1
40
12
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ccd.27840" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ccd.27840</a>
Pages
345-353
Issue
2
Volume
93
ISSN
1522-726X
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Safety and efficacy of transcatheter aortic valve replacement for native aortic valve regurgitation: A systematic review and meta-analysis.
Publisher
An entity responsible for making the resource available
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-02-01
Subject
The topic of the resource
Female; Humans; Male; Aged; Middle Aged; Treatment Outcome; Risk Factors; Aged 80 and over; Risk Assessment; Prosthesis Design; Recovery of Function; Heart Valve Prosthesis; Aortic Valve/diagnostic imaging/physiopathology/surgery; aortic valve insufficiency; heart diseases; heart valve prosthesis; Transcatheter Aortic Valve Replacement/adverse effects/instrumentation/mortality; Aortic Valve Insufficiency/diagnostic imaging/mortality/physiopathology/surgery
Creator
An entity primarily responsible for making the resource
Rawasia WF; Khan MS; Usman MS; Siddiqi TJ; Mujeeb FA; Chundrigar M; Kalra A; Alkhouli M; Kavinsky CJ; Bhatt DL
Description
An account of the resource
OBJECTIVE: The objective of this study was to analyze the available literature on using transcatheter aortic valve replacement (TAVR) for native aortic regurgitation (AR). BACKGROUND: Surgical aortic valve replacement is the gold standard therapy for native AR. TAVR has emerged as an alternative approach in high-risk patients. METHODS: MEDLINE, Scopus, and Cochrane CENTRAL were searched for reports of at least 5 patients undergoing TAVR for native AR. Outcomes included 30-day mortality, myocardial infarction, stroke, major bleeding, postprocedural moderate to severe AR, and device success. Pooled estimates were calculated using a random-effects model. Subgroup analysis and a meta-regression were performed to study the effects of study level covariates on outcomes. RESULTS: Nineteen studies (n =998 patients) were included. The rate of procedural success per Valve Academic Research Consortium - 2 (VARC-2) criteria was 86.2% (78.8%-92.2%]. Thirty-day mortality was 11.9% (9.4%-14.7%). Subgroup analysis showed the use of new generation valves was associated with lower 30-day mortality (P = 0.02) and higher device success (P = 0.009) compared with early generation valves. There was no significant difference (P = 0.13) in the rate of 30-day mortality between patients receiving purpose-specific [8.2% (4.3%-13.1%); I2 = 0%] and nonpurpose specific valves [13.0% (8.2%-18.6%); I2 = 25%]. However, device success was higher (P = 0.02) in patients who received purpose-specific valves [96.3% (92.2%-98.9%); I2 = 0%] compared with nonpurpose specific valves [84.4% (75%-91.9%); I2 =46%]. CONCLUSION: TAVR for native AR is associated with acceptable procedural success but increased early mortality. However, the safety and the efficacy of the procedure increased with newer valves.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ccd.27840" target="_blank" rel="noreferrer noopener">10.1002/ccd.27840</a>
PMID: 30269437
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© 2018 Wiley Periodicals, Inc.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Aged
Aged 80 and over
Alkhouli M
aortic valve insufficiency
Aortic Valve Insufficiency/diagnostic imaging/mortality/physiopathology/surgery
Aortic Valve/diagnostic imaging/physiopathology/surgery
Bhatt DL
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Chundrigar M
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Female
heart diseases
Heart Valve Prosthesis
Humans
journalArticle
June2020SubmittedList
Kalra A
Kavinsky CJ
Khan MS
Male
Middle Aged
Mujeeb FA
NEOMED College of Medicine
Prosthesis Design
Rawasia WF
Recovery of Function
Risk Assessment
Risk Factors
Siddiqi TJ
Transcatheter Aortic Valve Replacement/adverse effects/instrumentation/mortality
Treatment Outcome
Usman MS
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.amjcard.2018.09.039" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.amjcard.2018.09.039</a>
Pages
218-226
Issue
2
Volume
123
ISSN
1879-1913 0002-9149
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
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Department of Internal Medicine
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Cleveland Clinic Akron General Hospital
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Title
A name given to the resource
Meta-analysis comparing culprit vessel only versus multivessel percutaneous coronary intervention in patients with acute myocardial infarction and cardiogenic shock.
Publisher
An entity responsible for making the resource available
The American journal of cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-01-15
Subject
The topic of the resource
Humans; Recurrence; Retreatment; Percutaneous Coronary Intervention/methods; Coronary Artery Disease/therapy; Myocardial Infarction/mortality/therapy; Renal Insufficiency/epidemiology; Shock Cardiogenic/mortality
Creator
An entity primarily responsible for making the resource
Khan MS; Siddiqi TJ; Usman MS; Riaz H; Khan AR; Murad MH; Kalra A; Figueredo VM; Bhatt DL
Description
An account of the resource
Cardiogenic shock (CS) after a myocardial infarction continues to be associated with high mortality. Whether percutaneous coronary intervention (PCI) of noninfarct coronary arteries (multivessel intervention [MVI]) improves outcomes in CS after acute myocardial infarction (AMI) remains controversial. MEDLINE, Cochrane CENTRAL, and Scopus databases were searched for original studies comparing MVI with culprit-vessel intervention (CVI) in AMI patients with multivessel disease and CS. Risk ratios (RRs) and 95% confidence intervals were calculated and pooled using a random effects model. Thirteen studies, consisting of 7,906 patients (n(MVI) = 1,937; n(CVI) = 5,969), were included in this meta-analysis. Overall, the MVI and CVI groups did not differ significantly in the risk of short-term mortality (RR: 1.06 [0.91, 1.23]; p = 0.45; I(2) = 75.82%), long-term mortality (RR: 0.93 [0.78, 1.11]; p = 0.37; I(2) = 67.92%), reinfarction (RR: 1.16 [0.75, 1.79]; p = 0.50; I(2) = 0%), revascularization (RR: 0.84 [0.48, 1.47]; p = 0.54; I(2) = 83.01%), bleeding (RR: 1.15 [0.96, 1.38]; p = 0.09, I(2) = 0%), or stroke (RR: 1.29 [0.86, 1.94]; p = 0.80, I(2) = 0%). However, significantly increased risk of renal failure was seen in the MVI group (RR: 1.35 [1.10, 1.66]; p = 0.004; I(2) = 0%). On subgroup analysis, it was seen that results from retrospective studies showed higher short-term mortality in the MVI group in comparison with prospective studies (p = 0.003). The certainty in estimates is low due to the largely observational nature of the evidence. In conclusion, MVI provides no additional reduction in short- or long-term mortality in AMI patients with multivessel disease and CS. Additionally, the risk of renal failure may be higher with the use of MVI.
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<a href="http://doi.org/10.1016/j.amjcard.2018.09.039" target="_blank" rel="noreferrer noopener">10.1016/j.amjcard.2018.09.039</a>
PMID: 30420183
Rights
Information about rights held in and over the resource
Copyright © 2018. Published by Elsevier Inc.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Bhatt DL
Cleveland Clinic Akron General Hospital
Coronary Artery Disease/therapy
Department of Internal Medicine
Figueredo VM
Humans
journalArticle
June2020SubmittedList
Kalra A
Khan AR
Khan MS
Murad MH
Myocardial Infarction/mortality/therapy
NEOMED College of Medicine
Percutaneous Coronary Intervention/methods
Recurrence
Renal Insufficiency/epidemiology
Retreatment
Riaz H
Shock Cardiogenic/mortality
Siddiqi TJ
The American journal of cardiology
Usman MS
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.jchf.2018.10.011" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jchf.2018.10.011</a>
Pages
112-117
Issue
2
Volume
7
ISSN
2213-1787
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
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Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
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Title
A name given to the resource
Effect of influenza on outcomes in patients with heart failure.
Publisher
An entity responsible for making the resource available
Journal of the American College of Cardiology. Heart failure
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-02
Subject
The topic of the resource
Female; Humans; Male; Aged; Retrospective Studies; Risk Factors; United States/epidemiology; Incidence; Follow-Up Studies; heart failure; hospitalization; Hospitalization/trends; vaccination; influenza; Survival Rate/trends; Risk Assessment/methods; Inpatients; Morbidity/trends; Hospital Mortality/trends; Propensity Score; Heart Failure/complications/epidemiology; Influenza Human/complications/epidemiology/prevention & control; Vaccination/methods
Creator
An entity primarily responsible for making the resource
Panhwar MS; Kalra A; Gupta T; Kolte D; Khera S; Bhatt DL; Ginwalla M
Description
An account of the resource
OBJECTIVES: This study sought to determine whether influenza infection increases morbidity and mortality in patients hospitalized with heart failure (HF). BACKGROUND: Patients with HF may be at increased risk of morbidity and mortality from influenza infection. However, there are limited data for the associated hazards of influenza infection in patients with HF. METHODS: We queried the 2013 to 2014 National Inpatient Sample database for all adult patients (18 years of age or older) admitted with HF with and without concomitant influenza infection. Propensity score matching was used to match patients across age, race, sex, and comorbidities. Outcomes included in-hospital mortality, in-hospital complications, length of stay, and average hospital costs. RESULTS: Of 8,189,119 all-cause hospitalizations in patients with HF, 54,590 (0.67%) had concomitant influenza infection. Patients with concomitant influenza had higher incidence of in-hospital mortality (6.2% vs. 5.4%, respectively; odds ratio [OR]: 1.15 [95% confidence interval [CI]: 1.03 to 1.30]; p = 0.02), acute respiratory failure (36.9% vs. 23.1%, respectively; OR: 1.95 [95% CI: 1.83 to 2.07]; p < 0.001), acute respiratory failure requiring mechanical ventilation (18.2% vs. 11.3%, respectively; OR: 1.75 [95% CI: 1.62 to 1.89]; p < 0.001), acute kidney injury (AKI) (30.3% vs. 28.7%, respectively; OR: 1.08 [95% CI: 1.02 to 1.15]; p = 0.01), and AKI requiring dialysis (2.4% vs. 1.8%, respectively; OR: 1.37 [95% CI: 1.14 to 1.65]; p = 0.001). Patients with influenza had longer mean lengths of stay (5.9 days vs. 5.2 days, respectively; p <0.001) but similar average hospital costs ($12,137 vs. $12,003, respectively; p = 0.40). CONCLUSIONS: Influenza infection is associated with increased in-hospital morbidity and mortality in patients with HF. Our results emphasize the need for efforts to mitigate the incidence of influenza, specifically in this high-risk patient cohort.
Identifier
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<a href="http://doi.org/10.1016/j.jchf.2018.10.011" target="_blank" rel="noreferrer noopener">10.1016/j.jchf.2018.10.011</a>
PMID: 30611718
Rights
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Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Aged
Bhatt DL
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Female
Follow-Up Studies
Ginwalla M
Gupta T
Heart failure
Heart Failure/complications/epidemiology
Hospital Mortality/trends
Hospitalization
Hospitalization/trends
Humans
Incidence
Influenza
Influenza Human/complications/epidemiology/prevention & control
Inpatients
Journal of the American College of Cardiology. Heart failure
journalArticle
June2020SubmittedList
Kalra A
Khera S
Kolte D
Male
Morbidity/trends
NEOMED College of Medicine
Panhwar MS
Propensity Score
Retrospective Studies
Risk Assessment/methods
Risk Factors
Survival Rate/trends
United States/epidemiology
vaccination
Vaccination/methods
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.amjcard.2019.01.046" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.amjcard.2019.01.046</a>
Pages
1478-1480
Issue
9
Volume
123
ISSN
1879-1913
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Update Year & Number
June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
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Title
A name given to the resource
Relation of concomitant heart failure to outcomes in patients hospitalized with influenza.
Publisher
An entity responsible for making the resource available
The American journal of cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-05-01
Subject
The topic of the resource
Female; Humans; Male; Aged; Middle Aged; Retrospective Studies; United States/epidemiology; Incidence; Comorbidity; Follow-Up Studies; Survival Rate/trends; Hospitalization/statistics & numerical data; Inpatients; Length of Stay/trends; Heart Failure/epidemiology; Hospital Mortality/trends; Influenza Human/epidemiology
Creator
An entity primarily responsible for making the resource
Panhwar MS; Kalra A; Gupta T; Kolte D; Khera S; Bhatt DL; Ginwalla M
Description
An account of the resource
Influenza is a major public health challenge. Patients hospitalized with influenza who also have heart failure (HF) may be at risk for worse outcomes compared with patients without HF. There is a lack of large studies examining this issue. We queried the 2013 to 2014 National Inpatient Sample for all adult patients (aged ≥ 18 years) admitted with influenza with and without concomitant HF. Using propensity score matching, patients were matched across demographics, discharge weights, and comorbidities. Outcomes included in-hospital mortality, complications, length of stay, and average hospital costs. Of 218,540 influenza hospitalizations, 45,460 (20.8%) had concomitant HF. Patients with HF had higher in-hospital mortality (6.1% vs 3.8%, adjusted odds ratio [aOR] 1.66 [95% confidence interval [CI] 1.44 to 1.91]; p <0.001), acute kidney injury (29.5% vs 22.2%, aOR 1.47 [95% CI 1.37 to 1.57]; p <0.001), acute kidney injury requiring dialysis (2.0% vs 1.0%, aOR 2.08 [1.62 to 2.67], acute respiratory failure (36.2% vs 23.5%, aOR 1.85 [1.73 to 1.97]; p <0.001), and acute respiratory failure requiring mechanical ventilation (17.1% vs 9.3%, OR 2.01 [1.84 to 2.21]; p <0.001), longer length of stay (5.70 ± 0.02 days vs 4.60 ± 0.01 days, p <0.001) and higher average hospital costs ($11,609 ± $52 vs $9,003 ± $38, p <0.001). In conclusion, in patients hospitalized with influenza, HF is associated with increased risk of in-hospital mortality and complications. Our results highlight a need for early recognition and aggressive treatment of HF in these patients to try to improve outcomes.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/j.amjcard.2019.01.046" target="_blank" rel="noreferrer noopener">10.1016/j.amjcard.2019.01.046</a>
PMID: 30819433
Rights
Information about rights held in and over the resource
Copyright © 2019 Elsevier Inc. All rights reserved.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Aged
Bhatt DL
Cleveland Clinic Akron General Hospital
Comorbidity
Department of Internal Medicine
Female
Follow-Up Studies
Ginwalla M
Gupta T
Heart Failure/epidemiology
Hospital Mortality/trends
Hospitalization/statistics & numerical data
Humans
Incidence
Influenza Human/epidemiology
Inpatients
journalArticle
June2020SubmittedList
Kalra A
Khera S
Kolte D
Length of Stay/trends
Male
Middle Aged
NEOMED College of Medicine
Panhwar MS
Retrospective Studies
Survival Rate/trends
The American journal of cardiology
United States/epidemiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/ccd.28310" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/ccd.28310</a>
Pages
249-255
Issue
2
Volume
94
ISSN
1522-726X
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Update Year & Number
June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Association of peripheral artery disease with in-hospital outcomes after endovascular transcatheter aortic valve replacement.
Publisher
An entity responsible for making the resource available
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-08-01
Creator
An entity primarily responsible for making the resource
Mohananey D; Villablanca PA; Gupta T; Ranka S; Bhatia N; Adegbala O; Ando T; Wang DD; Wiley JM; Eng M; Kalra A; Ramakrishna H; Shah B; O'Neill W; Saucedo J; Bhatt DL
Description
An account of the resource
OBJECTIVES: The aim of this study was to determine the prevalence of peripheral artery disease (PAD) and its association with in-hospital outcomes after endovascular transcatheter aortic valve replacement (EV-TAVR). BACKGROUND: TAVR is an established treatment for patients at prohibitive, high, or intermediate surgical risk. PAD is a significant comorbidity in the determination of surgical risk. However, data on association of PAD with outcomes after EV-TAVR are limited. METHODS: Patients in the National Inpatient Sample who underwent EV-TAVR between January 1, 2012 and September 30, 2015 were evaluated. The primary outcome was in-hospital mortality. RESULTS: A total of 51,685 patients underwent EV-TAVR during the study period. Of these, 12,740 (24.6%) had a coexisting diagnosis of PAD. The adjusted odds for in-hospital mortality [OR 1.08 (95% CI 0.83-1.41)], permanent pacemaker implantation [OR 0.98 (0.85-1.14)], conversion to open aortic valve replacement [OR 1.05 (0.49-2.26)], or acute myocardial infarction [OR 1.31(0.99-1.71)] were not different in patients with versus without PAD. However, patients with PAD had greater adjusted odds of vascular complications [OR 1.80 (1.50-2.16)], major bleeding [OR 1.20 (1.09-1.34)], acute kidney injury (AKI) [OR 1.19 (1.05-1.36)], cardiac complications [aOR 1.21 (1.01-1.44)], and stroke [OR 1.39(1.10-1.75)] compared with patients without PAD. Length of stay (LOS) was significantly longer for patients with PAD [7.23 (0.14) days vs. 7.11 (0.1) days, p < 0.001]. CONCLUSION: Of patients undergoing EV-TAVR, ~25% have coexisting PAD. PAD was not associated with increased risk of in-hospital mortality but was associated with higher risk of vascular complications, major bleeding, AKI, stroke, cardiac complications, and longer LOS.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/ccd.28310" target="_blank" rel="noreferrer noopener">10.1002/ccd.28310</a>
PMID: 31025488
Rights
Information about rights held in and over the resource
© 2019 Wiley Periodicals, Inc.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Adegbala O
Ando T
Bhatia N
Bhatt DL
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Eng M
Gupta T
journalArticle
June2020SubmittedList
Kalra A
Mohananey D
NEOMED College of Medicine
O'Neill W
Ramakrishna H
Ranka S
Saucedo J
Shah B
Villablanca PA
Wang DD
Wiley JM
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.athoracsur.2019.03.080" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.athoracsur.2019.03.080</a>
Pages
1404-1408
Issue
5
Volume
108
ISSN
1552-6259
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Update Year & Number
June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Stability after initial decline in coronary revascularization rates in the united states.
Publisher
An entity responsible for making the resource available
The Annals of thoracic surgery
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-11
Subject
The topic of the resource
Female; Humans; Male; Aged; Middle Aged; United States; Aged 80 and over; Coronary Artery Bypass/statistics & numerical data; Percutaneous Coronary Intervention/statistics & numerical data; Procedures and Techniques Utilization/statistics & numerical data
Creator
An entity primarily responsible for making the resource
Raza S; Deo VS; Kalra A; Zia A; Altarabsheh SE; Deo VS; Mustafa RR; Younes A; Rao SV; Markowitz AH; Park SJ; Costa MA; Simon DI; Bhatt DL; Sabik JF 3rd
Description
An account of the resource
BACKGROUND: It remains uncertain how advances in revascularization techniques, availability of new evidence, and updated guidelines have influenced the annual rates of coronary revascularization in the United States. METHODS: We used the Nationwide Inpatient Sample data from 2005 to 2014 with appropriate weighting to determine national procedural volumes. To present accurately overall percutaneous coronary intervention (PCI) rates, PCI with same-day discharge numbers per year were estimated from the available literature and added to annual PCI procedures performed. RESULTS: Annual PCI rate declined from 353 per 100,000 adults in 2005 to 277 per 100,000 adults in 2009 (P < .001) but remained stable thereafter (P = .50). Annual coronary artery bypass grafting (CABG) rate declined steadily, at a shallower slope than PCI, from 120 per 100,000 in 2005 to 93 per 100,000 in 2009 (P = .02) but remained stable thereafter (P = .60). Similar trends were seen in men and women. Both PCI and CABG rates were lower in women than men over the study period (PCI, 482 to 324/100,000 in men vs 232 to 153/100,000 in women; CABG, 172 to 118/100,000 in men vs 64 to 38/100,000 in women). Annual PCI rates were higher than CABG rates in patients of all age groups including in younger patients (age < 50) and octogenarians. The proportion of coronary revascularization procedures performed per insurance type remained relatively similar across the study period. CONCLUSIONS: Annual rates of coronary revascularization have changed significantly over time, potentially because of advances in revascularization techniques, availability of new evidence, and updated guidelines. Rates of PCI declined more steeply than CABG before plateauing but remained higher than rates of CABG across the study period.
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<a href="http://doi.org/10.1016/j.athoracsur.2019.03.080" target="_blank" rel="noreferrer noopener">10.1016/j.athoracsur.2019.03.080</a>
PMID: 31039350
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Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Format
The file format, physical medium, or dimensions of the resource
journalArticle
2019
Aged
Aged 80 and over
Altarabsheh SE
Bhatt DL
Cleveland Clinic Akron General Hospital
Coronary Artery Bypass/statistics & numerical data
Costa MA
Deo VS
Department of Internal Medicine
Female
Humans
journalArticle
June2020SubmittedList
Kalra A
Male
Markowitz AH
Middle Aged
Mustafa RR
NEOMED College of Medicine
Park SJ
Percutaneous Coronary Intervention/statistics & numerical data
Procedures and Techniques Utilization/statistics & numerical data
Rao SV
Raza S
Sabik JF 3rd
Simon DI
The Annals of thoracic surgery
United States
Younes A
Zia A
-
Text
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<a href="http://doi.org/10.1093/eurheartj/ehz257" target="_blank" rel="noreferrer noopener">http://doi.org/10.1093/eurheartj/ehz257</a>
Pages
1395-1397
Issue
18
Volume
40
ISSN
1522-9645
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
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Cleveland Clinic Akron General Hospital
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Title
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Leadership in cardiovascular medicine.
Publisher
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European heart journal
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-05-07
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Shaikh AA; Bhatt DL; Kalra A
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<a href="http://doi.org/10.1093/eurheartj/ehz257" target="_blank" rel="noreferrer noopener">10.1093/eurheartj/ehz257</a>
PMID: 31506693
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Copyright © 2019 Elsevier Inc. All rights reserved.
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journalArticle
2019
Bhatt DL
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
European Heart Journal
journalArticle
June2020SubmittedList
Kalra A
NEOMED College of Medicine
Shaikh AA
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.carrev.2019.05.012" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.carrev.2019.05.012</a>
Pages
367-374
Issue
3
Volume
21
ISSN
1878-0938 1878-0938
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
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Department of Internal Medicine
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Cleveland Clinic Akron General Hospital
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Title
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Coronary embolism: A systematic review.
Publisher
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Cardiovascular revascularization medicine : including molecular interventions
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-03
Creator
An entity primarily responsible for making the resource
Lacey MJ; Raza S; Rehman H; Puri R; Bhatt DL; Kalra A
Description
An account of the resource
BACKGROUND: Coronary embolism is a rare and potentially fatal phenomenon that occurs primarily in patients with valvular heart disease and atrial fibrillation. There is a lack of consensus regarding the diagnosis, treatment, and management of coronary embolism, leaving management at the discretion of the treating physician. Through this review, we aim to establish a better understanding of coronary embolism, and to identify treatment options - invasive and non-invasive - that may be used to manage coronary embolism. METHODS AND RESULTS: Our systematic review included 147 documented cases of coronary embolism from case reports and case series. The average age of our population was 54.2 ± 17.6 years. The most common causes of coronary embolism included infective endocarditis (22.4%), atrial fibrillation (17.0%), and prosthetic heart valve thrombosis (16.3%). Initial presentation was indistinguishable from an acute coronary syndrome (ACS) due to coronary atherosclerosis, and the diagnosis required a high level of suspicion and evaluation with angiography. Treatment strategies included, but were not limited to, thrombectomy, thrombolysis, balloon angioplasty and stent placement. Myocardial dysfunction on echocardiography was observed in over 80% of patients following coronary embolism. "Good outcomes" were reported in 68.7% of case reports and case series, with a mortality rate of 12.9%. CONCLUSION: Coronary embolism is an under-recognized etiology of myocardial infarction with the potential for significant morbidity and mortality. To improve outcomes, physicians should strive for early diagnosis and intervention based on the underlying etiology. Thrombectomy may be considered with the goal of rapid restoration of coronary flow.
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<a href="http://doi.org/10.1016/j.carrev.2019.05.012" target="_blank" rel="noreferrer noopener">10.1016/j.carrev.2019.05.012</a>
PMID: 31178350
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Copyright © 2019 Elsevier Inc. All rights reserved.
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journalArticle
2020
Bhatt DL
Cardiovascular revascularization medicine : including molecular interventions
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
journalArticle
June2020SubmittedList
Kalra A
Lacey MJ
NEOMED College of Medicine
Puri R
Raza S
Rehman H
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4244/EIJ-D-18-00954" target="_blank" rel="noreferrer noopener">http://doi.org/10.4244/EIJ-D-18-00954</a>
Pages
155-163
Issue
2
Volume
15
ISSN
1969-6213 1774-024X
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
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Department of Internal Medicine
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Cleveland Clinic Akron General Hospital
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Title
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Derivation and external validation of a simple risk tool to predict 30-day hospital readmissions after transcatheter aortic valve replacement.
Publisher
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EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-06-20
Subject
The topic of the resource
Humans; Treatment Outcome; Risk Factors; Time Factors; Aortic Valve; Patient Readmission; Aortic Valve Stenosis; Transcatheter Aortic Valve Replacement
Creator
An entity primarily responsible for making the resource
Khera S; Kolte D; Deo VS; Kalra A; Gupta T; Abbott JD; Kleiman NS; Bhatt DL; Fonarow GC; Khalique OK; Kodali S; Leon MB; Elmariah S
Description
An account of the resource
AIMS: Patients undergoing transcatheter aortic valve replacement (TAVR) possess a higher risk of recurrent healthcare resource utilisation due to multiple comorbidities, frailty, and advanced age. We sought to devise a simple tool to identify TAVR patients at increased risk of 30-day readmission. METHODS AND RESULTS: We used the Nationwide Readmissions Database from January 2013 to September 2015. Complex survey methods and hierarchical regression in R were implemented to create a prediction tool to determine probability of 30-day readmission. Boot-strapped internal validation and cross-validation were performed to assess model accuracy. External validation was performed using a single-centre data set. Of 39,305 patients who underwent endovascular TAVR, 6,380 (16.2%) were readmitted within 30 days. The final 30-day readmission risk prediction tool included the following variables: chronic kidney disease, end-stage renal disease on dialysis (ESRD), anaemia, chronic lung disease, chronic liver disease, atrial fibrillation, length of stay, acute kidney injury, and discharge disposition. ESRD (OR 2.11, 95% CI: 1.7-2.63), length of stay ≥5 days (OR 1.64, 95% CI: 1.50-1.79), and short-term hospital discharge disposition (OR 1.81, 95% CI: 1.2-2.7) were the strongest predictors. The c-statistic of the prediction model was 0.63. The c-statistic in the external validation cohort was 0.69. On internal calibration, the tool was extremely accurate in predicting readmissions up to 25%. CONCLUSIONS: A simple and easy-to-use risk prediction tool utilising standard clinical parameters identifies TAVR patients at increased risk of 30-day readmission. The tool may consequently inform hospital discharge planning, optimise transitions of care, and reduce resource utilisation.
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<a href="http://doi.org/10.4244/EIJ-D-18-00954" target="_blank" rel="noreferrer noopener">10.4244/EIJ-D-18-00954</a>
PMID: 30803938
Rights
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Copyright © 2019. Published by Elsevier Inc.
Format
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journalArticle
2019
Abbott JD
Aortic Valve
Aortic Valve Stenosis
Bhatt DL
Cleveland Clinic Akron General Hospital
Deo VS
Department of Internal Medicine
Elmariah S
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Fonarow GC
Gupta T
Humans
journalArticle
June2020SubmittedList
Kalra A
Khalique OK
Khera S
Kleiman NS
Kodali S
Kolte D
Leon MB
NEOMED College of Medicine
Patient Readmission
Risk Factors
Time Factors
transcatheter aortic valve replacement
Treatment Outcome
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1161/JAHA.119.013246" target="_blank" rel="noreferrer noopener">http://doi.org/10.1161/JAHA.119.013246</a>
Pages
e013246
Issue
19
Volume
8
ISSN
2047-9980
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
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Title
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Association of acute venous thromboembolism with in-hospital outcomes of coronary artery bypass graft surgery.
Publisher
An entity responsible for making the resource available
Journal of the American Heart Association
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-10
Subject
The topic of the resource
venous thrombosis; coronary artery bypass; coronary artery bypass graft surgery; venous thromboembolism
Creator
An entity primarily responsible for making the resource
Panhwar MS; Ginwalla M; Kalra A; Gupta T; Kolte D; Khera S; Bhatt DL; Sabik JF 3rd
Description
An account of the resource
Background While venous thromboembolism (VTE) prophylaxis is a strong recommendation after most surgeries, it is controversial in cardiac surgeries such as coronary artery bypass grafting (CABG), because of perceived low VTE incidence and increased bleeding risk. Prior studies may not have been adequately powered to study outcomes of VTE in this population. We sought to investigate the postoperative incidence and outcomes of CABG patients using a large national inpatient database. Methods and Results We utilized the 2013 to 2014 National Inpatient Sample to identify all patients >18 years of age who underwent CABG (without concomitant valvular procedures), and had VTE during the hospital stay. We then compared clinically relevant outcomes in patients with and without VTE. We identified 331 950 CABG procedures. Of these, 1.3% (n=4205) had VTE. Patients with VTE were more likely to be older (mean 67.2±10.4 years versus 65.2±10.4 years, P<0.001). VTE was associated with higher incidence of inpatient mortality (6.8% versus 1.7%; adjusted odds ratio 1.92 [95% CI 1.40-2.65]; P<0.001) and complications. VTE was also associated with higher cost (mean±SE $81 995±$923 versus $48 909±$55) and longer length of stay (mean±SE 17.06±0.16 days versus 8.52±0.01 days). Conclusions Our analysis of >330 000 CABG procedures suggests that while postoperative VTE after CABG is rare, it is associated with increased morbidity and mortality. Randomized controlled trials are needed to identify optimal strategies for VTE prophylaxis in these patients.
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<a href="http://doi.org/10.1161/JAHA.119.013246" target="_blank" rel="noreferrer noopener">10.1161/JAHA.119.013246</a>
PMID: 31533551
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Copyright © 2019. Published by Elsevier Inc.
Format
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journalArticle
2019
Bhatt DL
Cleveland Clinic Akron General Hospital
Coronary Artery Bypass
Coronary artery bypass graft surgery
Department of Internal Medicine
Ginwalla M
Gupta T
Journal of the American Heart Association
journalArticle
June2020SubmittedList
Kalra A
Khera S
Kolte D
NEOMED College of Medicine
Panhwar MS
Sabik JF 3rd
Venous thromboembolism
Venous Thrombosis
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/j.athoracsur.2019.08.023" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.athoracsur.2019.08.023</a>
ISSN
1552-6259 0003-4975
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June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
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Title
A name given to the resource
Aortic valve replacement in bioprosthetic failure:Insights from the society of thoracic surgeons national database.
Publisher
An entity responsible for making the resource available
The Annals of thoracic surgery
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-09-23
Creator
An entity primarily responsible for making the resource
Kalra A; Raza S; Hussain M; Shorbaji K; Delozier S; Deo VS; Khera S; Kleiman NS; Reardon MJ; Kolte D; Gupta T; Mustafa RR; Bhatt DL; Sabik JF 3rd
Description
An account of the resource
BACKGROUND: To determine the current nationwide trends and outcomes of reoperative surgical aortic valve replacement (SAVR) performed for degenerated bioprosthesis. METHODS: The study was conducted using data from the Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database. All patients who had isolated reoperative SAVR for a degenerated aortic bioprosthesis between January 2012 and December 2016 were included. Patients who had other concomitant cardiac surgery procedures or active endocarditis were excluded. Trend analyses were conducted to track changes during this time period. RESULTS: The number of patients undergoing SAVR for bioprosthetic failure increased substantially between 2012 and 2014 (782 in 2012 to 844 in 2013 and 900 in 2014; relative change = +7.25%); this trend reversed significantly between 2015 and 2016 (decreased to 873 in 2015 and 840 in 2016; relative change = -3.4%, P= 0.005). Patients were older in 2012-2014 (65.80 ± 13.52 years) compared with 2015-2016 (64.45 ± 12.91 years; P= 0.001). Mean STS-predicted mortality risk score decreased from 4.55% in 2012-2014 to 4.25% in 2015-2016 (P = 0.001). There was no difference in post-operative stroke (1.80% vs. 1.80%, P= 0.87), renal failure requiring dialysis (2.7% vs. 2.8%, P= 0.69), or operative mortality (3.5% vs. 4.0%, P= 0.36) after reoperative SAVR in 2012-2014 and 2015-2016, respectively. CONCLUSIONS: The number of patients undergoing SAVR for degenerated bioprosthesis is decreasing in U.S, particularly among older and high-risk patients. These trends may reflect the adoption of valve-in-valve transcatheter aortic valve replacement for degenerated bioprosthesis after its FDA approval in 2015.
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<a href="http://doi.org/10.1016/j.athoracsur.2019.08.023" target="_blank" rel="noreferrer noopener">10.1016/j.athoracsur.2019.08.023</a>
PMID: 31557477
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Copyright © 2019. Published by Elsevier Inc.
Format
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journalArticle
2019
Bhatt DL
Cleveland Clinic Akron General Hospital
Delozier S
Deo VS
Department of Internal Medicine
Gupta T
Hussain M
journalArticle
June2020SubmittedList
Kalra A
Khera S
Kleiman NS
Kolte D
Mustafa RR
NEOMED College of Medicine
Raza S
Reardon MJ
Sabik JF 3rd
Shorbaji K
The Annals of thoracic surgery
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.4244/EIJ-D-19-00381" target="_blank" rel="noreferrer noopener">http://doi.org/10.4244/EIJ-D-19-00381</a>
Pages
e968-e974
Issue
11
Volume
15
ISSN
1969-6213 1774-024X
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Update Year & Number
June2020SubmittedList
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
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Title
A name given to the resource
The changing landscape of aortic valve replacement in the usa.
Publisher
An entity responsible for making the resource available
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
2019-12-06
Subject
The topic of the resource
Adolescent; Female; Humans; Male; Adult; Aged; Treatment Outcome; Risk Factors; United States; Aged 80 and over; Aortic Valve; Aortic Valve Stenosis; Transcatheter Aortic Valve Replacement
Creator
An entity primarily responsible for making the resource
Gupta T; Kolte D; Khera S; Goel K; Villablanca PA; Kalra A; Abbott JD; Elmariah S; Fonarow GC; Rihal CS; Garcia MJ; Weisz G; Bhatt DL
Description
An account of the resource
AIMS: The aim of this study was to analyse the real-world national data on parallel utilisation of transcatheter (TAVR) and surgical (SAVR) aortic valve replacement. METHODS AND RESULTS: We queried an all-payer, administrative United States in-patient database to identify all AVR hospitalisations in patients aged ≥18 years from January 2012 to December 2016 and examined the temporal changes in the number of AVR procedures and in-hospital mortality. A total of 463,675 AVRs were performed - 363,275 (78.4%) SAVR and 100,400 (21.6%) TAVR. AVR linearly increased (from 78,985 in 2012 to 103,415 in 2016; +30.9%; ptrend<0.001) largely due to a marked increase in TAVR (from 7,655 to 33,545; +338%; ptrend<0.001), whereas the absolute number of SAVRs remained relatively stable (from 71,330 to 69,870; -1%; ptrend<0.001). The number of TAVRs increased in all pre-specified age groups (<75, 75-79, 80-85, and ≥85 years; ptrend<0.001 for all). In contrast, the number of SAVRs increased modestly in patients aged <75 years (ptrend<0.001) and declined in those aged 75-79 years, 80-84 years, or ≥85 years (ptrend<0.001 for all). Age- and sex-adjusted in-hospital mortality after isolated (aOR 1.00 [0.95-1.05]; ptrend=0.96) or combined SAVR (aOR 1.01 [0.97-1.05]; ptrend=0.66) remained unchanged during the study period, whereas in-hospital mortality after TAVR declined (aOR 0.75 [0.70-0.79]; ptrend<0.001). Similar trends in in-hospital mortality were seen in the age subgroups. CONCLUSIONS: The number of AVRs markedly increased in the USA from 2012 to 2016, mainly due to the widespread adoption of TAVR, whereas the number of SAVRs remained relatively stable. In-hospital mortality after TAVR declined, whereas that after SAVR has remained unchanged.
Identifier
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<a href="http://doi.org/10.4244/EIJ-D-19-00381" target="_blank" rel="noreferrer noopener">10.4244/EIJ-D-19-00381</a>
PMID: 31403460
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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journalArticle
2019
Abbott JD
Adolescent
Adult
Aged
Aged 80 and over
Aortic Valve
Aortic Valve Stenosis
Bhatt DL
Cleveland Clinic Akron General Hospital
Department of Internal Medicine
Elmariah S
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Female
Fonarow GC
Garcia MJ
Goel K
Gupta T
Humans
journalArticle
June2020SubmittedList
Kalra A
Khera S
Kolte D
Male
NEOMED College of Medicine
Rihal CS
Risk Factors
transcatheter aortic valve replacement
Treatment Outcome
United States
Villablanca PA
Weisz G