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Text
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<a href="http://doi.org/10.1016/j.jemermed.2015.08.008" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/j.jemermed.2015.08.008</a>
Pages
e183–186
Issue
6
Volume
49
Dublin Core
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Title
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Type 1 Brugada Pattern Associated with Nicotine Toxicity.
Publisher
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The Journal of emergency medicine
Date
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2015
2015-12
Subject
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Adult; Adverse Drug Event; Behavior Rating Scales; Brugada pattern; Brugada syndrome; Brugada Syndrome – Chemically Induced; Brugada Syndrome – Diagnosis; Brugada Syndrome – Therapy; Brugada Syndrome/*chemically induced/*diagnosis/therapy; cardiac sodium channels; Drug-Related Side Effects and Adverse Reactions; electrocardiogram; Electrocardiography; Female; Humans; implanted cardioverter defibrillator; Nicotine; nicotine toxicity; Nicotine/*toxicity; sudden cardiac death; Tobacco Use Cessation Devices/*adverse effects; Tobacco Use Cessation Products – Adverse Effects
Creator
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Ondrejka Jason; Giorgio Gary
Description
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BACKGROUND: Brugada pattern (BrP) findings on electrocardiogram (ECG) are mandatory for the diagnosis of Brugada syndrome (BrS). BrS is an incompletely understood cause of sudden cardiac death. CASE REPORT: Our patient was a young woman who was using topical nicotine for assistance in smoking cessation at a relatively high dose compared to her daily cigarette intake. She presented with symptoms of mild nicotine toxicity and had an ECG with a type 1 BrP. An ECG the next day was normal and electrophysiology consultation was conducted. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Recognition of a BrP ECG by emergency physicians is critical because this is the first step in diagnosing BrS, a condition that is characterized by ventricular dysrhythmias and sudden cardiac death. In addition, ECG abnormalities can be transient in nature, requiring vigilance by the emergency physician to prevent the patients' potential life threat from going undiagnosed. We present the first case to our knowledge of a BrP associated with nicotine toxicity. We also discuss treatment and disposition recommendations.
Identifier
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<a href="http://doi.org/10.1016/j.jemermed.2015.08.008" target="_blank" rel="noreferrer noopener">10.1016/j.jemermed.2015.08.008</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2015
Adult
adverse drug event
Behavior Rating Scales
Brugada pattern
Brugada syndrome
Brugada Syndrome – Chemically Induced
Brugada Syndrome – Diagnosis
Brugada Syndrome – Therapy
Brugada Syndrome/*chemically induced/*diagnosis/therapy
cardiac sodium channels
Department of Emergency Medicine
Drug-Related Side Effects and Adverse Reactions
electrocardiogram
Electrocardiography
Female
Giorgio Gary
Humans
implanted cardioverter defibrillator
NEOMED College of Medicine
Nicotine
nicotine toxicity
Nicotine/*toxicity
Ondrejka Jason
sudden cardiac death
The Journal of emergency medicine
Tobacco Use Cessation Devices/*adverse effects
Tobacco Use Cessation Products – Adverse Effects