1
40
1
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1161/STROKEAHA.116.013513" target="_blank" rel="noreferrer noopener">http://doi.org/10.1161/STROKEAHA.116.013513</a>
Pages
2286–2291
Issue
9
Volume
47
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept-The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial.
Publisher
An entity responsible for making the resource available
Stroke
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-09
Subject
The topic of the resource
*cerebral cortex; *infarction; *stroke; *tissue; Angiography; Brain; Brain Ischemia/*diagnostic imaging/therapy; Brain/*diagnostic imaging; Capillaries; Capillaries/*diagnostic imaging; Cerebral Ischemia; Cerebral Ischemia – Therapy; Checklists; Comparative Studies; Computed Tomography Angiography/*methods; Digital Subtraction – Methods; Digital Subtraction/*methods; Endovascular Procedures/methods; Evaluation Research; Human; Humans; Multicenter Studies; Randomized Controlled Trials; Scales; Stroke; Stroke – Therapy; Stroke/*diagnostic imaging/therapy; Treatment Outcome; Treatment Outcomes; Validation Studies
Creator
An entity primarily responsible for making the resource
Al-Ali Firas; Berkhemer Olvert A; Yousman Wina P; Elias John J; Bender Evin N; Lingsma Hester F; van der Lugt Aad; Dippel Diederik W J; Roos Yvo B W E M; van Oostenbrugge Robert J; van Zwam Wim H; Dillon William P; Majoie Charles B L M
Description
An account of the resource
BACKGROUND AND PURPOSE: The capillary index score (CIS) is based on the hypothesis that areas lacking capillary blush on pretreatment cerebral digital subtraction angiograms correspond to nonviable cerebral tissue. METHODS: Pretreatment digital subtraction angiograms and post-treatment noncontrast enhanced computed tomographic scans from the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) trial were evaluated for areas lacking capillary blush and with tissue hypodensity, respectively. Because the superior and middle zones of the CIS correspond to the 7 cerebral cortex regions of the Alberta Stroke Program Early CT (ASPECT) score, capillary blush was scored in these 2 zones (0-2), called sub-CIS, and compared with the ASPECT score in these 7 regions (0-7), called hypodensity score. The presence and extent of hypodensity were compared between sub-CIS zones with contingency tables and nonparametric comparisons between groups, respectively. RESULTS: On the basis of a sample size of 50 subjects, 100% with sub-CIS \textless2 had the presence of hypodensity (hypodensity score \textgreater/=1) versus 57% for sub-CIS=2 (P=0.004). The extent of hypodensity (numeric hypodensity score) was significantly lower for sub-CIS=2 than 0 or 1 (P=0.02). For 42 subjects with revascularization data, the presence and extent of hypodensity were significantly lower for sub-CIS=2 plus good revascularization than for other combinations of sub-CIS and revascularization (P=0.02 and 0.01, respectively). CONCLUSIONS: The absence of capillary blush on pretreatment digital subtraction angiogram seems to correspond to nonviable cerebral tissue. Successful revascularization reduces the chance of tissue hypodensity (infarction), when capillary blush is present. CLINICAL TRIAL REGISTRATION: URL: http://www.trialregister.nl. Unique identifier: NTR number 1804. URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1161/STROKEAHA.116.013513" target="_blank" rel="noreferrer noopener">10.1161/STROKEAHA.116.013513</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*cerebral cortex
*infarction
*stroke
*tissue
2016
Al-Ali Firas
Angiography
Bender Evin N
Berkhemer Olvert A
Brain
Brain Ischemia/*diagnostic imaging/therapy
Brain/*diagnostic imaging
Capillaries
Capillaries/*diagnostic imaging
Cerebral Ischemia
Cerebral Ischemia – Therapy
Checklists
Comparative Studies
Computed Tomography Angiography/*methods
Digital Subtraction – Methods
Digital Subtraction/*methods
Dillon William P
Dippel Diederik W J
Elias John J
Endovascular Procedures/methods
Evaluation Research
Human
Humans
Lingsma Hester F
Majoie Charles B L M
Multicenter Studies
RANDOMIZED controlled trials
Roos Yvo B W E M
Scales
stroke
Stroke – Therapy
Stroke/*diagnostic imaging/therapy
Treatment Outcome
Treatment Outcomes
Validation Studies
van der Lugt Aad
van Oostenbrugge Robert J
van Zwam Wim H
Yousman Wina P