1
40
14
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.1983.tb18129.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.1983.tb18129.x</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
388-390
Volume
421
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Tumor-inhibition By Human Alpha-2-macroglobulin
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1983
1983
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
Koo P H
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.1983.tb18129.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.1983.tb18129.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1983
Annals of the New York Academy of Sciences
Journal Article or Conference Abstract Publication
Koo P H
Science & Technology - Other Topics
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
613-615
Volume
575
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Hypothalamic Alpha-2-noradrenergic Receptor System - Relation To Dietary, Genetic, And Hormonally Induced Obesity
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1989
1989-12
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
Jhanwaruniyal M; Grinker J A; Finkelstein J A; Block W; Leibowitz S F
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1989
Annals of the New York Academy of Sciences
Block W
Finkelstein J A
Grinker J A
Jhanwaruniyal M
Journal Article or Conference Abstract Publication
Leibowitz S F
Science & Technology - Other Topics
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.1982.tb21476.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.1982.tb21476.x</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
546-548
Volume
386
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Alterations In Hamster Uterine Catalase Levels As A Result Of Estrogen-treatment - A Histoenzymatic Analysis
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1982
1982
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Steggles A W
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.1982.tb21476.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.1982.tb21476.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1982
Annals of the New York Academy of Sciences
Gilloteaux J
Science & Technology - Other Topics
Steggles A W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.1990.tb13237.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.1990.tb13237.x</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
373-376
Volume
588
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Endocardial Surface Changes During Hamster Atrium Development - A Tem, Sem, And Anf Immunoelectron Microscopic Study
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1990
1990-04
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
Gilloteaux J; Linz D
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.1990.tb13237.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.1990.tb13237.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
1990
Annals of the New York Academy of Sciences
Gilloteaux J
Linz D
Science & Technology - Other Topics
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.1990.tb48992.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.1990.tb48992.x</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
480-482
Volume
611
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Dublin Core
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Title
A name given to the resource
HYPOTHALAMIC NEUROPEPTIDE-Y EXPRESSION IN NORMAL AND ABERRANT METABOLIC HOMEOSTASIS
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1990
1990-11
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
White J D; Kershaw M; Sanacora G; Olchovsky D; Finkelstein J A; Berelowitz M
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.1990.tb48992.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.1990.tb48992.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1990
Annals of the New York Academy of Sciences
Berelowitz M
Finkelstein J A
Journal Article
Kershaw M
Olchovsky D
Sanacora G
Science & Technology - Other Topics
White J D
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.1991.tb33911.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.1991.tb33911.x</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
757-759
Volume
625
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
ORDERING AND SOLUBILITY OF ALKANES AND ALKANOLS IN PHOSPHOLIPID-BILAYERS - A H-2-NMR STUDY OF THE CUTOFF EFFECT
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-06
Subject
The topic of the resource
Science & Technology - Other Topics
Creator
An entity primarily responsible for making the resource
Westerman P W; Pope J M
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.1991.tb33911.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.1991.tb33911.x</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article
1991
Annals of the New York Academy of Sciences
Journal Article
Pope J M
Science & Technology - Other Topics
Westerman P W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
757–759
Volume
625
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Ordering and solubility of alkanes and alkanols in phospholipid bilayers: a
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991
Subject
The topic of the resource
Structure-Activity Relationship; Solubility; Deuterium; *Lipid Bilayers; Alcohols/*chemistry; Alkanes/*chemistry; Cholesterol/chemistry; Magnetic Resonance Spectroscopy/methods; Phosphatidylcholines/*chemistry
Creator
An entity primarily responsible for making the resource
Westerman P W; Pope J M
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Lipid Bilayers
1991
Alcohols/*chemistry
Alkanes/*chemistry
Annals of the New York Academy of Sciences
Cholesterol/chemistry
Deuterium
Magnetic Resonance Spectroscopy/methods
Phosphatidylcholines/*chemistry
Pope J M
Solubility
Structure-Activity Relationship
Westerman P W
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
460–464
Volume
737
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Monoamine-activated alpha 2-macroglobulin inhibits neurite outgrowth, survival, choline acetyltransferase, and dopamine concentration of neurons by blocking neurotrophin-receptor (trk) phosphorylation and signal transduction.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-09
Subject
The topic of the resource
Humans; Animals; Cell Survival/drug effects; Phosphorylation/drug effects; Signal Transduction/*drug effects; Infant; Neurons/physiology; Rats; Species Specificity; Choline O-Acetyltransferase/metabolism; Dopamine/metabolism; alpha-Macroglobulins/*pharmacology; Biogenic Monoamines/*pharmacology; Neurites/physiology; Prosencephalon/cytology/*physiology; Receptor Protein-Tyrosine Kinases/*drug effects; Newborn; Receptors; Nerve Growth Factor/*drug effects
Creator
An entity primarily responsible for making the resource
Koo P H; Liebl D J; Qiu W S; Hu Y Q; Dluzen D E
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
alpha-Macroglobulins/*pharmacology
Animals
Annals of the New York Academy of Sciences
Biogenic Monoamines/*pharmacology
Cell Survival/drug effects
Choline O-Acetyltransferase/metabolism
Dluzen D E
Dopamine/metabolism
Hu Y Q
Humans
Infant
Koo P H
Liebl D J
Nerve Growth Factor/*drug effects
Neurites/physiology
Neurons/physiology
Newborn
Phosphorylation/drug effects
Prosencephalon/cytology/*physiology
Qiu W S
Rats
Receptor Protein-Tyrosine Kinases/*drug effects
Receptors
Signal Transduction/*drug effects
Species Specificity
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1196/annals.1432.010" target="_blank" rel="noreferrer noopener">http://doi.org/10.1196/annals.1432.010</a>
Pages
140–150
Volume
1139
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sex differences in dopamine- and vesicular monoamine-transporter functions.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2008
2008-10
Subject
The topic of the resource
3; 4-Dihydroxyphenylacetic Acid/metabolism; Adrenergic Uptake Inhibitors/metabolism; Animal/drug effects; Animals; Behavior; Behavior/drug effects; Corpus Striatum/metabolism; Dopamine Agents/pharmacology; Dopamine Plasma Membrane Transport Proteins/*metabolism; Dopamine Uptake Inhibitors/metabolism; Female; Humans; Male; Methamphetamine/pharmacology; Mice; Nomifensine/metabolism; Reserpine/metabolism; Sex Factors; Vesicular Monoamine Transport Proteins/*metabolism
Creator
An entity primarily responsible for making the resource
Dluzen D E; McDermott J L
Description
An account of the resource
Men and women differ with regard to their use of, and responses to, methamphetamine (MA). Analogous sex differences with regard to MA are observed in animal models. In this report, data from a series of experiments that focus upon dopamine transporter (DAT) and vesicular monoamine transporter2 (VMAT2) function are reviewed by way of providing some understanding for these sex differences to MA. The amount of dopamine (DA) recovered after infusion of DA into superfused striatal tissue was greater in females and an accentuated amount of extracellular DA was obtained from females after infusion of the DAT-blocking drug, nomifensine. These data suggest a higher level of DAT activity in females. To evaluate the implications of this sex difference in DAT function as related to MA, the amount of DA evoked by an infusion of MA into superfused striatal tissue was tested and found to be significantly greater in males. In contrast, potassium chloride-stimulated DA release was greater in females. The results of these
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1196/annals.1432.010" target="_blank" rel="noreferrer noopener">10.1196/annals.1432.010</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2008
3
4-Dihydroxyphenylacetic Acid/metabolism
Adrenergic Uptake Inhibitors/metabolism
Animal/drug effects
Animals
Annals of the New York Academy of Sciences
Behavior
Behavior/drug effects
Corpus Striatum/metabolism
Dluzen D E
Dopamine Agents/pharmacology
Dopamine Plasma Membrane Transport Proteins/*metabolism
Dopamine Uptake Inhibitors/metabolism
Female
Humans
Male
McDermott J L
Methamphetamine/pharmacology
Mice
Nomifensine/metabolism
Reserpine/metabolism
Sex Factors
Vesicular Monoamine Transport Proteins/*metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1196/annals.1369.025" target="_blank" rel="noreferrer noopener">http://doi.org/10.1196/annals.1369.025</a>
Pages
282–294
Volume
1074
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Estrogen, testosterone, and methamphetamine toxicity.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2006
2006-08
Subject
The topic of the resource
Animals; Corpus Striatum/drug effects/metabolism; Dopamine Agents/*administration & dosage/toxicity; Drug Interactions; Estrogens/*pharmacology; Female; Male; Methamphetamine/*administration & dosage/toxicity; Mice; Testosterone/*pharmacology
Creator
An entity primarily responsible for making the resource
Dluzen Dean E; McDermott Janet L
Description
An account of the resource
The gonadal steroid hormone, estrogen, can diminish the degree of striatal dopamine depletion resulting from methamphetamine. In this article, we describe the conditions of this estrogen neuroprotection as well as the potential for estrogen and testosterone to enhance methamphetamine-induced neurodegeneration of the nigrostriatal dopaminergic system. When administered prior to a neurotoxic regimen of methamphetamine, estrogen significantly decreases the amount of striatal dopamine depletion in intact or gonadectomized female, but not male, mice. This capacity for estrogen to function as a neuroprotectant can occur quite rapidly, at 30 min prior to methamphetamine administration, and with relatively low doses of estrogen (1 microg estradiol benzoate). Estrogen remains an effective neuroprotectant in neonatally gonadectomized female mice treated with testosterone, but not in female mice that were gonadectomized prior to puberty. Nor does estrogen demonstrate any beneficial effects when administered after methamphetamine. Recent data have indicated some conditions where gonadal steroids can increase the extent of striatal neurodegeneration in response to methamphetamine. Specifically, when some existing perturbation is present in the nigrostriatal dopaminergic system, treatment with estrogen enhances the extent of striatal dopamine depletion to methamphetamine. Similarly, increased striatal dopamine depletion to methamphetamine is observed in gonadectomized male mice treated with testosterone.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1196/annals.1369.025" target="_blank" rel="noreferrer noopener">10.1196/annals.1369.025</a>
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Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2006
Animals
Annals of the New York Academy of Sciences
Corpus Striatum/drug effects/metabolism
Dluzen Dean E
Dopamine Agents/*administration & dosage/toxicity
Drug Interactions
Estrogens/*pharmacology
Female
Male
McDermott Janet L
Methamphetamine/*administration & dosage/toxicity
Mice
Testosterone/*pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1196/annals.1316.026" target="_blank" rel="noreferrer noopener">http://doi.org/10.1196/annals.1316.026</a>
Pages
205–220
Volume
1025
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Developmental and genetic influences upon gender differences in methamphetamine-induced nigrostriatal dopaminergic neurotoxicity.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2004
2004-10
Subject
The topic of the resource
*Sex Characteristics; Animals; Corpus Striatum/*drug effects/growth & development/metabolism; Dopamine/*metabolism; Female; Humans; Male; Methamphetamine/*toxicity; Substantia Nigra/*drug effects/growth & development/metabolism
Creator
An entity primarily responsible for making the resource
Dluzen Dean E; McDermott Janet L
Description
An account of the resource
The gonadal steroid hormone estrogen (E) may play an important role in sex differences in methamphetamine (MA)-induced neurotoxicity of the nigrostriatal dopaminergic (NSDA) system because E can serve as a neuroprotectant in female, but not male, mice. Gonadal steroid hormones also exert important organizational/developmental effects upon the brain at critical developmental periods. In Part 1 we assessed whether organizational (neonatal) or developmental (prepubertal) effects of gonadal steroids would alter gender/E-dependent neuroprotection of MA-induced NSDA neurotoxicity. Attempts to feminize male mice by gonadectomy at either the neonatal or prepubertal period failed to enable E to function as a neuroprotectant within the adult male mouse. Attempts to masculinize the female by testosterone administration at the neonatal period did not abolish the capacity for E to function as a neuroprotectant. However, prepubertal gonadectomy of female mice did disrupt E's capacity to serve as a neuroprotectant. These results suggest that genetic sex may prove the primary determinant for the sex differences observed in response to MA-induced NSDA neurotoxicity. In Part 2 we examined whether gender differences in response to
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1196/annals.1316.026" target="_blank" rel="noreferrer noopener">10.1196/annals.1316.026</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Sex Characteristics
2004
Animals
Annals of the New York Academy of Sciences
Corpus Striatum/*drug effects/growth & development/metabolism
Dluzen Dean E
Dopamine/*metabolism
Female
Humans
Male
McDermott Janet L
Methamphetamine/*toxicity
Substantia Nigra/*drug effects/growth & development/metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/nyas.13156" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/nyas.13156</a>
Pages
80–86
Issue
1
Volume
1378
Dublin Core
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Title
A name given to the resource
Novel approaches to mitigating parathion toxicity: targeting cytochrome
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-08
Subject
The topic of the resource
*menadione; *organophosphorus pesticides; *paraoxon; *parathion; *redox cycling; Animals; Cholinesterase Inhibitors/metabolism/*toxicity; Cytochrome P-450 Enzyme Inhibitors/*administration & dosage/metabolism; Cytochrome P-450 Enzyme System/metabolism; Drug Delivery Systems/*methods; Humans; Insecticides/metabolism/toxicity; Organophosphate Poisoning/drug therapy/enzymology; Parathion/metabolism/*toxicity; Vitamin K 3/*administration & dosage/metabolism
Creator
An entity primarily responsible for making the resource
Jan Yi-Hua; Richardson Jason R; Baker Angela A; Mishin Vladimir; Heck Diane E; Laskin Debra L; Laskin Jeffrey D
Description
An account of the resource
Accidental or intentional exposures to parathion, an organophosphorus (OP) pesticide, can cause severe poisoning in humans. Parathion toxicity is dependent on its metabolism by the cytochrome P450 (CYP) system to paraoxon (diethyl
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/nyas.13156" target="_blank" rel="noreferrer noopener">10.1111/nyas.13156</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*menadione
*organophosphorus pesticides
*paraoxon
*parathion
*redox cycling
2016
Animals
Annals of the New York Academy of Sciences
Baker Angela A
Cholinesterase Inhibitors/metabolism/*toxicity
Cytochrome P-450 Enzyme Inhibitors/*administration & dosage/metabolism
Cytochrome P-450 Enzyme System/metabolism
Department of Pharmaceutical Sciences
Drug Delivery Systems/*methods
Heck Diane E
Humans
Insecticides/metabolism/toxicity
Jan Yi-Hua
Laskin Debra L
Laskin Jeffrey D
Mishin Vladimir
NEOMED College of Pharmacy
Organophosphate Poisoning/drug therapy/enzymology
Parathion/metabolism/*toxicity
Richardson Jason R
Vitamin K 3/*administration & dosage/metabolism
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.2002.tb04157.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.2002.tb04157.x</a>
Pages
136–156
Volume
965
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Estrogen, anti-estrogen, and gender: differences in methamphetamine neurotoxicity.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
2002-06
Subject
The topic of the resource
*Neurotoxins; *Sex Characteristics; Animals; Biological; Estrogen Antagonists/*pharmacology; Estrogens/*physiology; Female; Humans; Male; Methamphetamine/*toxicity; Mice; Models; Tamoxifen/pharmacology; Testosterone/pharmacology
Creator
An entity primarily responsible for making the resource
Dluzen Dean E; McDermott Janet L
Description
An account of the resource
In Part 1 of this report, we review data on the effects of estrogen (E), the anti-E tamoxifen (TMX), and testosterone (T) on methamphetamine (METH)-induced neurotoxicity in female and male CD-1 mice. Treatment of gonadectomized females with a physiological regimen of E significantly diminished the amount of striatal dopamine (DA) depletion to METH compared with non-E-treated mice. If these
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.2002.tb04157.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.2002.tb04157.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Neurotoxins
*Sex Characteristics
2002
Animals
Annals of the New York Academy of Sciences
Biological
Dluzen Dean E
Estrogen Antagonists/*pharmacology
Estrogens/*physiology
Female
Humans
Male
McDermott Janet L
Methamphetamine/*toxicity
Mice
Models
Tamoxifen/pharmacology
Testosterone/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1111/j.1749-6632.2000.tb05189.x" target="_blank" rel="noreferrer noopener">http://doi.org/10.1111/j.1749-6632.2000.tb05189.x</a>
Pages
112–126
Volume
914
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Neuroprotective role of estrogen upon methamphetamine and related neurotoxins within the nigrostriatal dopaminergic system.
Publisher
An entity responsible for making the resource available
Annals of the New York Academy of Sciences
Date
A point or period of time associated with an event in the lifecycle of the resource
2000
2000-09
Subject
The topic of the resource
Animals; Corpus Striatum/*drug effects/metabolism; Dopamine/*metabolism; Drug Interactions; Estrogens/*administration & dosage; Methamphetamine/antagonists & inhibitors/*toxicity; Neurotoxins/antagonists & inhibitors/*toxicity; Substantia Nigra/*drug effects/metabolism; Time Factors
Creator
An entity primarily responsible for making the resource
Dluzen D E; McDermott J L
Description
An account of the resource
In this report we describe some of the data on the capacity for estrogen to function as a neuroprotectant of the nigrostriatal dopaminergic (NSDA) system. The data show that estrogen (E) can alter two different response characteristics to NSDA neurotoxins. The first being that striatal DA concentrations of ovariectomized rodents treated with E are consistently greater than non-E-treated animals in response to neurotoxins which produce degeneration of the NSDA system. The second being that E significantly reduces the amount of DA output upon initial exposure to the NSDA neurotoxin, 1-methyl-4-phenylpyridium ion (MPP+). At present, it is not known whether these two response characteristics are related. An intriguing possibility is that the E-dependent changes in initial DA output are related to the resultant neurotoxicity (attenuations in DA concentration reductions). So far our incipient findings do not seem to support this eventuality. However, additional testing on this topic is required. The present data suggest that one of the mechanisms by which E can exert these effects is through inhibition of DAT activity. This conclusion results from data which show that E produces: 1) an inhibition of [3H]DA uptake, 2) a reduction in DA clearance rates, and 3) an effect upon DA recovery that is similar to that observed to the putative DA uptake blocker, nomifensine. The capacity and significance for steroid hormones to modulate neurotransmitter transporters has been recently reviewed.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1111/j.1749-6632.2000.tb05189.x" target="_blank" rel="noreferrer noopener">10.1111/j.1749-6632.2000.tb05189.x</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2000
Animals
Annals of the New York Academy of Sciences
Corpus Striatum/*drug effects/metabolism
Dluzen D E
Dopamine/*metabolism
Drug Interactions
Estrogens/*administration & dosage
McDermott J L
Methamphetamine/antagonists & inhibitors/*toxicity
Neurotoxins/antagonists & inhibitors/*toxicity
Substantia Nigra/*drug effects/metabolism
Time Factors