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Tags: Amines/*pharmacology

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Stabilization of clathrin coated vesicles by amantadine, tromantadine and other hydrophobic amines.

Amantadine and related compounds stabilized the structure of purified pig brain clathrin coated vesicles (CCV) at biologically relevant concentrations. Incubation of purified CCV for 30 min at 25 degrees C or 37 degrees C caused the release of…

Tags: 1991, Amantadine/*analogs & derivatives/*pharmacology, Amines/*pharmacology, Animals, Brain/metabolism, Cell-Membrane/drug effects/*metabolism, Clathrin/*metabolism, Coated Pits, FEBS letters, Kinetics, Phonphok Y, Rosenthal K S, Structure-Activity Relationship, Swine

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