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Safety and efficacy of cangrelor, an intravenous, short-acting platelet inhibitor in patients requiring coronary artery bypass surgery.

OBJECTIVE: Oral P2Y(1)(2) platelet receptor inhibitors are a cornerstone of reducing complications in patients with acute coronary syndromes or coronary stents. Guidelines advocate discontinuing treatment with P2Y(1)(2) platelet receptor inhibitors…

Tags: 2013, 80 and over, Adenosine Monophosphate/administration & dosage/*analogs & derivatives, Administration, Adult, Aged, Angiolillo Dominick J, Blood Transfusion/*statistics & numerical data, Brtko Miroslav, Cannon Louis A, Chandna Harish, Chronos Nicholas, Combination/statistics & numerical data, Coronary Artery Bypass/*statistics & numerical data, Dietrich Markus, Drug Therapy, Drug-Related Side Effects and Adverse Reactions/epidemiology, Dyke Cornelius M, Female, Firstenberg Michael S, Holmes David R, Humans, Hutyra Martin, Injections, Intravenous, Liu Tiepu, Male, Manoukian Steven V, Middle Aged, Montalescot Gilles, Oral, Placebo Effect, Platelet Aggregation Inhibitors/administration & dosage, Postoperative Hemorrhage/*epidemiology/*prevention & control, Prats Jayne, Premedication/*statistics & numerical data, Prevalence, Price Matthew, Purinergic P2Y Receptor Antagonists/administration & dosage, Pyridines/*administration & dosage, Ramaiahm Chandrashekar, Risk Assessment, The heart surgery forum, Todd Meredith, Topo Eric J, Treatment Outcome, Tummala Pradyumna, United States/epidemiology, Voeltz Michele, Welsby Ian

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