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40
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Text
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URL Address
<a href="http://doi.org/10.14740/cr955" target="_blank" rel="noreferrer noopener">http://doi.org/10.14740/cr955</a>
Pages
76-88
Issue
2
Volume
11
ISSN
1923-2829 1923-2829
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Update Year & Number
June 2020 Update I
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Internal Medicine
Affiliated Hospital
Cleveland Clinic Akron General Hospital
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
An Update on the Pathophysiology and Treatment of Cardiorenal Syndrome.
Publisher
An entity responsible for making the resource available
Cardiology research
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
2020-04
Subject
The topic of the resource
cardiac resynchronization therapy; Cardiorenal syndrome; cardiovascular events; Chronic kidney disease; Chronic kidney disease; decompensated heart-failure; Heart failure; impact; left-ventricular dysfunction; preserved ejection fraction; risk; vasopressin; worsening renal-function
Creator
An entity primarily responsible for making the resource
Raina Rupesh; Nair Nikhil; Chakraborty Ronith; Nemer Lena; Dasgupta Rahul; Varian Kenneth
Description
An account of the resource
Cardiorenal syndrome (CRS) encompasses various disorders of the heart and kidneys; dysfunction of one organ leads to acute or chronic dysfunction of the other. It incorporates the intersection of heart-kidney interactions across several mediums, hemodynamically, through the alterations in neurohormonal markers, and increased venous and renal pressure, all of which are hallmarks of its clinical phenotypes. This article explores the epidemiology, pathology, classification and treatment of each type of CRS.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.14740/cr955" target="_blank" rel="noreferrer noopener">10.14740/cr955</a>
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
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journalArticle
2020
cardiac resynchronization therapy
Cardiology research
Cardiorenal syndrome
cardiovascular events
Chakraborty Ronith
Chronic kidney disease
Cleveland Clinic Akron General Hospital
Dasgupta Rahul
decompensated heart-failure
Department of Internal Medicine
Heart failure
impact
Journal Article
journalArticle
June 2020 Update I
left-ventricular dysfunction
Nair Nikhil
Nemer Lena
NEOMED College of Medicine
preserved ejection fraction
Raina Rupesh
Risk
Varian Kenneth
vasopressin
worsening renal-function
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.14740/cr690w" target="_blank" rel="noreferrer noopener">http://doi.org/10.14740/cr690w</a>
Pages
183–185
Issue
3
Volume
9
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Atrial Metastasis of Renal Cell Carcinoma: A Rare Presentation.
Publisher
An entity responsible for making the resource available
Cardiology research
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
2018-06
Subject
The topic of the resource
Inferior vena cava; Metastasis; Renal cell carcinoma; Right atrial mass
Creator
An entity primarily responsible for making the resource
Shah Shilpi; Vinod Poornima; Khayata Mohamed; Lane Jason L; Hegde Vinayak; Raina Rupesh
Description
An account of the resource
Renal cell carcinoma (RCC) is an aggressive and lethal tumor that has a high frequency of metastatic spread to unpredictable sites. One quarter of patients have either distant metastases or significant local-regional disease with atypical symptoms on presentation. We present a 41-year-old patient with symptoms of right heart failure and was found to have metastatic renal cell carcinoma with enhancing tumor from left renal vein up to right atrium.
Identifier
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<a href="http://doi.org/10.14740/cr690w" target="_blank" rel="noreferrer noopener">10.14740/cr690w</a>
Rights
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Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2018
Cardiology research
Department of Internal Medicine
Hegde Vinayak
Inferior vena cava
Khayata Mohamed
Lane Jason L
Metastasis
NEOMED College of Medicine
Raina Rupesh
Renal cell carcinoma
Right atrial mass
Shah Shilpi
Vinod Poornima
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.14740/cr560w" target="_blank" rel="noreferrer noopener">http://doi.org/10.14740/cr560w</a>
Pages
105–110
Issue
3
Volume
8
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Comparison of Clopidogrel With Prasugrel and Ticagrelor in Patients With Acute Coronary Syndrome: Clinical Outcomes From the National Cardiovascular Database ACTION Registry.
Publisher
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Cardiology research
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-06
Subject
The topic of the resource
Antiplatelet therapy; Coronary artery disease; Health care outcomes
Creator
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Khayata Mohamed; Gabra Joseph N; Nasser M Farhan; Litman George I; Bhakta Shyam; Raina Rupesh
Description
An account of the resource
BACKGROUND: We aimed to compare the clinical outcomes of clopidogrel, prasugrel, and ticagrelor in clinical practice using the National Cardiovascular Database ACTION Registry((R)). Treatment guidelines for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention recommend dual antiplatelet therapy (DAPT) for 12 months. Few clinical trials have compared the safety and efficacy of clopidogrel with that of newer antiplatelet therapies. METHODS: A retrospective study of patients hospitalized for ACS at Cleveland Clinic Akron General was conducted. Data elements included detailed medical history and clinical outcomes during hospital stay. The primary outcome was a composite of major clinical events (cardiogenic shock, atrial fibrillation, ventricular fibrillation, ventricular tachycardia, heart failure, bleeding, and mechanical ventilation). The independent variable was the type of DAPT. Statistical analyses were performed using Chi-square and Mann-Whitney U tests. A post-hoc analysis was performed to compare between the antiplatelet drugs head-to-head. RESULTS: Subjects (n = 1,388) admitted between January 2011 and March 2016 with ACS and treated with clopidogrel, prasugrel, or ticagrelor were included in the study. Mean age was 65 +/- 14 years and 46% had ST-segment elevation myocardial infarction. Prasugrel administration within 24 h was associated with a lower incidence of the composite outcome (P = 0.049), bleeding (P = 0.028), and heart failure (P = 0.002). CONCLUSION: There was a significant difference between the type of antiplatelet drug and clinical outcomes in ACS patients who were treated with DAPT. Observations from current study may provide important information for prescribers in clinical decision-making.
Identifier
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<a href="http://doi.org/10.14740/cr560w" target="_blank" rel="noreferrer noopener">10.14740/cr560w</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Antiplatelet therapy
Bhakta Shyam
Cardiology research
Coronary Artery Disease
Department of Internal Medicine
Gabra Joseph N
Health care outcomes
Khayata Mohamed
Litman George I
Nasser M Farhan
NEOMED College of Medicine
Raina Rupesh
-
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.14740/cr553w" target="_blank" rel="noreferrer noopener">http://doi.org/10.14740/cr553w</a>
Pages
87–95
Issue
3
Volume
8
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Cardiorenal Syndrome: Role of Arginine Vasopressin and Vaptans in Heart Failure.
Publisher
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Cardiology research
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
2017-06
Subject
The topic of the resource
Arginine vasopressin; Cardiorenal syndrome; Conivaptan; Heart failure; Tolvaptan; Vaptans; Vasopressin receptor antagonists
Creator
An entity primarily responsible for making the resource
Vinod Poornima; Krishnappa Vinod; Chauvin Abigail M; Khare Anshika; Raina Rupesh
Description
An account of the resource
Heart and kidney failure continued to be of increasing prevalence in today's society, and their comorbidity has synergistic effect on the morbidity and mortality of patients. Cardiorenal syndrome (CRS) is a complex disease with multifactorial pathophysiology. Better understanding of this pathophysiological network is crucial for the successful intervention to prevent advancement of the disease process. One of the major factors in this process is neurohormonal activation, predominantly involving renin-angiotensin-aldosterone system (RAAS) and arginine vasopressin (AVP). Heart failure causes reduced cardiac output/cardiac index (CO/CI) and fall in renal perfusion pressures resulting in activation of baroreceptors and RAAS, respectively. Activated baroreceptors and RAAS stimulate the release of AVP (non-osmotic pathway), which acts on V2 receptors located in the renal collecting ducts, causing fluid retention and deterioration of heart failure. Effective blockade of AVP action on V2 receptors has emerged as a potential treatment option in volume overload conditions especially in the setting of hyponatremia. Vasopressin receptor antagonists (VRAs), such as vaptans, are potent aquaretics causing electrolyte-free water diuresis without significant electrolyte abnormalities. Vaptans are useful in hypervolemic hyponatremic conditions like heart failure and liver cirrhosis, and euvolemic hyponatremic conditions like syndrome of inappropriate anti-diuretic hormone secretion. Tolvaptan and conivaptan are pharmaceutical agents that are available for the treatment of these conditions.
Identifier
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<a href="http://doi.org/10.14740/cr553w" target="_blank" rel="noreferrer noopener">10.14740/cr553w</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Arginine vasopressin
Cardiology research
Cardiorenal syndrome
Chauvin Abigail M
Conivaptan
Department of Internal Medicine
Heart failure
Khare Anshika
Krishnappa Vinod
NEOMED College of Graduate Studies Student
NEOMED College of Medicine
Raina Rupesh
Tolvaptan
Vaptans
Vasopressin receptor antagonists
Vinod Poornima