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Tags: Cell Death/*physiology

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Autoschizis: a novel cell death.

Vitamin C (VC) and vitamin K(3) (VK(3)) administered in a VC:VK(3) ratio of 100:1 exhibit synergistic antitumor activity and preferentially kill tumor cells by autoschizis, a novel type of necrosis characterized by exaggerated membrane damage and…

Tags: 2002, Animals, Antioxidants/chemistry/*pharmacology/therapeutic use, Ascorbic Acid/chemistry/*pharmacology/therapeutic use, Biochemical pharmacology, Calderon Pedro Buc, Cell Death/*physiology, Gilloteaux Jacques, Humans, Jamison James M, Necrosis, Neoplasms/drug therapy/metabolism/*pathology, Oxidative Stress/*drug effects, Summers Jack L, Taper Henryk S, Vitamin K/chemistry/*pharmacology/therapeutic use

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