Browse Items · NEOMED Bibliography Database

Ambulatory management of lower respiratory tract infections.

Clinical manifestations and radiographic findings are unreliable guides to the selection of antimicrobial therapy for lower respiratory infections. Laboratory evaluation is necessary to identify the etiologic agent. Multiple oral antibiotics are…

Tags: 1991, American family physician, Anti-Bacterial Agents/*therapeutic use, Bacterial Infections/drug therapy, Department of Internal Medicine, File T M Jr, Humans, Legionnaires' Disease/diagnosis, Mycoplasma/diagnosis, NEOMED College of Medicine, Pneumonia, Pneumonia/*diagnosis/*drug therapy, Tan J S, Thomson R B Jr

Approaches to Modifying the Behavior of Clinicians Who Are Noncompliant With Antimicrobial Stewardship Program Guidelines.

Antimicrobial stewardship programs (ASPs) are a key national initiative to promote appropriate use of antibiotics and to reduce the burden of resistance. The dilemma of managing the outlier physician is especially complex. We outline strategies to…

Assessment of time to clinical response, a proxy for discharge readiness, among hospitalized patients with community-acquired pneumonia who received either ceftaroline fosamil or ceftriaxone in two phase III FOCUS trials.

The primary driver of health care costs for patients with community-acquired pneumonia (CAP) is the hospital length of stay (LOS). Unfortunately, hospital LOS comparisons are difficult to make from phase III CAP trials because of their structured…

Case studies of lower respiratory tract infections: community-acquired pneumonia.

Community-acquired pneumonia (CAP) is a common and potentially serious illness with significant human and economic costs to society. The recent collaborative statement from the Infectious Diseases Society of America (IDSA) and the American Thoracic…

Tags: 2010, Acute – Microbiology, Adult, Adult/microbiology, Aged, Anti-Bacterial Agents/*therapeutic use, Antibiotics – Therapeutic Use, Antitubercular Agents – Therapeutic Use, Antitubercular Agents/therapeutic use, Community-Acquired Infections – Diagnosis, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections/diagnosis/drug therapy, Cough, Cough – Microbiology, Cough/microbiology/virology, Department of Internal Medicine, Diagnosis, Differential, Dyspnea, Fatal Outcome, Female, Fever – Microbiology, Fever/microbiology, File Thomas M Jr, Hemoptysis – Microbiology, Hemoptysis/microbiology, Human, Human – Complications, Human – Diagnosis, Human/complications/*diagnosis, Humans, Hypotension – Microbiology, Hypotension/microbiology, Influenza, Leukopenia – Microbiology, Leukopenia/microbiology, Male, Methicillin-Resistant Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus/*isolation & purification, Miliary/diagnosis/drug therapy, Multiple Organ Dysfunction Syndrome – Microbiology, Multiple Organ Failure/microbiology, Mycobacterium Tuberculosis, Mycobacterium tuberculosis/isolation & purification, NEOMED College of Medicine, Pneumonia – Diagnosis, Pneumonia – Drug Therapy, Pneumonia – Microbiology, Pneumonia – Therapy, Pneumonia/*diagnosis/*drug therapy/microbiology/therapy, Practice Guidelines, Practice Guidelines as Topic, Respiratory Distress Syndrome, Risk Factors, Severity of Illness Index, Severity of Illness Indices, Smoking, Smoking/adverse effects, Staphylococcal Infections – Diagnosis, Staphylococcal Infections – Drug Therapy, Staphylococcal Infections – Microbiology, Staphylococcal Infections – Therapy, Staphylococcal Infections/*diagnosis/*drug therapy/microbiology/therapy, The American journal of medicine, Tuberculosis, Tuberculosis – Diagnosis, Tuberculosis – Drug Therapy

Ceftaroline fosamil versus ceftriaxone for the treatment of community-acquired pneumonia: individual patient data meta-analysis of randomized controlled trials.

BACKGROUND: We conducted a meta-analysis of clinical trials of adults hospitalized with pneumonia outcomes research team (PORT) risk class 3-4 community-acquired pneumonia (CAP) receiving ceftaroline fosamil versus ceftriaxone. METHODS: Three Phase…

Cutaneous abscesses in children: epidemiology in the era of methicillin-resistant Staphylococcus aureus in a pediatric emergency department.

OBJECTIVE: Skin and soft tissue infections are a major public health issue. Previous literature suggests a recurrence rate of 4% in children. The purpose of this study was to examine the epidemiology, body location, and history of previous infections…

Diagnosis and treatment of diabetic foot infections.

Prompt clinical diagnosis and timely treatment are the hallmarks of the proper care of diabetic patients with foot infections. The importance of careful clinical foot examination cannot be overemphasized. When infection is suspected, effort should be…

Tags: 1999, Anti-Bacterial Agents/*therapeutic use, Bacterial Infections/*diagnostic imaging/*drug therapy, Bailliere's best practice & research. Clinical rheumatology, Department of Internal Medicine, Diabetic Foot/*microbiology, File T M Jr, Humans, NEOMED College of Medicine, Radiography, Tan J S

Does empiric therapy for atypical pathogens improve outcomes for patients with CAP?

The present controversy regarding the need to cover atypical pathogens in the empiric therapy of community-acquired pneumonia is related to several issues, including the relevance of terminology, imprecise diagnostic methods, and perceived…

Tags: 2013, Anti-Bacterial Agents/*therapeutic use, Antibiotic Prophylaxis, Antibiotics – Therapeutic Use, Clinical Trials, Clinical Trials as Topic, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections – Microbiology, Community-Acquired Infections/drug therapy/microbiology, Department of Internal Medicine, File Thomas M Jr, Humans, Infectious disease clinics of North America, Marrie Thomas J, NEOMED College of Medicine, Pneumonia – Drug Therapy, Pneumonia – Microbiology, Pneumonia/*drug therapy/microbiology

Effect of a standardized pharyngitis treatment protocol on use of antibiotics in a pediatric emergency department.

BACKGROUND: Pharyngitis is a common complaint in pediatric patients. If clinical parameters are used alone, bacterial pathogens will be wrongly implicated in many cases. A nonstandardized approach to the treatment of children with pharyngitis in an…

Hemipelvic amputations for recalcitrant pelvic osteomyelitis.

OBJECTIVE: To evaluate the outcome of recalcitrant deep pelvic infection that required a hemipelvic amputation. STUDY DESIGN: Retrospective cohort. SETTING: Tertiary referral centre; Level I trauma. PATIENTS: There were 20 patients with an infection…

Is combination therapy for carbapenem-resistant Klebsiella pneumoniae the new standard of care?

Carbapenem-resistant Klebsiella pneumoniae causes serious nosocomial infections and therapeutic options are limited. There is increasing evidence suggesting that combination antibiotic therapy is more effective than monotherapy and leads to better…

Tags: 2015, Anti-Bacterial Agents/*therapeutic use, beta-Lactam Resistance/genetics, carbapenem-resistant Klebsiella pneumoniae, Carbapenems/*therapeutic use, combination antibiotic therapy, Combination/*statistics & numerical data, Department of Internal Medicine, Deresinski Stan, Drug Therapy, Expert review of anti-infective therapy, Humans, Klebsiella Infections/*drug therapy/microbiology, Klebsiella pneumoniae/*drug effects/genetics/pathogenicity, NEOMED College of Medicine, Randomized Controlled Trials as Topic, Watkins Richard R

Limitations of the obstetric group B Streptococcus protocol.

OBJECTIVE: To assess compliance with the Centers for Disease Control and Prevention (CDC) screening-based protocol for obstetric group B Streptococcus (GBS) and to determine an acceptable threshold for protocol failure. STUDY DESIGN: A retrospective…

On the path to untreatable infections: colistin use in agriculture and the end of 'last resort' antibiotics.

Overview of resistance in the 1990s.

The tremendous therapeutic advantage afforded by antibiotics is being threatened by the emergence of increasingly resistant strains of microbes. Selective pressure favoring resistant strains arises from misuse and overuse of antimicrobials (notably…

Tags: *Drug Resistance, 1999, Anti-Bacterial Agents/*therapeutic use, Bacterial/*drug therapy, Chest, Community-Acquired Infections/drug therapy, Cross Infection/drug therapy, Department of Internal Medicine, File T M Jr, Humans, Multiple, NEOMED College of Medicine, Pneumonia

Predisposing factors and antibiotic use in nosocomial infections caused by Xanthomonas maltophilia.

Tags: *Xanthomonas/isolation & purification, 1992, Anti-Bacterial Agents/*therapeutic use, Cross Infection/*drug therapy/microbiology, Department of Internal Medicine, File T M, Gram-Negative Bacterial Infections/*drug therapy/microbiology, Hulisz D T, Humans, Infection control and hospital epidemiology, NEOMED College of Medicine, Risk Factors

Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011.

IMPORTANCE: The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal of reducing inappropriate outpatient antibiotic use by 50% by 2020, but the extent of inappropriate outpatient antibiotic use is unknown. OBJECTIVE: To…

Tags: 2016, Adolescence, Adolescent, Adult, Aged, Ambulatory Care – Statistics and Numerical Data, Ambulatory Care/*statistics & numerical data, Anti-Bacterial Agents/*therapeutic use, Antibiotics – Therapeutic Use, Bartoces Monina, Child, Department of Internal Medicine, Enns Eva A, Female, File Thomas M Jr, Finkelstein Jonathan A, Fleming-Dutra Katherine E, Gerber Jeffrey S, Health Care Surveys, Hersh Adam L, Hicks Lauri A, Human, Humans, Hyun David Y, Inappropriate Prescribing – Statistics and Numerical Data, Inappropriate Prescribing/*statistics & numerical data, Infant, JAMA, Linder Jeffrey A, Lynfield Ruth, Male, Margolis David J, May Larissa S, Merenstein Daniel, Metlay Joshua P, Middle Age, Middle Aged, NEOMED College of Medicine, Newborn, Newland Jason G, Otitis Media, Otitis Media – Drug Therapy, Pharyngitis – Drug Therapy, Pharyngitis/drug therapy, Physicians'/*statistics & numerical data, Piccirillo Jay F, Practice Patterns, Preschool, Prevalence, Respiratory Tract Infections – Drug Therapy, Respiratory Tract Infections/drug therapy, Roberts Rebecca M, Sanchez Guillermo V, Shapiro Daniel J, Suda Katie J, Suppurative/*drug therapy, Surveys, Thomas Ann, United States, Woo Teri Moser, Zetts Rachel M

Pylephlebitis: a case report and review of outcome in the antibiotic era.

Pylephlebitis or septic thrombophlebitis of the portal vein, a precursor of hepatic abscesses, is an extremely rare and frequently fatal complication of diverticulitis. The following report describes a patient presenting with pylephlebitis and…

Recommendations for treatment of hospital-acquired and ventilator-associated pneumonia: review of recent international guidelines.

Recently published guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia are reviewed for recommendations regarding diagnosis and antimicrobial therapy to assess the implications for development of future…

Tags: *Practice Guidelines as Topic, 2010, Anti-Bacterial Agents/*therapeutic use, Bacteria/drug effects/isolation & purification, Bacterial/diagnosis/*drug therapy, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Clinical Trials as Topic, Cross Infection/diagnosis/*drug therapy, Department of Internal Medicine, File Thomas M Jr, Hospitals, Humans, Microbial Sensitivity Tests, NEOMED College of Medicine, Pneumonia, Time Factors, Ventilator-Associated/diagnosis/*drug therapy

Solutions to the problem of bacterial resistance.

The recent increase in bacterial resistance has been, and continues to be, unmatched by drug discovery and development. The judicious use of antibacterials must be observed so as to contain bacterial resistance and maintain the utility of agents…

Tags: *Drug Resistance, *Practice Guidelines as Topic, 2005, Anti-Bacterial Agents/*therapeutic use, Bacterial, Department of Internal Medicine, Dose-Response Relationship, Drug, Drug Administration Schedule, Drug Prescriptions/standards, Drug Utilization, File Thomas M Jr, Humans, NEOMED College of Medicine, Professional Practice/*standards, Treatments in respiratory medicine, Unnecessary Procedures

The science of selecting antimicrobials for community-acquired pneumonia (CAP).

BACKGROUND: Among infectious diseases, community-acquired pneumonia (CAP) is the leading cause of death in the United States and is associated with a substantial economic burden to the health care system. Initiating appropriate empiric therapy can be…

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