Browse Items · NEOMED Bibliography Database

Accuracy and efficacy of nuclear scintigraphy for the detection of gastrointestinal bleeding.

OBJECTIVES: To determine the accuracy and cost-effectiveness of nuclear scintigraphy for the diagnosis and localization of gastrointestinal (GI) bleeding and to determine whether nuclear scintigraphy accurately predicts the results of angiography.…

Tags: 1997, 80 and over, Abdu R A, Adult, Aged, Archives of surgery (Chicago, Ill. : 1960), Garofalo T E, Gastrointestinal Hemorrhage/*diagnostic imaging, Humans, Middle Aged, Predictive Value of Tests, Radionuclide Imaging, Reproducibility of Results, Retrospective Studies

Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011.

IMPORTANCE: The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal of reducing inappropriate outpatient antibiotic use by 50% by 2020, but the extent of inappropriate outpatient antibiotic use is unknown. OBJECTIVE: To…

Tags: 2016, Adolescence, Adolescent, Adult, Aged, Ambulatory Care – Statistics and Numerical Data, Ambulatory Care/*statistics & numerical data, Anti-Bacterial Agents/*therapeutic use, Antibiotics – Therapeutic Use, Bartoces Monina, Child, Department of Internal Medicine, Enns Eva A, Female, File Thomas M Jr, Finkelstein Jonathan A, Fleming-Dutra Katherine E, Gerber Jeffrey S, Health Care Surveys, Hersh Adam L, Hicks Lauri A, Human, Humans, Hyun David Y, Inappropriate Prescribing – Statistics and Numerical Data, Inappropriate Prescribing/*statistics & numerical data, Infant, JAMA, Linder Jeffrey A, Lynfield Ruth, Male, Margolis David J, May Larissa S, Merenstein Daniel, Metlay Joshua P, Middle Age, Middle Aged, NEOMED College of Medicine, Newborn, Newland Jason G, Otitis Media, Otitis Media – Drug Therapy, Pharyngitis – Drug Therapy, Pharyngitis/drug therapy, Physicians'/*statistics & numerical data, Piccirillo Jay F, Practice Patterns, Preschool, Prevalence, Respiratory Tract Infections – Drug Therapy, Respiratory Tract Infections/drug therapy, Roberts Rebecca M, Sanchez Guillermo V, Shapiro Daniel J, Suda Katie J, Suppurative/*drug therapy, Surveys, Thomas Ann, United States, Woo Teri Moser, Zetts Rachel M

Ultrastructural aspects of human gallbladder epithelial cells in cholelithiasis: production of anionic mucus.

The surface epithelium of 28 gallbladders removed during elective cholecystectomies and pathology collection was studied ultrastructurally. Focusing on 10 of the 28 cases that were diagnosed as cholecystitis, we found that the epithelium displayed…

Sonographic appearance of the Angelchik prosthesis.

The Angelchik prosthesis is a silicone-filled, doughnut-shaped device used for the surgical treatment of gastroesophageal reflux. This device appears on sonograms as a C-shaped, hypoechoic structure with nonspecific Doppler waveforms. Because the…

Age-related size reduction of foramina in the cribriform plate.

Anecdotal evidence suggests that the foramina of the cribriform plate which transmit cranial nerve I decrease in size with age, but this finding has never been supported with quantitative data. It has also been observed that olfactory function…

Survey of cadaveric donors to a body donation program: 1978-1993.

Body donation files from the Department of Anatomy at Northeastern Ohio Universities College of Medicine were reviewed from the 569 donors used in our program from 1978-1993. The data were entered into a computerized database to evaluate the…

Survey of cadaveric donor application files: 1978-1993.

Information derived from application files of potential cadaveric donors to our body donation program from the period of 1978-1993 was entered into a customized database to assess the characteristics of people contributing to such a program. A total…

Antigenic stimulation and multiple myeloma. A prospective study.

BACKGROUND: A causal relationship between antigenic conditions and multiple myeloma was suggested by case reports. Although controlled studies identified associations with individual conditions, they failed to give overall support to the hypothesis.…

A comparison of the full and short versions of the Arthritis Impact Measurement Scales.

This study examined the validity and reliability of full and short versions of the Arthritis Impact Measurement Scales (AIMS). One hundred fifty-five patients with Rheumatoid Arthritis followed at a University Hospital Rheumatology Clinic completed…

Tags: *Disability Evaluation, *Severity of Illness Index, 1991, Abraham N, Activities of Daily Living, Adult, Aged, Alarcon G S, Arthritis, Arthritis care and research : the official journal of the Arthritis Health Professions Association, Austin J S, Bradley L A, Female, Humans, Lorish C D, Male, Middle Aged, Reproducibility of Results, Rheumatoid/*diagnosis/rehabilitation

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.

OBJECTIVE: Hedgehog (HH) signaling has recently been associated with cartilage degradation in osteoarthritis (OA). Because interleukin-1beta (IL-1beta) has been implicated as a principal instigator of OA, we sought to determine whether

Tags: 2015, Academic Medical Centers, Aged, Akhtar Nahid, Analysis of Variance, Animal, Animals, Anterior Cruciate Ligament/surgery, Arthritis & rheumatology (Hoboken, N.J.), Blotting, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism/pathology, Cultured, Department of Anatomy & Neurobiology, Disease Models, Female, Funding Source, Gene Expression Regulation/genetics/*physiology, Haqqi Tariq M, Hedgehog Proteins/genetics/*metabolism, HEK293 Cells, Human, Humans, Immunohistochemistry, In Vitro Techniques, Interleukin-1beta/pharmacology, Knee/etiology/*metabolism/pathology, Makki Mohammad S, Male, Matrix Metalloproteinase 13/metabolism, MicroRNAs/genetics/*metabolism, Middle Age, Middle Aged, NEOMED College of Medicine, Ohio, Open Reading Frames/genetics/*physiology, Osteoarthritis, Osteoarthritis – Epidemiology, Osteoarthritis – Physiopathology, Polymerase Chain Reaction, Rabbits, Signal Transduction/genetics/physiology, T-Tests, Transfection, Up-Regulation/drug effects/genetics/physiology, Western

MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1beta-stimulated human chondrocytes.

OBJECTIVE: Enhanced expression of interleukin-6 (IL-6) plays an important role in the pathogenesis of osteoarthritis (OA). Monocyte chemoattractant protein-induced protein 1 (MCPIP-1) is a novel posttranscriptional regulator of IL-6 expression and is…

Tags: 2015, Academic Medical Centers, Aged, Arthritis & rheumatology (Hoboken, N.J.), Articular/drug effects/*metabolism, Cartilage, Cells, Chondrocytes – Physiology, Chondrocytes/drug effects/*metabolism, Cultured, Department of Anatomy & Neurobiology, Enzyme-Linked Immunosorbent Assay, Funding Source, Gene Knockdown Techniques, Haqqi Tariq M, Haseeb Abdul, Hip/*genetics/metabolism, Human, Humans, Immunoblotting – Utilization, Immunoprecipitation, Interleukin-1beta/pharmacology, Interleukin-6/*genetics/metabolism, Interleukins – Physiology, Makki Mohammad S, Messenger/drug effects/*metabolism, MicroRNAs/drug effects/*genetics/metabolism, Middle Aged, NEOMED College of Medicine, Ohio, Osteoarthritis, Osteoarthritis – Complications, Osteoarthritis – Physiopathology, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleases/drug effects/*genetics/metabolism, RNA, T-Tests, Transcription Factors/drug effects/*genetics/metabolism

Phase II study of gefitinib in patients with advanced salivary gland cancers.

BACKGROUND: The purpose of this study was to determine the antitumor activity of the epidermal growth factor receptor (EGFR) inhibitor gefitinib in patients with recurrent/metastatic salivary gland cancer. METHODS: We conducted a phase II study in…

Tags: 2015, 80 and over, Adenocarcinoma/drug therapy/mortality/pathology, adenoid cystic carcinoma, Adenoid Cystic/*drug therapy/mortality/pathology, Adult, Aged, Antineoplastic Agents/*therapeutic use, Blumenschein George R Jr, Carcinoma, Department of Internal Medicine, Disease-Free Survival, Dose-Response Relationship, Drug, Drug Administration Schedule, El-Naggar Adel K, Female, Gefitinib, Glisson Bonnie S, Gonzalez-Angulo Ana M, Head & neck, Humans, Jakob John A, Kies Merrill S, Kupferman Michael E, Lee J Jack, Liu Diane D, Local/*drug therapy/mortality/pathology, Male, Maximum Tolerated Dose, Middle Aged, NEOMED College of Medicine, Neoplasm Invasiveness/pathology, Neoplasm Recurrence, Neoplasm Staging, non-adenoid cystic carcinoma, Prognosis, Quinazolines/*therapeutic use, Remission Induction, response to therapy, salivary gland cancer, Salivary Gland Neoplasms/*drug therapy/mortality/pathology, Survival Analysis, Treatment Outcome

Vocal cord paralysis from prostatic carcinoma metastasizing to the larynx.

According to 1992 Cancer Statistics, prostate carcinoma is once again predicted to be the most common cancer in men, exceeding the incidence of lung cancer. In American men, this cancer is estimated to be the second most frequent cause of cancer…

Tags: 1993, Adenocarcinoma/*pathology/*secondary, Aged, Head & neck, Humans, Laryngeal Neoplasms/*secondary, Male, Park M H, Park Y W, Prostatic Neoplasms/*pathology, Thyroid Cartilage/pathology, Vocal Cord Paralysis/*etiology

Evaluation of indicated non-cosmetic panniculectomy at time of gynecologic surgery.

OBJECTIVE: To report postoperative outcomes among patients undergoing indicated non-cosmetic panniculectomy at the time of gynecologic surgery. METHODS: Medical charts were retrospectively reviewed for patients who underwent panniculectomy coupled…

Tags: *Abdominoplasty/adverse effects, *Gynecologic Surgical Procedures/adverse effects, 2017, 80 and over, Abdominal/*surgery, Abdominoplasty – Adverse Effects, Adipose Tissue – Surgery, Adult, Aged, Body Mass Index, Female, Female – Complications, Female – Surgery, Female/complications/*surgery, Genital Diseases, Gynecologic – Adverse Effects, Gynecologic surgery, Hopkins Michael P, Humans, Infection, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, Middle Age, Middle Aged, Obesity, Obesity – Complications, Obesity – Surgery, Obesity/complications/*surgery, Panniculectomy, Patibandla Jay R, Rasmussen Ryan W, Retrospective Design, Retrospective Studies, Risk Factors, Subcutaneous Fat, Surgery, Surgical Wound Infection – Etiology, Surgical Wound Infection/*etiology, Wound complication, Wound Healing

Sucrose, But Not Glucose, Blocks IL1-beta-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.

Pathogenesis of osteoarthritis (OA) is multifactorial but interleukin-1beta (IL-1beta) is known to be an important mediator of cartilage degradation. Autophagy is an essential cellular homeostasis mechanism and has been proposed to protect against…

Quantitative skin assessment using spatial frequency domain imaging (SFDI) in patients with or at high risk for pressure ulcers.

BACKGROUND AND OBJECTIVE: Pressure ulcers (PU) are a significant problem facing the health system in the United States. Here, we present preliminary case studies demonstrating feasibility of Spatial Frequency Domain Imaging (SFDI) to assess skin…

Gender differences in the association between antidepressant use and restless legs syndrome.

Contradictory results have been reported for the association between antidepressant use and Restless Legs Syndrome (RLS). Our aim was to clarify the relationship and examine possible gender differences. We interviewed 1,693 veterans receiving primary…

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

What happens when effective outpatient civil commitment is terminated?

Outpatient civil commitment can be effective in slowing the revolving door for selected patients, but it may not be the best mechanism for ensuring treatment over time.

Metastatic carcinoma of the spine with neurologic complications: an autopsy review.

We conducted post-mortem examinations on 12 patients who had documented metastatic carcinoma to the spine with attendant neurologic complications. The examinations were studied to determine the location of the metastatic lesion in relation to the…

Tags: 1993, Adult, Aged, Autopsy, Female, Humans, Leeson M C, Male, Middle Aged, Orthopedics, Spinal Cord Compression/*etiology/pathology, Spinal Neoplasms/*complications/pathology/*secondary, Zechmann J P

Laparoscopic hernia repair. Three-year experience.

The basis of laparoscopic transabdominal preperitoneal repair (LTPR) of herniae rests upon the utilization of a prosthetic screen to cover hernia defects. Preperitoneal prosthetic screen interposition reproduces the effect of the inguinal shutter…

Tags: 1995, 80 and over, Adolescent, Adult, Aged, Female, Follow-Up Studies, Hernia, Humans, Inguinal/*surgery, Kavic M S, Laparoscopy/*methods, Male, Middle Aged, Postoperative Complications, Prostheses and Implants, Reoperation, Surgical endoscopy

Recognition of depression by internal medicine residents.

We studied the ability of internal medicine residents to recognize depressive symptoms in a population of lower socio-economic primary care patients. Four hundred twenty patients completed the short form of the Beck Depression Inventory (BDI).…

Adenocarcinoma arising in interposed colon: report of a case.

A rare occurrence of primary adenocarcinoma arising in an interposed colon nearly seven years after the surgery is described. Remarkably, there were no symptoms from a large mass in the transposed bowel. Diagnosis was made fortuitously while…

Rectal trauma and associated hemorrhage with the use of the ConvaTec Flexi-Seal fecal management system: report of 3 cases.

The management of fecal incontinence is a struggle to maintain patient hygiene and limit the transmission of nosocomial infections. Intrarectal devices that cause diversion and collection of the fecal stream have been used with increasing frequency.…

Tags: 2010, Aged, Catheterization/*adverse effects/*instrumentation, Chase Daniel, Coughlin Lisa, Diseases of the colon and rectum, Fecal Incontinence/*therapy, Female, Gastrointestinal Hemorrhage/*etiology/surgery, Heaton Bren, Hemostasis, Humans, Male, Metha Jeet, Middle Aged, Pressure Ulcer/*etiology/surgery, Rectum/*injuries/surgery, Sparks Dorothy, Surgical/methods

Appendicitis in the elderly: a change in the laparoscopic era.

BACKGROUND: Appendicitis in elderly patients is associated with significant morbidity and mortality. Early and correct diagnosis together with minimally invasive surgery can lead to more favorable outcomes than occurred in the prelaparoscopic era.…

Revisiting classification of pain from bone metastases as mild, moderate, or severe based on correlation with function and quality of life.

PURPOSE: The objective of our study was to determine the optimal cut points for classification of pain scores as mild, moderate, and severe based on interference with function and quality of life (QOL). METHODS: We evaluated 822 patients who…

Tags: *Quality of Life, *Severity of Illness Index, 2016, 80 and over, Adolescence, Adolescent, Adult, Aged, Babington Scott, Bone metastases, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms/*complications/secondary, Brief pain inventory, Brundage Michael, Chow Edward, Demas William F, Ding Keyue, Female, Functional interference, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, Ong Francisca, Pain – Classification, Pain – Etiology, Pain Measurement – Methods, Pain Measurement/*methods, Pain severity, Pain/*classification/etiology, Parulekar Wendy R, Quality of Life, Questionnaires, Re-irradiation, Roos Daniel, Severity of Illness Indices, Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, Survival, van der Linden Yvette M, van Tienhoven Geertjan, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Young Adult, Zhu Liting

Identification of plasma microRNA expression profile in radiographic axial spondyloarthritis-a pilot study.

At present, there are no studies that have established a microRNA (miRNA)-based signature profile in patients with radiographic axial spondyloarthritis (rad-axial SpA), and we hypothesized that these patients may have aberrantly expressed circulating…

Splenic rupture following colonoscopy: two cases with CT findings.

Splenic injury following colonoscopy is extremely rare. We report a 75-year-old woman and a 35-year-old woman who presented to the emergency room with left upper quadrant and left shoulder pain following colonoscopy. Both patients were diagnosed by…

Tags: *Tomography, 2006, Abdominal Pain/diagnostic imaging/etiology, Adult, Aged, Colonoscopy/*adverse effects, Edwards D Makana, Emergency radiology, Female, Hemoperitoneum/diagnostic imaging/etiology/surgery, Hemorrhage/diagnostic imaging/etiology/surgery, Humans, Johnson Craig, Mader Michael, Shoulder Pain/diagnostic imaging/etiology, Splenectomy, Splenic Rupture/*diagnostic imaging/*etiology/surgery, Vesy Thomas, X-Ray Computed

Caudate body (CB) sign: new early CT sign of hyperacute anterior cerebral circulation infarction.

This case series describes the caudate body (CB) sign noted in computed tomography (CT) scans of patients who presented to the Emergency Department (ED) clinically manifesting symptoms suggestive of anterior cerebral circulation infarction. This sign…

Tags: *Tomography, 2011, 80 and over, Aged, Ahmed Shamima Y, Basal Ganglia – Pathology, Brain Infarction/*diagnostic imaging, Caudate Nucleus/*pathology, Emergency Medicine, Emergency radiology, Female, Humans, Infarction – Radiography, Khalaf Hamzah Suhail, Kurman Andrew J, Male, Tomography, X-Ray Computed, Young Adult

Lacking a Primary Care Physician Is Associated With Increased Suffering in Patients With Severe Mental Illness.

We evaluated the relationship between lack of a primary care physician (PCP) and patients with severe mental illness (SMI), who have poorer health and experience more suffering. Using a blinded retrospective record review of 137 patients with SMI,…

Tags: *Health Services Accessibility, *Primary Health Care, 2017, Adolescence, Adolescent, Adult, Aged, Amerine Jenna, Boltri John M, Clasen Mark E, Community, Comorbid conditions, Cost of Illness, Department of Family & Community Medicine, Economic Aspects of Illness, Female, Health outcomes, Health Services Accessibility, Hospitalization, Hospitals, Humans, Life Style, Lifestyle problems, Male, Mental Disorders – Complications, Mental Disorders – Psychosocial Factors, Mental Disorders – Therapy, Mental Disorders/complications/*psychology/*therapy, Middle Age, Middle Aged, NEOMED College of Medicine, Olsen Cynthia G, Preventative services, Primary Health Care, Psychological – Etiology, Psychological – Psychosocial Factors, Psychological/etiology/*psychology, Retrospective Design, Retrospective Studies, Stress, The journal of primary prevention, Young Adult

Is mortality due to primary malignant brain and other central nervous system tumors decreasing?

Primary malignant brain and other central nervous system tumors (BT) are a rare cancer that causes morbidity and mortality disproportionate to their incidence. This study presents the most up-to-date mortality data for malignant BT in the United…

Estimating the annual frequency of synchronous brain metastasis in the United States 2010-2013: a population-based study.

Brain metastases (BM) are one of the most common types of brain tumors and are a relatively common event in the disease process for several high-incidence cancer types, including breast and lung cancers. Historically, information on metastases…

Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases.

PURPOSE: The EORTC QLQ-C30 and the Brief Pain Inventory (BPI) are validated tools for measuring quality of life (QOL) and the impact of pain in patients with advanced cancer. Interpretation of these instrument scores can be challenging and it is…

Tags: *Bone metastases, *Brief pain inventory, *EORTC QLQ-C30, *Minimal Clinically Important Difference, *Minimal clinically important differences, *Radiation, 2018, 80 and over, Adolescence, Adolescent, Adult, Aged, Babington Scott, Bone Metastases – Radiotherapy, BONE metastasis, BONE metastasis – Treatment, Bone Neoplasms/*complications/radiotherapy/secondary, Brief pain inventory, Brundage Michael, Cancer Patients, CANCER radiotherapy, Chow Edward, Clinical Assessment Tools, Demas William F, Ding Keyue, Female, Funding Source, Haas Rick, Hartsell William F, Hoskin Peter, Human, Humans, Instrument Scaling, LONGITUDINAL method, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, Pain Management, Pain/*diagnosis, Prospective Studies, Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, Quality of Life/*psychology, Questionnaires, Raman Srinivas, RANDOMIZED controlled trials, Re-Irradiation/*adverse effects, Reoperation, Repeat Procedures, RESEARCH funding, Roos Daniel, SCALING (Social sciences), Secondary Analysis, Surveys and Questionnaires, van der Linden Yvette M, Wiggenraad Ruud, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Young Adult, Zhu Liting

Group A streptococcus necrotizing fasciitis.

Necrotizing fasciitis due to Group A streptococcus has been observed with increasing frequency over the past decade. Appropriate management requires rapid recognition of this life-threatening infection and expeditious antimicrobial therapy as well as…

Renal Cell Carcinoma Metastatic to the Gallbladder.

Tags: 2018, Aged, Carcinoma, Cholecystectomy, Cocieru Andrei, Deeken Amy, Female, Gallbladder Neoplasms/diagnostic imaging/pathology/*secondary/surgery, Gallbladder/diagnostic imaging/pathology/surgery, Hazen Ben, Humans, Journal of gastrointestinal cancer, Kidney Neoplasms/diagnostic imaging/*pathology, Renal Cell/diagnostic imaging/pathology/*secondary/surgery, Tomography, X-Ray Computed

Non-health Care Facility Medication Errors Associated with Hormones and Hormone Antagonists in the United States.

INTRODUCTION: Hormones and hormone antagonists are frequently associated with medication errors and may result in important adverse outcomes. The purpose of this study is to investigate non-health care facility (non-HCF) medication errors associated…

Home modification to prevent falls by older ED patients.

This trial was conducted at 11 EDs to test the effectiveness of distributing fall prevention information to patients 65 years or older. Intervention patients were given 2 brochures and received a reminder call 2 weeks later. All patients were called…

Tags: 2005, Accidental Falls/*prevention & control, Accidents, Aged, Camargo Carlos A Jr, Female, Gerson Lowell W, Home/*prevention & control, Humans, Male, Prospective Studies, Safety, The American journal of emergency medicine, Wilber Scott T

A comparison of implanted cardioverter/defibrillator interrogation protocol effectiveness between 2 patients in the ED.

Weakness and fatigue in older ED patients in the United States.

BACKGROUND: The objectives of this study are to estimate the prevalence of weakness and fatigue visits in older emergency department (ED) patients, to compare demographics and resource use in these patients with those without these complaints, and to…

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