1
40
3
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jtcvs.2016.03.046" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jtcvs.2016.03.046</a>
Pages
1618–1619
Issue
6
Volume
152
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Minocycline pigmentation of the cardiac valves and aorta in a 29-year survivor of liver transplant.
Publisher
An entity responsible for making the resource available
The Journal of thoracic and cardiovascular surgery
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-12
Subject
The topic of the resource
*Liver Transplantation; Adult; Anti-Bacterial Agents/*adverse effects; Aorta/*drug effects; Aortic Aneurysm/diagnosis/surgery; Heart Valve Prosthesis Implantation; Heart Valves/*drug effects; Humans; Incidental Findings; Male; Minocycline/*adverse effects; Pigmentation Disorders/*chemically induced; Survivors
Creator
An entity primarily responsible for making the resource
Cohen Maria A; Owens Scott R; Yang Bo
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.jtcvs.2016.03.046" target="_blank" rel="noreferrer noopener">10.1016/j.jtcvs.2016.03.046</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Liver Transplantation
2016
Adult
Anti-Bacterial Agents/*adverse effects
Aorta/*drug effects
Aortic Aneurysm/diagnosis/surgery
Cohen Maria A
Department of Family & Community Medicine
Heart Valve Prosthesis Implantation
Heart Valves/*drug effects
Humans
Incidental Findings
Male
Minocycline/*adverse effects
NEOMED College of Medicine
Owens Scott R
Pigmentation Disorders/*chemically induced
Survivors
The Journal of thoracic and cardiovascular surgery
Yang Bo
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1993.265.6.H2073" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1993.265.6.H2073</a>
Pages
H2073–2080
Issue
6
Volume
265
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Role of endothelium in sexual dimorphism in vasopressin-induced contraction of rat aorta.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1993
1993-12
Subject
The topic of the resource
*Sex Characteristics; *Vasoconstriction; Animals; Aorta/*drug effects; Arginine Vasopressin/*pharmacology; Arginine/analogs & derivatives/pharmacology; Endothelium; Female; Indomethacin/pharmacology; Male; Nitric Oxide/antagonists & inhibitors; omega-N-Methylarginine; Osmolar Concentration; Phenylephrine/pharmacology; Rats; Sprague-Dawley; Vascular/*physiology
Creator
An entity primarily responsible for making the resource
Stallone J N
Description
An account of the resource
In rat thoracic aorta, contractile responses to arginine vasopressin (AVP) are twofold higher in females than in males. To determine the role of the endothelium in this phenomenon, the effects of endothelium removal and inhibition of nitric oxide (NO) synthase and cyclooxygenase were examined in thoracic aortas prepared from male and female Sprague-Dawley rats and mounted for isometric tension recording. Maximal contractile response to AVP was substantially higher in female (4,232 +/- 316 mg/mg ring dry wt) than in male aortas (1,365 +/- 239; P \textless 0.01). Removal of the endothelium markedly potentiated maximal response to AVP in male aortas (4,100 +/- 422 mg/mg ring wt; P \textless 0.01); endothelium removal increased sensitivity but not maximal response in female aortas. Inhibition of NO synthase with NG-monomethyl-L-arginine (L-NMMA, 250 microM) doubled maximal contraction to AVP in male aortas (3,175 +/- 193 mg/mg ring wt; P \textless 0.01); L-NMMA increased sensitivity but not maximal response in female aortas. Inhibition of cyclooxygenase with indomethacin (10 microM) did not alter maximal response to AVP in male aortas but significantly attenuated responses of female aortas (2,816 +/- 306 mg/mg ring wt; P \textless 0.01). In contrast, maximal contractile response to phenylephrine hydrochloride (PE) was 40% higher in males than in females (P \textless 0.01); L-NMMA increased both the sensitivity and maximal response to PE to a greater extent in female (3,061 +/- 121 vs. 4,971 +/- 135 mg/mg ring wt; P \textless 0.01) than in male aortas (4,317 +/- 227 vs. 4,899 +/- 104 mg/mg ring wt; P \textless 0.01). (ABSTRACT TRUNCATED AT 250 WORDS)
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1993.265.6.H2073" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1993.265.6.H2073</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Sex Characteristics
*Vasoconstriction
1993
Animals
Aorta/*drug effects
Arginine Vasopressin/*pharmacology
Arginine/analogs & derivatives/pharmacology
Endothelium
Female
Indomethacin/pharmacology
Male
Nitric Oxide/antagonists & inhibitors
omega-N-Methylarginine
Osmolar Concentration
Phenylephrine/pharmacology
Rats
Sprague-Dawley
Stallone J N
The American journal of physiology
Vascular/*physiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1152/ajpheart.1991.260.2.H453" target="_blank" rel="noreferrer noopener">http://doi.org/10.1152/ajpheart.1991.260.2.H453</a>
Pages
H453–458
Issue
2
Volume
260
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Sexual dimorphism in vasopressin-induced contraction of rat aorta.
Publisher
An entity responsible for making the resource available
The American journal of physiology
Date
A point or period of time associated with an event in the lifecycle of the resource
1991
1991-02
Subject
The topic of the resource
*Sex Characteristics; *Vasoconstriction; Animals; Aorta/*drug effects; Arginine Vasopressin/*pharmacology; Dose-Response Relationship; Drug; Female; Male; Osmolar Concentration; Phenylephrine/pharmacology; Rats
Creator
An entity primarily responsible for making the resource
Stallone J N; Crofton J T; Share L
Description
An account of the resource
Previously, we reported that, in the rat, pressor responsiveness to vasopressin (VP) is higher in males than in females during most phases of the estrous cycle. To explore the role of the vasculature in this phenomenon, we examined vascular reactivity to VP in thoracic aortas of male rats and female rats during each phase of the estrous cycle. Aortic rings were prepared from age-matched male and female Sprague-Dawley rats and mounted for isometric tension recording. Maximal response of female aortas to VP (4,246 +/- 163 mg/mg ring dry wt) was more than twice (P less than 0.001) that of male aortas (1,877 +/- 215 mg/mg ring wt). Sensitivity of female aortas to VP was substantially higher (P less than 0.001) than that of male aortas (EC50: 10.9 +/- 0.7 vs. 19.0 +/- 1.6 nM, respectively). Maximal rate of tension development (dT/dtmax) during contraction with VP was nearly twofold higher (P less than 0.01) in female aortas (536 +/- 23 mg/min) than in male aortas (300 +/- 19 mg/min). Maximal response, sensitivity, and dT/dtmax of female aortas did not vary significantly during the estrous cycle. Maximal response of female aortas to phenylephrine (PE; 1,251 +/- 93 mg/mg ring wt) was half that (P less than 0.001) of male aortas (2,546 +/- 194 mg/mg ring wt); sensitivity to PE did not differ significantly (EC50: 0.33 +/- 0.02 vs. 0.38 +/- 0.06 microM, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1152/ajpheart.1991.260.2.H453" target="_blank" rel="noreferrer noopener">10.1152/ajpheart.1991.260.2.H453</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Sex Characteristics
*Vasoconstriction
1991
Animals
Aorta/*drug effects
Arginine Vasopressin/*pharmacology
Crofton J T
Dose-Response Relationship
Drug
Female
Male
Osmolar Concentration
Phenylephrine/pharmacology
Rats
Share L
Stallone J N
The American journal of physiology