MYOCARDITIS RESPONSE TO COLCHICINE THERAPY BASED ON CARDIAC MRI DIAGNOSTIC CRITERIA
An institutional CMR database was queried for all patients with pericarditis who had associated myocarditis. Those patients with at least 1 follow-up CMR study to assess response to therapy with a colchicine/NSAID regimen constituted the study population. Follow-up CMR studies were categorized as resolved, partially resolved, or no improvement with respect to myocarditis, based on consensus of 2 experienced CMR interpreters. At least 2 of the following were required to establish the diagnosis of myocarditis: abnormal T2-STIR images, elevated T1 relaxation time, elevated T2 relaxation time, or abnormal delayed enhancement imaging with gadolinium.
Because of anatomic proximity, myocarditis is often associated with pericarditis. Although randomized trials have not delineated a successful evidence-based therapy for myocarditis, there is evidence of considerable benefit in treating pericarditis with a regimen of colchicine and a non-steroidal anti-inflammatory drug (NSAID). Cardiac MRI (CMR) is capable of detecting both myocarditis and pericarditis. This study was designed to assess the effect of a colchicine/NSAID treatment regimen for myocarditis identified by CMR.
Behbahani-Nejad O; Mikolich B; Morgenstern D; Mikolich JR
Journal Of The American College Of Cardiology
2021
2021-05-03
Copyright © 2021 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Journal Article
<table width="91" style="border-collapse:collapse;width:68pt;"><colgroup><col width="91" style="width:68pt;" /></colgroup><tbody><tr style="height:15pt;"><td width="91" height="20" class="xl18" style="width:68pt;height:15pt;"><a href="http://doi.org/10.1016/S0735-1097(21)02790-X">http://doi.org/10.1016/S0735-1097(21)02790-X</a></td>
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Left Ventractilar Hypertrophy In Hypertensive Patients: A Reliable Diagnosis?
Cardiac MRI; Cardiovascular System & Cardiology; Echocardiography; Hypertension; Hypertrophy
Lisko J; Mikolich J R; Boniface N C; Hegde V; Tandon N; Mikolich B
Circulation
2013
2013-11
Journal Article or Conference Abstract Publication
n/a