1
40
2
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Text
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URL Address
<a href="http://doi.org/10.1007/s12029-016-9841-5" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s12029-016-9841-5</a>
Pages
379–381
Issue
4
Volume
48
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Gastrocolic Fistula as a Presentation of Concomitant Gastric and Colon Cancer in a Patient with a History of Metastatic Pancreatic Adenocarcinoma.
Publisher
An entity responsible for making the resource available
Journal of gastrointestinal cancer
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-12
Creator
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Nayfe Rabih; Ascha Mustafa S; Ismail Mayada; Salvino Richard
Identifier
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<a href="http://doi.org/10.1007/s12029-016-9841-5" target="_blank" rel="noreferrer noopener">10.1007/s12029-016-9841-5</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Ascha Mustafa S
Department of Internal Medicine
Ismail Mayada
Journal of gastrointestinal cancer
Nayfe Rabih
NEOMED College of Medicine
Salvino Richard
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.12659/AOT.909781" target="_blank" rel="noreferrer noopener">http://doi.org/10.12659/AOT.909781</a>
Pages
631–638
Volume
23
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Effect of Immunosuppressive Therapy on the Occurrence of Atypical Hemolytic Uremic Syndrome in Renal Transplant Recipients.
Publisher
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Annals of transplantation
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-09
Subject
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Adult; Female; Humans; Male; Middle Aged; Adrenal Cortex Hormones/adverse effects; Atypical Hemolytic Uremic Syndrome/*epidemiology/etiology; Immunosuppression/adverse effects; Immunosuppressive Agents/*adverse effects; Incidence; Kidney Transplantation/*adverse effects; Postoperative Complications/*epidemiology/etiology; Retrospective Studies; Sirolimus/adverse effects; Transplant Recipients; Kidney Failure; Chronic/*surgery
Creator
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Raina Rupesh; Chauvin Abigail; Fox Kelli; Kesav Natasha; Ascha Mustafa S; Vachharajani Tushar J; Krishnappa Vinod
Description
An account of the resource
BACKGROUND Atypical hemolytic uremic syndrome (aHUS), a rare thrombotic microangiopathy, is characterized by hemolytic anemia, thrombocytopenia, and acute renal failure. Caused by genetic mutations in the alternative complement cascade, aHUS often will culminate in end-stage renal disease and occasionally death. Renal transplantation in aHUS patients has been contraindicated in the past due to the recurrence risk, with certain immunosuppressive regimens being commonly attributed. In this study, we analyzed the association between aHUS and immunosuppressive agents so as to offer evidence for the use of certain immunosuppressive regimens in renal transplant recipients. MATERIAL AND METHODS Our study is a retrospective analysis using data from the United States Renal Data System from 2004 to 2012. A cohort of renal transplantation patients diagnosed with aHUS were identified to include in the study. The primary endpoint was the determination of aHUS incidence in renal transplant recipients due to various immunosuppressive agents. The secondary endpoints were to check the relationship between the drug type as well as the demographic variables that increase the risk for aHUS. RESULTS It was found that there was a higher usage of sirolimus (P=0.015) and corticosteroids (P=0.030) in the aHUS patients compared to patients in other diagnoses group. CONCLUSIONS There was a higher usage of sirolimus and corticosteroids in renal transplantation patients diagnosed with aHUS. Unfortunately, due to the rarity of this disease, the sample size was small (n=14). Despite the small sample size, this data analysis throws light on the relationship between aHUS and immunosuppressive agents in renal transplant recipients, although we still have much to learn.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.12659/AOT.909781" target="_blank" rel="noreferrer noopener">10.12659/AOT.909781</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Adrenal Cortex Hormones/adverse effects
Adult
Annals of transplantation
Ascha Mustafa S
Atypical Hemolytic Uremic Syndrome/*epidemiology/etiology
Chauvin Abigail
Chronic/*surgery
Department of Internal Medicine
Female
Fox Kelli
Humans
Immunosuppression/adverse effects
Immunosuppressive Agents/*adverse effects
Incidence
Kesav Natasha
Kidney Failure
Kidney Transplantation/*adverse effects
Krishnappa Vinod
Male
Middle Aged
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Postoperative Complications/*epidemiology/etiology
Raina Rupesh
Retrospective Studies
Sirolimus/adverse effects
Transplant Recipients
Vachharajani Tushar J