1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
427–430
Issue
3
Volume
15
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Simultaneous presentation of facial nerve neuroma and otosclerosis.
Publisher
An entity responsible for making the resource available
The American journal of otology
Date
A point or period of time associated with an event in the lifecycle of the resource
1994
1994-05
Subject
The topic of the resource
Adult; Humans; Male; Magnetic Resonance Imaging; Functional Laterality; Evoked Potentials; Audiometry; Cranial Nerve Neoplasms/diagnosis/*pathology/surgery; Deafness/diagnosis/etiology; Facial Nerve/*pathology/surgery; Neuroma/diagnosis/*pathology/surgery; Otosclerosis/*complications/diagnosis/*physiopathology; Tinnitus/etiology; Auditory; Brain Stem
Creator
An entity primarily responsible for making the resource
Rizer F M; Guthikonda M; Lippy W H; Schuring A G
Description
An account of the resource
Otosclerosis often occurs as a unilateral mixed or conductive hearing loss. In the absence of retrocochlear findings, otologists usually do not pursue further diagnostic testing. A patient who presented to the Warren Otologic Group with a unilateral mixed hearing loss is discussed. He was followed for 1 year with the intent of scheduling a stapedectomy. Two weeks prior to the surgical date, the patient developed a sudden hearing loss and was admitted to the hospital for treatment. Magnetic resonance imaging demonstrated a tiny, enhancing mass in the lateral internal auditory canal, measuring 7 mm in diameter. At surgery, the tumor was found to originate at the union of the nervus intermedius and the facial nerve. The simultaneous occurrence of facial nerve neuroma and otosclerosis is discussed, with emphasis on a thorough evaluation of all unilateral mixed hearing losses, including those attributable to otosclerosis.
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1994
Adult
Audiometry
Auditory
Brain Stem
Cranial Nerve Neoplasms/diagnosis/*pathology/surgery
Deafness/diagnosis/etiology
Evoked Potentials
Facial Nerve/*pathology/surgery
Functional Laterality
Guthikonda M
Humans
Lippy W H
Magnetic Resonance Imaging
Male
Neuroma/diagnosis/*pathology/surgery
Otosclerosis/*complications/diagnosis/*physiopathology
Rizer F M
Schuring A G
The American journal of otology
Tinnitus/etiology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0378-5955(02)00376-3" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0378-5955(02)00376-3</a>
Pages
131–138
Issue
1
Volume
168
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Excitatory and facilitatory frequency response areas in the inferior colliculus of the mustached bat.
Publisher
An entity responsible for making the resource available
Hearing research
Date
A point or period of time associated with an event in the lifecycle of the resource
2002
2002-06
Subject
The topic of the resource
Acoustic Stimulation; Animal; Animals; Auditory; Auditory Perception/*physiology; Brain Stem; Chiroptera/*physiology; Echolocation; Evoked Potentials; Inferior Colliculi/*physiology; Neurons/physiology; Vocalization
Creator
An entity primarily responsible for making the resource
Portfors Christine V; Wenstrup Jeffrey J
Description
An account of the resource
In the mustached bat's central nucleus of the inferior colliculus (ICC), many neurons display facilitatory or inhibitory responses when presented with two tones of distinctly different frequencies. Our previous studies have focused on spectral interactions between specific frequency bands contained in the bat's sonar vocalization. In this study, we describe excitatory and facilitatory frequency response areas across all frequencies in the mustached bat's audible range. We show that many neurons in the ICC have more extensive frequency interactions than previously documented. We recorded responses of 96 single units to single tones and combinations of two tones. Best frequencies of the units ranged from 59-15 kHz. Forty-one units had a single, excitatory frequency response area. The rest of the units had more complex frequency tuning that included multiple excitatory frequency response areas and facilitatory frequency response areas. Some of the facilitatory frequency interactions were between one sound with energy in a sonar frequency band and a second sound with energy in a non-sonar frequency band. We also found that neurons could be facilitated by more than one additional frequency band. Our findings of extensive frequency interactions in the ICC of the mustached bat suggest that some neurons may be well suited for the analysis of complex sounds, possibly including social communication sounds.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0378-5955(02)00376-3" target="_blank" rel="noreferrer noopener">10.1016/s0378-5955(02)00376-3</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2002
Acoustic Stimulation
Animal
Animals
Auditory
Auditory Perception/*physiology
Brain Stem
Chiroptera/*physiology
College of Anatomy & Neurobiology
Department of Anatomy & Neurobiology
Echolocation
Evoked Potentials
Hearing research
Inferior Colliculi/*physiology
NEOMED College of Medicine
Neurons/physiology
Portfors Christine V
Vocalization
Wenstrup Jeffrey J
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/s0378-5955(01)00326-4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/s0378-5955(01)00326-4</a>
Pages
117–124
Issue
1
Volume
159
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Auditory nerve fiber differences in the normal and neurofilament deficient Japanese quail.
Publisher
An entity responsible for making the resource available
Hearing research
Date
A point or period of time associated with an event in the lifecycle of the resource
2001
2001-09
Subject
The topic of the resource
*Mutation; Animals; Auditory; Axons/ultrastructure; Brain Stem; Cochlear Nerve/*pathology/*physiopathology; Coturnix/genetics; Electron; Evoked Potentials; Microscopy; Myelin Sheath/ultrastructure; Nerve Fibers/pathology/physiology; Neurofilament Proteins/*deficiency/*genetics
Creator
An entity primarily responsible for making the resource
Sheykholeslami K; Kaga K; Mizutani M
Description
An account of the resource
A primary axonal disease affecting the central and peripheral nervous system was discovered in a mutant strain of the Japanese quail, named quiver (Quv). We have previously demonstrated altered auditory evoked potentials in the neurofilament (NF) deficient quail. In this current study we attempt to find relationships between the auditory evoked potential results and the histo-pathological abnormalities of the auditory neurons. No abnormalities in the external auditory meatus and tympanic cavity were observed in either Quv or control quails and the ganglion cell bodies and their nuclei appeared normal by light microscopy. The myelin staining pattern was found to be similar in both strains with hematoxylin and eosin and Kluver-Barrera staining. The frequency histograms of fiber and axonal diameters of myelinated fibers showed an unimodal pattern in both strains. In Quv quails myelinated fibers and their axoplasm were smaller in diameter than in controls resulting in smaller neural tissue mass. In electron microscopic observation the axons of the Quv quail were composed of mitochondria and microtubules and smooth endoplasmic reticuli. In Quv quail electron micrographs of cochlear nerve myelinated fibers NFs were not seen in the axons and the neuronal cell bodies. Our current findings indicate that the previously reported reduction of conduction velocity of auditory evoked potentials may be due to smaller fiber and/or axonal diameter. The g-ratio, myelin thickness and fiber circularity were found to be the same for both strains. In conclusion, loss of axonal cytoskeletal elements (NFs) correlates well with our electrophysiological findings. Reduced conduction velocity and severely distorted auditory evoked potentials in NF deficient quails seem to be primarily due to axonal hypotrophy.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/s0378-5955(01)00326-4" target="_blank" rel="noreferrer noopener">10.1016/s0378-5955(01)00326-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
*Mutation
2001
Animals
Auditory
Axons/ultrastructure
Brain Stem
Cochlear Nerve/*pathology/*physiopathology
Coturnix/genetics
Electron
Evoked Potentials
Hearing research
Kaga K
Microscopy
Mizutani M
Myelin Sheath/ultrastructure
Nerve Fibers/pathology/physiology
Neurofilament Proteins/*deficiency/*genetics
Sheykholeslami K
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s10162-011-0276-1" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s10162-011-0276-1</a>
Pages
647–658
Issue
5
Volume
12
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Development of tinnitus in CBA/CaJ mice following sound exposure.
Publisher
An entity responsible for making the resource available
Journal of the Association for Research in Otolaryngology : JARO
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
2011-10
Subject
The topic of the resource
Animals; Auditory; Brain Stem; Evoked Potentials; Inbred CBA; Mice; Noise/*adverse effects; Reflex; Startle; Tinnitus/*etiology/physiopathology
Creator
An entity primarily responsible for making the resource
Longenecker Ryan J; Galazyuk Alexander V
Description
An account of the resource
Tinnitus, the perception of a sound without an external acoustic source, is a complex perceptual phenomenon affecting the quality of life in 17% of the adult population. Despite its ubiquity and morbidity, the pathophysiology of tinnitus is a work in progress, and there is no generally accepted cure or treatment. Development of a reliable common animal model is crucial for tinnitus research and may advance this field. The goal of this study was to develop a tinnitus mouse model. Tinnitus was induced in an experimental group of mice by an exposure to a loud (116 dB sound pressure level (SPL)) narrow band noise (one octave, centered at 16 kHz) during 1 h under anesthesia. The tinnitus was then assessed behaviorally by measuring gap induced suppression of the acoustic startle reflex. We found that a vast majority of the sound-exposed mice (86%) developed behavioral signs of tinnitus. This was a complex, long lasting, and dynamic process. On the day following exposure, all mice demonstrated signs of acute tinnitus over the entire range of sound frequencies used for testing (10-31 kHz). However, 2-3 months later, a behavioral evidence of tinnitus was evident only at a narrow frequency range (20-31 kHz) representing a presumed chronic condition. Extracellular recordings confirmed a significantly higher rate of spontaneous activity in inferior colliculus neurons in sound-exposed compared to control mice. Surprisingly, unilateral sound exposure suppresses startle responses in mice and they remained suppressed even 3 months post-exposure, whereas auditory brainstem response thresholds were completely recovered during 2 months following exposure. In summary, behavioral evidence of tinnitus can be reliably developed in mice by sound exposure, and tinnitus induction can be assessed by quantifying prepulse inhibition of the acoustic startle reflex.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s10162-011-0276-1" target="_blank" rel="noreferrer noopener">10.1007/s10162-011-0276-1</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
Animals
Auditory
Brain Stem
Department of Anatomy & Neurobiology
Evoked Potentials
Galazyuk Alexander V
Inbred CBA
Journal of the Association for Research in Otolaryngology : JARO
Longenecker Ryan J
Mice
NEOMED College of Medicine
Noise/*adverse effects
Reflex
Startle
Tinnitus/*etiology/physiopathology