1
40
4
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
351–355
Issue
2
Volume
30
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Discriminative stimulus control by the anxiogenic beta-carboline FG 7142: generalization to a physiological stressor.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1988
1988-06
Subject
The topic of the resource
Male; Animals; Rats; Discrimination Learning/*drug effects; Avoidance Learning/drug effects; Appetite Depressants/*pharmacology; Carbolines/*pharmacology; Stress; Inbred Strains; Generalization; Stimulus/*drug effects; Physiological/*psychology
Creator
An entity primarily responsible for making the resource
Leidenheimer N J; Schechter M D
Description
An account of the resource
Drug discrimination was employed to investigate the similarities between FG
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1988
Animals
Appetite Depressants/*pharmacology
Avoidance Learning/drug effects
Carbolines/*pharmacology
Discrimination Learning/*drug effects
Generalization
Inbred Strains
Leidenheimer N J
Male
Pharmacology, biochemistry, and behavior
Physiological/*psychology
Rats
Schechter M D
Stimulus/*drug effects
Stress
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0091-3057(92)90641-r" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0091-3057(92)90641-r</a>
Pages
77–83
Issue
1
Volume
43
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Evidence for noradrenergic involvement in mediating the FG 7142 discriminative stimulus.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1992
1992-09
Subject
The topic of the resource
Adrenergic alpha-Antagonists/pharmacology; Animals; Appetite Depressants/*pharmacology; Carbolines/*pharmacology; Clonidine/pharmacology; Dioxanes/pharmacology; Discrimination (Psychology)/*drug effects; Electroshock; Generalization; Idazoxan; Male; Norepinephrine/*physiology; Psychological/psychology; Rats; Sprague-Dawley; Stimulus/drug effects; Stress; Yohimbine/pharmacology
Creator
An entity primarily responsible for making the resource
Leidenheimer N J; Schechter M D
Description
An account of the resource
Rats were trained to discriminate the stimulus properties of the benzodiazepine receptor partial inverse agonist beta-carboline-3-carboxylate acid methyl amide (FG 7142) (5.0 mg/kg) or the alpha 2-adrenergic receptor antagonist 17 alpha-hydroxyyohimban-16 alpha-carboxylic acid methyl ester (yohimbine) (3.0 mg/kg) from vehicle in a two-lever, food-motivated operant task. These compounds have in common a beta-carboline structure and anxiogenic behavioral profiles. The yohimbine discriminative stimulus was mimicked by the alpha 2-adrenergic receptor antagonist idazoxan and antagonized by the alpha 2-adrenergic receptor agonist clonidine, indicating that the yohimbine stimulus was mediated through the alpha
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0091-3057(92)90641-r" target="_blank" rel="noreferrer noopener">10.1016/0091-3057(92)90641-r</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1992
Adrenergic alpha-Antagonists/pharmacology
Animals
Appetite Depressants/*pharmacology
Carbolines/*pharmacology
Clonidine/pharmacology
Dioxanes/pharmacology
Discrimination (Psychology)/*drug effects
Electroshock
Generalization
Idazoxan
Leidenheimer N J
Male
Norepinephrine/*physiology
Pharmacology, biochemistry, and behavior
Psychological/psychology
Rats
Schechter M D
Sprague-Dawley
Stimulus/drug effects
Stress
Yohimbine/pharmacology
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1016/0741-8329(88)90075-4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1016/0741-8329(88)90075-4</a>
Pages
331–335
Issue
4
Volume
5
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Interaction of ethanol and tetrahydro-beta-carboline (THBC) in a discriminative task.
Publisher
An entity responsible for making the resource available
Alcohol (Fayetteville, N.Y.)
Date
A point or period of time associated with an event in the lifecycle of the resource
1988
1988-08
Subject
The topic of the resource
Male; Animals; Rats; Ethanol/*pharmacology; Behavior; Drug Interactions; Discrimination Learning/*drug effects; Conditioning (Psychology)/drug effects; Carbolines/*pharmacology; Dose-Response Relationship; Drug; Inbred Strains; Animal/drug effects
Creator
An entity primarily responsible for making the resource
Schechter M D; Signs S A
Description
An account of the resource
Rats (n = 10) were trained to discriminate between ethanol (600 mg/kg, IP) and its vehicle, or between THBC (20 mg/kg) and its vehicle in a two-lever food-motivated operant task. Once the discriminative training criterion was attained, rats in each group were administered different doses of both ethanol and THBC. The ED50 of ethanol in the ethanol-trained rats was 298.0 mg/kg and 15 mg/kg THBC produced ethanol-like responding. The ED50 of THBC in the THBC-trained rats was 3.63 mg/kg and 1200 mg/kg ethanol produced THBC-like responding. The cross-generalization between ethanol and THBC is, thus, indicated and relates to previous evidence in which both ethanol- and THBC-trained rats generalize to a common agent, TFMPP, a putatively specific 5HT1B receptor agonist. Taken together, these observations suggest that beta-carbolines may play a role in the discriminative stimulus properties of ethanol.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1016/0741-8329(88)90075-4" target="_blank" rel="noreferrer noopener">10.1016/0741-8329(88)90075-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1988
Alcohol (Fayetteville, N.Y.)
Animal/drug effects
Animals
Behavior
Carbolines/*pharmacology
Conditioning (Psychology)/drug effects
Discrimination Learning/*drug effects
Dose-Response Relationship
Drug
Drug Interactions
Ethanol/*pharmacology
Inbred Strains
Male
Rats
Schechter M D
Signs S A
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Pages
1–6
Issue
1
Volume
28
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Tetrahydro-beta-carboline may produce its stimulus effects via 5HT1B receptors.
Publisher
An entity responsible for making the resource available
Pharmacology, biochemistry, and behavior
Date
A point or period of time associated with an event in the lifecycle of the resource
1987
1987-09
Subject
The topic of the resource
Male; Animals; Rats; Serotonin/*metabolism; Piperazines/pharmacology; Discrimination Learning/drug effects; Serotonin Antagonists/pharmacology; Carbolines/*pharmacology; Metergoline/pharmacology; Inbred Strains; Receptors
Creator
An entity primarily responsible for making the resource
Schechter M D
Description
An account of the resource
To further clarify the role of 5-hydroxytryptamine (5HT) in the behavioral effects of tetrahydro-beta-carboline, male rats were trained to discriminate either 20 mg/kg THBC from its vehicle (n = 10) or 2.0 mg/kg fenfluramine from saline (n = 5). THBC was observed to produce fenfluramine-like effects in the fenfluramine-trained rats while fenfluramine produced THBC-like effects in the
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
1987
Animals
Carbolines/*pharmacology
Discrimination Learning/drug effects
Inbred Strains
Male
Metergoline/pharmacology
Pharmacology, biochemistry, and behavior
Piperazines/pharmacology
Rats
Receptors
Schechter M D
Serotonin Antagonists/pharmacology
Serotonin/*metabolism