1
40
2
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Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1080/15476278.2016.1197461" target="_blank" rel="noreferrer noopener">http://doi.org/10.1080/15476278.2016.1197461</a>
Pages
119–127
Issue
3
Volume
12
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Current challenges in dedifferentiated fat cells research.
Publisher
An entity responsible for making the resource available
Organogenesis
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-07
Subject
The topic of the resource
*adult stem cells; *Biomedical Research; *Cell Dedifferentiation; *culture purity; *dedifferentiated fat cells; *dedifferentiation; *surface marker; Adipocytes/*cytology; Animals; Cells; Cultured; Humans; Phenotype
Creator
An entity primarily responsible for making the resource
Shah Mickey; George Richard L; Evancho-Chapman M Michelle; Zhang Ge
Description
An account of the resource
Dedifferentiated fat cells show great promises as a novel cell source for stem cell research. It has many advantages when used for cell-based therapeutics including abundance, pluripotency, and safety. However, there are many obstacles researchers need to overcome to make the next big move in DFAT cells research. In this review, we summarize the current main challenges in DFAT cells research including cell culture purity, phenotypic properties, and dedifferentiation mechanisms. The common methods to produce DFAT cells as well as the cell purity issue during DFAT cell production have been introduced. Current approaches to improve DFAT cell purity have been discussed. The phenotypic profile of DFAT cells have been listed and compared with other stem cells. Further studies on elucidating the underlying dedifferentiation mechanisms will dramatically advance DFAT cell research.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1080/15476278.2016.1197461" target="_blank" rel="noreferrer noopener">10.1080/15476278.2016.1197461</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*adult stem cells
*Biomedical Research
*Cell Dedifferentiation
*culture purity
*dedifferentiated fat cells
*dedifferentiation
*surface marker
2016
Adipocytes/*cytology
Animals
Cells
Cultured
Evancho-Chapman M Michelle
George Richard L
Humans
Organogenesis
Phenotype
Shah Mickey
Zhang Ge
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ar.23125" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ar.23125</a>
Pages
1416–1423
Issue
8
Volume
298
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Seasonal and Ontogenetic Variation in Subcutaneous Adipose Of the Bowhead Whale (Balaena mysticetus).
Publisher
An entity responsible for making the resource available
Anatomical record (Hoboken, N.J. : 2007)
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
2015-08
Subject
The topic of the resource
*Biological Evolution; *Seasons; Adaptation; Adipocytes/*cytology; adipose; Age Factors; Animals; Autopsy; blubber; bowhead; Bowhead Whale/*anatomy & histology/psychology; Cell Size; Feeding Behavior; Female; Male; ontogeny; Physiological; seasonal variation; Subcutaneous Fat/*cytology
Creator
An entity primarily responsible for making the resource
Ball Hope C; Stavarz Madeline; Oldaker Jonathan; Usip Sharon; Londraville Richard L; George John C; Thewissen Johnannes G M; Duff Robert Joel
Description
An account of the resource
Cetacean evolution was shaped by an extraordinary land-to-sea transition in which the ancestors of whales became fully aquatic. As part of this transition, these mammals evolved unusually thick blubber which acts as a metabolic reservoir as well as an insulator and provides buoyancy and streamlining. This study describes blubber stratification and correlates it to seasonal variation, feeding patterns, and ontogeny in an arctic-adapted mysticete, the bowhead whale (Balaena mysticetus). Bowheads are unique among mammals for possessing the largest known blubber stores. We found that adipocyte numbers in bowheads, like other mammals, do not vary with season or feeding pattern but that adipocyte size and structural fiber densities do vary with blubber depth.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ar.23125" target="_blank" rel="noreferrer noopener">10.1002/ar.23125</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Biological Evolution
*Seasons
2015
Adaptation
Adipocytes/*cytology
adipose
Age Factors
Anatomical record (Hoboken, N.J. : 2007)
Animals
Autopsy
Ball Hope C
Blubber
bowhead
Bowhead Whale/*anatomy & histology/psychology
Cell Size
Department of Anatomy & Neurobiology
Duff Robert Joel
Feeding Behavior
Female
George John C
Londraville Richard L
Male
NEOMED College of Medicine
Oldaker Jonathan
ontogeny
Physiological
seasonal variation
Stavarz Madeline
Subcutaneous Fat/*cytology
Thewissen Johnannes G M
Usip Sharon