Browse Items · NEOMED Bibliography Database

A novel biomechanical analysis of gait changes in the MPTP mouse model of Parkinson's disease.

Parkinson's disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mesencephalic dopaminergic neurons. Accurate recapitulation of the PD movement phenotype in animal models of the disease is critical for understanding…

Tags: 2015, Behavior, Department of Anatomy & Neurobiology, Dluzen Dean E, Gait, Geldenhuys Werner J, Gender-bias, Guseman Tamara L, Locomotion, MPTP, NEOMED College of Medicine, PeerJ, Pienaar Ilse S, Young Jesse W

A practice change model for quality improvement in primary care practice

Faced with a rapidly changing healthcare environment, primary care practices often have to change how they practice medicine. Yet change is difficult, and the process by which practice improvement can be understood and facilitated has not been well…

Abderitid Marsupials From The Miocene Of Patagonia: An Assessment Of Form, Function, And Evolution

Tags: 2000, argentina, Australia, Behavior, burramyidae, dasyuridae, dental function, Diet, Dumont E R, Friscia A R, Journal of Paleontology, Mammals, morphology, Paleontology, pygmy-possum, Strait S G

Accessing foods can exert multiple distinct, and potentially competing, selective pressures on feeding in common marmoset monkeys

Animals must overcome the physical properties protecting foods to obtain nutrition. While animals can experience selection for traits that facilitate resource exploitation, specific feeding behaviors may entail multiple, different mechanical…

Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat.

Specific behaviors comprising the serotonin syndrome (low body posture, forepaw treading, headweaving) and the autonomic signs of piloerection and salivation were determined and analyzed with locomotor activity in response to MDMA at three doses…

Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease.

Traumatic brain injury (TBI) has acute and chronic sequelae, including an increased risk for the development of Alzheimer's disease (AD). TBI-associated neuroinflammation is characterized by activation of brain-resident microglia and infiltration of…

Appraising Cultural Identity In Career-development Assessment And Counseling

Career-Development Assessment and Counseling (C-DAC) systematically bridges career theory and practice. Integrating differential, developmental, and phenomenological methods, the C-DAC model uses a comprehensive career assessment battery to help…

Biopsychosocial characteristics of overweight and obese primary care patients: do psychosocial and behavior factors mediate sociodemographic effects?

Background. The increasing prevalence of obesity and obesity-related conditions in primary care settings challenges the health care system. Thus. we used available baseline data from an on-going clinical trial to examine the biopsychosocial…

Candyflipping': synergistic discriminative effect of LSD and MDMA.

The co-administration of D-lysergic acid diethylamide (LSD; 'Acid') and 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'; 'XTC'), has reached a prevalence that has allowed for the street terminology 'candyflipping' to describe the combination.…

Tags: 1998, 4-methylenedioxyamphetamine/administration & dosage/*pharmacology, Animal/*drug effects, Animals, Behavior, Discrimination Learning/*drug effects, Drug Synergism, European journal of pharmacology, Hallucinogens/administration & dosage/*pharmacology, Lysergic Acid Diethylamide/administration & dosage/*pharmacology, Male, N-Methyl-3, Rats, Schechter M D, Serotonin Agents/administration & dosage/*pharmacology

Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC), one of the most lethal cancers, results in more than one million fatalities worldwide every year. In view of the limited therapeutic alternatives and poor prognosis of liver cancer, preventive control approaches,…

Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western

Comparison of the behavioral effects of ibogaine from three sources: mediation of discriminative activity.

Ibogaine is an alkaloid employed for its hallucinatory properties in West Central Africa which has been the subject of alleged efficacy as an aid in the interruption and treatment of chemical dependency. The major sources of the Schedule I agent are:…

Tags: *Discrimination (Psychology), 1993, Animal/*drug effects, Animals, Behavior, Dose-Response Relationship, Drug, European journal of pharmacology, Gordon T L, Ibogaine/*pharmacology, Male, Rats, Schechter M D, Serotonin Receptor Agonists/pharmacology, Sprague-Dawley

Connecting the dots–establishing causality between chronic stress, depression, and cardiovascular disease.

Cross Sectional Geometry of the Forelimb Skeleton and Flight Mode in Pelecaniform Birds

Avian wing elements have been shown to experience both dorsoventral bending and torsional loads during flapping flight. However, not all birds use continuous flapping as a primary flight strategy. The pelecaniforms exhibit extraordinary diversity in…

Daily spontaneous running alters behavioral and neurochemical indexes of nigrostriatal function.

Behavioral and neurochemical indexes of nigrostriatal dopaminergic function were compared between sedentary control rats (n = 12) and daily spontaneous running (DSR) male rats (n = 10). Nine weeks of DSR did not significantly alter body, heart,…

Decompression syndrome and the evolution of deep diving physiology in the Cetacea

Whales repetitively dive deep to feed and should be susceptible to decompression syndrome, though they are not known to suffer the associated pathologies. Avascular osteonecrosis has been recognized as an indicator of diving habits of extinct marine…

Dose-response effects of estrogen and tamoxifen upon methamphetamine-induced behavioral responses and neurotoxicity of the nigrostriatal dopaminergic system in female mice.

In the present experiment we evaluated the dose-response effects of estrogen (estradiol benzoate; EB) and tamoxifen (TMX) in modulating the acute behavioral and chronic effects of methamphetamine (MA) upon the nigrostriatal dopaminergic (NSDA) system…

Drug samples in dermatology: Special considerations and recommendations for the future

Background: The use of drug samples is a controversial issue in medicine. Objective: We sought to determine the pros and cons of drug sampling, and how drug sampling in general medicine differs from dermatology. Methods: Literature searches were…

Effects And Generalizability Of Communally Oriented Hiv-aids Prevention Versus General Health Promotion Groups For Single, Inner-city Women In Urban Clinics

A primary prevention, behavioral intervention designed to reduce HIV risk behavior was tested in a randomized, controlled trial with single, inner-city women. A total of 935 women were randomly assigned to 1 of 3 conditions: a small group, 6-session…

Tags: 2002, adolescents, african-american women, Behavior, Hobfoll S E, impact, Infection, Jackson A P, Johnson R J, Journal Article or Conference Abstract Publication, Journal of Consulting and Clinical Psychology, Lavin J, outcomes, Psychology, randomized controlled trial, risk-reduction interventions, Schroder K E E, sexual risk, united-states

Effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat.

The effects of gender and gonadal hormones on nociceptive responses to intraplantar carrageenan in the rat were investigated. A plantar analgesic meter was used to measure carrageenan-induced changes in paw withdrawal latency (PWL) values, and von…

Gender and the behavioral manifestations of neuropathic pain.

A model of peripheral nerve injury was used to study gender differences in the development and progression of chronic constriction injury (CCI)-induced hyperalgesia and allodynia in male and female Fischer 344 FBNF1 hybrid rats. Rats were randomly…

HAS and LAS rats respond differentially to behavioral effects of ethanol, pentobarbital, chlorpromazine and chlordiazepoxide.

The drug discrimination paradigm (DD) was used to evaluate differences in performance of rats selectively bred for differential sensitivity to the hypnotic effects of ethanol. Tenth generation high-alcohol sensitive (HAS) and low-alcohol sensitive…

Tags: *Hypnotics and Sedatives, 1991, Animal/*drug effects, Animals, Behavior, Chlordiazepoxide/*pharmacology, Chlorpromazine/*pharmacology, Discrimination (Psychology)/drug effects, Ethanol/*pharmacology, Krimmer E C, Male, Motor Activity/drug effects, Pentobarbital/*pharmacology, Pharmacology, biochemistry, and behavior, Rats, Sleep/drug effects

Interaction of ethanol and tetrahydro-beta-carboline (THBC) in a discriminative task.

Rats (n = 10) were trained to discriminate between ethanol (600 mg/kg, IP) and its vehicle, or between THBC (20 mg/kg) and its vehicle in a two-lever food-motivated operant task. Once the discriminative training criterion was attained, rats in each…

Tags: 1988, Alcohol (Fayetteville, N.Y.), Animal/drug effects, Animals, Behavior, Carbolines/*pharmacology, Conditioning (Psychology)/drug effects, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Interactions, Ethanol/*pharmacology, Inbred Strains, Male, Rats, Schechter M D, Signs S A

Intramuscular antagonism of the G-protein coupled estrogen receptor 1 partially affects dimorphic characteristics of the syrinx, but is ineffective within the neural song circuit of zebra finches

Within the zebra finch song system, robust sex differences exist that enable singing behavior in males, but not females. Estradiol is a potent contributor to this process, but how and through which receptor(s) it acts is not clear. Historically,…

Is pathological gambling really a problem? – You bet!

Tags: 2001, Addictive, Behavior, Castellani B, Gambling, Psychiatric Times

Jaw-muscle architecture and mandibular morphology influence relative maximum jaw gapes in the sexually dimorphic Macaca fascicularis.

Maximum jaw gape is a performance variable related to feeding and non-feeding oral behaviors, such as canine gape displays, and is influenced by several factors including jaw-muscle fiber architecture, muscle position on the skull, and jaw…

Methodological optimization of tinnitus assessment using prepulse inhibition of the acoustic startle reflex.

Recently prepulse inhibition of the acoustic startle reflex (ASR) became a popular technique for tinnitus assessment in laboratory animals. This method confers a significant advantage over the previously used time-consuming behavioral approaches…

Tags: 2012, Acoustic Stimulation/instrumentation/*methods, Animal/physiology, Animals, Behavior, Brain research, Department of Anatomy & Neurobiology, Galazyuk A V, Habituation, Longenecker R J, Mice, NEOMED College of Medicine, Psychophysiologic/physiology, Reflex, Startle/*physiology, Tinnitus/*diagnosis/physiopathology

Morphological Correlates Of Substrate Use In Didelphid Marsupials: Implications For Primate Origins

The ability of some mammals to forage on vines or terminal branches depends upon their grasping extremities. This study tests the functional link between use of small-diameter supports and grasping abilities by comparing hand and foot proportions in…

Myological Correlates Of Prosimian Leaping

Tags: 1998, Anthropology, Behavior, Body Size, coordination, Demes B, Evolutionary Biology, Fleagle J G, Journal of human evolution, Kinematics, Kinetics, Lemelin P, Locomotion, morphology, Primates, relative muscle masses, strepsirhines, vertical clingers and leapers

Neuropathic pain in aged rats: behavioral responses and astrocytic activation.

We used the Bennett and Xie (1988) model of chronic neuropathic pain to study the effect of age on thermal and tactile sensitivity and on astrocytic activation in the dorsal horn of the spinal cord after nerve injury. Fischer 344 FBNF1 hybrid rats in…

Nisoxetine infusion into the olfactory bulb enhances the capacity for male rats to identify conspecifics.

In the present report, the norepinephrine uptake inhibitor nisoxetine as well as a cocktail of nisoxetine and the alpha-adrenergic receptor antagonist phentolamine were infused unilaterally into the olfactory bulb during microdialysis to assess their…

Non-Monogamous Copulations and Potential Within-Group Mating Competition in White-Faced Saki Monkeys (Pithecia pithecia)

Many primates display within-species variation in social organization and mating system. Individuals of these species may be confronted with both the challenges of between-group competition to exclude same-sex competitors as well as within-group…

Tags: 2013, aggression, American journal of primatology, Behavior, group-dynamics, harassment, japanese macaques, Journal Article, mating harassment, mating system, multimale, pair living, Primate, sexual coercion, social-organization, sperm, Thompson C L, Zoology

Norfenfluramine, the fenfluramine metabolite, provides stimulus control: evidence for serotonergic mediation.

Nine male rats were trained to discriminate 1.4 mg/kg norfenfluramine (NF) from its vehicle using a two-lever, food-motivated, operant discrimination task. Once trained, the rats showed a dose-dependent decrease in responding on the

Tags: 1988, Animal/*drug effects, Animals, Behavior, Boja J W, Discrimination (Psychology)/*drug effects, Dose-Response Relationship, Drug, Fenfluramine/*analogs & derivatives/*pharmacology, Inbred Strains, Male, Norfenfluramine/*pharmacology, Pharmacology, biochemistry, and behavior, Rats, Receptors, Schechter M D, Serotonin/pharmacology, Serotonin/physiology, Time Factors

Obesity-related endometrial cancer: an update on survivorship approaches to reducing cardiovascular death.

As the rate of obesity increases worldwide, so will the number of women diagnosed with obesity-related malignancy. The strongest correlation between obesity and cancer is endometrial cancer (EC). Obesity is the most significant modifiable risk factor…

Olanzapine attenuates the reinforcing effects of cocaine.

The possibility that the atypical neuroleptic olanzapine can antagonize the ability of cocaine to produce both conditioned place preference and self-administration in rats was investigated. Pre-treatment with olanzapine (3.0, 4.5 mg/kg, but not 1.5…

Phenobarbital pre-treatment prevents kainic acid-induced impairments in acquisition learning.

This study examined the protective effect of phenobarbital on kainic acid-induced deficits in acquisition learning. A single kainic acid injection (9 mg/kg i.p.) was administered five days prior to testing using the Morris water maze test. Kainic…

Premorbid behaviors produced by cocaine, ethanol and cocaethylene in the mouse.

1. The premorbid behaviors produced by the administration of cocaine, ethanol, their combination, as well as a metabolite produced by their co-administration, viz. cocaethylene, were defined, determined and quantified in the HS strain of mice. 2. The…

Tags: 1995, Animal/*drug effects, Animals, Behavior, Cocaine/*analogs & derivatives/*toxicity, Dose-Response Relationship, Drug, Ethanol/*toxicity, Female, General pharmacology, Lethal Dose 50, Male, Meehan S M, Mice, Schechter M D

Prolactin Stimulates Dopamine Release From The Rat Corpus Striatum In The Absence Of Extracellular Calcium

Prolactin (PRL) increased basal dopamine (DA) release and attenuated amphetamine (AMPH)-stimulated DA release in vitro from rat corpus striatum in a concentration-dependent manner with 10(-5) M PRL being the most effective. The effects of PRL on DA…

Tags: 1991, amphetamine, Behavior, binding-sites, Brain, calcium, cerebrospinal-fluid, corpus striatum, Dluzen D E, Dopamine, Hypothalamus, in-vitro, Journal Article or Conference Abstract Publication, Laping N J, Neuroscience letters, Neurosciences & Neurology, prolactin, Ramirez V D, rat

PTSD, Depression, and Substance Use in Relation to Suicidality Risk among Traumatized Minority Lesbian, Gay, and Bisexual Youth

Youths who are lesbian, gay, or bisexual (LGB) are more likely than heterosexuals to commit suicide. Substance use, PTSD, and depression are independent risk factors for suicidality; however, the extent to which these factors interact to predict…

Rats bred for differences in preference to cocaine: other behavioral measurements.

Cocaine has repeatedly been shown to produce conditioned place preference (CPP) in the rat. The present study employed the heterogenous N/Nih rat stock to produce a selectively bred rat line determined by individual place preference to a conditioning…

Tags: 1992, Animal/*drug effects, Animals, Behavior, Choice Behavior/*drug effects, Cocaine/*pharmacology, Dose-Response Relationship, Drug, Female, Inbred Strains, Male, Motor Activity/drug effects, Pharmacology, biochemistry, and behavior, Rats, Schechter M D, Species Specificity, Sprague-Dawley

Reason, Intuition, And Social Justice: Elaborating On Parsons's Career Decision-making Model

Nearly a century ago, Frank Parsons established the Vocation Bureau in Boston and spawned the development of the counseling profession. Elaborating on Parsons's socially responsible vision for counseling, the authors examine contemporary perspectives…

Tags: 2002, Behavior, Blustein D L, choice, Department of Family & Community Medicine, Hartung P J, Intervention, Journal Article or Conference Abstract Publication, Journal of Counseling and Development, NEOMED College of Medicine, opportunities, Psychology, Work

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