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40
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Text
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Pages
4–20
Volume
17
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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From mechanisms to management: translating the neuropathic pain consensus recommendations into clinical practice.
Publisher
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Journal of the American Academy of Nurse Practitioners
Date
A point or period of time associated with an event in the lifecycle of the resource
2005
2005-06-02
Subject
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Adult; Female; Aged; Inflammation; Pain Measurement; Comorbidity; Education; Neoplasm Metastasis; Drugs; Perception; Clinical Trials; Middle Age; Sarcoidosis; Analgesics; Drug Therapy; Combination; Antidepressive Agents; Treatment Outcomes; Cancer Patients; Chronic Pain; Treatment Duration; Breast Neoplasms; Visual Analog Scaling; Lung Neoplasms; Melanoma; Rectal Neoplasms; Continuing (Credit); Transdermal Patches; Lidocaine – Administration and Dosage; Analgesics – Administration and Dosage; Analgesics – Adverse Effects; Cytokines – Physiology; Gabapentin – Administration and Dosage; Neural Transmission – Physiology; Neuralgia – Classification; Neuralgia – Drug Therapy; Neuralgia – Physiopathology; Opioid – Administration and Dosage; Peripheral Nervous System – Physiopathology; Tramadol – Administration and Dosage; Tricyclic – Administration and Dosage
Creator
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Chevlen E; Davies PS; Rhiner M
Description
An account of the resource
Chronic neuropathic pain poses a treatment challenge, and is associated with significant psychologic distress, physical disability, and impaired functioning, which impact the activities of daily living. Efforts to provide relief are often inadequate and/or require polypharmacy. This has spurred interest among researchers and clinicians alike to develop early, intensive treatments that target the molecular and cellular mechanisms involved in pain transduction, transmission, and modulation, or ideally, that prevent neuropathic pain from occurring in the first place. Currently, researchers are attempting to capitalize on our understanding of neuropathic pain pathophysiology to develop drugs that interrupt distinct activities involved in its perpetuation. In this regard, several potential agents (eg, NMDA and AMPA/kainate antagonists) are in phase 2 and 3 clinical trials. In the interim, evolving data and evidence-based neuropathic treatment recommendations provide guidance for selecting first- and second-line medications that alone or in combination offer acceptable neuropathic pain control and allow clinicians to bridge the gap between current knowledge and its application in the clinical setting. Hopefully, as basic and clinical science progresses, further treatment advances and management tools will be found to improve the care of patients who live with neuropathic pain.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2005
Adult
Aged
Analgesics
Analgesics – Administration and Dosage
Analgesics – Adverse Effects
Antidepressive Agents
Breast Neoplasms
Cancer Patients
Chevlen E
Chronic pain
Clinical Trials
Combination
Comorbidity
Continuing (Credit)
Cytokines – Physiology
Davies PS
Department of Internal Medicine
Drug Therapy
Drugs
Education
Female
Gabapentin – Administration and Dosage
Inflammation
Journal of the American Academy of Nurse Practitioners
Lidocaine – Administration and Dosage
Lung Neoplasms
Melanoma
Middle Age
NEOMED College of Medicine
Neoplasm Metastasis
Neural Transmission – Physiology
Neuralgia – Classification
Neuralgia – Drug Therapy
Neuralgia – Physiopathology
Opioid – Administration and Dosage
Pain Measurement
Perception
Peripheral Nervous System – Physiopathology
Rectal Neoplasms
Rhiner M
Sarcoidosis
Tramadol – Administration and Dosage
Transdermal Patches
Treatment Duration
Treatment Outcomes
Tricyclic – Administration and Dosage
Visual Analog Scaling