Browse Items · NEOMED Bibliography Database

Acute exercise attenuates cardiac autonomic regulation in hypertensive rats.

Dynamic exercise may be used as a safe, therapeutic approach to reduce sympathetic nerve activity at rest and thus may be beneficial for individuals with hypertension. Therefore, we tested the hypothesis that a single bout of mild to moderate dynamic…

Attenuation of postexertional hypotension by cardiac afferent blockade.

Naloxone eliminates postexertional hypotension (PEH) in human and animal models. The effect of naloxone on sympathetic activity during hemorrhage and generation of arterial baroreflex function curves can be stimulated by blockade of cardiac afferent…

Tags: *Heart Arrest, *Physical Exertion, 1993, Afferent Pathways/physiology, Animals, Blood Pressure/drug effects, Collins H L, DiCarlo S E, Efferent Pathways/physiology, Heart Rate/drug effects, Hypotension/*physiopathology, Inbred SHR, Induced, Pressoreceptors/drug effects, Procainamide/pharmacology, Rats, Reference Values, The American journal of physiology

Hemodynamic basis for cocaine-induced pulmonary edema in dogs.

We tested the hypothesis that cocaine-induced impairment of left ventricular function results in cardiogenic pulmonary edema. Mongrel dogs, anesthetized with alpha-chloralose, were injected with two doses of cocaine (5 mg/kg iv) 27 min apart. Cocaine…

Tags: 1991, Animals, Blood Pressure/drug effects, Cardiac Output/drug effects, Cocaine/*toxicity, Coronary Circulation/drug effects, Dogs, Female, Heart Rate/drug effects, Hemodynamics/*drug effects, Journal of applied physiology (Bethesda, Md. : 1985), Lang S A, Male, Maron M B, Pulmonary Circulation/drug effects, Pulmonary Edema/chemically induced/*physiopathology, Stroke Volume/drug effects, Vascular Resistance/drug effects

Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine.

The influence of the release of endothelium-derived nitric oxide (NO) on the vasoconstrictor response to phenylephrine (PE) was evaluated before and after a single bout of dynamic exercise. Each rat ran on a motor-driven treadmill at

Effect of intracoronary infusion of histamine or compound 48/80 on coronary vascular permeability and myocardial fluid balance.

This study was undertaken to determine if coronary vascular permeability (CVP) increases and if myocardial edema develops in the canine heart after local exposure to histamine. Histamine (50 or 15 micrograms/min) or compound 48/80 (0.1-0.2 mg/kg) was…

Tags: 1991, Animals, Blood Pressure/drug effects, Coronary Circulation/*drug effects, Dogs, Female, Histamine/*administration & dosage, Infusions, Intra-Arterial, Lymph/drug effects, Male, Microvascular research, Myocardium/*metabolism, p-Methoxy-N-methylphenethylamine/*administration & dosage, Pilati C F, Water-Electrolyte Balance/*drug effects

Persistent left ventricular dysfunction after cocaine treatment in rabbits.

The present study was undertaken to determine whether the diminished cardiac performance associated with cocaine administration persists after the drug has been eliminated from the body. Cocaine (5 or 10 mg/kg iv) was administered to conscious (n =…

Mesenteric vascular responses to vasopressin during development of DOCA-salt hypertension in male and female rats.

Deoxycorticosterone acetate (DOCA)-salt hypertension develops to a greater extent in male (M) than in female (F) rats. To determine the role of the vasculature, reactivity to arginine vasopressin (AVP) and prostanoid output were examined in the…

Aspirin attenuation of alcohol-induced flushing and intoxication in Oriental and Occidental subjects.

Aspirin (ASA) was tested in a group of 8 Oriental and 3 Occidental subjects who were shown in a previous study to respond to small doses of ethanol (0.06-0.25 g/kg) with facial flushing. They were compared to a similar group of 11 non-flushing…

Tags: *Alcoholic Intoxication, 1987, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, Asian Continental Ancestry Group, Aspirin/*pharmacology, Blood Pressure/drug effects, Ethanol/*antagonists & inhibitors/pharmacology, European Continental Ancestry Group, Flushing/*chemically induced, Gaynor C R, Heart Rate/drug effects, Humans, Mehl D L, Skin Temperature/drug effects, Truitt E B Jr

Remission of nephrotic syndrome in type 1 diabetes: long-term follow-up of patients in the Captopril Study.

In 1994, we reported a 3.4 +/- 0.8 year follow-up of the eight patients who experienced remission of nephrotic syndrome during the Collaborative Study Group-sponsored, multicenter trial of captopril therapy in patients with type 1 diabetes with…

Tags: 1999, Adult, American journal of kidney diseases : the official journal of the National Kidney Foundation, Angiotensin-Converting Enzyme Inhibitors/*therapeutic use, Antihypertensive Agents/*therapeutic use, Bain R P, Blood Pressure/drug effects, Blumenthal S, Captopril/*therapeutic use, Cattran D, Chronic/etiology, Creatinine/blood, Department of Internal Medicine, Diabetes Mellitus, Diabetic Nephropathies/*drug therapy/physiopathology, Disease Progression, Female, Follow-Up Studies, Hebert L A, Humans, Kidney Failure, Levey A S, Lewis E J, Lewis J B, Male, Middle Aged, NEOMED College of Medicine, Nephrotic Syndrome/complications/*drug therapy/physiopathology, Prospective Studies, Proteinuria, Randomized Controlled Trials as Topic, Remission Induction, Rohde R D, Spitalewitz S, Type 1/*complications, Whittier F, Wilmer W A

Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice.

BACKGROUND: Heart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia. This study…

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