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Tags: Carrier Proteins/*antagonists & inhibitors

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Inhibition of striatal dopamine transporter activity by 17beta-estradiol.

Striatal synaptosomes from ovariectomized rats were prepared to examine the effect of 17beta-estradiol on [3H]dopamine uptake. Estradiol inhibited [3H]dopamine uptake in a dose-dependent manner, with an IC50 of 7.2 microM. Use of identical…

Tags: *Membrane Glycoproteins, *Membrane Transport Proteins, *Nerve Tissue Proteins, 1998, Animals, Boja J W, Carrier Proteins/*antagonists & inhibitors, Disshon K A, Dluzen D E, Dopamine Plasma Membrane Transport Proteins, Dopamine/metabolism, Estradiol/*pharmacology, European journal of pharmacology, Female, Neostriatum/*drug effects/metabolism, Rats, Sprague-Dawley, Synaptosomes/*drug effects/metabolism

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