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The goals of optimal antimicrobial therapy are to treat infection effectively, to improve the clinical condition of the patient, and to prevent the emergence of resistant bacterial strains. For ideal drug usage the World Health Organization…

An observational study from England showed that restricting fluoroquinolone use reduced incidence of Clostridium difficile infection more than would be predicted by improved infection control methods alone.

The author discusses the study which involved children aged six to twenty three months diagnosed with acute otitis media (AOM) basing on indications such as onset of symptoms in the preceding 48 hours, the presence of a middle-ear suffusion and…

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