1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1186/s12891-016-0892-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1186/s12891-016-0892-3</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
14-14
Volume
17
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Growth And Repair Factors, Osteoactivin, Matrix Metalloproteinase And Heat Shock Protein 72, Increase With Resolution Of Inflammation In Musculotendinous Tissues In A Rat Model Of Repetitive Grasping
Publisher
An entity responsible for making the resource available
Bmc Musculoskeletal Disorders
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
2016-01
Subject
The topic of the resource
carpal-tunnel-syndrome; disorders; endothelial-cells; extracellular-matrix; gene-expression; Heat shock protein; human fibroblasts; Metalloproteinases; muscle; musculoskeletal; Orthopedics; Osteoactivin; Overuse; posttranscriptional; regulation; Restorative repair; Rheumatology; skeletal-muscle regeneration; Tendon; transgenic expression; upper extremity
Creator
An entity primarily responsible for making the resource
Frara N; Abdelmagid S M; Tytell M; Amin M; Popoff S N; Safadi F F; Barbe M F
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1186/s12891-016-0892-3" target="_blank" rel="noreferrer noopener">10.1186/s12891-016-0892-3</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2016
Abdelmagid S M
Amin M
Barbe M F
BMC musculoskeletal disorders
carpal-tunnel-syndrome
disorders
endothelial-cells
extracellular-matrix
Frara N
gene-expression
Heat shock protein
human fibroblasts
Metalloproteinases
Muscle
musculoskeletal
Orthopedics
OSTEOACTIVIN
Overuse
Popoff S N
posttranscriptional
regulation
Restorative repair
Rheumatology
Safadi F F
skeletal-muscle regeneration
tendon
transgenic expression
Tytell M
Upper Extremity
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
2-2
Volume
25
Search for Full-text
Locate full-text within NEOMED Library's e-journal collections
<p>Users with a NEOMED Library login can search for full-text journal articles at the following url: <a href="https://libraryguides.neomed.edu/home">https://libraryguides.neomed.edu/home</a></p>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Osteoactivin, Inducible Heat Shock Protein 70 And Transforming Growth Factor Beta 1 Expression In Skeletal Muscle Of High Repetitive High Force Reaching Rats In Association With Anti-inflammatory Drugs
Publisher
An entity responsible for making the resource available
Molecular Biology of the Cell
Date
A point or period of time associated with an event in the lifecycle of the resource
2014
2014-12
Subject
The topic of the resource
Cell Biology
Creator
An entity primarily responsible for making the resource
Frara N; Abdelmagid S M; Fisher P W; Popoff S N; Safadi F F; Barbe M F
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2014
Abdelmagid S M
Barbe M F
Cell Biology
Fisher P W
Frara N
Molecular Biology of the Cell
Popoff S N
Safadi F F
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
n/a
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
1-1
Volume
24
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Osteoactivin, Mmp And Hsp70 Expression In Skeletal Muscle In A Rat Model Of Repetitive Loading
Publisher
An entity responsible for making the resource available
Molecular Biology of the Cell
Date
A point or period of time associated with an event in the lifecycle of the resource
2013
2013
Subject
The topic of the resource
Cell Biology
Creator
An entity primarily responsible for making the resource
Frara N; Abdelmagid S M; Tytell M; Popoff S N; Safadi F F; Barbe M F
Identifier
An unambiguous reference to the resource within a given context
n/a
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2013
Abdelmagid S M
Barbe M F
Cell Biology
Frara N
Molecular Biology of the Cell
Popoff S N
Safadi F F
Tytell M
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1371/journal.pone.0038359" target="_blank" rel="noreferrer noopener">http://doi.org/10.1371/journal.pone.0038359</a>
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Pages
13-13
Issue
5
Volume
7
Search for Full-text
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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Performance of Repetitive Tasks Induces Decreased Grip Strength and Increased Fibrogenic Proteins in Skeletal Muscle: Role of Force and Inflammation
Publisher
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PLOS ONE
Date
A point or period of time associated with an event in the lifecycle of the resource
2012
2012-05
Subject
The topic of the resource
carpal-tunnel-syndrome; factor gene-expression; flexor tendon cells; in-vivo; lengthening contractions; necrosis-factor-alpha; rat model; Science & Technology - Other Topics; strain injury; tissue growth-factor; tnf-alpha
Creator
An entity primarily responsible for making the resource
Abdelmagid S M; Barr A E; Rico M; Amin M; Litvin J; Popoff S N; Safadi F; Barbe M F
Description
An account of the resource
Background: This study elucidates exposure-response relationships between performance of repetitive tasks, grip strength declines, and fibrogenic-related protein changes in muscles, and their link to inflammation. Specifically, we examined forearm flexor digitorum muscles for changes in connective tissue growth factor (CTGF; a matrix protein associated with fibrosis), collagen type I (Col1; a matrix component), and transforming growth factor beta 1 (TGFB1; an upstream modulator of CTGF and collagen), in rats performing one of two repetitive tasks, with or without anti-inflammatory drugs. Methodology/Results: To examine the roles of force versus repetition, rats performed either a high repetition negligible force food retrieval task (HRNF), or a high repetition high force handle-pulling task (HRHF), for up to 9 weeks, with results compared to trained only (TR-NF or TR-HF) and normal control rats. Grip strength declined with both tasks, with the greatest declines in 9-week HRHF rats. Quantitative PCR (qPCR) analyses of HRNF muscles showed increased expression of Col1 in weeks 3-9, and CTGF in weeks 6 and 9. Immunohistochemistry confirmed PCR results, and also showed greater increases of CTGF and collagen matrix in 9-week HRHF rats than 9-week HRNF rats. ELISA, and immunohistochemistry revealed greater increases of TGFB1 in TR-HF and 6-week HRHF, compared to 6-week HRNF rats. To examine the role of inflammation, results from 6-week HRHF rats were compared to rats receiving ibuprofen or anti-TNF-alpha treatment in HRHF weeks 4-6. Both treatments attenuated HRHF-induced increases in CTGF and fibrosis by 6 weeks of task performance. Ibuprofen attenuated TGFB1 increases and grip strength declines, matching our prior results with anti-TNF alpha. Conclusions/Significance: Performance of highly repetitive tasks was associated with force-dependent declines in grip strength and increased fibrogenic-related proteins in flexor digitorum muscles. These changes were attenuated, at least short-term, by anti-inflammatory treatments.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1371/journal.pone.0038359" target="_blank" rel="noreferrer noopener">10.1371/journal.pone.0038359</a>
Format
The file format, physical medium, or dimensions of the resource
Journal Article or Conference Abstract Publication
2012
Abdelmagid S M
Amin M
Barbe M F
Barr A E
carpal-tunnel-syndrome
factor gene-expression
flexor tendon cells
in-vivo
Journal Article or Conference Abstract Publication
lengthening contractions
Litvin J
necrosis-factor-alpha
PloS one
Popoff S N
rat model
Rico M
Safadi F
Science & Technology - Other Topics
strain injury
tissue growth-factor
TNF-alpha