SYNTHESIS OF ESTERS OF TETRADECANOIC ACID DEUTERATED AT THE PENULTIMATE CARBON - SOME GENERAL PROCEDURES FOR THE SYNTHESIS OF SELECTIVELY DEUTERATED FATTY-ACIDS
Biochemistry & Molecular Biology; Biophysics
Westerman P W; Ghrayeb N
Chemistry and Physics of Lipids
1982
1982
Journal Article
<a href="http://doi.org/10.1016/0009-3084(82)90031-7" target="_blank" rel="noreferrer noopener">10.1016/0009-3084(82)90031-7</a>
Oculocutaneous Albinism in Sub-Saharan Africa: Adverse Sun-Associated Health Effects and Photoprotection
Biochemistry & Molecular Biology; Biophysics; care; children; community; Nigeria; northern tanzania; population; program; skin cancer; southern-africa; zimbabwe
Oculocutaneous albinism (OCA) is a genetically inherited autosomal recessive condition. Individuals with OCA lack melanin and therefore are susceptible to the harmful effects of solar ultraviolet radiation, including extreme sun sensitivity, photophobia and skin cancer. OCA is a grave public health issue in sub-Saharan Africa with a prevalence as high as 1 in 1000 in some tribes. This article considers the characteristics and prevalence of OCA in sub-Saharan African countries. Sun-induced adverse health effects in the skin and eyes of OCA individuals are reviewed. Sun exposure behavior and the use of photoprotection for the skin and eyes are discussed to highlight the major challenges experienced by these at-risk individuals and how these might be best resolved.
Wright C Y; Norval M; Hertle R W
Photochemistry and Photobiology
2015
2015-01
Journal Article
<a href="http://doi.org/10.1111/php.12359" target="_blank" rel="noreferrer noopener">10.1111/php.12359</a>
RNAi knockdown of Par-4 inhibits neurosynaptic degeneration in ALS-linked mice
amyotrophic lateral sclerosis; amyotrophic lateral sclerosis; anterior horn; antisense oligonucleotides; apoptosis; apoptosis response-4; Biochemistry & Molecular Biology; cells; Cu/Zn superoxide dismutase; motor-neuron degeneration; neurons; Neurosciences & Neurology; prostate; protein; RNA interference; sod1; spinal motor neurons; synapse; synapses; transgenic mouse model
Evidence from human amyotrophic lateral sclerosis (ALS) patients and ALS-linked Cu/Zn superoxide dismutase (Cu/Zn-SOD) transgenic mice bearing the mutation of glycine to alanine at position 93 (G93A) suggests that the pro-apoptotic protein prostate apoptosis response-4 (Par-4) might be a critical link in the chain of events leading to motor neuron degeneration. We now report that Par-4 is enriched in synaptosomes and post-synaptic density from the ventral horn of the spinal cord. Levels of Par-4 in synaptic compartments increased significantly during rapid and slow declining stages of muscle strength in hSOD1 G93A mutant mice. In the pre-muscle weakness stage, hSOD1 G93A mutation sensitized synaptosomes from the ventral horn of the spinal cord to increased levels of Par-4 expression following excitotoxic and apoptotic insults. In ventral spinal synaptosomes, Par-4-mediated production of pro-apoptotic cytosolic factor(s) was significantly enhanced by the hSOD1 G93A mutation. RNA interference (RNAi) knockdown of Par-4 inhibited mitochondrial dysfunction and caspase-3 activation induced by G93A mutation in synaptosomes from the ventral horn of the spinal cord, and protected spinal motor neurons from apoptosis. These results identify the synapse as a crucial cellular site for the cell death promoting actions of Par-4 in motor neurons, and suggest that targeted inhibition of Par-4 by RNAi may prove to be a neuroprotective strategy for motor neuron degeneration.
Xie J; Awad K S; Guo Q
Journal of Neurochemistry
2005
2005-01
Journal Article
<a href="http://doi.org/10.1111/j.1471-4159.2004.02834.x" target="_blank" rel="noreferrer noopener">10.1111/j.1471-4159.2004.02834.x</a>
Hepatic Carboxylesterase 1 is Essential for Both Normal and Farnesoid X Receptor-Controlled Lipid Homeostasis
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Xu J S; Li Y Y; Xu Y
Faseb Journal
2015
2015-04
Journal Article
<a href="http://doi.org/10.1002/hep.26714" target="_blank" rel="noreferrer noopener">10.1002/hep.26714</a>
DOPAMINERGIC MODULATION OF GLUTAMATE RELEASE IN STRIATUM AS MEASURED BY MICRODIALYSIS
afferents; amino-acid neurotransmitters; aspartate; Biochemistry & Molecular Biology; brain-tissue; corticostriatal path; d2 receptors; dopamine; endogenous glutamate; glutamate; in-vivo; lesion; microdialysis; nerve-terminals; Neurosciences & Neurology; pathway; rat caudate-putamen
Glutamate and aspartate are the primary neurotransmitters of projections from motor and premotor cortices to the striatum. Release of glutamate may be modulated by dopamine receptors located on corticostriatal terminals. The present study used microdialysis to investigate the dopaminergic modulation of in vivo striatal glutamate and aspartate release in the striatum of awake-behaving rats. Local perfusion with a depolarizing concentration of K+ through a dialysis probe into the rat striatum produced a significant increase in the release of glutamate, aspartate, and taurine. The D2 agonist LY171555 blocked the K+-induced release of glutamate and aspartate, but not taurine, in a concentration-dependent manner. The D1 agonist SKF 38393 did not alter K+-induced release of glutamate and taurine, but did significantly decrease aspartate release. Neither agonist had any effect on basal amino acid release. The D2 antagonist (-)-sulpiride reversed the inhibitory effects of LY 171555 on K+-induced glutamate release. These results provide in vivo evidence for a functional interaction between dopamine, the D2 receptor, and striatal glutamate release.
Yamamoto B K; Davy S
Journal of Neurochemistry
1992
1992-05
Journal Article
<a href="http://doi.org/10.1111/j.1471-4159.1992.tb10048.x" target="_blank" rel="noreferrer noopener">10.1111/j.1471-4159.1992.tb10048.x</a>
BAG-1 modulates endoplasmic reticulum stress in chondrocytes
Biochemistry & Molecular Biology; Cell Biology
Yang L; Carlson S G; McBurney D; Horton W E
Matrix Biology
2006
2006-11
Journal Article
<a href="http://doi.org/10.1016/j.matbio.2006.08.195" target="_blank" rel="noreferrer noopener">10.1016/j.matbio.2006.08.195</a>
On the mechanism of bile acid inhibition of rat sterol 12 alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4 alpha
activation; bile acid synthesise; Biochemistry & Molecular Biology; Biophysics; biosynthesis; Cell Biology; cholesterol 7-alpha-hydroxylase gene; Cyp7a1; cytochrome P450; expression; feedback-regulation; gene regulation; liver microsomal metabolism; nuclear receptor; promoter; receptor; repression
The sterol 12alpha-hydroxylase (CYP8B1) is a key enzyme of the bile acid biosynthetic pathway. It regulates the composition of bile acids in bile, i.e. ratio between cholic acid (CA) and chenodeoxycholic acid (CDCA). In similarity with cholesterol 7alpha-hydroxylase (CYP7A1), this enzyme is subjected to a negative feedback regulation by bile acids, It has been recently reported that bile acid-activated famesoid X receptor (FXR) induces the small heterodimer partner (SHP) that interacts with alpha-fetoprotein transcription factor (FTF) and down-regulates CYP7A1 transcription. We studied whether the same mechanism also regulated rat CYP8B1 gene transcription. Feeding rats with CDCA caused a 40-50% decrease of CYP8B1 and hepatocyte nuclear factor 4alpha (HNF4alpha) mRNA expression levels. This was associated with an increase in FTF mRNA expression, but SHP mRNA expression was not altered. Electrophoretic mobility shift assay (EMSA) and transient transfection assay of promoter/reporter genes coupled to mutagenesis analysis identified a putative bile acid response element (BARE) that has an HNF4alpha binding site embedded in two overlapping FTF binding sites. Mutation of the HNF4alpha binding site markedly reduced basal promoter activity and its repression by bile acids. Cotransfection with FTF strongly repressed CYP8B1 transcription. Interestingly, HNF4alpha could overcome the inhibitory effects of FTF and bile acids. We conclude that FTF and HNF4alpha not only play critical roles on CYP8B1 gene transcription, but also mediate bile acid feedback inhibition. This study reveals a novel mechanism by which bile acids inhibit rat CYP8B1 gene transcription by inducing FTF and inhibiting HNF4alpha expression. (C) 2002 Elsevier Science B.V. All rights reserved.
Yang Y Z; Zhang M; Eggertsen G; Chiang J Y L
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids
2002
2002-06
Journal Article
<a href="http://doi.org/10.1016/s1388-1981(02)00186-5" target="_blank" rel="noreferrer noopener">10.1016/s1388-1981(02)00186-5</a>
Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12 alpha-hydroxylase gene (CYP8B1)
bile acids; bile-acid metabolism; Biochemistry & Molecular Biology; Biophysics; cholesterol; CYP8B1; gene regulation; liver; mice; mouse; pathway; promoter; rat; receptor lxr-alpha; SREBP; srebps; suppresses
Sterol 12alpha-hydroxylase (CYP8B1) is an obligatory enzyme for the synthesis of cholic acid and regulation of liver bile acid synthesis and intestine cholesterol absorption. The present study evaluates the roles for sterol regulatory element binding proteins (SREBPs) in the regulation of the CYP8B1 gene. Cholesterol feeding of mice and rats decreased the activity of CYP8B1, contrary to the up-regulation of cholesterol 7alpha-hydroxylase (CYP7A1). Cholesterol feeding also reduced mRNA levels for SREBP-1 but not for SREBP-2 in rat livers. Cholesterol and 25-hydroxycholesterol decreased the CYP8B1/luciferase reporter activity. Co-transfection of SREBP-1a and -1c stimulated CYP8B1 promoter activity, while SREBP-2 did not have any effects. Electrophoretic mobility shift assay and mutagenesis analyses identified several functional sterol regulatory elements (SRE) and E-box motifs in the rat CYP8B1 promoter. Our results indicate that SREBP-1a and -1c enhance transcription of the CYP8B1 gene through binding to SRE. Cholesterol loading reduces SREBP-1 mRNA expression in addition to reducing functional SREBP-1 protein, and results in decreasing CYP8B1 gene transcription. (C) 2004 Elsevier Inc. All rights reserved.
Yang Y Z; Eggertsen G; Gafvels M; Andersson U; Einarsson C; Bjorkhem I; Chiang J Y L
Biochemical and Biophysical Research Communications
2004
2004-08
Journal Article
<a href="http://doi.org/10.1016/j.bbrc.2004.06.069" target="_blank" rel="noreferrer noopener">10.1016/j.bbrc.2004.06.069</a>
Simplified method for concentration of mitochondrial membrane protein complexes
Biochemistry & Molecular Biology; blue; Blue native PAGE; Chemistry; Complex I; Electrophoretic concentration; Mitochondria; native electrophoresis; oxidative-phosphorylation; polyacrylamide-gels; sds-page
Extracting and concentrating mitochondrial protein complexes from gel strips after blue native PAGE (BN-PAGE) can be daunting tasks using the traditional methods, such as electroelution, passive diffusion and centrifugal concentration. We present a simplified gel electrophoresis method to concentrate mitochondrial protein complexes with excellent recovery rate. Mitochondrial complex I present in a long gel strip from BN-PAGE can be easily concentrated into a 0.8 cm gel strip when a second BN-PAGE is performed with a Y-shaped gel and the addition of 0.01% n-dodecyl beta-D-maltoside and 0.001% SDS in the cathode buffer. Once completed, the concentrated protein complex in the gel strip is ready for SDS-PAGE or proteomic studies.
Yeh S T; Angelos M G; Chen Y R
Electrophoresis
2010
2010-06
Journal Article
<a href="http://doi.org/10.1002/elps.201000019" target="_blank" rel="noreferrer noopener">10.1002/elps.201000019</a>
THE CHARACTERIZATION OF 3 TYPES OF PARTIALLY PROCESSED MESSENGER-RNA AND 2 PSEUDOGENES FOR HUMAN-LIVER CYTOCHROME-B5
Biochemistry & Molecular Biology; Biophysics
Yoo M; Steggles A W
Biochemical and Biophysical Research Communications
1989
1989-08
Journal Article
<a href="http://doi.org/10.1016/0006-291x(89)92092-5" target="_blank" rel="noreferrer noopener">10.1016/0006-291x(89)92092-5</a>
THE COMPLETE NUCLEOTIDE-SEQUENCE OF HUMAN-LIVER CYTOCHROME-B5 MESSENGER-RNA
Biochemistry & Molecular Biology; Biophysics
Yoo M; Steggles A W
Biochemical and Biophysical Research Communications
1988
1988-10
Journal Article
<a href="http://doi.org/10.1016/s0006-291x(88)80881-7" target="_blank" rel="noreferrer noopener">10.1016/s0006-291x(88)80881-7</a>
Peroxynitrite-Mediated Oxidative Modifications of Complex II: Relevance in Myocardial Infarction
Biochemistry & Molecular Biology; cytochrome-c; fatty-acids; identification; membrane; mitochondrial; modulation; nitric-oxide; postischemic heart; succinate-ubiquinone; thiyl
Increased O-2(center dot-) and NO production is a key mechanism of mitochondrial dysfunction in mycocardial ischemia/reperfusion injury. In complex impairment and enhanced tyrosine nitration of the 70 kDa FAD-binding protein occur in the post-ischemic myocardium and are thought to be mediated by peroxynitrite (OONO-) ill vivo [Chen, Y.-R., et ill. (2008) J. Biol. Chem. 283, 27991-28003]. To gain deeper insights into the redox protein thiols involved ill OONO--mediated Oxidative post-translational modifications relevant ill myocardial infarction, We subjected Isolated myocardial complex 11 to ill vltro protein nitration with OONO-. This resulted ill site-specific nitration at the 70 kDa polypeptide and impairment of complex II-derived electron transfer activity. Under reducing conditions, the gel band of the 70 kDa POlyPePtldC MIS subjected to in-gel trypsin/chymotrypsin digestion and then LC-MS/MS analysis Nitration Of Y-56 and Y-142 was previosly reported. Further analysis revealed that C-267, C-476 and C-537 are involved ill OONO--mediated S-sulfonation. To identify the disulfide formation mediated by OONO-, nitrated complex 11 was alkylated with iodoacetamide. In-gel proteolytic digestion and LC-MS/MS analysis were conducted under nonreducing conditions. The MS/MS data were examined with MassMatrix, indicating that three cysteine pairs, C-306-C-312,C-439-C-444, and C-288-C-575, were involved in OONO--mediated disulfide formation. Immuno-spin trapping with an anti-DMPO antibody and subsequent MS Was used to define Oxidative modification with protein radical formation. An OONO--dependent DMPO adduct was detected. and further LC-MS/MS analysis indicated C-288 and C-655 were involved in DMPO binding. These I-CSLIltS offered a complete profile of OONO--mediated Oxidative modifications that may be relevant Ill the disease model of myocardial infarction.
Zhang L W; Chen C L; Kang P T; Garg V; Hu K L; Green-Church K B; Chen Y R
Biochemistry
2010
2010-03
Journal Article
<a href="http://doi.org/10.1021/bi9018237" target="_blank" rel="noreferrer noopener">10.1021/bi9018237</a>
The LEAPS approach to vaccine development
beta-2-microglobulin; binding-site; Biochemistry & Molecular Biology; Cell Biology; class-ii molecules; dc; dendritic cells; flt3 ligand fl; herpes simplex virus; HIV; human; immune responses; in-vivo; LEAPS constructs; major histocompatibility complex; peptide; protection; review; t-lymphocytes; th1 immune-responses; vaccines
The Ligand Epitope Antigen Presentation System ( L. E. A. P. S. TM) approach to vaccine development utilizes immune peptides to promote the immunogenicity and influence the type of immune response generated towards epitopes in peptides which may be too small to elicit an immune response. The covalent attachment of these immune peptides to the antigenic peptide promotes the interaction of the epitope with T cells ( T cell binding ligand (TCBL)) or antigen presenting cells ( immune cell binding ligand (ICBL)) and ultimately promotes binding with the T cell receptor on CD4 or CD8 T cells. The "J" ICBL/TCBL peptide derived from the beta-2-microglobulin chain of MHC I molecules promotes Th1 type responses to the antigenic peptide while the "G" ICBL/TCBL peptide derived from the beta chain of MHC II molecules promotes Th2 types of responses. The efficacy of this approach has been demonstrated by characterization of the immune responses to L. E. A. P. S. vaccines and by elicitation of protection from infectious challenge with herpes simplex virus and other pathogens. The protection studies show that the L. E. A. P. S. approach allows customization of the immune response appropriate for inducing protection from disease. The theory, background, examples and studies of the mechanism of action of the L. E. A. P. S. vaccines will be discussed.
Zimmerman D H; Rosenthal K S
Frontiers in Bioscience
2005
2005-01
Journal Article
<a href="http://doi.org/10.2741/1572" target="_blank" rel="noreferrer noopener">10.2741/1572</a>
Comparative analysis of masticatory apparatus features in neonatal common marmosets (Callithrix jacchus) and cotton-top tamarins (Saguinus oedipus)
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Mork A L; Taylor A B; Vinyard C J
Faseb Journal
2012
2012-04
Journal Article
n/a
Genome-wide delineation of VEGF-related genes in the cervix of pregnant rats reveal unexpected candidates
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Mowa C N; Li T; Folkesson H; Lopez M; Jesmin S; Usip S; Papka R; Smith D
Faseb Journal
2006
2006-03
Journal Article
n/a
Micellar nanocontainer polymer, pluronic blocker co-polymer, delivers locally-confined VEGF siRNA to the cervix of pregnant rat
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Mowa C N; Li T; Folkesson H; Lopez M; Jesmin S; Usip S; Papka R; Smith D
Faseb Journal
2006
2006-03
Journal Article
n/a
Angiotensin II enhances beta-adrenergic signaling in cardiac fibroblasts via Gq/Gs cross-talk
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Naugle J E; Zhang X J; Meszaros J G
Faseb Journal
2002
2002-03
Journal Article
n/a
Angiotensin II potentiates signaling via Ca2+-dependent activation of adenylyl cyclase in rat cardiac fibroblasts
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Naugle J E; Zhang X J; Hase M; Ostrom R S; Meszaros J G
Faseb Journal
2003
2003-03
Journal Article
n/a
Growth and differentiation of cardiac fibroblasts and myoribroblasts: regulation by collagen types I, III and cyclic AMP
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Naugle J E; Olson E R; Zhang X J; Mase S; Doane K J; Meszaros J G
Faseb Journal
2004
2004-03
Journal Article
n/a
NITRIC OXIDE-MEDIATED SEX-DIFFERENCES IN VASCULAR REACTIVITY TO VASOPRESSIN DO NOT OCCUR IN ANDROGEN RECEPTOR-DEFICIENT RATS
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Navarro E F; Salisbury R L; Stallone J N
Faseb Journal
1995
1995-03
Journal Article
n/a
Store-operated Ca2+influx predicts coronary artery disease and is induced by dyslipidemia in metabolic syndrome and type 2 diabetes
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Neeb Z P; Alloosh M; Edwards J; Bratz I N; Sturek M
Faseb Journal
2010
2010-04
Journal Article
n/a
Distribution of beta(2)-adrenoceptors (beta(2)ARs) in the alveolar septum of the rat
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Nicholson D J; Papka R E; Maron M B
Faseb Journal
2000
2000-03
Journal Article
n/a
DOES VP-16 DEPLETE PULMONARY INTRAVASCULAR MONONUCLEAR PHAGOCYTES (PMMP)
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Niehaus G D; Karve S
Faseb Journal
1994
1994-03
Journal Article
n/a
Increased monocyte CD11b and CD62L expression in acute respiratory distress syndrome (ARDS) patients
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Niehaus G D; Dunham C M; Dorian K; Pitt T; Khanna K; Fagan D
Faseb Journal
2000
2000-03
Journal Article
n/a
MECHANISMS OF EDEMA FORMATION FOLLOWING LUNG LOCALIZATION OF BLOOD-BORNE PARTICULATES IN SHEEP
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Niehaus G D; Dibattiste D; Swoboda R
Faseb Journal
1988
1988-03
Journal Article
n/a
MICROBIAL PRODUCTS CAN INCREASE THE NUMBER OF RAT LUNG VASCULAR PHAGOCYTES
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Niehaus G D; Karve S V; Mullens D L; Dehring D J
Faseb Journal
1992
1992-02
Journal Article
n/a
USE OF FLOW-CYTOMETRY TO PHENOTYPE RAT PULMONARY INTRAVASCULAR MACROPHAGES
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Niehaus G D; Parker J; Bender J; Shank D; Rosenthal K
Faseb Journal
1991
1991-03
Journal Article
n/a
Transcriptional regulation of human oxysterol 7 alpha-hydroxylase (CYP7B1) by sterol response element binding protein (SREBP) and alpha-fetoprotein transcription factor (FTF)
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Norlin M; Chiang J Y L
Faseb Journal
2003
2003-03
Journal Article
n/a
The effects of aging on peripheral nerve injury induced thermal hyperalgesia and tactile-evoked allodynia
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Novak J C; Lovell J A; Bailey C M; Stuesse S L; Cruce W L R; Crisp T
Faseb Journal
1999
1999-03
Journal Article
n/a
Cardiac Phenotypic Differences in Rat Models of the Metabolic Syndrome
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V; Pung Y F; Hafemeister J L; Hodnichak C; Kolz C; Chilian W M
Faseb Journal
2009
2009-04
Journal Article
n/a
Catecholamine Induced Takotsubo Cardiomyopathy: The role of coronary metabolic blood flow regulation in apical ballooning
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V; Yin L; Bardakjian R; Khayata M; Kolz C L; Enrick M; Schatmeyer B; Perera V; Janota D; Hakobyan T; Chilian W M
Faseb Journal
2016
2016-04
Journal Article
n/a
Gender differences in cardiac function of Kv1.5-/- mice during aging
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V; Yin L Y; Logan S; Enrick M; Hakobyan T; Kolz C L; Pung Y F; Bratz I; Chilian W
Faseb Journal
2012
2012-04
Journal Article
n/a
Role of Arterial TRPV1 Channels in Metabolic Syndrome
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V A; Shamheart P E; Guarini G; Talasila P K; Bratz I N
Faseb Journal
2010
2010-04
Journal Article
n/a
The Role of Potassium Voltage Gated Kv 1.2 Channels in Coronary Metabolic Dilatation
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V A; Bratz I N; Kolz C L; Guarini G; Luther D J; Yin L Y; Pung Y F; Chilian W M
Faseb Journal
2011
2011-04
Journal Article
n/a
Role of Kv 1.5 Channels in Regulation of Myocardial Oxygen Balance
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Ohanyan V; Yin L Y; Enrick M; Nagane M; Hou H G; Hakobyan T; Kolz C; Kuppusamy P; Chilian W
Faseb Journal
2015
2015-04
Journal Article
n/a
MONOAMINE-ACTIVATED ALPHA(2)-MACROGLOBULIN INHIBITS NGF-PROMOTED C-FOS, TRANSIN AND SCG10 EXPRESSIONS IN PHEOCHROMOCYTOMA PC12 CELLS
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Oiu W S; Koo P H
Faseb Journal
1995
1995-03
Journal Article
n/a
Angiotensin II-induced cardiac fibroblast proliferation and ERK 1/2 activation is mediated by PKC zeta
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Olson E R; Naugle J E; Meszaros J G
Faseb Journal
2006
2006-03
Journal Article
n/a
Direct effects of resveratrol on cardiac fibroblasts: inhibition of calcium signaling, MAPK activation, and cellular growth
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Olson E R; Zhang X J; Marsh L; Meszaros J G; Bomser J A
Faseb Journal
2003
2003-03
Journal Article
n/a
Effects of resveratrol on cardiac fibroblasts: inhibition of MAPK regulated proliferation and myofibroblast differentiation
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Olson E R; Naugle J E; Zhang X J; Bomser J A; Meszaros J G
Faseb Journal
2004
2004-03
Journal Article
n/a
Opposing roles of alpha- and beta-adrenergic receptors in cardiac fibroblast differentiation
Biochemistry & Molecular Biology; Cell Biology; Life Sciences & Biomedicine - Other; Topics
Olson E R; Naugle J E; Kiraly F; Zhang X J; Meszaros J G
Faseb Journal
2005
2005-03
Journal Article
n/a