Browse Items · NEOMED Bibliography Database

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.

Tumor vessels are characterized by abnormal morphology and hyperpermeability that together cause inefficient delivery of chemotherapeutic agents. Although vascular endothelial growth factor has been established as a critical regulator of tumor…

NUT Midline Carcinoma: A Rare Malignancy.

Nuclear protein of the testis (NUT) midline carcinoma can present in the head, neck, and mediastinum. In general, it presents in young adult men and has a poor prognosis. We report on a case of NUT midline carcinoma of the mediastinum in a man 27…

Tags: 2017, Adult, Al Aukla Nidal, Al Diffalha Sameer, Cancer Control: Journal of the Moffitt Cancer Center, Carcinoma, Carcinoma – Diagnosis, Carcinoma – Metabolism, Dickinson Shohreh, Hasan Saleh, Khalil Farah, Male, Mediastinal Neoplasms – Diagnosis, Mediastinal Neoplasms – Metabolism, Nuclear Proteins – Metabolism, Proteins – Metabolism, Squamous Cell – Diagnosis, Squamous Cell – Metabolism

Guidelines of care for the management of cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human cancer and has an increasing annual incidence. Although most cSCC is cured with office-based therapy, advanced cSCC poses a significant risk for morbidity, impact on…

Tags: 2018, 5-year follow-up, Alam M, american joint committee, Armstrong A, Baum C, Begolka W S, Bichakjian C, Biopsy, Bordeaux J S, Boyer K, Brown M, Busam K J, Carcinoma, curettage, Department of Family & Community Medicine, Dermatology, Eisen D B, fresh tissue technique, Huang C, Iyengar V, Journal Article or Conference Abstract Publication, Journal of the American Academy of Dermatology, Kim J Y S, Kozlow J H, limited life expectancy, Lober C, lymph-node biopsy, Margolis D J, Messina J, Metastasis, Miller A, Miller S, Mittal B, mohs micrographic surgery, Mostow E, Mowad C, Moyer J, Nehal K, NEOMED College of Medicine, nonmelanoma skin-cancer, Olenecki T, organ transplant, Phototherapy, Radiotherapy, randomized controlled-trial, recipients, Rodgers P, Schmitt-Burr K, Sekulic A, squamous cell, Staging, Storrs P, Surgery, surveillance, Teng J, topical photodynamic therapy, topical therapy, Yu S

Osteoactivin regulates head and neck squamous cell carcinoma invasion by modulating matrix metalloproteases.

Nearly 60% of patients with head and neck squamous cell carcinoma (HNSCC) die of metastases or locoregional recurrence. Metastasis is mediated by cancer cell migration and invasion, which are in part dependent on extracellular matrix degradation by…

Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas.

Nearly 50% of patients with oral squamous cell carcinoma (OSCC) die of metastases or locoregional recurrence. Metastasis is mediated by cancer cell adhesion, migration, and invasion. Osteoactivin (OA) overexpression plays a role in metastases in…

Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway.

Dietary Phytochemicals In The Chemoprevention And Treatment Of Hepatocellular Carcinoma: In Vivo Evidence, Molecular Targets, And Clinical Relevance

Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, the majority of detected cases of liver cancer have been found in the developing nations of Asia and Africa; however,…

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.

Hepatocellular carcinoma (HCC), one of the most prevalent and lethal cancers, has shown an alarming rise in the USA. Without effective therapy for HCC, novel chemopreventive strategies may effectively circumvent the current morbidity and mortality.…

Angiogenesis in hepatocellular carcinoma: a potential target for chemoprevention and therapy.

Hepatocellular carcinoma (HCC) remains one of the most lethal cancers in the world. Since current treatment options including surgical resection and liver transplantation offer limited therapeutic benefits, there exists a need to evaluate novel…

Tags: 2012, Angiogenesis Inhibitors/*therapeutic use, Animals, Bishayee Anupam, Carcinoma, Current cancer drug targets, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/blood supply/pathology/*prevention & control, Humans, Liver Neoplasms/blood supply/pathology/*prevention & control, NEOMED College of Pharmacy, Neovascularization, Pathologic/*prevention & control

Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cells.

Dietary antioxidants, such as anthocyanins, are helpful in the prevention and control of various diseases by counteracting the imbalance of oxidative and antioxidative factors in the living systems. Black currant (Ribes nigrum L., Grossulariaceae) is…

Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is one of the most common cancers and lethal diseases in the world. Although the majority of HCC cases occur in developing countries of Asia and Africa, the prevalence of liver cancer has risen considerably in Japan,…

Complete remission in a patient with metastatic mixed adenocarcinoma/extrapulmonary small cell carcinoma of the prostate.

Approximately 10% of all extra-pulmonary small cell carcinoma (EPSCC) arises in the prostate either as de novo mixed adenocarcinoma with small cell components or a pure small cell carcinoma. Extensive disease carries a median survival of about 10…

Tags: 2011, Adenocarcinoma/diagnosis/*secondary, Androgen Antagonists/therapeutic use, Bone Neoplasms/*drug therapy/*secondary, Brammer Jonathan Edward, Carcinoma, Cisplatin/therapeutic use, Combined Modality Therapy, Etoposide/therapeutic use, Humans, International journal of clinical oncology, Lulla Premal, Lung Neoplasms/diagnosis/*secondary, Lynch Garrett Rush, Male, Middle Aged, Prostatic Neoplasms/*drug therapy/metabolism/*pathology, Remission Induction, Small Cell/diagnosis/*secondary

The persistent nonhealing ulcer. Could it be basal cell carcinoma?

Tags: 2001, Aged, Basal Cell – Diagnosis, Basal Cell – Physiopathology, Basal Cell/complications/*pathology, Brodell R T, Carcinoma, Chronic Disease, Diagnosis, Differential, Humans, Male, Postgraduate medicine, Risk Factors, Skin Neoplasms/complications/*pathology, Ulcer/*etiology, Wagamon K

Lack of Association Between Dexamethasone and Long-Term Survival After Non-Small Cell Lung Cancer Surgery.

OBJECTIVE: To evaluate the association between the use of intraoperative dexamethasone with an increase in recurrence-free survival (RFS) and overall survival (OS) after non-small cell lung cancer (NSCLC) surgery. DESIGN: This was a propensity…

Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis.

UNLABELLED: Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. TGR5 activation also inhibits nuclear factor kappaB (NF-kappaB)-mediated inflammation. Here we…

Humoral hypercalcemia of malignancy in squamous cell carcinoma of the skin: parathyroid hormone–related protein as a cause.

The second most common cause of hypercalcemia is humoral hypercalcemia of malignancy (HHM), a condition associated with increased mortality. Although hypercalcemia is usually seen in squamous cell cancers, only 13 cases have been described in…

Signet Ring Cell Carcinoma of the Ampulla of Vater with Early Development of Bone Metastasis: Case Report and Review of the Rare Malignancy.

Tags: 2016, Ampulla of Vater/*pathology/surgery, Bone Neoplasms/*secondary/surgery, Carcinoma, Cocieru Andrei, Common Bile Duct Neoplasms/*pathology/surgery, Damania Rahul, Humans, Journal of gastrointestinal cancer, Male, Middle Aged, Prognosis, Signet Ring Cell/*pathology/surgery, Weaver Joshua

Curcumin and liver cancer: a review.

Primary liver cancer, also known as hepatocellular carcinoma (HCC), is one of the most lethal cancers having worldwide prevalence. Although most HCC cases are reported in the developing countries of Asia and Africa, there has been an alarming…

Tags: 2012, Aggarwal Bharat B, Animals, Anti-Inflammatory Agents/therapeutic use, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carcinoma, Curcumin/*therapeutic use, Current pharmaceutical biotechnology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/*drug therapy/prevention & control, Humans, Liver Neoplasms/*drug therapy/prevention & control, NEOMED College of Pharmacy, Phytogenic/*therapeutic use

Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.

The prophylactic and therapeutic properties of tea have been attributed to green tea catechins and black tea theaflavins besides several other polyphenolic compounds. Tea polyphenols possess potent antioxidant and antiinflammatory properties and…

Selenium in the prevention and treatment of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) happens to be one of the most lethal cancers in the world. Even though most cases occur in the developing world, reported cases in Western Europe as well as North America are on a steep rise. Human HCC etiology includes…

Tags: 2010, Animal, Animals, Anti-cancer agents in medicinal chemistry, Anticarcinogenic Agents/*therapeutic use, Bishayee Anupam, Carcinoma, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/chemically induced/*drug therapy/etiology/*prevention & control, Humans, Liver Neoplasms/chemically induced/*drug therapy/etiology/*prevention & control, Models, NEOMED College of Pharmacy, Oxidative Stress, Selenium/*therapeutic use

Metastatic renal cell carcinoma to the thyroid gland.

OBJECTIVE: To examine the presentation, diagnosis, and appropriate management of renal clear cell carcinoma metastasis to the thyroid gland. METHODS: We describe a clinical case of solitary thyroid metastasis from renal clear cell carcinoma and…

Tags: 2008, Carcinoma, Duggal Neal Murari, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Horattas Mark C, Humans, Kidney Neoplasms/*pathology, Male, Middle Aged, Renal Cell/*secondary, Thyroid Neoplasms/*secondary

Suppression Of The Invasive Capacity Of Human Breast Cancer Cells By Inhibition Of Urokinase Plasminogen Activator Via Amiloride And B428

Tags: 2000, American Surgeon, angiogenesis, Carcinoma, Evans D M, integrins, migration, Prevention, prognostic marker, proliferation, pulmonary metastases, Receptor, Sloan-Stakleff K, Surgery, tumor-cells

Barretts-esophagus - An Acquired Condition With Genetic Predisposition

Tags: 1993, Adenocarcinoma, American Journal of Gastroenterology, Carcinoma, columnar epithelium, Dysplasia, Fahmy N, Gastroenterology & Hepatology, King J F, spectrum

Basal cell adenocarcinoma of minor salivary glands.

Basal cell adenocarcinoma of minor salivary glands is a relatively rare slow-growing tumor with an infiltrating growth pattern. The infiltrating growth pattern and likelihood of vascular and perineural involvement distinguishes basal cell…

Tags: 2007, Adenocarcinoma/*diagnosis/radiotherapy/surgery, Adenoid Cystic/diagnosis, Adenoma/diagnosis, Archives of pathology & laboratory medicine, Carcinoma, Chang Yilan L, Combined Modality Therapy, Diagnosis, Differential, Farrell Tisha, Humans, Minor/*pathology/surgery, Salivary Gland Neoplasms/*diagnosis/radiotherapy/surgery, Salivary Glands, Squamous Cell/diagnosis

Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).

Cholesterol 7 alpha-hydroxylase catalyzes the first and rate-limiting step in the conversion of cholesterol to bile acids in the liver. Previously, we have identified two bile acid response elements located in nt -74 to -54 (BARE-I) and -148 to -118…

Differences in the integration pattern and episomal forms of human papillomavirus type 16 DNA found within an invasive cervical neoplasm and its metastasis.

Human papillomavirus (HPV) type 16 DNA was found in three separate neoplastic lesions within a female patient. The physical state of the viral DNA in each lesion was determined by two-dimensional agarose gel electrophoresis. The primary cervical…

Widespread Metastases After Resection Of Noninvasive Thymoma

Tags: 2008, Carcinoma, expression, Gamboa E O, Haller N A, Hazra S V, Journal of Clinical Oncology, Lanoy R S, oncology, organization histologic classification, Powell A T, relevance, Sawhney V, stage, thymic epithelial tumors

Lipid Deposits And Lipo-mucosomes In Human Cholecystitis And Epithelial Metaplasia In Chronic Cholecystitis

Pseudocirrhosis in Breast Cancer - Experience From an Academic Cancer Center.

Background: Pseudocirrhosis is characterized by radiological changes in the liver that resemble cirrhosis, but with more rapid onset and progression. Though reported most frequently in patients with metastatic breast cancer, little is known about its…

Antitumor effect of novel silatranes on renal cell carcinoma in mice.

The effect of several novel silatrane derivatives on the growth of syngeneic renal cell carcinoma (RENCA) in BALB/c mice and the survival rate of the animals were evaluated. The RENCA-bearing animals were treated subcutaneously and weekly with either…

Tags: *Bridged Bicyclo Compounds, *Organosilicon Compounds, 1992, Animals, Anticancer research, Antineoplastic Agents/pharmacology/*therapeutic use, Bridged Bicyclo Compounds/pharmacology/*therapeutic use, Carcinoma, Female, Grna A, Heterocyclic, Hogan J, Inbred BALB C, Kidney Neoplasms/*drug therapy, Koo P H, Mice, Renal Cell/*drug therapy, Silicon/pharmacology/*therapeutic use, Structure-Activity Relationship

Evaluation Of Appropriate Short-term Mammographic Surveillance In Patients Who Undergo Breast-conserving Surgery (bcs)

Mammography is an important surveillance tool for detecting ipsilateral breast tumor recurrence (IBTR) after BCS. Although IBTR is rare in the first 2 years, various organizations have established protocols for postoperative mammographic…

Tags: 2012, Annals of surgical oncology, Cancer, Carcinoma, conservative surgery, Follow-up, Gunia S R, irradiation, Journal Article or Conference Abstract Publication, local recurrence, Lumpectomy, Mamounas E P, Merrigan T L, oncology, Poulton T B, radiation-therapy, Radiotherapy, stage-i, Surgery

Disseminated brown tumors from hyperparathyroidism masquerading as metastatic cancer: a complication of parathyroid carcinoma.

Osteitis fibrosa cystica (brown tumors) can be a skeletal manifestation of advanced hyperparathyroidism, including parathyroid cancer. Severe osteitis fibrosa cystica can mimic metastatic bone diseases especially in patients with a history of cancer.…

Tags: 2001, Carcinoma, Carcinoma/*complications, Diagnosis, Differential, Female, Gupta A, Horattas M C, Humans, Hyperparathyroidism/complications, Kidney Neoplasms/pathology, Middle Aged, Moattari A R, Osteitis Fibrosa Cystica/*diagnosis/*etiology, Parathyroid Neoplasms/*complications, Renal Cell/secondary, Shorten S D, The American surgeon

Renal Cell Carcinoma Metastatic to the Gallbladder.

Tags: 2018, Aged, Carcinoma, Cholecystectomy, Cocieru Andrei, Deeken Amy, Female, Gallbladder Neoplasms/diagnostic imaging/pathology/*secondary/surgery, Gallbladder/diagnostic imaging/pathology/surgery, Hazen Ben, Humans, Journal of gastrointestinal cancer, Kidney Neoplasms/diagnostic imaging/*pathology, Renal Cell/diagnostic imaging/pathology/*secondary/surgery, Tomography, X-Ray Computed

Phase II study of gefitinib in patients with advanced salivary gland cancers.

BACKGROUND: The purpose of this study was to determine the antitumor activity of the epidermal growth factor receptor (EGFR) inhibitor gefitinib in patients with recurrent/metastatic salivary gland cancer. METHODS: We conducted a phase II study in…

Tags: 2015, 80 and over, Adenocarcinoma/drug therapy/mortality/pathology, adenoid cystic carcinoma, Adenoid Cystic/*drug therapy/mortality/pathology, Adult, Aged, Antineoplastic Agents/*therapeutic use, Blumenschein George R Jr, Carcinoma, Department of Internal Medicine, Disease-Free Survival, Dose-Response Relationship, Drug, Drug Administration Schedule, El-Naggar Adel K, Female, Gefitinib, Glisson Bonnie S, Gonzalez-Angulo Ana M, Head & neck, Humans, Jakob John A, Kies Merrill S, Kupferman Michael E, Lee J Jack, Liu Diane D, Local/*drug therapy/mortality/pathology, Male, Maximum Tolerated Dose, Middle Aged, NEOMED College of Medicine, Neoplasm Invasiveness/pathology, Neoplasm Recurrence, Neoplasm Staging, non-adenoid cystic carcinoma, Prognosis, Quinazolines/*therapeutic use, Remission Induction, response to therapy, salivary gland cancer, Salivary Gland Neoplasms/*drug therapy/mortality/pathology, Survival Analysis, Treatment Outcome

Ultrastructural nucleolar alterations induced by an ametantrone–poly r(A-U) complex.

The current study has documented changes in the ultrastructure as well as in the intranucleolar distribution of rDNA and rRNA in RT4 (human transitional cell bladder carcinoma) cell nucleoli following a 3-h exposure to toxic doses of 50 microM…

Immune mediated neurologic dysfunction as a paraneoplastic syndrome in renal cell carcinoma.

OBJECTIVE: To describe a case of cerebellar ataxia associated with renal cell carcinoma. CASE REPORT: A 53-year-old Caucasian male with a history of Schizophrenia presented with generalized weakness, nausea, vomiting, severe weight loss, and…

Tags: 2008, Antibodies/blood, Autoantibodies/analysis, Carcinoma, Department of Internal Medicine, Friedman Norman, Hagel Christian, Haller Nairmeen Awad, Hippocalcin/immunology/metabolism, Humans, Johnson Vijay, Journal of neuro-oncology, Kidney Neoplasms/*complications, Male, Middle Aged, NEOMED College of Medicine, Nervous System Diseases/etiology/*immunology/pathology, Paraneoplastic Syndromes/*complications/*etiology, Renal Cell/*complications

Bilateral adrenal metastases simulating abnormal renal uptake on a Ga-67 scan.

Tags: 2001, Adrenal Gland Neoplasms/pathology/*secondary, Carcinoma, Chalfant M L, Clinical nuclear medicine, Diagnosis, Differential, Female, Gallium Radioisotopes, Goyal M, Humans, Kidney/*diagnostic imaging, Konez O, Lung Neoplasms/*pathology, Middle Aged, Non-Small-Cell Lung/pathology/*secondary, Radionuclide Imaging, Radiopharmaceuticals

A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet.

Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-kappaB/HIF-1alpha pathway.

Due to the existence of cancer stem cells (CSCs), persistence and relapse of human hepatocellular carcinoma (HCC) are common after treatment with existing anti-cancer therapies. Emerging evidence indicates that lipopolysaccharide (LPS) plays a…

Tags: *Cancer stem cells, *Lipopolysaccharide, *Plasticity, *Stemness maintenance, *Tumor microenvironment, 2016, AC133 Antigen/genetics/*metabolism, alpha Subunit/genetics/*metabolism, Animals, Antineoplastic Agents – Pharmacodynamics, Antineoplastic Agents/pharmacology, Body Weights and Measures, Cancer letters, Carcinoma, Cell Line, Cell Movement – Drug Effects, Cell Movement/drug effects, Cell Physiology, Cell Physiology – Drug Effects, Cell Proliferation/drug effects, Department of Integrative Medical Sciences, Drug Resistance, Gene Expression Regulation, Genes, Genetic Techniques, Han Zhi-Peng, Hepatocellular, Hepatocellular – Drug Therapy, Hepatocellular – Metabolism, Hepatocellular – Pathology, Hepatocellular/drug therapy/genetics/*metabolism/pathology, Humans, Hypoxia-Inducible Factor 1, Inbred BALB C, Jing Ying-Ying, Lai Fo-Bao, Li Rong, Li Xiao-Yong, Lipopolysaccharides – Pharmacodynamics, Lipopolysaccharides/*pharmacology, Liu Jing-Feng, Liu Wen-Ting, Liver Neoplasms, Liver Neoplasms – Drug Therapy, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms/drug therapy/genetics/*metabolism/pathology, Male, Mice, NEOMED College of Medicine, Neoplasm, Neoplasm Invasiveness, Neoplastic, Neoplastic Stem Cells/*drug effects/metabolism/pathology, NF-kappa B – Metabolism, NF-kappa B/*metabolism, Nude, Pan Xiao-Rong, Phenotype, Proteins, Proteins – Metabolism, RNA Interference, Shi Rong-Yu, Signal Transduction – Drug Effects, Signal Transduction/drug effects, Stem Cells – Drug Effects, Stem Cells – Metabolism, Stem Cells – Pathology, Time Factors, Transfection, Tumor Burden, Tumor Microenvironment, Wei Li-Xin, Wu Meng-Chao, Yang Xue, Yu Guo-Feng, Zeng Jian-Xing, Zhang Hang-Jie, Zhang Ping, Zhao Qiu-Dong

Browse Items (79 total)