Browse Items · NEOMED Bibliography Database

Cell cycle arrest and autoschizis in a human bladder carcinoma cell line following Vitamin C and Vitamin K3 treatment.

Exponentially growing cultures of human bladder tumor cells (T24) were treated with Vitamin C (VC) alone, Vitamin K(3) (VK(3)) alone, or with a VC:VK(3) combination for 1, 2, or 4hr. Flow cytometry of T24 cells exposed to the vitamins for 1h revealed…

G protein coupling profile of mGluR6 and expression of G alpha proteins in retinal ON bipolar cells.

Metabotropic glutamate receptor 6 (mGluR6) is a group III, pertussis toxin (PTX)-sensitive G protein coupled mGluR that plays a specialized role in the retina. Retinal ON bipolar cells, which receive direct glutamatergic input from photoreceptor…

Neurokinin-1 receptor resensitization precedes receptor recycling.

Following agonist binding, neurokinin-1 receptors undergo rapid desensitization followed by internalization and recycling. Desensitization requires receptor phosphorylation but does not require internalization, whereas resensitization is thought to…

Tags: 2005, Adenosine Triphosphate/pharmacology, Animals, Bennett V J, Binding, Calcium/metabolism, CHO Cells, Competitive, Cricetinae, Guanylyl Imidodiphosphate/pharmacology, Neurokinin-1/*metabolism, Perrine S A, Phosphorylation, Rats, Receptors, Simmons M A, Substance P/metabolism, The Journal of pharmacology and experimental therapeutics

Specificity of metabotropic glutamate receptor 2 coupling to G proteins.

Metabotropic glutamate receptor 2 (mGluR2) is a class 3 G protein-coupled receptor and an important mediator of synaptic activity in the central nervous system. Previous work demonstrated that mGluR2 couples to pertussis toxin (PTX)-sensitive G…

Postinhibitory rebound neurons and networks are disrupted in retrovirus-induced spongiform neurodegeneration.

Certain retroviruses induce progressive spongiform motor neuron disease with features resembling prion diseases and amyotrophic lateral sclerosis. With the neurovirulent murine leukemia virus (MLV) FrCasE, Env protein expression within glia leads to…

Tags: 2014, Action Potentials/physiology, Animals, Antigens/metabolism, auditory midbrain, Calcium/metabolism, Davey Robert A, Department of Integrative Medical Sciences, env/metabolism, Experimental/physiopathology, Gene Products, Hearing Loss/physiopathology, Inferior Colliculi/physiopathology/virology, inferior colliculus, Journal of neurophysiology, Leukemia, Leukemia Virus, Li Ying, Lynch William P, Membrane Potentials/physiology, Mice, Microglia/physiology/virology, Murine/*physiology, NEOMED College of Medicine, Neural Pathways/physiopathology, Neurodegenerative Diseases/*physiopathology, Neuroglia/physiology/virology, Neurons/*physiology/virology, Patch-Clamp Techniques, postinhibitory rebound neurons, Proteoglycans/metabolism, Retroviridae Infections/*physiopathology/virology, retrovirus, Sivaramakrishnan Shobhana, Tissue Culture Techniques, Tumor Virus Infections/*physiopathology/virology, Voltage-Sensitive Dye Imaging, voltage-sensitive dyes

L-type calcium channels refine the neural population code of sound level.

The coding of sound level by ensembles of neurons improves the accuracy with which listeners identify how loud a sound is. In the auditory system, the rate at which neurons fire in response to changes in sound level is shaped by local networks.…

Mineral deposition in the extracellular matrices of vertebrate tissues: identification of possible apatite nucleation sites on type I collagen.

The possible means by which type I collagen may mediate mineralization in normal vertebrate bone, tendon, dentin and cementum as well as in pathological mineral formation are not fully understood. One consideration in this regard is that the…

Tags: *Calcification, 2009, Animals, Apatites/*metabolism, Calcium/metabolism, Cells, tissues, organs, Collagen Type I/chemistry/*metabolism, Extracellular Matrix/*metabolism, Humans, Landis William J, Microfibrils/chemistry, Models, Molecular, Phosphates/metabolism, Physiologic, Silver Frederick H, Vertebrates/*metabolism

Browse Items (7 total)