publisher An entity responsible for making the resource available The Journal of dermatological treatment Date A point or period of time associated with an event in the lifecycle of the resource 2012 2012-02 Subject The topic of the resource Adult; Female; Humans; Male; Adolescent; Young Adult; Child; Severity of Illness Index; Quality of Life/*psychology; Double-Blind Method; *Patient Satisfaction; Drug Combinations; Acne Vulgaris/*drug therapy/*psychology; Adapalene; Benzoyl Peroxide/administration & dosage/*therapeutic use; Dermatologic Agents/administration & dosage/*therapeutic use; Naphthalenes/administration & dosage/*therapeutic use Creator An entity primarily responsible for making the resource Brodell Robert T; Schlosser Bethanee J; Rafal Elyse; Toth Darryl; Tyring Stephen; Wertheimer Albert; Kerrouche Nabil; Bucher Delphine Description An account of the resource INTRODUCTION: Acne has a significant negative impact on quality of life (QoL): lack of self-confidence, depressive symptoms and suicidal thoughts. The objective was to assess the impact of an initial and continued therapy in severe acne patients through patient-related outcomes (PRO). METHODS: In two sequential double-blind randomized studies, patients received either adapalene 0.1% and benzoyl peroxide 2.5% (A-BPO) or vehicle, associated with doxycycline 100 mg for 12 weeks. Patients having obtained at least a good improvement according to investigator global assessment were re-randomized for a 24-week therapy with Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.3109/09546634.2011.643221" target="_blank" rel="noreferrer noopener">10.3109/09546634.2011.643221</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s). *Patient Satisfaction 2012 Acne Vulgaris/*drug therapy/*psychology Adapalene Adolescent Adult Benzoyl Peroxide/administration & dosage/*therapeutic use Brodell Robert T Bucher Delphine Child Dermatologic Agents/administration & dosage/*therapeutic use Double-Blind Method Drug Combinations Female Humans Kerrouche Nabil Male Naphthalenes/administration & dosage/*therapeutic use Quality of Life/*psychology Rafal Elyse Schlosser Bethanee J Severity of Illness Index The Journal of dermatological treatment Toth Darryl Tyring Stephen Wertheimer Albert Young Adult