Browse Items (4 total)
- Tags: Barnes Kendra F
Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.
Tags: *Phytotherapy, 2012, Alkylating Agents/toxicity, Animals, Anthocyanins/*therapeutic use, Antioxidants/therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Blotting, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diet, Diethylnitrosamine/toxicity, Experimental/chemically induced/metabolism/*prevention & control, Glutathione Transferase, Haznagy-Radnai Erzsebet, Hepatocellular/chemically induced/metabolism/*prevention & control, Hohmann Judit, Immunoenzyme Techniques, Lipid Peroxidation/drug effects, Liver Neoplasms, Male, Messenger/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/genetics/*metabolism, Nitric Oxide Synthase Type II/genetics/metabolism, Oxidative Stress/*drug effects, Rats, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Ribes/*chemistry, RNA, Signal Transduction, Sprague-Dawley, Thoppil Roslin J, Tyrosine/analogs & derivatives/metabolism, Western
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Tags: 2010, Animals, Antioxidants/*pharmacology/therapeutic use, Antitumor, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Cancer prevention research (Philadelphia, Pa.), Carcinogens/toxicity, Carroll Richard T, Chemical and Drug Induced Liver Injury/*etiology/metabolism/pathology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine/toxicity, Dose-Response Relationship, Drug, Drug Screening Assays, Enzyme Induction/drug effects, Experimental/chemically induced/metabolism/pathology/*prevention & control, Female, Hyperplasia, Inflammation/*prevention & control, Lipid Peroxidation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism/pathology, Messenger/biosynthesis/genetics, NEOMED College of Pharmacy, NF-E2-Related Factor 2/biosynthesis/genetics, Nitric Oxide Synthase Type II/biosynthesis/genetics, Oxidative Stress/*drug effects, Phenobarbital/toxicity, Precancerous Conditions/*chemically induced/metabolism/pathology, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/*pharmacology/therapeutic use, Tyrosine/analogs & derivatives/analysis
Tags: *Drug Design, 2010, Animals, Barnes Kendra F, Binding Sites/drug effects/physiology, Bioorganic & medicinal chemistry letters, Carroll Richard T, Dose-Response Relationship, Drug, Drug Delivery Systems/*methods, Funk Max O, Geldenhuys Werner J, Liver/drug effects/metabolism, Mitochondria, Mitochondrial Proteins/*metabolism, Protein Structure, Rats, Secondary, Structure-Activity Relationship, Thiazolidinediones/administration & dosage/*chemical synthesis/*metabolism
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.
Tags: 2010, Animals, Anticarcinogenic Agents/*therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Chatterjee Malay, Chemoprevention, Cyclooxygenase 2/immunology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Female, HSP70 Heat-Shock Proteins/immunology, Humans, Inflammation/prevention & control, Liver Neoplasms/chemically induced/*immunology/*prevention & control, Liver/drug effects/pathology, Mbimba Thomas, NEOMED College of Pharmacy, NF-kappa B/immunology, Pharmaceutical research, Rats, Resveratrol, Sprague-Dawley, Stilbenes/*therapeutic use, Waghray Abhijeet