Basal cell adenocarcinoma of minor salivary glands.
Adenocarcinoma/*diagnosis/radiotherapy/surgery; Adenoid Cystic/diagnosis; Adenoma/diagnosis; Carcinoma; Combined Modality Therapy; Diagnosis; Differential; Humans; Minor/*pathology/surgery; Salivary Gland Neoplasms/*diagnosis/radiotherapy/surgery; Salivary Glands; Squamous Cell/diagnosis
Basal cell adenocarcinoma of minor salivary glands is a relatively rare slow-growing tumor with an infiltrating growth pattern. The infiltrating growth pattern and likelihood of vascular and perineural involvement distinguishes basal cell adenocarcinoma from basal cell adenoma. Other diagnostic considerations include adenoid cystic carcinoma and basaloid squamous carcinoma. Basal cell adenocarcinomas show strong immunoreactivity to cytokeratin 7 and variable myoepithelial staining with S100. It is necessary to differentiate basal cell adenocarcinoma from other basaloid cell tumors of the minor salivary glands because of the prognosis and potential differences in treatment, particularly adenoid cystic adenocarcinoma and basaloid squamous carcinoma. Surgical excision with a wide margin to ensure complete removal has been suggested as the primary treatment for basal cell adenocarcinoma. Radiotherapy has been proposed for lesions in the minor salivary glands because of the higher likelihood of vascular and neural invasion and for those that are diffusely infiltrative.
Farrell Tisha; Chang Yilan L
Archives of Pathology & Laboratory Medicine
2007
2007-10
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1043/1543-2165(2007)131%5B1602:BCAOMS%5D2.0.CO;2" target="_blank" rel="noreferrer noopener">10.1043/1543-2165(2007)131%5B1602:BCAOMS%5D2.0.CO;2</a>
Functioning liver metastases on an I-131 whole-body scan: a case of malignant struma ovarii.
*Iodine Radioisotopes; *Radiopharmaceuticals; *Whole-Body Irradiation; Adenoma/diagnosis; Female; Humans; Liver Neoplasms/diagnostic imaging/*secondary; Middle Aged; Multiple Primary/diagnosis; Neoplasms; Ovarian Neoplasms/*diagnostic imaging; Radionuclide Imaging; Struma Ovarii/diagnostic imaging/*secondary; Thyroid Neoplasms/diagnosis
A 46-year-old women was examined for severe constipation. Pelvic examination revealed a large pelvic mass extending to the level of the umbilicus. Computed tomography showed a large multicystic, septated mass in the pelvis and a small amount of fluid in the cul de sac. In addition, multiple ill-defined, mixed-attenuation hepatic lesions were identified. A malignant ovarian neoplasm with liver metastases was considered, so the pelvic mass was resected. Interestingly, histopathologic analysis revealed malignant struma ovarii of the follicular type. Biopsy of the liver lesions confirmed metastatic disease with similar histopathologic findings. All thyroid laboratory values were in the normal range. The patient then had a total thyroidectomy to optimize thyroid ablation therapy with I-131. This revealed a small follicular adenoma but no evidence of cancer. An I-131 whole-body scan was performed and showed uptake in multiple functioning liver metastases.
Konez O; Hanelin L G; Jenison E L; Goyal M; Randolph W
Clinical nuclear medicine
2000
2000-06
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
<a href="http://doi.org/10.1097/00003072-200006000-00014" target="_blank" rel="noreferrer noopener">10.1097/00003072-200006000-00014</a>