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Text
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URL Address
<a href="http://doi.org/10.1177/107327481702400214" target="_blank" rel="noreferrer noopener">http://doi.org/10.1177/107327481702400214</a>
Pages
202–206
Issue
2
Volume
24
Dublin Core
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Title
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NUT Midline Carcinoma: A Rare Malignancy.
Publisher
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Cancer Control: Journal of the Moffitt Cancer Center
Date
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2017
2017-04
Subject
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Adult; Male; Carcinoma; Proteins – Metabolism; Carcinoma – Diagnosis; Carcinoma – Metabolism; Mediastinal Neoplasms – Diagnosis; Mediastinal Neoplasms – Metabolism; Nuclear Proteins – Metabolism; Squamous Cell – Diagnosis; Squamous Cell – Metabolism
Creator
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Al Diffalha Sameer; Al Aukla Nidal; Hasan Saleh; Dickinson Shohreh; Khalil Farah
Description
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Nuclear protein of the testis (NUT) midline carcinoma can present in the head, neck, and mediastinum. In general, it presents in young adult men and has a poor prognosis. We report on a case of NUT midline carcinoma of the mediastinum in a man 27 years of age without any prior malignancy. Due to the location of the tumor, mediastinal lymphoma and germ cell tumor were initially considered; however, immunohistochemistry was performed using NUT antibody that revealed it to be NUT midline carcinoma. Although guidelines exist for squamous cell carcinoma of the head, neck, and mediastinum, no such specific guidelines are available for NUT midline carcinoma, which looks morphologically similar to squamous cell carcinoma but behaves more aggressively and carries a poor prognosis.
Identifier
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<a href="http://doi.org/10.1177/107327481702400214" target="_blank" rel="noreferrer noopener">10.1177/107327481702400214</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Adult
Al Aukla Nidal
Al Diffalha Sameer
Cancer Control: Journal of the Moffitt Cancer Center
Carcinoma
Carcinoma – Diagnosis
Carcinoma – Metabolism
Dickinson Shohreh
Hasan Saleh
Khalil Farah
Male
Mediastinal Neoplasms – Diagnosis
Mediastinal Neoplasms – Metabolism
Nuclear Proteins – Metabolism
Proteins – Metabolism
Squamous Cell – Diagnosis
Squamous Cell – Metabolism